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PubMed Journals Articles About "Cognitive Functional Therapy Compared To Cognitive Patient Education And Physiotherapy For Patients With Low Back Pain∨derfield=score∨derval=desc" - Page: 3 RSS

13:49 EDT 18th July 2019 | BioPortfolio

Cognitive Functional Therapy Compared To Cognitive Patient Education And Physiotherapy For Patients With Low Back Pain∨derfield=score∨derval=desc PubMed articles on BioPortfolio. Our PubMed references draw on over 21 million records from the medical literature. Here you can see the latest Cognitive Functional Therapy Compared To Cognitive Patient Education And Physiotherapy For Patients With Low Back Pain∨derfield=score∨derval=desc articles that have been published worldwide.

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Showing "Cognitive Functional Therapy Compared Cognitive Patient Education Physiotherapy" PubMed Articles 51–75 of 38,000+

Complementation of dopaminergic signaling by Pitx3-GDNF synergy induces dopamine secretion by multipotent Ntera2 cells.

Human teratocarcinoma cell line Ntera2 (NT2) expresses dopamine signals and has shown its safe profile for clinical applications. Attempts to restore complete dopaminergic (DAergic) phenotype enabling these cells to secrete dopamine have not been fully successful so far. We applied a blend of gene transfer techniques and a defined medium to convert NT2 cells to fully DAergic. The cells were primarily engineered to overexpress the Pitx3 gene product and then cultured in a growth medium supplemented with knoc...


ZnO Quantum Dots Coupled with Graphene toward Electrocatalytic N2 Reduction: Experimental and DFT Investigations.

Electrochemical reduction of N2 to NH3 offers a promising way for artificial N2 production, but requires the efficient and robust electrocatalysts to boost the N2 reduction reaction (NRR). Herein, a combination of experimental measurements and theoretical calculations revealed that the ZnO quantum dots (QDs) supported on reduced graphene oxide (ZnO/RGO) hybrid could be a highly active and stable catalyst for NRR at ambient conditions. Experimentally, the ZnO/RGO was confirmed to favor the N2 adsorption due ...

Two novel SSH1 mutations in Chinese patients with disseminated superficial actinic porokeratosis and Immunohistochemical analysis of Anti-Slingshot homolog 1 antibody in one typical patient.

Disseminated superficial actinic porokeratosis (DSAP) is the most common subtype of porokeratosis exhibiting an autosomal dominant mode. It is characterized by multiple small, annular, keratotic lesions that are located predominantly on sun-exposed areas of the skin .Up to now, six loci have been reported to be linked to DSAP .Beside the mutations in the mevalonate pathway genes MVK, PMVK, MVD and FDPS , mutations in SSH1, SART3 and SLC17A9 have also been suggested to be responsible for DSAP .However, it is...


Goosebumps-Inspired Microgel Patterns with Switchable Adhesion and Friction.

A substrate mimicking the surface topography and temperature sensitivity of skin goosebumps is fabricated. Close-packed arrays of thermoresponsive microgel particles undergo topographical changes in response to temperature changes between 25 and 37 °C, resembling the goosebump structure that human skin develops in response to temperature changes or other circumstances. Specifically, positively charged poly[2-(methacryloyloxy)ethyltrimethylammonium chloride] (PMETAC) brushes serve as an anchoring substrate ...

Modelling the impact of liana infestation on the demography and carbon cycle of tropical forests.

There is mounting empirical evidence that lianas affect the carbon cycle of tropical forests. However, no single vegetation model takes into account this growth form, although such efforts could greatly improve the predictions of carbon dynamics in tropical forests. In this study, we incorporated a novel mechanistic representation of lianas in a dynamic global vegetation model (the Ecosystem Demography Model). We developed a liana-specific plant functional type and mechanisms representing liana-tree interac...

Changes in presynaptic calcium signalling accompany age-related deficits in hippocampal LTP and cognitive impairment.

The loss of cognitive function accompanying healthy aging is not associated with extensive or characteristic patterns of cell death, suggesting it is caused by more subtle changes in synaptic properties. In the hippocampal CA1 region, long-term potentiation requires stronger stimulation for induction in aged rats and mice and long-term depression becomes more prevalent. An age-dependent impairment of postsynaptic calcium homeostasis may underpin these effects. We have examined changes in presynaptic calcium...

New designs for phototherapeutic transition metal complexes.

In this minireview, we highlight recent advances in the design of transition metal complexes for photodynamic therapy (PDT) and photoactivated chemotherapy (PACT), and discuss the challenges and opportunities for the translation of such agents into clinical use. New designs for light-activated transition metal complexes offer photoactivatable prodrugs with novel targeted mechanisms of action. Light irradiation can achieve spatial and temporal control of drug activation, increasing selectivity and reducing s...

