Advertisement

Topics

PubMed Journals Articles About "Ganaxolone Phase Data Supports Progressing Phase Patients With" - Page: 3 RSS

01:25 EDT 24th September 2018 | BioPortfolio

Ganaxolone Phase Data Supports Progressing Phase Patients With PubMed articles on BioPortfolio. Our PubMed references draw on over 21 million records from the medical literature. Here you can see the latest Ganaxolone Phase Data Supports Progressing Phase Patients With articles that have been published worldwide.

More Information about "Ganaxolone Phase Data Supports Progressing Phase Patients With" on BioPortfolio

We have published hundreds of Ganaxolone Phase Data Supports Progressing Phase Patients With news stories on BioPortfolio along with dozens of Ganaxolone Phase Data Supports Progressing Phase Patients With Clinical Trials and PubMed Articles about Ganaxolone Phase Data Supports Progressing Phase Patients With for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Ganaxolone Phase Data Supports Progressing Phase Patients With Companies in our database. You can also find out about relevant Ganaxolone Phase Data Supports Progressing Phase Patients With Drugs and Medications on this site too.

Showing "Ganaxolone Phase Data Supports Progressing Phase Patients with" PubMed Articles 51–75 of 59,000+

P 128 - Influence of stance phase shifts in the movement analysis profile and the Gait Profile Score for cerebral palsy patients.

The Gait Profile Score (GPS) is used as a summary index to interpret gait abnormalities compared to a reference group, but stance phase shifts in gait cycles are not considered. The aim of this work is to point out, if stance phase shifts affects the GPS estimations and lead clinically relevant changes.


Assessing the pattern of recurrence in Danish stage I lung cancer patients in relation to the follow-up program: are we failing to identify patients with cerebral recurrence?

There is paucity of evidence regarding the optimal follow-up (FU) regimen for lung cancer. Consequently, FU is organized differently across countries. The Danish FU regimen has short FU intervals with a computed tomography (CT) scan of the chest and upper abdomen every three months in the early phase (first 2 years), then every six months in the late phase of FU (3rd, 5th year). Characterizing recurrences missed by the FU program in terms of site, tumor histology, department, and phase of FU, could improve ...

Menstrual cycle phase predicts women's hormonal responses to sexual stimuli.

A robust body of research has demonstrated shifts in women's sexual desire and arousal across the menstrual cycle, with heightened desire and arousal coincident with heightened probability of conception (POC), and it is likely that ovarian hormones modulate these shifts. However, studies in which women are exposed to audiovisual sexual stimuli (AVSS) at high POC (mid-follicular) and low POC (luteal) phases have failed to detect significant differences in genital or subjective arousal patterns based on menst...


Apalutamide: The established and emerging roles in the treatment of advanced prostate cancer.

Prostate cancer (PCa) is the most common cancer in elderly males. Androgen deprivation therapy (ADT) is still the cornerstone of initial treatment, however the vast majority of patients develop castration resistant prostate cancer (CRPC). Several studies with numerous androgen receptor (AR)-directed agents have emerged since the approval of abiraterone acetate and enzalutamide. One of these agents is apalutamide, which seems to be a promising AR antagonist for the treatment of CRPC. Areas covered: The autho...

A user's guide for phase separation assays with purified proteins.

The formation of membrane-less organelles and compartments by protein phase separation is an important way in which cells organize their cytoplasm and nucleoplasm. In vitro phase separation assays with purified proteins have become the standard way to investigate proteins that form membrane-less compartments. By now, various proteins have been purified and tested for their ability to phase separate and form liquid condensates in vitro. However, phase-separating proteins are often aggregation-prone and diffi...

Encoding and immediate retrieval tasks in patients with epilepsy: a functional MRI study of verbal and visual memory.

Medial lobe temporal structures and more specifically the hippocampus play a decisive role in episodic memory. Most of the memory functional magnetic resonance imaging (fMRI) studies evaluate the encoding phase; the retrieval phase being performed outside the MRI. We aimed to determine the ability to reveal greater hippocampal fMRI activations during retrieval phase.

Babinet-bilayered geometric phase optical elements.

Geometric phase optical elements based on structured anisotropy are widely used for phase shaping via their orientational degree of freedom. To date, amplitude shaping via space-variant retardance is much less investigated, a practical reason being that the spin-orbit interaction of light couples retardance with the dynamic part of the optical phase. Inspired by the complementary diffractive elements associated with Babinet's principle, a bilayered subwavelength grating design is proposed in order to cancel...

