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Showing "pilot study released raises possibility that some young" PubMed Articles 26–50 of 64,000+

Do radiological research articles apply the term "pilot study" correctly? Systematic review.

To determine what proportion of radiological studies used the term "pilot" correctly.

The Effects of IL-1β on Astrocytes are Conveyed by Extracellular Vesicles and Influenced by Age.

The aging brain is associated with significant pathophysiological changes reflected in changes in astrocyte function. In this study, we hypothesized that the response of astrocytes to mechanical and inflammatory stimulation would differ with long-term culture. We report that naïve short-term cultured (young) and long-term cultured astrocytes (aged) exhibit similar recovery to a scratch wound assay. However, in response to IL-1β young astrocytes have an arrested recovery which is not observed in IL-1β tre...

Comparing the predictive capability of self-report and medically-verified non-fatal overdose in adults released from prison: A prospective data linkage study.

Self-reported non-fatal overdose (NFOD) is a predictor of future overdose and is often used to target overdose prevention for people released from prison. However, the level of agreement between self-reported and medically-verified NFOD history remains unknown. This study aimed to determine the agreement between, and predictive value of, self-reported and medically-verified history of NFOD in people recently released from prison.

A long-term evaluation of a training program on breaking bad news in pediatric neurosurgery: a pilot study.

Breaking bad news is a difficult task in medical practice. Several breaking-bad-news training programs have been proposed. However, long-term results of such training have rarely been investigated. The aim of this study was to compare the short- and long-term evaluations by young neurosurgeons of a training program for breaking bad news to patients and their parents.

Associations of air pollution, obesity and cardiometabolic health in young adults: The Meta-AIR study.

Growing evidence indicates exposure to air pollution contributes to obesity and cardiometabolic disease risk in children and adults, however studies are lacking in young adulthood, an important transitional period in the life course. The aim of this study was to examine the associations of short- and long-term regional ambient and near-roadway air pollution (NRAP) exposures on adiposity and cardiometabolic health in young adults aged 17-22 years.

What are constructive anxiety levels in wilderness therapy? An exploratory pilot study.

Participant state anxiety in outdoor therapeutic practices continues to raise many questions. To help inform this important topic we present and discuss the results of an exploratory pilot study on participant day-to-day state anxiety throughout a Norwegian wilderness therapy intervention.

Blunted circulating irisin in adults with type I diabetes during aerobic exercise in a hot environment: a pilot study.

Irisin is a novel myokine associated with increased metabolism, which may be upregulated in type 1 diabetes (T1D) during exercise-heat stress. We therefore assessed serum irisin production in young adults with and without T1D during incremental exercise in dry-heat (35°C). The change in irisin during exercise was lower in individuals with compared to without T1D (-1.79 [S.E.M. 25.68] vs. 59.74 [S.E.M. 79.63] pg/mL; p=0.024), indicating that irisin expression during exercise-heat stress is blunted in T1D. N...

A pilot exploratory study comparing the King-Devick test (KDT) during and between migraine attacks.

The King-Devick test is a timed rapid number naming task that involves complex cerebral functions. The objective of this pilot exploratory study is to determine whether there is a difference in the King-Devick test during a migraine attack compared to the interictal phase.

Culprit lesion morphology in young patients with ST-segment elevated myocardial infarction: A clinical, angiographic and optical coherence tomography study.

About 20% of patients with ST-segment elevated myocardial infarction (STEMI) are young adults. Morphological characteristics of culprit lesion in young STEMI patients have not been systematically evaluated in vivo. The present study aimed to investigate culprit lesion characteristics in young patients versus older patients using optical coherence tomography (OCT).

Young People's Perceptions of Sexual Assault in Residential Care: "It Does Happen a Lot".

The Australian Royal Commission into Institutional Responses to Child Sexual Abuse (the Royal Commission) examined child sexual abuse within a wide range of institutions that provide services to children, this included residential facilities. The current study (funded by the Royal Commission) considers young people's perception of safety in residential care; specifically, the current study attended to the voices of young people who spoke about sexual harassment and assault in qualitative interviews. Intervi...

A Mobile Intervention to Improve Uptake of Pre-Exposure Prophylaxis for Southern Black Men Who Have Sex With Men: Protocol for Intervention Development and Pilot Randomized Controlled Trial.

The uptake of pre-exposure prophylaxis (PrEP) has been slow for young black men who have sex with men (BMSM) living in the southern United States. This is a significant issue because 8 of the 10 states with the highest rates of new HIV infections are in the South. Jackson, Mississippi (MS), the site of this project, has the second highest AIDS diagnosis rate in the nation and the highest rate of HIV infection for young, urban BMSM. This study will develop and test an engaging, interactive, and cost-effectiv...

Attitudes Toward Depression in Arab-American Muslims: A Pilot Study.

Religion is said to play a strong role in the attitude toward health and disease in Arab and Muslim countries. To what extent this is also true of Arabs and Muslims living in the United States is unknown. The objective of this pilot study was to determine the influence of religious beliefs on the attitudes of Arab-American Muslims toward mental illness, especially depression.

Project profile: a multicenter study on breast cancer in young women in Latin America (PRECAMA study).

To describe the rationale and the methodology of a multicenter project to study the etiology of breast cancer in young Latin American women.

Unwanted Events Caused by Incorrectly Conducted Psychotherapy - A Pilot Study of the Inventory for the Assessment of Malpractice and its Consequences in Psychotherapy.

A pilot study was conducted to test a newly developed inventory for the assessment of malpractice in psychotherapy and its consequences. We aimed to examine the frequency of boundary crossings and violations in the context of psychotherapy from a patient's perspective and the resulting burden as well as to identify potential predictors.

