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02:33 EDT 18th August 2018 | BioPortfolio

The US National Library of Medicine and National Institutes of Health manage PubMed.gov which comprises of more than 21 million records, papers, reports for biomedical literature, including MEDLINE, life science and medical journals, articles, reviews, reports and  books.  BioPortfolio aims to publish relevant information on published papers, clinical trials and news associated with users selected topics.

For example view all recent relevant publications on Epigenetics and associated publications and clincial trials.

Showing PubMed Articles 1–25 of 1,000,000+

Ultrasound hyperthermia enhances chemo-sensitivity in oral squamous cell carcinoma by TRIF mediated pathway.

Hyperthermia is currently used as an alternative to surgery or in combination with chemotherapy and/or radiation therapy in the treatment of oral squamous cell carcinoma. However, little has been known about the change of chemo-sensitivity after hyperthermia and the mechanism underlie it in oral squamous cell carcinoma.

Biodiversity loss along a gradient of deforestation in Amazonian agricultural landscapes.

Assessing how much management of agricultural landscapes, in addition to protected areas, can offset biodiversity erosion in the tropics is a central issue for conservation that still requires cross-taxonomic and landscape-scale studies. We measured the effects of Amazonia deforestation and subsequent land-use intensification in 6 agricultural areas (landscape scale), where we sampled plants and 4 animal groups (birds, earthworms, fruit flies, and moths). We assessed land-use intensification with a syntheti...

Out-of-pocket expenditure for health care: District level estimates for Haryana state in India.

In this paper, we present district level out-of-pocket (OOP) expenditures with respect to outpatient consultation within last 15 days and hospitalization in last 1 year for Haryana state.

GIS-based method to delimit spheres of influence for a medical consortium: Experience of a pediatric medical consortium, Shanghai.

To improve the utilization efficiency of health care services, the concept of a "regional medical consortium" has attracted more attention during the most recent round of health care reform in China. Shanghai, a municipality of China, has made many efforts to promote its regional medical consortium project. In this paper, the pediatric medical consortium of Shanghai will serve as an example to introduce the main tasks and groundwork of the Shanghai medical consortium and will underscore Shanghai's explorati...

All-Inorganic Perovskite CsSnBr3 as a Thermally Stable, Free-Carrier Semiconductor.

Hybrid organic-inorganic perovskites, especially methylammonium lead triiodide (MAPbI3), are intensely studied for their optoelectronic properties. The organic MA+ cation is held responsible for the superior performance of MAPbI3 but also its instability toward moisture and heat. To explore compositions beyond MAPbI3, we performed experiments and calculations on two isomorphous perovskites CsSnBr3 and MASnBr3. CsSnBr3 is slightly smaller than MASnBr3 in cell dimension, but outperforms MASnBr3 in bandgap ene...

Unique Supramolecular Liquid Crystal Phases with Different Two-Dimensional Crystal Layers.

We report here a series of tetrablock-mimic azobenzene-containing fullerene dyads that form phase segregated two-dimensional (2D) crystal constructed supramolecular liquid crystals (LCs). The unique double-, triple- and quadruple-layer packing structure of fullerenes in 2D crystals leads to different smectic supramolecular LC phases, and novel LC phase transitions are observed due to the change of fullerene packing layer number in 2D crystals. Interestingly, by combining the LC properties with 2D crystals, ...

Optimization of the 2014 Gleason grade grouping in a Canadian cohort of patients with localized prostate cancer.

To evaluate the 5-tier grouping for Gleason scoring (GG) of prostate cancers adopted by the International Society of Urology Pathology (ISUP) in 2014, and to propose modifications to optimize its performance.

Mixed-methods content and sentiment analysis of adolescents' voice-diaries describing daily experiences with asthma and self-management decision-making.

Accurate symptom assessment remains challenging in teen populations. Little is known of usual symptom/response patterns, and self-reported paper diaries have traditionally low compliance rates. Therefore, we used concurrent digital voice-diaries to capture daily asthma experiences.

Quantitative analysis of apically extruded bacteria following preparation of curved canals with three systems.

This study compared the amount of apically extruded bacteria following preparation of curved root canals using two continuously rotating multifile and one reciprocating single-file systems. Mesiobuccal canals from maxillary molars were contaminated with Enterococcus faecalis and divided into three groups according to the instrumentation system: Reciproc (R25 instrument, 25/.08), BT-RaCe (10/.06, 35/.00 and 35/.04), and Mtwo (25/.06, 30/.05 and 35/.04). Apically extruded material was collected by a customize...

