PubMed Journals Articles About "There Other Places Form Biotech Companies Than Boston" - Page: 2 RSS

11:08 EST 18th February 2019 | BioPortfolio

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Showing "There Other Places Form Biotech Companies than Boston" PubMed Articles 26–50 of 6,200+

Top-Funded Digital Health Companies And Their Impact On High-Burden, High-Cost Conditions.

Digital health companies hold promise to address major health care challenges, though little has been published on their impact. We identified the twenty top-funded private US-based digital health companies to analyze their products and services, related peer-reviewed evidence, and the potential for impact on patients with high-burden conditions. Data analytics (including artificial intelligence and big data) was the most common company type. Companies producing biosensors had the greatest funding. Publicat...

Spatial relationships among public places frequented by families plagued by methicillin-resistant Staphylococcus aureus.

To understand factors associated with community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) acquisition and infection, we mapped public places (including personal service establishments, fitness centers, pools, schools, and daycares) visited by members of households affected by CA-MRSA skin and soft tissue infection.

Cohort profile: The Boston Hospital Workers Health Study (BHWHS).

Boston Type I Keratoprosthesis: Antibacterial Resistance and Microbiota Evaluation of Soft Contact Lenses.

The Polish version of the Boston Carpal Tunnel Questionnaire: Associations between patient-rated outcome measures and nerve conduction studies.

The aim of this study was to investigate the associations between nerve conduction studies and three commonly used patient-reported outcome measures (Disabilities of the Arm, Shoulder and Hand [DASH], Michigan Hand Outcomes Questionnaire [MHQ], and the Polish version of the Boston Carpal Tunnel Questionnaire [BCTQ]) METHODS: A total of 218 consecutive patients with carpal tunnel syndrome (CTS) completed the BCTQ, MHQ, and DASH questionnaires followed by nerve conduction studies on their first visit to the c...

A New Hydrate of Cyclosporine: Structural and Physicochemical Characterization.

This work highlights a new orthorhombic hydrate (Form 2) of cyclosporine (CsA), a widely used immunosuppressant. The uniqueness of this new form was established by powder X-ray diffractometry (XRPD), solid-state nuclear magnetic resonance spectroscopy (SSNMR) and single crystal X-ray diffraction (SCXRD) analysis. The crystal structure of this form was solved (P222, a = 12.639 Å, b = 19.758 Å, c = 29.568 Å, Z =4). Also, the solid-state properties of Form 2 were compared with other known crystalline forms ...

Multiscale heterogeneity in filamentous microbes.

Microbial cells within clonal populations can display different morphologies or carry out different tasks. This heterogeneity is beneficial at the population level and allows microbes to spread risk or separate incompatible activities. Heterogeneity is also evident in filamentous bacteria and fungi, which form mycelial networks consisting of interconnected hyphae. Here, heterogeneity is observed between clonal mycelial particles, between different zones of colonies, between adjacent hyphae and even between ...

Structural Dynamics of PET-degrading Cutinase-like Enzyme from Saccharomonospora viridis AHK190 in Substrate-bound States Elucidates Ca Driven Catalytic Cycle.

A cutinase-type polyesterase from Saccharomonospora viridis AHK190 (Cut190) has been shown to degrade the inner block of polyethylene terephthalate. A unique feature of Cut190 is that its function and stability are regulated by Ca binding. Our previous crystal structural analysis of Cut190S226P has shown that one Ca ion binds to the enzyme, which induces large conformational changes in several loop regions to stabilize an open conformation ( Appl. Microbiol. Biotech. 2015, 99, 4297). In this study, to analy...

Predicting the Structures of Glycans, Glycoproteins, and Their Complexes.

Complex carbohydrates are ubiquitous in nature, and together with proteins and nucleic acids they comprise the building blocks of life. But unlike proteins and nucleic acids, carbohydrates form nonlinear polymers, and they are not characterized by robust secondary or tertiary structures but rather by distributions of well-defined conformational states. Their molecular flexibility means that oligosaccharides are often refractory to crystallization, and nuclear magnetic resonance (NMR) spectroscopy augmented ...

A Supplement to TRANSFUSION Abstract Presentations from the AABB Annual Meeting Boston, MA, October 13-16, 2018.

Faces Places.

Polymorphic phase transitions in carbamazepine and 10,11-dihydrocarbamazepine.

Temperature-induced phase transitions in carbamazepine (CBZ) and 1,10-dihydrocarbamazepine (DHC) were studied by simultaneous differential scanning calorimetry - X-ray diffraction in this work. The transitions generally involve a transitional melt phase which is quickly followed by recrystallisation. The expansions of the unit cell as a function of temperature could be quantified and allow us to determine a directional order of stability in relation to the lattice constants. Dihydrocarbamazepine form II und...

Cultivation of an algae-bacteria consortium in wastewater from an industrial park: Effect of environmental stress and nutrient deficiency on lipid production.

