PubMed Journals Articles About "Cutting Edge Cancer Detection" - Page: 2 RSS

10:48 EDT 21st October 2019 | BioPortfolio

Cutting Edge Cancer Detection PubMed articles on BioPortfolio. Our PubMed references draw on over 21 million records from the medical literature. Here you can see the latest Cutting Edge Cancer Detection articles that have been published worldwide.

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Showing "Cutting Edge Cancer Detection" PubMed Articles 26–50 of 23,000+

Developing a Cancer-Focused Library Survey - Assessing the Current Environment and Planning for the Future.

The primary goal of this project is to understand how each National Cancer Institute-designated cancer center library, and all libraries that support cancer research, function within their institutions. Through an in-depth survey focused on three major areas (staff, content and tools procurement, and user services), the research team hopes to determine how a cancer-centric library can be successful in supporting quality patient care, research excellence, and education. Additionally, the survey will examine ...

Prostate cancer biomarkers detection using nanoparticles based electrochemical biosensors.

Prostate cancer (PCa) is the most prevalent cancer with a high mortality rate. The early and accurate detection of PCa can significantly reduce mortality and saves lives. Hence, the nanomaterials based electrochemical nano-biosensors for PCa biomarkers will be the excellent alternative for diagnosis, detection and management of disease condition. In this review, we present a concise summary of the latest attainment and advancement in the use of nanoparticles for the diagnosis of PCa biomarkers. This review ...

World health status 1950-2015: Converging or diverging.

To advance the goal of "Grand Convergence" in global health by 2035, this study tested the convergence hypothesis in the progress of the health status of individuals from 193 countries, using both standard and cutting-edge convergence metrics.

Partnering with District Hospitals in India for Fight Against Cancer.

Cancer is a difficult disease to treat particularly in low socioeconomic strata. There are three major challenges: that of early detection, of affordability and easy accessibility to specialised health care. The complexity of health care delivery, lack of structured grassroots level training program for early cancer detection, the shortage of well-equipped hospitals compounds the challenge of detecting as well as treating cancer in village based India. We have tried to reach out to rural population, through...

Breast Cancer Early Detection: An Academic-Community Partnership in the Philippines.

A high proportion of patients with breast cancer in the Philippines present at an advanced stage and have a rapid, unfavorable outcome. Providing breast cancer education and early detection to this population is important to help reduce this health disparity. This article describes the impact of a train-the-trainer program, with mission groups traveling to the Philippines to promote female residents' breast cancer awareness, knowledge, and intent for future screening.

Recent Advances on Electrochemical Biosensing Strategies toward Universal Point of Care Systems.

A number of very recently developed electrochemical biosensing strategies are promoting electrochemical biosensing systems into practical point-of-care applications. Focus of research endeavors in biosensing community has transferred from detection of a specific analyte to the development of general biosensing strategies that can be applied for a single category of analytes, such as nucleic acid, protein and cell. In this review, we describe most recent cutting-edge researches on electrochemical biosensing ...

Recent advances in biosensor for detection of lung cancer biomarkers.

Lung cancer is primary cancer threatening human life worldwide with the highest mortality rate. The early detection of lung cancer plays a critical role in the early diagnosis and subsequent treatment. However, the conventional methodologies limit the applications due to the low sensitivity, being expensive, and invasive procedure. Tumor markers as biochemical parameters can reflect cancer occurrence and progression, which show sensitivity, convenience, and low cost in developing biosensors, and act as good...

Urine and Serum Exosomes as Novel Biomarkers in Detection of Bladder Cancer.

The gold standard for initial clinical diagnosis of bladder cancer involves cystoscopic examination of bladder and histological evaluation of tissues. There is a critical need to identify non-invasive and sensitive biomarkers. Early detection is essential challenge in diagnosis and surveillance of bladder carcinoma. Exosomes are nano- sized vesicles present in many biological fluids and have significant role in cancer. Thus, quantification of exosomes in different stages of bladder cancer may be of critical...

Difference in Physician- and Patient-Dependent Factors Contributing to Adenoma Detection Rate and Serrated Polyp Detection Rate.

Adenoma detection rate (ADR) is correlated with the risk of interval colorectal cancer and is considered as a quality benchmark for colonoscopy. Serrated polyp detection rate (SPDR) might be a more stringent indicator of quality in polyp detection.

The "-omics" facet of melanoma: Heterogeneity of genomic, proteomic and metabolomic biomarkers.

In the recent decade, cutting edge molecular and proteomic analysis platforms revolutionized biomarkers discovery in cancers. Melanoma is the prototype with over 51,100 biomarkers discovered and investigated thus far. These biomarkers include tissue based tumor cell and tumor microenvironment biomarkers and circulating biomarkers including tumor DNA (cf-DNA), mir-RNA, proteins and metabolites. These biomarkers provide invaluable information for diagnosis, prognosis and play an important role in prediction o...

On Leading and Trailing Edge: Toward a New Conceptualization of What Is Curative in Psychoanalysis.

This paper seeks to establish that the therapeutic action of psychoanalysis derives from two sources: the work with the trailing edge and the work with the leading edge, concepts introduced by Tolpin. While the work with the trailing edge or the repetitive transference is what psychoanalysis has always focused on when defining the therapeutic action, the work with the leading edge, for which the concept of the generative transference is introduced, has remained underdeveloped.

M-TAP Dance: Targeting PRMT1 and PRMT5 Family Members to Push Cancer Cells Over the Edge.

In this issue of Cancer Cell, Fedoriw and colleagues characterize a potent reversible inhibitor of type I PRMTs, GSK3368715, with anti-proliferative effects on numerous cancer types. Using a combination of GSK3368715 with PRMT5 inhibitors, the authors show that a threshold of overall arginine methylation reduction needs to be achieved for synergistic anti-tumor activity.