Classification and cyclic fatigue evaluation of new kinematics for endodontic instruments.

This study evaluated the effect of new motions of the motor TriAuto ZX2 on the cyclic fatigue of endodontic instruments. Vortex Blue 35.06 instruments were divided into four groups (n = 10) and tested for fatigue in a curved artificial canal (90° and 2 mm radius) using the following motions: continuous rotation (CR), Optimum Torque Reverse (OTR) set at 180° and the Optimum Glide Path (OGP), which was tested at 90° and 240°. The time to fracture (TTF) and the lengths of the fractured fragments were re...

Antimicrobial efficacy of clindamycin and triple antibiotic paste as root canal medicaments on tubular infection: An in vitro study.

This study compared the antibacterial effect of 2% clindamycin and 2% and 100% concentration of triple antibiotic paste (TAP) on an Enterococcus faecalis biofilm. Dentinal tubules of 100 root specimens were infected and randomly assigned to five groups. A total of 1000 mg mL of TAP, 20 mg mL of TAP and clindamycin, calcium hydroxide or methylcellulose (control) were placed in the root canal for 1 week. After treatment, dentine shavings were collected from 200 and 400 μm dentine depth and the number o...

Macroscale Analysis of Mistletoe Host Ranges in the Andean-Patagonian Forest.

The number of host species infected by a mistletoe (host range) is critical in that it influences prevalence, virulence and overall distribution of the parasite; however, macroecological analyses of this life history feature are lacking for many regions. The Andean-Patagonian forest, found along the southern Andes from 35˚S to Tierra del Fuego 55˚S, contains twelve mistletoe species in three families (Loranthaceae, Misodendraceae and Santalaceae). By tabulating herbarium records, the host ranges and geogr...

Probabilistic classification of tumour habitats in soft tissue sarcoma.

The purpose of this work is to propose a method to characterize tumour heterogeneity on MRI, using probabilistic classification based on a reference tissue. The method uses maps of the apparent diffusion coefficient (ADC), T relaxation, and a calculated map representing high-b-value diffusion-weighted MRI (denoted simDWI) to identify up to five habitats (i.e. sub-regions) of tumours. In this classification method, the parameter values (ADC, T , and simDWI) from each tumour voxel are compared against the cor...

Calcifying epithelial odontogenic tumours: collaborative study of 32 cases and review of literature.

To analyse the occurrence of calcifying epithelial odontogenic tumours (CEOT) based on biopsy records from different Brazilian geographic regions and to contrast the data with a review of the literature.

Endodontic treatment of a hypertaurodontic mandibular left second molar in a patient with many taurodonts combined with multiple pulp stones.

Taurodontism is a rare embryologic anomaly of teeth, defined by an apical displacement of the furcation of roots and enlarged pulp chambers. Taurodontism has been classified as hypo-, meso- or hypertaurodontism according to the severity of the anomaly. The aim of this case report was to illustrate a clinical case with multiple bilateral taurodonts and to describe the endodontic management of the hypertaurodontic mandibular left second molar with a C-shaped canal and extensive dental pulp calcifications. A h...

Undergraduate dentistry students' perception of difficulties regarding endodontic treatment.

The present study aimed to identify students' perceptions of endodontic treatment at a Brazilian university through a survey, which analysed student profiles and their difficulties in 2016. One hundred and two students who had experienced endodontic, laboratory or clinical procedures answered a survey based on their experiences, regarding their perceptions, experience and self-confidence levels. Results demonstrated that there was no significant difficulty among students regarding anaesthesia, rubber dam us...

Effectiveness of calcium and sodium hypochlorite in association with reciprocating instrumentation on decontamination of root canals infected with Enterococcus faecalis.

The aim of this study was to evaluate the antimicrobial activity of sodium and calcium hypochlorite utilising reciprocating instrumentation. Sixty root canals were inoculated with E. faecalis for 14 days. Samples were divided into six groups according to decontamination protocol: G1: no treatment, G2: distilled water, G3: 2.5% sodium hypochlorite, G4: 2.5% calcium hypochlorite, G5: 5.25% sodium hypochlorite and G6: 5.25% calcium hypochlorite. Instrumentation was performed with Wave One reciprocating syste...

