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PubMed Journals Articles About "Human Medicines European Public Assessment Report EPAR Prevenar" - Page: 2 RSS

09:59 EST 13th November 2019 | BioPortfolio

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Showing "Human medicines European public assessment report EPAR Prevenar" PubMed Articles 26–50 of 44,000+

European Public Health News.


European Public Health News.

Nurse-led medicines' monitoring in care homes, implementing the Adverse Drug Reaction (ADRe) Profile improvement initiative for mental health medicines: An observational and interview study.

Preventable adverse effects of medicines often pass unnoticed, but lead to real harm.


Assessing National Public Health Law to Prevent Infectious Disease Outbreaks: Immunization Law as a Basis for Global Health Security.

Immunization plays a crucial role in global health security, preventing public health emergencies of international concern and protecting individuals from infectious disease outbreaks, yet these critical public health benefits are dependent on immunization law. Where public health law has become central to preventing, detecting, and responding to infectious disease, public health law reform is seen as necessary to implement the Global Health Security Agenda (GHSA). This article examines national immunizatio...

The effects of inulin on gut microbial composition: a systematic review of evidence from human studies.

Inulin, consisting of repetitive fructosyl units linked by β(2,1) bonds, is a readily fermentable fiber by intestinal bacteria that generates large quantities of short-chain fatty acids (SCFA). In individuals with constipation, it was reported that inulin ingestion was associated with a significant increase in stool frequency, suggesting a potential impact of inulin on human gut microbiota composition. Progress in high-throughput technologies allow assessment of human-associated microbiomes in terms of div...

Medicines shortages.

Body of evidence and approaches applied in the clinical development program of fixed-dose combinations in the European Union from 2010-2016.

To provide insights into the clinical development pathway for fixed-dose combinations (FDCs), to consider strategies, and to elucidate the path to approval by assessing the body of evidence, as summarized in the European Public Assessment Reports (EPARs).

Immediate response to major incidents: defining an immediate responder!

There is a gap in time between the occurrence of a mass casualty incident (MCI) and the arrival of the first responders to the scene, which offers an opportunity for the public (immediate responders) to perform life-saving measures. The purpose of this study was to identify these measures and the public's willingness to conduct them.

Mapping novel psychoactive substances policy in the EU: The case of Portugal, the Netherlands, Czech Republic, Poland, the United Kingdom and Sweden.

The rapid rise in trade and use of NPS and the lack of information concerning their potential toxicity pose serious challenges to public health authorities across the world. Policy measures towards NPS taken so far have a special focus on their legal status, while the implementation of a public health strategy seems to be still missing. The aim of this study is to perform a general assessment of NPS-related policy (including regulatory measures and public health strategies) implemented by six European count...

Levels and human health risk assessment of heavy metals in surface soil of public parks in Southern Ghana.

This study evaluates the extent to which humans may be exposed to health risk from heavy metals in surface soils of public parks in Southern Ghana during outdoor activities. The study investigated surface soils of 56 public parks from seven metropolitan cities in Southern Ghana. Heavy metals (Cd, Cr, Cu, Hg, Mn, Ni, Pb, and Zn) were determined using microwave-assisted HNO-HF acid digestion and atomic absorption spectroscopy with flame, graphite furnace, and cold vapor options. All parks studied registered t...

Neonatal Eating Assessment Tool-Breastfeeding: Reference Values for Infants Less Than 7 Months old.

The Neonatal Eating Assessment Tool-Breastfeeding is a valid and reliable 62-item parent-report assessment of symptoms of problematic breastfeeding behavior intended for infants less than 7 months old.

Medicinal products for geriatric patients in Germany : Current status of regulatory requirements and clinical reality.

Geriatric patients are the main users of medicinal products, although this patient group is most commonly excluded from clinical trials. Several guidelines from the International Conference on Harmonisation (ICH) and the European Medicines Agency (EMA) have tried to ensure the development and the safe use of medicines for geriatric patients.

The role of gut microbiota for the activity of medicinal plants traditionally used in the European Union for gastrointestinal disorders.