Label-free detection of miRNA cancer markers based on terminal deoxynucleotidyl transferase-induced copper nanoclusters.

The variations in microRNA (miRNA) expression levels can be useful biomarkers for the diagnosis of different cancers. In this work, a label-free and sensitive fluorescent method for detection of miRNA-21 is described based on duplex-specific nuclease (DSN) assist target recycling and terminal deoxynucleotidyl transferase (TdT) induced copper nanoclusters (CuNCs). In the absence of target, the 3'-phosphorylated probe DNA cannot be hydrolyzed by DSN and extended by TdT, and failed to synthesizing fluorescent ...

Impact of tumor histology on detection of pelvic and para-aortic nodal metastasis with F-fluorodeoxyglucose-positron emission tomography in stage IB cervical cancer.

F-fluorodeoxyglucose-positron emission tomography (FDG-PET) detection of metastatic nodal disease is useful for guiding cervical cancer treatment but the impact of tumor histology is unknown. This study reports the detection of FDG avid pelvic and para-aortic lymph nodes in patients with early stage cervical cancer with squamous carcinoma and adenocarcinoma tumor histology.

A modified method for a customized harvest of fibula free flap in maxillofacial reconstruction.

Mandibular reconstruction using computer-aided design/computer-aided manufacturing cutting guides is currently a common procedure. However, inaccurate positioning of the cutting guide onto the fibular bone may result in osteosynthesis difficulties or imprecision in the reconstruction. a novel way to improve the stability of the cutting guides may be to add pillars in order for them to be suspended from the fibula, avoiding soft tissues interactions.We present the case of a 39-year-old male who needed mandib...

Early lesion detection with F-DCFPyL PET/CT in 248 patients with biochemically recurrent prostate cancer.

Prostate-specific membrane antigen (PSMA) PET/CT is increasingly used in patients with biochemically recurrent prostate cancer (BCR), mostly using gallium-68 (Ga)-labelled radiotracers. Alternatively, fluorine-18 (F)-labelled PSMA tracers are available, such as F-DCFPyL, which offer enhanced image quality and therefore potentially increased detection of small metastases. In this study we evaluate the lesion detection efficacy of F-DCFPyL PET/CT in patients with BCR and determine the detection efficacy as a ...

Early stage detection and screening of ovarian cancer: A research opportunity and significant challenge for biosensor technology.

Women diagnosed with late-stage ovarian cancer suffer a very high rate of mortality. Accordingly, it is imperative to detect and diagnose the disease as early as possible in its development. Achievement of this aim implies relatively large scale screening of women at an age of clinically significance through assay of biomarkers for disease present in blood or serum. Biosensor detection offers an attractive technology for the automated detection of such species. Among several biomarkers that have been identi...

Scientific abstracts for RhinoWorld 2019.

It has been a decade since the world's rhinologic community gathered in the United States for RhinoWorld. The American Rhinologic Society (ARS), International Rhinologic Society (IRS), and International Society of Inflammation and Allergy of the Nose (ISIAN) have joined together to host this international gathering of clinicians and scientists. Herein, you will find the abstracts that will be presented orally during RhinoWorld on June 5-9, 2019, in Chicago, IL. This IFAR supplement serves as an informationa...

The potential and controversy of targeting STAT family members in cancer.

The Signal Transducer and Activator of Transcription (STAT) family of proteins consists of transcription factors that play a complex and essential role in the regulation of physiologic cell processes, such as proliferation, differentiation, apoptosis and angiogenesis, and serves to organize the epigenetic landscape of immune cells. To date, seven STAT genes have been identified in the human genome; STAT1, STAT2, STAT3, STAT4, STAT5a, STAT5b and STAT6. They all account for diverse effects in response to extr...

Targeted biopsy of the prostate: improvement in detection of high-grade cancer, or the Will Rogers phenomenon?

The advent of targeted prostate biopsies to suspicious lesions based on imaging confers improved detection of clinically significant prostate cancer. The oversampling of these lesions is likely to better represent the cancer grade. However, such grade inflation might lead to the Will Rogers phenomenon. This study aims to investigate whether patients with Gleason 3+4 cancer on transrectal biopsy are upgraded following transperineal MRI-targeted biopsy & whether this has implications for current clinical prac...

Community-acquired pneumonia among children: the latest evidence for an updated management.

To provide cutting-edge information for the management of community-acquired pneumonia in children under 5 years, based on the latest evidence published in the literature.

Resectable lung lesions malignancy assessment and cancer detection by ultra-deep sequencing of targeted gene mutations in plasma cell-free DNA.

Early detection of lung cancer to allow curative treatment remains challenging. Cell-free circulating tumour (ct) DNA (ctDNA) analysis may aid in malignancy assessment and early cancer diagnosis of lung nodules found in screening imagery.

Multiparametric MRI Multiparametric US in the Detection of Prostate Cancer.

The aim of the study was to compare the diagnostic accuracy of multiparametric magnetic resonance imaging (mpMRI), multiparametric ultrasound (mpUS) and US/MRI fusion imaging techniques in the detection of prostate cancer.

Five-year clinical outcomes after percutaneous edge-to-edge mitral valve repair: Insights from the multicenter GRASP-IT registry.

Limited evidence is available on 5-year clinical outcomes after percutaneous edge-to-edge mitral valve repair.

Combining the wisdoms of traditional medicine with cutting-edge science and technology at the forefront of medical sciences.

A central topic is to bring traditional medicine to a new horizon by integrating the latest advances in genomic, metabolomic, and system biological approaches, in order to re-examine the wisdom and knowledge of traditional Chinese medicine (TCM) and other traditional medicines.

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