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PubMed Journals Articles About "Tracking Clarifying Differential Traits Classical Atypical Type Bovine" - Page: 2 RSS

11:59 EDT 22nd July 2019 | BioPortfolio

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Showing "Tracking clarifying differential traits classical atypical type bovine" PubMed Articles 26–50 of 19,000+

Bacterial colonization of minerals in grassland soils is selective and highly dynamic.

Bacteria colonize reactive minerals in soils where they contribute to mineral weathering and transformation. So far, the specificity, patterns, and dynamics of mineral colonization have rarely been assessed under natural conditions. High throughput Illumina sequencing was employed to investigate the bacterial communities assembling on illite and goethite during exposure to natural grassland soils. Two different types of organic carbon sources, simple carbon compounds representing root exudates and detritus ...


Differences in blood pressure riser pattern is patients with acute heart failure with reduced mid-range and preserved ejection fraction.

Heart failure (HF) is classified into three types according to left ventricular ejection fraction (EF). The effect of blood pressure (BP) on the pathogenesis of each type is assumed to be different. However, the association between the prognosis of each type of HF and abnormal BP variations assessed by ambulatory BP monitoring (ABPM), such as nocturnal hypertension and the riser pattern, remains unclear.

Pattern of sympathetic vasomotor activity in a model of hypertension induced by nitric oxide synthase blockade.

We aimed to investigate the effects of nitric oxide (NO) synthesis inhibition by NO synthase inhibitor N-nitro-L-arginine-methyl ester (L-NAME) treatment on the sympathetic vasomotor nerve activity (SNA) on two sympathetic vasomotor nerves, the renal and splanchnic. NO plasma level and systemic oxidative stress were assessed. Hypertension was induced by L-NAME (20 mg/kg per day, by gavage, for seven consecutive days) in male Wistar rats. At the end of the treatment, blood pressure, heart rate, arterial bar...


Exploring the use of mobile information and communication technologies by people with mood disorders.

Information and communication technologies (ICTs) have become increasingly integrated into how care is delivered and received. However, no research has yet explored how people with mood disorders use mobile information and communication technologies (mICTs) in their everyday lives and, more specifically, how they might use mICTs to look after themselves. An exploratory qualitative study, within secondary and specialist mental health Services, was undertaken. Data generation involved in-depth, semi-structure...

Novel GLI3 variant causes Greig cephalopolysyndactyly syndrome in three generations of a Lithuanian family.

Preaxial polydactyly type IV, also referred as polysyndactyly, has been described in a few syndromes. We present three generations of a family with preaxial polydactyly type IV and other clinical features of Greig cephalopolysyndactyly syndrome (GCPS).

Use of Ambulatory Glucose Profile for Improving Monitoring and Management of T2DM.

To demonstrate glycemic variability in type 2 diabetic patients and consequent control of the same.

Population Structure and Dynamics of Helminthic Infection: Schistosomiasis.

While disease and outbreaks are mainly clonal for bacteria and other asexually reproducing organisms, sexual reproduction in schistosomes and other helminths usually results in unique individuals. For sexually reproducing organisms, the traits conserved in clones will instead be conserved in the group of organisms that tends to breed together, the population. While the same tools are applied to characterize DNA, how results are interpreted can be quite different at times (see another article in this collect...

Prevalence of Type II and Type III Workplace Violence against Physicians: A Systematic Review and Meta-analysis.

Workplace violence (WPV) in the health care sector remains a prominent, under-reported global occupational hazard and public health issue.

An evolutionary quantitative genetics model for phenotypic (co)variance under limited dispersal, with an application to socially synergistic traits.

Darwinian evolution consists of the gradual transformation of heritable traits due to natural selection and the input of random variation by mutation. Here, we use a quantitative genetics approach to investigate the coevolution of multiple quantitative traits under selection, mutation, and limited dispersal. We track the dynamics of trait means and variance-covariances between traits that experience frequency-dependent selection. Assuming a multivariate-normal trait distribution, we recover classical dynami...

Antimicrobial activity and structure of a consensus human β-defensin and its comparison to a novel putative hBD10.