Exposing {001} Crystal Plane on Hexagonal Ni-MOF with Surface-Grown Cross-Linked Mesh-Structures for Electrochemical Energy Storage.

Hexagonal nickel-organic framework (Ni-MOF) [Ni(NO ) ·6H O, 1,3,5-benzenetricarboxylic acid, 4-4'-bipyridine] is fabricated through a one-step solvothermal method. The {001} crystal plane is exposed to the largest hexagonal surface, which is an ideal structure for electron transport and ion diffusion. Compared with the surrounding rectangular crystal surface, the ion diffusion length through the {001} crystal plane is the shortest. In addition, the cross-linked porous mesh structures growing on the {001} c...

Adaptive functional reorganisation in amyotrophic lateral sclerosis: coexisting degenerative and compensatory changes.

Considerable functional reorganisation takes place in amyotrophic lateral sclerosis in face of relentless structural degeneration. This study evaluates functional adaptation in ALS patients with lower motor neuron (LMNp) and upper motor neuron predominant (UMNp) dysfunction.

Polymeric Micelles Loading Proteins through Concurrent Ion Complexation and pH-Cleavable Covalent Bonding for In Vivo Delivery.

Protein drugs have great potential as targeted therapies, yet their application suffers from several drawbacks, such as instability, short half-life, and adverse immune responses. Thus, protein delivery approaches based on stimuli-responsive nanocarriers can provide effective strategies for selectively enhancing the availability and activation of proteins in targeted tissues. Herein, polymeric micelles with the ability of encapsulating proteins are developed via concurrent ion complexation and pH-cleavable ...

Impact of Prosthesis-Patient Mismatch on 1-Year Outcomes after Transcatheter Aortic Valve Implantation: Meta-analysis of 71,106 Patients.

This study sought to evaluate the impact of prosthesis-patient mismatch (PPM) on the risk of early-term mortality after transcatheter aortic valve implantation (TAVI).

Acute Kidney Injury after Cardiac Surgery: Risk Factors and Novel Biomarkers.

Acute kidney injury (AKI) is a common and severe complication after cardiac surgery. Currently, a series of novel biomarkers have favored the assessment of AKI after cardiac surgery in addition to the conventional indicators. The biomartkers, such as urinary liver fatty acid binding protein (L-FABP), urinary neutrophil gelatinase-associated lipocalin (NGAL), serum L-FABP, heart-type FABP, kidney injury molecule 1 (KIM-1), and interleukin-18 were found to be significantly higher in patients who developed AKI...

Prosthesis-Patient Mismatch after Surgical Aortic Valve Replacement: Neither Uncommon nor Harmless.

Prosthesis-patient mismatch (PPM) after surgical aortic valve replacement (SAVR) is an issue that has been overlooked (not to say neglected). Cardiac surgeons must bear in mind that this is a real problem that we must tackle. The purpose of this paper is to be a wake-up call to the surgical community by giving a brief overview of what PPM is, its incidence and impact on the outcomes. We also discuss the increasing role played by imaging for predicting and assessing PPM after SAVR (with which surgeons must b...

The Bridge Occlusion Balloon for Venous Angioplasty in Superior Vena Cava Occlusion.

The Bridge Occlusion Balloon is a compliant balloon, specifically designed for temporary Superior vena cava occlusion in case of Superior Vena Cava laceration during lead extraction procedures. We here report the first case, using Bridge Occlusion Ballon for a venous angioplasty in a patient with dysfunctional pacemaker leads and symptomatic Superior Vena Cava occlusion. After successful lead extraction, venography was showing a narrow venous canal. Therefore, venous angioplasty using the Bridge balloon was...

Rapidly Progressive Malignant Fibrous Histiocytoma of Right Atrium: a Rare Case Report.

We are going to present a case of malignant fibrous histiocytoma in the right atrium, which is a very rare entity. The patient had a right atrial mass, which prolapsed through the tricuspid valve into the right ventricle, causing functional tricuspid valve stenosis. The tumor was completely resected and the patient had an uneventful postoperative period. Histopathological examination reported malignant fibrous histiocytoma. The patient presented to the emergency department five weeks after discharge with dy...

Mussel-Inspired pH-Switched Assembly of Capsules with Ultrathin and Robust Nanoshell.

Enclosed films, also called capsules, bearing an ultrathin and robust nanoshell have sparked numerous interests for use in many applications, for which facile preparation methods are urgently pursued. Inspired by the pH-programmed adhesion/cohesion of mussel-secreted foot proteins, polyphenol/polyamine capsules with an ultrathin and robust nanoshell are fabricated through a pH-switched assembly on sacrificial calcium carbonate (CaCO3) templates. Polyphenols adhere to the templates at pH 6.0 and rapidly cohe...