Patient Co-Participation in Narrative Medicine Curricula as a Means of Engaging Patients as Partners in Healthcare: A Pilot Study Involving Medical Students and Patients Living with HIV.

This paper describes a pilot study of a new model for narrative medicine training, "community-based participatory narrative medicine" (CBPNM), which centers on shared narrative work between healthcare trainees and patients. Nine medical students and eight patients participated in one of two, five-week-long pilot workshop series. A case study of participants' experiences of the workshop series identified three major themes: (1) the reciprocal and collaborative nature of participants' relationships; (2) the i...

Experiences from the pilot implementation of the Package of Essential Non-communicable Disease Interventions (PEN) in Myanmar, 2017-18: A mixed methods study.

Myanmar adopted the World Health Organization (WHO) Package for Essential Non-Communicable Disease Interventions (PEN) in 20 pilot townships in 2017. This study was conducted to assess the implementation of PEN, its effectiveness and understand the facilitators and barriers in its implementation.

Fasting blood glucose and cerebrospinal fluid Alzheimer's biomarkers in non-diabetic cognitively normal elders: the CABLE study.

It is unclear how blood glucose levels mediate the pathology of Alzheimer's disease (AD). This study aimed to investigate whether fasting blood glucose (FBG) levels are associated with cerebrospinal fluid (CSF) biomarkers preferentially affected by AD in non-diabetic cognitively normal elders. A total of 499 non-diabetic cognitively normal elders were from the Chinese Alzheimer's Biomarker and LifestyLE (CABLE) study. We detected the associations of FBG with individual CSF measures using multiple linear reg...

Risk Factors and Outcomes of Very Young Adults Who Experience Myocardial Infarction: The Partners YOUNG-MI Registry.

Despite significant progress in primary prevention, the rate of myocardial infarction has not declined in young adults. We sought to compare the risk factor profiles and outcomes between individuals who experienced a first myocardial infarction at a very young (age ≤40) and young (40< age ≤50) age.

A Cognitive Behavioral Therapy Group for Adolescent and Young Adult Cancer Patients: A Review of a Pilot Program.

Adolescent and young adult (AYA-between ages 15 and 39) cancer patients face unique psychosocial challenges due to their developmental stage and complex health problems. Research indicates psychotherapy and group support can be beneficial to AYAs. Group therapy offers an opportunity for connection among peers who are enduring similar struggles while also utilizing effective therapeutic intervention. The current project describes a model for an AYA cognitive behavioral therapy (CBT) group. The model was info...

Changes in salivary oxytocin levels and bonding disorder in women from late pregnancy to early postpartum: A pilot study.

This pilot study aimed to 1) follow the longitudinal changes in the salivary oxytocin level of pregnant women from late pregnancy to early postpartum, 2) examine the factors related to these changes, and 3) clarify the association of these changes with mother-infant bonding.

A Daily Study Comparing Alcohol-Related Positive and Negative Consequences for Days With Only Alcohol Use Versus Days With Simultaneous Alcohol and Marijuana Use in a Community Sample of Young Adults.

Alcohol and marijuana are psychoactive substances commonly used by young adults and are independently associated with numerous acute and long-term consequences. Many young adults engage in simultaneous alcohol and marijuana (SAM) use to cross-fade (i.e., to enhance the effects of intoxication), although the extent to which alcohol use and alcohol-related consequences increase on SAM occasions compared to alcohol-only occasions is unclear. This study examines daily data among a sample of SAM users comparing ...

Glyphosate and nutrients removal from simulated agricultural runoff in a pilot pyrrhotite constructed wetland.

Pyrrhotite is often considered as a gangue mineral, and discarded in mine wastes and tailings. Glyphosate and fertilizer, often excessively used in agriculture, flow into water bodies with agriculture runoff, and cause pollution of water bodies. In this study, the pyrrhotite was used as a substrate in a pilot constructed wetland (CW) to remove the glyphosate and nutrients from simulated agriculture runoff. In nearly one year, the pilot pyrrhotite constructed wetland (Pyrr-CW) removed 90.3 ± 6.1% of gly...

Ustekinumab serum concentrations are associated with clinical outcomes in Crohn's disease - a regional multi-center pilot study.

 The role of therapeutic drug monitoring (TDM) in ustekinumab (UST) therapy for Crohn's disease (CD) has not been established, as only few studies have analyzed the relationship between UST serum concentrations and clinical outcome. In this pilot study, we retrospectively examined the potential of UST-concentrations (cUST) 8 weeks after induction (cUSTw8) to predict clinical response at week 16.

An assessment of Oxford Nanopore sequencing for human gut metagenome profiling: A pilot study of head and neck cancer patients.

Gut metagenome profiling using the Oxford Nanopore Technology (ONT) sequencer was assessed in a pilot-sized study of 10 subjects. The taxonomic abundance of gut microbiota derived from ONT was comparable with Illumina Technology (IT) for the high-abundance species. IT better detected low-abundance species through amplification, when material was limited.

Alcohol use in young adults associated with cortical gyrification.

Young adulthood has the highest rates of alcohol use and high-risk drinking behavior. This period is also a critical neurodevelopmental stage, with neural insults having a profound neurotoxic effect on the brain. Cortical gyrification is thought, in part, to reflect early brain maturation (e.g., hypogyrification in fetal alcohol syndrome). There is also evidence that cortical gyrification is sensitive to later-life events (e.g., fluctuations in malnutrition in young adults). However, no study has examined h...

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