The spread of multi-drug resistant bacteria owing to the intensive use of antibiotics is challenging current antibiotic therapies, and making the discovery and evaluation of new antimicrobial agents a high priority. The evaluation of novel peptide sequences of predicted antimicrobial peptides from different sources is valuable approach to identify alternative antibiotic leads. Two strategies were pursued in this study to evaluate novel antimicrobial peptides from the human β-defensin family (hBD). In the f...

A mouse model and F NMR approach to investigate the effects of sialic acid supplementation on cognitive development.

Researchers have observed that a sialic acid (Sia)-supplemented neonatal diet leads to improved cognition in weanling piglets. However, whether cognitive improvement appears with different physiological backgrounds and persists into adulthood is not known. Here, we have established a convenient mouse model and used an F NMR approach to address these questions, test the conditionally essential nutrient hypothesis about Sia supplementation, and assess the prospect of measuring Sia metabolism directly in vivo...

Lack of gene flow: narrow and dispersed differentiation islands in a triplet of Leptidea butterfly species.

Genome-scans in recently separated species can inform on molecular mechanisms and evolutionary processes driving divergence. Large-scale polymorphism data from multiple species pairs are also key to investigate the repeatability of divergence - if radiations tend to show parallel responses to similar selection pressures and/or underlying molecular forces. Here we used whole genome re-sequencing data from six wood white (Leptidea sp.) butterfly populations, representing three closely related species with kar...

The Healthier You: NHS Diabetes Prevention Programme: digital modes of delivery engage younger people.

Randomized control trials in those with impaired glucose tolerance have shown that the onset of Type 2 diabetes can be prevented or delayed through behavioural interventions that promote weight loss, increase physical activity, and improve the quality of nutrition. In 2016, the Healthier You: NHS Diabetes Prevention Programme was established to prevent or delay the onset of Type 2 diabetes in adults in England already identified to be at high risk, defined as having non-diabetic hyperglycaemia [HbA 42-47 mm...

Evaluating adaptive, carry-over and plastic antipredator responses across a temporal gradient in Pacific chorus frogs.

The development of antipredator traits is dependent on the frequency and intensity of predator exposure over evolutionary and ecological time. We hypothesized that prey species would respond with increasing accuracy when exposed to predators across generational, ontogenetic and immediate timescales. We assessed larval Pacific chorus frog (PSRE; Pseudacris regilla) individuals that varied in population sympatry, embryonic conditioning, and immediate exposure to stocked populations of Rainbow Trout (Oncorhync...

Effect of divergence in residual feed intake on expression of lipid metabolism-related genes in the liver of meat-type ducks.

Lipid metabolism is considered one of the important factors affecting residual feed intake (RFI). However, the relationship between RFI and expression of lipid metabolism-related genes is unknown in meat-type ducks. To address this issue, a total of 1,000 male meat-type ducks with similar body weight were randomly selected to measure body weight gain and feed intake from 21 to 42 days of age to estimate RFI. The eight greatest- (high RFI) and lowest- (Low RFI) ranking birds were then selected for the presen...

Effects of dry-season irrigation on leaf physiology and biomass allocation in tropical lianas and trees.

Lianas are more abundant in seasonal forests than in wetter forests and are thought to perform better than trees when light is abundant and water is limited. We tested the hypothesis that lianas perform better than trees during seasonal drought using a common garden experiment with 12 taxonomically diverse species (6 liana and 6 tree species) in 12 replicated plots. We irrigated six of the plots during the dry season for four years, while the remaining 6 control plots received only ambient rainfall. In year...

Biotechnological mechanism for improving plant remobilization of phosphorus during leaf senescence.

Phosphorus enrichment of aquatic ecosystems through diffuse source pollution is an on-going issue worldwide. A potential solution lies in the use of fast-growing, multi-purpose feedstocks, such as trees, to limit the flow of phosphorus into riparian areas through luxury consumption. However, the perennial nature of trees and their use of leaves as storage organs for excess phosphorus may reduce the effectiveness of contaminant removal during periods of leaf abscission. In an attempt to improve phosphorus re...