. Many medicinal plants have been traditionally used for the treatment of gastrointestinal disorders. According to the monographs published by the Committee on Herbal Medicinal Products (HMPC) at the European Medicines Agency, currently 44 medicinal plants are recommended in the European Union for the treatment of gastrointestinal disorders based on traditional use. The main indications are functional and chronic gastrointestinal disorders, such as functional dyspepsia and irritable bowel syndrome (IBS), an...

HMA/EMA medicines shortages guidance released.

Metals and metalloids in traditional medicines (Ayurvedic medicines, nutraceuticals and traditional Chinese medicines).

Traditional medicine (TM) including Ayurvedic medicines, traditional Chinese medicines and nutraceuticals are popular across the globe as dietary supplements and traditional and alternative medicines. Health risks from these remedies continue to present serious concerns, with occurrences of poisoning by metals and metalloids present at concentrations above acceptable regulatory standards. This review overviews the prevalence of TM use, cases of metal and metalloid poisoning following TM consumption, and for...

Effect on Treatment Adherence of Distributing Essential Medicines at No Charge: The CLEAN Meds Randomized Clinical Trial.

Nonadherence to treatment with medicines is common globally, even for life-saving treatments. Cost is one important barrier to access, and only some jurisdictions provide medicines at no charge to patients.

Availability in hospitals of medicines for acute cases.

Availability in hospitals of medicines for acute cases In acute situations it is important that essential medication is readily available. In this comment we discuss various challenges in determining the assortment of medicines that should be available, and the logistic and administrative obstacles for pharmacists when delivering unregistered medicines such as artesunate. With centralization of (emergency) care, we must ask ourselves whether every hospital pharmacy should have a wide range of medicines in s...

Extension of the European Medicines Agency (EMA) approval of trifluridine/tipiracil for gastric cancer.

The Dutch Public Health Foresight Study 2018: an example of a comprehensive foresight exercise.

The use of foresight studies is common in some policy fields, but not in public health. Interest in such studies is growing. This paper gives a general overview of the Dutch Public Health Foresight Study (PHFS) 2018, providing insight into what performing a broad scenario exercise in the field of public health entails and its societal impacts.

National Academies of Sciences, Engineering, and Medicine report on genetically engineered crops influences public discourse.

In May 2016, the National Academies of Sciences, Engineering, and Medicine (NASEM) released the report "Genetically Engineered Crops: Experiences and Prospects," summarizing scientific consensus on genetically engineered crops and their implications. NASEM reports aim to give the public and policymakers information on socially relevant science issues. Their impact, however, is not well understood. This analysis combines national pre- and post-report survey data with a large-scale content analysis of Twitter...

France and marijuana: an unbalanced debate where public health competence is missing.

Household Pharmaceutical Waste Disposal in Selangor, Malaysia-Policy, Public Perception, and Current Practices.

Although pharmaceuticals treat illnesses and prevent diseases in humans and animals, ironically, they are now among the emerging pollutants in the environment. As individuals continue to consume medicines, households can become a primary source of pharmaceutical pollutants. This paper explains relevant Malaysian law and policy on the issue. Using a questionnaire survey, it also assesses public perception concerning the environmental impact of pharmaceutical waste and the current methods of disposal that are...

Human intestinal myiasis caused by Clogmia albipunctata larvae (Diptera: Psychodidae): First report in Egypt.

This is the first case report in Egypt and Middle East region of human intestinal myiasis caused by Clogmia albipunctata larvae. A 36-year-old male patient presented to the Outpatient Clinic of Internal Medicine in Beni-Suef University Hospital complaining of abdominal pain, bloating, and diarrhea intermittent with constipation. Patient's stool sample was referred to the Department of Medical Parasitology for examination of passed larvae and treatment prescription. Examination of larvae by light and scannin...

Impact of risk minimisation measures on the use of strontium ranelate in Europe: a multi-national cohort study in 5 EU countries by the EU-ADR Alliance.

In May 2013 and March 2014, the European Medicines Agency (EMA) issued two decisions restricting the use of strontium ranelate (SR). These risk minimisation measures (RMM) introduced new contraindications and limited the indications of SR therapy. The EMA required an assessment of the impact of RMMs on the use of SR in Europe. Methods design: multi-national, multi-database cohort Setting: electronic medical record databases based on hospital (Denmark) and primary care provenance (Italy, Spain, the Netherlan...

Gene therapy matures to medicines.


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