Four-Mode Programmable Metamaterial using Ternary Foldable Origami.

Designing multifunctional metamaterial with programmable feature has become a new trend in mechanical, acoustic, and electromagnetic research fields due to controllability of their structural behaviors and functionalities. The codable or reconfigurable structures have shown more remarkable characteristics than the traditional and conventional metamaterials to implement functional programmability. However, structural complexity and hi-tech requirement are the biggest constraints to their practical applicatio...

Enzyme-Activable Interferon-Poly(α-amino acid) Conjugates for Tumor Microenvironment Potentiation.

Protein-polymer conjugation is a clinically validated approach to enhanced pharmacokinetic properties. However, the permanent attachment of polymers often leads to irreversibly reduced protein bioactivity and poor tissue penetration. As such, the use of protein-polymer conjugates for solid tumors remains elusive. Herein, we report a simple strategy using enzyme-activable and size-shrinkable protein-polypeptide conjugates to overcome this clinical challenge. Briefly, a matrix metalloprotease (MMP)-responsive...

Tailoring the Chemical Modification of Chitosan Hydrogels to Fine Tune the Release of a Synergistic Combination of Chemotherapeutics.

Combination chemotherapy with defined ratio and sequence of drug release is a clinically established and effective route to treat advanced solid tumors. In this context, a growing body of literature demonstrates the potential of hydrogels constructed with chemically modified polysaccharides as depots for controlled release of chemotherapeutics. Identifying the appropriate modification in terms of physicochemical properties of the functional group and its degree of substitution (χ) to achieve the desired re...

Temperature Induced Self-Compensating Defect Traps and Gain Thresholds in Colloidal Quantum Dots.

Continuous-wave (CW) lasing was recently achieved in colloidal quantum dots (CQDs) by lowering the threshold through the introduction of biaxial strain. However, the CW laser threshold is still much higher than the femtosecond threshold. This must be addressed before electrically injected lasing can be realized. Here we investigate the relationship between threshold and temperature and find a sub-picosecond recombination process that proceeds very efficiently at temperatures reached during CW excitation. We...

Ruthenium(II)-Catalyzed C-H Acylmethylation between (Hetero)arenes and α-Cl Ketones/Sulfoxonium Ylides.

A first ruthenium(II)-catalyzed (hetero)arenes C-H activation coupling with α-Cl ketones/sulfoxonium ylides to efficiently generate acylmethylated (hetero)arenes has been described. Compared with the previous studies, this transformation constitutes the first coupling of α-Cl ketones with arenes under a low-cost Ru(II) complex catalysis. Meanwhile, sulfoxonium ylides function as the surrogates of α-Cl ketones were also used to yield acylmethylation of (hetero)arenes. This strategy features high efficienc...

A Supramolecular Strategy for Selective Catalytic Hydrogenation Independent of Remote Chain Length.

Performing selective transformations on complex substrates remains a challenge in synthetic chemistry. These difficulties often arise due to cross-reactivity, particularly in the presence of similar functional groups at multiple sites. Therefore, there is a premium on the ability to perform selective activation of these functional groups. We report here a supramolecular strategy where encapsulation of a hydrogenation catalyst enables selective olefin hydrogenation, even in the presence of multiple sites of ...

Converting SMILES to Stacking Interaction Energies.

Predicting the strength of stacking interactions involving heterocycles is vital for several fields, including structure-based drug design. While quantum chemical computations can provide accurate stacking interaction energies, these come at a steep computational cost. To address this challenge, we recently developed quantitative predictive models of stacking interactions between drug-like heterocycles and the aromatic amino acids Phe, Tyr, and Trp (DOI: 10.1021/jacs.9b00936). These models depend on heteroc...

Convolutional Neural Network of Atomic Surface structures to Predict Binding Energies For High-throughput Screening of Catalysts.

High-throughput screening of catalysts can be performed using density functional theory calculations to predict catalytic properties, often correlated with adsorbate binding energies. However, more complete investigations would require an order of 2 more calculations compared to the current approach, making the computational cost a bottleneck. Recently developed machine-learning methods have been demonstrated to predict these properties from hand-crafted features but have struggled to scale to large composi...

Iridium-Catalyzed Alkene-Selective Transfer Hydrogenation with 1,4-Dioxane as Hydrogen Donor.

The iridium-catalyzed transfer hydrogenation of alkenes using 1,4-dioxane as a hydrogen donor is described. The use of 1,2-bis(dicyclohexylphosphino)ethane (DCyPE), featuring bulky and highly electron-donating properties, led to high catalytic activity. A polystyrene-cross-linking bisphosphine PS-DPPBz produced a reusable heterogeneous catalyst. These homogeneous and heterogeneous protocols achieved chemoselective transfer hydrogenation of alkenes over other potentially reducible functional groups such as c...


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