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Chief High Stakes Gambit Boost Funding Autumn Budget PubMed articles on BioPortfolio. Our PubMed references draw on over 21 million records from the medical literature. Here you can see the latest Chief High Stakes Gambit Boost Funding Autumn Budget articles that have been published worldwide.
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Mediterranean annual grasslands are species-diverse ecosystems of high economic and ecological value. CO and water fluxes in these grasslands are triggered by the first rains in autumn, after a long hot and dry summer. Climate change scenarios project altered rainfall patterns, such as prolonged dry season into the autumn, while simultaneously nitrogen (N) deposition is increasing globally. However, how these global change drivers will interact to affect Mediterranean grassland CO, water fluxes and producti...
This paper discusses the UK Government's public consultation into the NHS bursary and the response from the Nursing and Midwifery Council. A public consultation stipulated that the current arrangements for funding, by the State, were not to be considered for discussion. Instead, the consultation only appraised views that would lead to the successful introduction of student finance loans for NHS professional education. Testimonies from nurses, midwives and nursing students expressed concern that the new fund...
This study aimed to assess the feasibility to plan and deliver highly heterogeneous doses to symptomatic large tumors using volumetric modulated arc therapy (VMAT) and simultaneous integrated boost (SIB) during a short course palliative accelerated radiotherapy.
Risk aversion is well-known as a general and robust characteristic of people's decision making: people are less likely to gamble when they are unsure if they will obtain the expected value of the bet made. The "peanuts effect" is, however, an exception to this general rule. The "peanuts effect," which states that people are more willing to gamble when playing for "peanuts" (a small outcome), has been stably observed in the context of a small monetary stake. We conducted two types of experiments to verify wh...
Major emergencies are extreme team decision making environments. They are complex, dynamic, high-stakes and fast paced events, wherein successful resolution is contingent upon effective teamwork. Not only do emergency teams coordinate at the intrateam level (e.g., police team), but they are increasingly required to operate at the interteam level (e.g., police, fire and ambulance teams). This is in response to the desire for networked and cost-effective practice and due to the evolving nature of modern threa...
The theoretical landscape of health disparities research now emphasizes health inequities and the role that social determinants of health (SDOH) play in creating and perpetuating them. Whether National Institutes of Health (NIH) funding patterns reflect this theoretical shift is unknown.
Therapeutic vaccination is a promising strategy for controlling chronic hepatitis B virus (HBV). Here, we tested whether several novel vaccination strategies could be used to induce HBV-specific adaptive immune responses and control/eradicate HBV in a mouse model. Robust HBV antigen-specific antibody responses were elicited by several vaccination strategies using a novel particle vaccine (HBSS1), which expresses a fusion of the S (amino acids [aa] 1-223) and preS1 (aa 21-47) antigens, and/or a recombinant a...
The calculation of free energy differences between levels of theory has numerous potential pitfalls. Chief amongst them is the lack of overlap, i.e., ensembles generated at one level of theory (e.g., ``low'') not being good approximations of ensembles at the other (e.g., ``high''). Numerous strategies have been devised to mitigate this issue. However, the most straight-forward approach is to ensure that the ``low'' level ensemble more closely resembles that of the ``high''. Ideally, this is done without inc...
When writing up a grant application, the proposal has to be targeted to the funding source identified and being approached. However, some general rules apply in all cases. Provision of preliminary data may be useful and collaboration with well-known/published colleagues and top centres may also help and may be a prerequisite for some kinds of application. The quality and originality of the science is the main selling point as well as convincing the review board that you/your consortium are the best placed g...
Assess feasibility-rate of PCR, short-term toxicity after neoadjuvant concurrent chemoradiation (NACRT) delivered via simultaneous integrated boost (SIB) using volumetric modulated arc therapy (VMAT) technique for locally advanced rectal cancer.
and Purpose: To examine the feasibility of SBRT as an EBRT boost to PET positive Lymph Nodes (PET(+) LN) in cervical cancer patients and evaluate overall tumor control probability (TCP) increase.
To assess the budget impact to a US commercial health plan of providing access to the Flexitouch (FLX) advanced pneumatic compression device (Tactile Medical) to lymphedema (LE) patients with either comorbid chronic venous insufficiency (CVI) or frequent infections.
Studies of perceptual learning have revealed a great deal of plasticity in adult humans. In this study, we systematically investigated the effects and mechanisms of several forms (trial-by-trial, block, and session rewards) and levels (no, low, high, subliminal) of monetary reward on the rate, magnitude, and generalizability of perceptual learning. We found that high monetary reward can greatly promote the rate and boost the magnitude of learning and enhance performance in untrained spatial frequencies and ...
This article evaluates gender differences in academic rank and National Institutes of Health (NIH) funding among academic maternal-fetal medicine (MFM) physicians.
Survival of junior scientists in academic biomedical research is difficult in today's highly competitive funding climate. National Institute of Health (NIH) data on first-time R01 grantees indicate the rate at which early investigators drop out from a NIH-supported research career is most rapid 4 to 5 years from the first R01 award. The factors associated with a high risk of dropping out, and whether these factors impact all junior investigators equally, are unclear. We identified a cohort of 1,496 investig...
Upland forest soils are known to be the main biological sink for methane, but studies have shown that net methane uptake of a forest ecosystem can be reduced when methane emissions by vegetation are considered. We estimated the methane budget of a young oak plantation by considering tree stems but also the understorey vegetation. Automated chambers connected to a laser-based gas analyser, on tree stems, bare soil and soil covered with understorey vegetation, recorded CH fluxes for 7 months at 3 h interval...
Moral evaluations occur quickly following heuristic-like intuitive processes without effortful deliberation. There are several competing explanations for this. The ADC-model predicts that moral judgment consists in concurrent evaluations of three different intuitive components: the character of a person (Agent-component, A); their actions (Deed-component, D); and the consequences brought about in the situation (Consequences-component, C). Thereby, it explains the intuitive appeal of precepts from three domi...
Safety and tolerability of HIV-1 multiantigen pDNA vaccine given with IL-12 plasmid DNA via electroporation, boosted with a recombinant vesicular stomatitis virus HIV Gag vaccine in healthy volunteers in a randomized, controlled clinical trial.
The addition of plasmid cytokine adjuvants, electroporation, and live attenuated viral vectors may further optimize immune responses to DNA vaccines in heterologous prime-boost combinations. The objective of this study was to test the safety and tolerability of a novel prime-boost vaccine regimen incorporating these strategies with different doses of IL-12 plasmid DNA adjuvant.