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PubMed Journals Articles About "Apple Rollt Neues Apple Store Konzept Siri Smart" - Page: 20 RSS

15:34 EDT 14th August 2018 | BioPortfolio

Apple Rollt Neues Apple Store Konzept Siri Smart PubMed articles on BioPortfolio. Our PubMed references draw on over 21 million records from the medical literature. Here you can see the latest Apple Rollt Neues Apple Store Konzept Siri Smart articles that have been published worldwide.

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Showing "Apple rollt neues Apple Store Konzept Siri Smart" PubMed Articles 476–500 of 697

Rationalizing context-dependent performance of dynamic RNA regulatory devices.

The ability of RNA to sense, regulate and store information is an attractive attribute for a variety of functional applications including the development of regulatory control devices for synthetic biology. RNA folding and function is known to be highly context sensitive, which limits the modularity and reuse of RNA regulatory devices to control different heterologous sequences and genes. We explored the cause and effect of sequence context sensitivity for translational ON riboswitches located in the 5' UTR...


Stretchable Optomechanical Fiber Sensors for Pressure Determination in Compressive Medical Textiles.

Medical textiles are widely used to exert pressure on human tissues during treatment of post-surgical hematoma, burn-related wounds, chronic venous ulceration, and other maladies. However, the inability to dynamically sense and adjust the applied pressure often leads to suboptimal pressure application, prolonging treatment or resulting in poor patient outcomes. Here, a simple strategy for measuring sub-bandage pressure by integrating stretchable optomechanical fibers into elastic bandages is demonstrated. S...

Aptamer-based biosensors and nanosensors for the detection of vascular endothelial growth factor (VEGF): A review.

Vascular endothelial growth factor (VEGF) is a key regulator of vascular formation and a predominant protein biomarker in cancer angiogenesis. Owing to its crucial roles in the cancer metastasis, VEGF detection and quantification is of great importance in clinical diagnostics. Today, there exist a wide variety of detection strategies for identifying many types of disease biomarkers, especially for VEGF. As artificial single-stranded DNA or RNA oligonucleotides with catalytic and receptor properties, aptamer...


Stained Gels Can Be Stored for Several Months in Nonsealed Polyethylene Bags.

It is customary to dry gels (SDS-PAGE, native gels, or two-dimensional gels) after staining for record keeping purposes. This is typically carried out with gel dryers or by drying between two cellophane sheets held together by acrylic frames. Here, we report a simple method to store a variety of stained gels without any storage buffer within flexible nonsealed polyethylene bags. Gels can be stored for several months at room temperature without significant shrinking or protein diffusion. The gel stays hydrat...

A Temperature-Controlled, Conductive PANI@CNFs/MEOMA/PEGMA Hydrogel for Flexible Temperature Sensors.

Electrically conductive, yet stimuli-responsive hydrogels are highly desirable for many technological applications. However, the discontinuous conductivity of hydrogels during the response process has become a bottleneck that limits their application. To overcome this constraint, a linearly tunable, electrically conductive hydrogel is prepared using in-situ polymerized polyaniline (PANI) on a CNFs/MEOMA/PEGMA hydrogel (PANI@CMP hydrogel) substrate. The PANI@CMP hydrogel exhibits temperature-tunable electric...

Mash1-expressing cells could differentiate to type III cells in adult mouse taste buds.

The gustatory cells in taste buds have been identified as paraneuronal; they possess characteristics of both neuronal and epithelial cells. Like neurons, they form synapses, store and release transmitters, and are capable of generating an action potential. Like epithelial cells, taste cells have a limited life span and are regularly replaced throughout life. However, little is known about the molecular mechanisms that regulate taste cell genesis and differentiation. In the present study, to begin to underst...

Dynamic Coordination of Eu-Iminodiacetate to Control Fluorochromic Response of Polymer Hydrogels to Multistimuli.

New fluorochromic materials that reversibly change their emission properties in response to their environment are of interest for the development of sensors and light-emitting materials. A new design of Eu-containing polymer hydrogels showing fast self-healing and tunable fluorochromic properties in response to five different stimuli, including pH, temperature, metal ions, sonication, and force, is reported. The polymer hydrogels are fabricated using Eu-iminodiacetate (IDA) coordination in a hydrophilic pol...

A general framework for sensor-based human activity recognition.

Today's wearable devices like smartphones, smartwatches and intelligent glasses collect a large amount of data from their built-in sensors like accelerometers and gyroscopes. These data can be used to identify a person's current activity and in turn can be utilised for applications in the field of personal fitness assistants or elderly care. However, developing such systems is subject to certain restrictions: (i) since more and more new sensors will be available in the future, activity recognition systems s...