Integrating three comprehensive datasets shows that mitochondrial DNA variation is linked to species traits and paleogeographic events in European butterflies.

Understanding the dynamics of biodiversity, including the spatial distribution of genetic diversity, is critical for predicting responses to environmental changes, as well as for effective conservation measures. This task requires tracking changes in biodiversity at large spatial scales and correlating with species functional traits. We provide three comprehensive resources to understand the determinants for mitochondrial DNA differentiation represented by i) 15,609 COI sequences and ii) 14 traits belonging...

Mayaro virus distribution in South America.

Mayaro virus (MAYV) is a pathogen endemic to South America and some Caribbean islands, with reports of occasional outbreaks. However, its current distribution and high-risk areas are little known. We conducted a modelling study to determine the areas with highest prevalence of MAYV occurrence in South America, based on confirmed cases and serological detection over the last 20 years and socio-environmental variables. We performed our analysis using Maxent software, a machine learning algorithm used for spec...

Endoplasmic reticulum stress: A master regulator of metabolic syndrome.

Endoplasmic reticulum (ER) stress, a change in the ER homeostasis, leads to initiation of the unfolded protein response (UPR). The primary functions of the UPR are to restore the ER's physiological activity and coordinate the apoptotic and adaptive responses. Pathophysiological conditions that augment ER stress include hypoxia, misfolded and/or mutated protein accumulation, and high glucose. Prolonged ER stress is a critical factor in the pathogenesis of metabolic syndrome including type 2 diabetes mellitus...

Metabolomics Analysis of Nutrient Metabolism in β-Cells.

The islets of Langerhans harbor multiple endocrine cell-types that continuously respond to circulating nutrient levels in order to adjust their secretion of catabolic and anabolic hormones. Stimulus-secretion coupling in these cells is largely of metabolic nature, i.e. metabolism of nutrient fuels yields signals that trigger and amplify secretion of hormones. Hence, metabolism in this micro-organ is in a major way in control of whole-body metabolism. Therefore, insights into islet metabolism is critical to ...

Role of infarct scar dimensions, border zone repolarization properties and anisotropy in the origin and maintenance of cardiac reentry.

Cardiac ventricular tachycardia (VT) is a life-threatening arrhythmia consisting of a well organized structure of reentrant electrical excitation pathways. Understanding the generation and maintenance of the reentrant mechanisms, which lead to the onset of VT induced by premature beats in presence of infarct scar, is one of the most important issues in current electrocardiology. We investigate, by means of numerical simulations, the role of infarct scar dimension, repolarization properties and anisotropic f...

Switching on the furnace: regulation of heat production in brown adipose tissue.

Endothermy requires a source of endogenous heat production. In birds, this is derived primarily from shivering, but in mammals it is mostly non-shivering thermogenesis (NST). Brown adipose tissue (BAT) is a specialized tissue found in Eutherian mammals that is the source of most NST. Heat production in BAT depends primarily on the activity of uncoupling protein 1 (UCP1), which decouples transport of protons across the inner mitochondrial membrane from synthesis of ATP. UCP1 and hence heat production of BAT ...

Cat flu: Broad spectrum polymeric antivirals.

Feline herpesvirus type 1 (FHV-1) and feline calicivirus (FCV) are considered as main causes of feline upper respiratory tract disease and the most common clinical manifestations include rhinotracheitis, conjunctivitis, and nasal/facial ulcerations. While the primary infection is relatively mild, secondary infections pose a threat to young or immunocompromised cats and may result in a fatal outcome. In this study, we made an effort to evaluate antiviral potency of poly(sodium 4-styrenesulfonates) (PSSNa) as...

Sites phosphorylated in human α-adrenoceptors in response to noradrenaline and phorbol myristate acetate.

Phosphorylation of the human α-adrenergic receptor (fused with the green fluorescent protein) was studied employing the inducible Flp-ln HEK293 T-Rex system for expression. Serine/alanine substitutions were performed in five sites corresponding to those previously identified as phosphorylation targets in the hamster ortholog. Desensitization was decreased in these mutants but receptor phosphorylation was still clearly detected. The protein phosphorylation of the wild-type receptor (fused to the green fluor...


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