Highly Flexible and Efficient All-Polymer Solar Cells with High-Viscosity Processing Polymer Additive toward Potential of Stretchable Devices.

Considering the potential applications of all-polymer solar cells (all-PSCs) as wearable power generators, it is urgent to develop photoactive layers that possess intrinsic mechanical endurance while maintaining a high power-conversion efficiency (PCE). We herein demonstrate a strategy to simultaneously control the intercalation behavior and nanocrystallite size in the polymer-polymer blend by using a newly developed high-viscosity polymeric additive, poly(dimethylsiloxane-co-methyl phenethylsiloxane) (PDPS...

Cationic Complexes of Boron and Aluminum - An Early 21st Century Viewpoint.

Boron and aluminum share one main group, they are found in daily life commodities, and considered environmentally benign. Nevertheless, they markedly differ in their element properties (e.g. metal character, atomic radius). The use of Lewis acidic complexes of boron and aluminum for methods of bond activation and catalysis (e.g. hydrogenation of unsaturated substrates, polymerization of olefins and epoxides) is quickly expanding. The introduction of cationic charge may boost the metalloid-centered Lewis aci...

Discovery of layered indium hydroxide via a hydroperoxyl anion coordinated precursor at room temperature.

All reported layered metal hydroxides have brucite-like metal-hydroxyl host layers and the discovery of other types of layered metal hydroxides can significantly extend the layered metal hydroxide families, which is meaningful in both theory and applications. Here through hydroperoxyl anion coordinated In3+ cations as a precursor, we synthesized layered indium hydroxide which only existed as a three-dimensional cubic phase before. The layer of the product exhibits an unusual structure where In(OH)6 octahedr...

Interactions Between the Perception of Light and Temperature.

Expanding the acceptable range of indoor temperatures allows to reduce building energy consumption and may be beneficial for health. Therefore, we explored whether light conditions can be used to influence thermal perception under various ambient temperatures. In two laboratory experiments we tested the effect of the correlated colour temperature of light (2700 K and 5800 K) and its intensity (5 lux and 1200 lux) on thermal perception. The light exposures were provided during cool, neutral and warm thermal ...

Effect of sleep bruxism duration on perceived sleep quality in middle-aged subjects.

Sleep-related bruxism may directly impact sleep quality. This study aims to evaluate potential relationships between sleep bruxism events and related daytime symptoms. We investigated 22 patients (42.1 ± 11.6 yr of age) with sleep bruxism in comparison with 12 good sleeper control subjects of similar age (41.0 ± 11.5 yr). Sleep bruxism was visually analyzed and categorized according to sleep stage, bruxism type (tonic/phasic) and duration. Clinical instruments comprised the Epworth Sleepiness, the Brugman...

Total Synthesis, Stereochemical Assignment and Divergent Enantioselective Enzymatic Recognition of Larreatricin.

Recognise your mirror image: We report a concise and efficient total synthesis of the lignan natural product larreatricin as well as an unambiguous assignment of configuration of its enantiomers. Enzyme kinetic studies reveal that different families of polyphenol oxidases show high and remarkably divergent enantioselectivity in their recognition of this secondary metabolite.

Efficient Synthesis of Polysubstituted Pyrroles Based on 3+2 Cycloaddition Strategy Utilizing 1,2-Phospha-Brook Rearrangement under Brønsted Base Catalysis.

An efficient method for the synthesis of polysubstituted pyrroles was established based on the [3+2] cycloaddition strategy utilizing the [1,2]-phospha-Brook rearrangement under Brønsted base catalysis. The less-explored approach of the [3+2] cycloaddition, i.e., the reaction of a C3 subunit with imines, was successfully achieved by making use of newly designed C3 subunits containing the requisite umpolung. The two-step [3+2] cycloaddition involves the catalytic generation of an α-oxygenated propargyl ani...

Adding vibration to high-intensity intervals increase time at high oxygen uptake in well-trained cyclists.

The importance of accumulated time ≥90% of maximal oxygen consumption (VO ) to improve performance in well-trained endurance athletes is well established. The present study compared the acute effects of adding vibrations (VIB; 40 Hz) to the work intervals during a high-intensity cycling session (HIT) with a traditional HIT session without vibration (TRAD) on time ≥90% of VO , time ≥90% of peak heart rate (HR ), electromyography (EMG) activity and mean power in well-trained cyclists (n=10, VO =78.6±7....


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