The ED-A domain enhances the capacity of fibronectin to store latent TGF-β binding protein-1 in the fibroblast matrix.

Dysregulated secretion and extracellular activation of TGF-β1 stimulates myofibroblasts to accumulate disordered and stiff extracellular matrix (ECM) in fibrosis. Fibronectin immobilizes latent TGF-β binding protein-1 (LTBP-1) and thus stores TGF-β1 in the ECM. Because the ED-A fibronectin splice variant is prominently expressed in fibrosis and supports myofibroblast activation, we investigated whether ED-A promotes LTBP-1-fibronectin interactions. Using stiffness-tuneable substrates for human dermal fib...

Characterization of a lipid droplet protein from Yarrowia lipolytica that is required for its oleaginous phenotype.

Oleaginous microorganisms are characterized by their ability to store high amounts of triacylglycerol (TAG) in intracellular lipid droplets (LDs). In this work, we characterized a protein of the oleaginous yeast Yarrowia lipolytica that is associated with LD and plays a role in the regulation of TAG storage. This protein is required for the oleaginous phenotype of Y. lipolytica because deletion of the coding gene results in a strongly reduced TAG content of the mutant. Therefore, we named it Oleaginicity In...

A starch-based stimuli-responsive magnetite nanohydrogel as de novo drug delivery system.

A novel starch-based stimuli-responsive magnetite nanohydrogel (MNHG), namely FeO-g-[poly(N-isopropylacrylamide-co-maleic anhydride)]@strach; FeO-g-(PNIPAAm-co-PMA)@starch, was successfully developed for targeted delivery of doxorubicin (DOX) as an anticancer drug. First, magnetite nanoparticles (MNPs) was modified using chloroacetyl chloride moiety followed by grafting of NIPAAm and MA monomers through ATRP technique. The resultant FeO-g-(PNIPAAm-co-PMA) nanocomposite was crosslinked through the reaction b...

Application of Computational Intelligence to Improve Education in Smart Cities.

According to UNESCO, education is a fundamental human right and every nation's citizens should be granted universal access with equal quality to it. Because this goal is yet to be achieved in most countries, in particular in the developing and underdeveloped countries, it is extremely important to find more effective ways to improve education. This paper presents a model based on the application of computational intelligence (data mining and data science) that leads to the development of the student's knowl...

A Review of Selective Laser Melted NiTi Shape Memory Alloy.

NiTi shape memory alloys (SMAs) have the best combination of properties among the different SMAs. However, the limitations of conventional manufacturing processes and the poor manufacturability of NiTi have critically limited its full potential applicability. Thus, additive manufacturing, commonly known as 3D printing, has the potential to be a solution in fabricating complex NiTi smart structures. Recently, a number of studies on Selective Laser Melting (SLM) of NiTi were conducted to explore the various a...

Phosphodiester models for cleavage of nucleic acids.

Nucleic acids that store and transfer biological information are polymeric diesters of phosphoric acid. Cleavage of the phosphodiester linkages by protein enzymes, nucleases, is one of the underlying biological processes. The remarkable catalytic efficiency of nucleases, together with the ability of ribonucleic acids to serve sometimes as nucleases, has made the cleavage of phosphodiesters a subject of intensive mechanistic studies. In addition to studies of nucleases by pH-rate dependency, X-ray crystallog...

Glyphosate residue concentrations in honey attributed through geospatial analysis to proximity of large-scale agriculture and transfer off-site by bees.

Honey taken directly from 59 bee hives on the Hawaiian island of Kaua'i was analyzed for glyphosate residue using ELISA techniques. Glyphosate residue was detected (> LOQ) in 27% of honey samples, at concentrations up to 342 ppb, with a mean = 118 ppb, S.E.M. 24 ppb. Of 15 honey samples store-purchased on Kaua'i, glyphosate was detected in 33%, with a mean concentration of 41 ppb, S.E.M. 14. Glyphosate residue was not detected in two samples from the island of Molokai but was in one of four samples from the...

3D Printed Organ Models with Physical Properties of Tissue and Integrated Sensors.

The design and development of novel methodologies and customized materials to fabricate patient-specific 3D printed organ models with integrated sensing capabilities could yield advances in smart surgical aids for preoperative planning and rehearsal. Here, we demonstrate 3D printed prostate models with physical properties of tissue and integrated soft electronic sensors using custom-formulated polymeric inks. The models show high quantitative fidelity in static and dynamic mechanical properties, optical cha...

Regulation of trichome development in tobacco by JcZFP8, a C2H2 zinc finger protein gene from Jatropha curcas L.