Adoption of microalgae-sourced products depends on the economic feasibility. In the case of fatty acids, it is crucial to obtain high lipid yield, especially in the form of storage lipids (TAGs). However, the production of these lipids often comes into competition with the microalgae biomass, resulting in a decrease in growth. A microalgae culture integration project was conducted in an industrial park in Canada in order to cultivate microalgae from park's wastewaters and then obtain products from the bioma...

Why places with less malaria produce more drug-resistant strains.

Toxocara eggs in public places worldwide - A systematic review and meta-analysis.

Toxocariasis is a neglected tropical disease of humans. Although many studies have indicated or shown that environmental contamination with Toxocara species eggs is a major risk factor for toxocariasis in humans, there has been no comprehensive analysis of published data or information. Here, we conducted the first systematic review and meta-analysis of current literature to assess the global prevalence of Toxocara eggs in public places (including beaches, parks and playgrounds). We conducted searches of th...

Towards an integrated framework for understanding the links between inequalities and wellbeing of places in low and middle income countries.

As part of a larger research programme undertaking the development of a global index of wellbeing (GLOWING) through the exploration of population wellbeing in low to middle income countries (LMICs), this paper examines the role of inequality in shaping experiences of wellbeing. The paper explores various conceptualizations of wellbeing and inequality and outlines an integrated framework for understanding the importance of measuring the wellbeing of places. We conclude by urging geographers to explicitly eng...

Social Media Posts by Recreational Marijuana Companies and Administrative Code Regulations in Washington State.

Recreational marijuana use was legalized in the state of Washington in 2012, and the Washington Administrative Code (WAC) 314-55-155 was implemented to limit the exposure of youths to marijuana advertisements.

Hello from the new TRANSFUSION offices in Boston.

Understanding the Phase Behavior of Energetically Similar Polymorphs to achieve Controlled Crystallization for a Nav1.7 Pain Inhibitor Compound.

GENE-A, a Nav1.7 inhibitor compound with analgesic activity was developed as a crystalline anhydrate, for which two polymorphic forms, I and II, were discovered. The two forms were found to possess very similar free energies as determined experimentally with Form II being thermodynamically stable above 292K (19C) based on solubility measurements. A detailed solid-state characterization was conducted to determine the relative stability of these solid forms, and both thermodynamic and kinetic pathways (slurry...

Seasonal mobility and well-being of older people: The case of 'Snowbirds' to Sanya, China.

Seasonal retired migrants have increased rapidly in developing countries in recent years. This article adopts a relational perspective to understand the relationships between older people's seasonal mobility and well-being. It shows that the complex spatiotemporal dynamics of seasonal mobility and the non-western sociocultural context influence older people's relations with their places of origin and destination, which in turn shape their well-being experiences during seasonal mobility. Narrative analysis o...

UTx With Deceased Donors Also Places Risks and Burdens on Third Parties.

An industry update: the latest developments in therapeutic delivery covering September 2018.

The present industry update covers the period 1-30 September 2018, with information sourced from company press releases, regulatory and patent agencies as well as scientific literature. Various technologies using reformulations of know drugs with nanoparticles, hydrogels, aerosols, etc. emerged in new financing rounds (BioTime; CA, USA, SiSaf; Guildford, UK, Cassion Biotech; TX, USA), intellectual property protection (TFF Pharmaceuticals; TX, USA), repackaging (Leiters; CA, USA) and reformulation (Virpax Ph...

New Challenges in Oncology for the Brazilian Private Health Sector: Specialists' Concerns After the ISPOR International Congress in Boston, Massachusetts, 2017.

The congress of the International Society for Pharmacoeconomics and Outcomes Research is one of the main worldwide forums for the dissemination of research and knowledge on healthcare economics. Brazil is the largest country in Latin America, with a per-capita gross domestic product of $15 200 in 2017 and healthcare expenditure of the order of $1 318 per inhabitant. Brazilian specialists participated actively in the society's latest congress, which took place in Boston, Massachusetts, from May 20 to 24, 201...

Why Cities Survive and Companies Die.

As systems evolve over time, their natural tendency is to become increasingly more complex. Studies in the field of complex systems have generated new perspectives on the application of management strategies in health systems. Much of this research appears as a natural extension of the cross-disciplinary field of systems theory. This article is the 5th in a series of articles that focuses on why technological complexity is increasing and strategies nurse administrators can use to successfully implement chan...

Development and validation of a discriminatory dissolution method for rifaximin products.

The commercial product of rifaximin (RFX) contains α form. The α form can change to β form on exposure to high humidity that can occur during manufacturing, stability and/or in-use period. It is critical to maintain α form of the drug in a drug product to avoid variability in clinical response. FDA dissolution method was found to be non-discriminatory for RFX formulations containing either 100 % α or β form. The objective of the study was to develop a discriminatory dissolution method that can detect ...

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