Trichomes are epidermal outgrowths of plant tissues that can secrete or store large quantities of secondary metabolites, which contribute to plant defense responses against stress. The use of bioengineering methods for regulating the development of trichomes and metabolism is a widely researched topic. In the present study, we demonstrate that JcZFP8, a C2H2 zinc finger protein gene from Jatropha curcas L., can regulate trichome development in transgenic tobacco. To understand the underlying mechanisms, we ...

pH-sensitive doxorubicin-conjugated prodrug micelles with charge-conversion for cancer therapy.

Intelligent drug delivery systems with prolonged circulation time, reduced drug leakage in blood, target site-triggered drug release and endosomal escape are attractive and ideal for malignant tumor therapy. Herein, doxorubicin (DOX)-conjugated smart polymeric micelles based on 4-carboxy benzaldehyde-grafted poly (L-lysine)-block-poly (methacryloyloxyethyl phosphorylcholine) (PLL(CB/DOX)-b-PMPC) copolymer are prepared. DOX and electronegative 4-carboxy benzaldehyde are conjugated to the PLL block via an imi...

Cause or compensation?-Altered neuronal Ca2+ handling in Huntington's disease.

Huntington's disease (HD) is a hereditary neurodegenerative disorder of typically middle-aged onset for which there is no disease-modifying treatment. Caudate and putamen medium-sized spiny projection neurons (SPNs) most severely degenerate in HD. However, it is unclear why mutant huntingtin protein (mHTT) is preferentially toxic to these neurons or why symptoms manifest only relatively late in life. mHTT interacts with numerous neuronal proteins. Likewise, multiple SPN cellular processes have been describe...

Phosphate toxicity and tumorigenesis.

In this brief opinion article, we briefly summarized evidence that cellular phosphate burden from phosphate toxicity is a pathophysiological determinant of cancer cell growth. Tumor cells express more phosphate cotransporters and store more inorganic phosphate than normal cells, and dysregulated phosphate homeostasis is associated with the genesis of various human tumors. High dietary phosphate consumption causes the growth of lung and skin tumors in experimental animal models. Experimental studies show tha...

Cell encapsulation: Overcoming barriers in cell transplantation in diabetes and beyond.

Cell-based therapy is emerging as a promising strategy for treating a wide range of human diseases, such as diabetes, blood disorders, acute liver failure, spinal cord injury, and several types of cancer. Pancreatic islets, blood cells, hepatocytes, and stem cells are among the many cell types currently used for this strategy. The encapsulation of these "therapeutic" cells is under intense investigation to not only prevent immune rejection but also provide a controlled and supportive environment so they can...

Toxic hazards of ammonia release and population vulnerability assessment using geographical information system.

Today, chemical industries manufacture, store and transport evermore hazardous substances and hence the risk of accidental releases of these chemicals can become more and more catastrophic in the context of increasing population and their requirements. The damage potential is proportional to the population characteristics of the location as well as various meteorological factors and geographical features. For the risk assessment of ammonia toxicity, the storage facility at Eloor industrial area is taken as ...

A Label-free Sandwich Imaging Ellipsometry Immunosensor for Serological Detection of Procalcitonin.

Analysis of trace low molecular weight (LMW) proteins in serum using the label-free imaging ellipsometry (IE) immunosensor is still a challenge due to the lack of an effective signal amplification strategy and the serious non-specific adsorption. Herein we have developed a sandwich strategy-mediated IE (SSIE) immunosensor to enable the immunodetection of LMW protein biomarkers in serum samples. We have firstly found that the weak binding affinity and the insufficient surface amount density of the ligand are...

Smart subsidies for catchment conservation in Malawi.

Conservation agriculture (CA) is a management paradigm in which soil is covered outside of cropping seasons, minimally disturbed, and recharged with nitrogen-fixing legumes. Finding effective ways to encourage CA is a centuries-old problem playing out acutely today in Sub-Saharan Africa. To better understand this issue, we have collected data on rural livelihoods and CA adoption during a two-year intervention in southern Malawi. The intervention evaluated rates of CA adoption under two different structures ...

Reduction-sensitive polymeric nanomedicines: An emerging multifunctional platform for targeted cancer therapy.

The development of smart delivery systems that are robust in circulation and quickly release drugs following selective internalization into target cancer cells is a key to precision cancer therapy. Interestingly, reduction-sensitive polymeric nanomedicines showing high plasma stability and triggered cytoplasmic drug release behavior have recently emerged as one of the most exciting platforms for targeted delivery of various anticancer drugs including small chemical drugs, proteins, and nucleic acids. In viv...


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