Interim Results of a Phase II Study of Hypofractionated Radiotherapy with Concurrent Temozolomide Followed by Adjuvant Temozolomide in Patients over 70 Years Old with Newly Diagnosed Glioblastoma.

In this phase II study, we investigate clinical outcomes and tolerability of hypofractionated radiotherapy (HRT) combined with temozolomide (TMZ) to treat elderly patients with glioblastoma (GBM).

Phase shift invariant imaging of coherent sources (PSIICOS) from MEG data.

Increasing evidence suggests that neuronal communication is a defining property of functionally specialized brain networks and that it is implemented through synchronization between population activities of distinct brain areas. The detection of long-range coupling in electroencephalography (EEG) and magentoencephalography (MEG) data using conventional metrics (such as coherence or phase-locking value) is by definition contaminated by spatial leakage. Methods such as imaginary coherence, phase-lag index or ...

Geriatric analysis from PRODIGE 20 randomized phase II trial evaluating bevacizumab + chemotherapy versus chemotherapy alone in older patients with untreated metastatic colorectal cancer.

Older patients have frailty characteristics that impair the transposition of treatment results found in younger patients. Predictive factors are needed to help with treatment choices for older patients. The PRODIGE 20 study is a randomized phase II study that evaluated chemotherapy associated with bevacizumab (BEV) or not (CT) in patients aged 75 years or older.

How to define pathologic pelvic floor descent in MR defecography during defecation?

To assess the extents of pelvic floor descent both during the maximal straining phase and the defecation phase in healthy volunteers and in patients with pelvic floor disorders, studied with MR defecography (MRD), and to define specific threshold values for pelvic floor descent during the defecation phase.

Simultaneous measurement of phase transmission and birefringence of an object under test.

This paper presents a novel interferometric method for the simultaneous spatially resolved analysis of an object under test regarding the phase transmission function and the magnitude and orientation of the (uniaxial) birefringence. The measurement strategy is based on variations of the phase and polarization and processing the interference patterns so obtained. With this method, which is very similar to the classical phase-shifting interferometry, a complete analysis of birefringent properties of the objec...

Addressing heterogeneity in the design of phase II clinical trials in geriatric oncology.

Cancer in the elderly is a major public issue. However, older patients have long been debarred from clinical trials. There is a high unmet medical need for specific trials addressing oncology strategies adapted to older patients' conditions. While randomised phase III trials remain the gold standard, they usually require large numbers of patients. In this perspective, late single-arm phase II trials assessing treatment feasibility might prove a good alternative. However, it is essential to take into account...

Interfacial coupling between noble metal nanoparticles and metal-organic frameworks for enhanced catalytic activity.

Metal-organic frameworks (MOFs) have great potential to become innovative heterogeneous supports for immobilizing catalytically active noble metal nanoparticles (NPs). However, unlike metal oxide supports, the interfacial interactions between noble metal NPs and MOFs are currently neglected, thus dramatically diminishing the advantage of MOFs as supports. Herein, ZIFs(Co/Zn)@M (M = Pd, Pt or Au) nanocomposites with well-defined interfaces are synthesized and used as catalysts in gas-phase CO oxidation and l...

Interlocking Kerr-microresonator frequency combs for microwave to optical synthesis.

We report accurate phase stabilization of an interlocking pair of Kerr-microresonator frequency combs. The two combs, one based on silicon nitride and one on silica, feature nearly harmonic repetition frequencies and can be generated with one laser. The silicon-nitride comb supports an ultrafast-laser regime with three-optical-cycle, 1-picosecond-period soliton pulses and a total dispersive-wave-enhanced bandwidth of 170 THz, while providing a stable phase-link between optical and microwave frequencies. We...

Thermal evolution of the crystal structure and phase transitions of KNbO.

The thermal evolution of the crystal structure and phase transitions of KNbO were investigated by high-temperature powder X-ray diffraction and Rietveld refinement of the diffraction data. Two phase transitions from orthorhombic (2) to tetragonal (4) and from tetragonal to cubic ( ) were confirmed, both on heating and cooling. Both phase transitions are first order based on the observed hysteresis. The mixed displacive and order-disorder nature of the tetragonal to cubic transition is argued based on symme...

The Phase diagram of symmetric electron-hole bilayer system : A variational Monte Carlo study.

We study the phase diagram of symmetric electron-hole bilayer at zero temperature and zero magnetic field within quantum Monte Carlo approach. Particularly, we conduct variational Monte Carlo simulation for various phases viz. paramagnetic fluid phase, ferromagnetic fluid phase, anti-ferromagnetic Wigner crystal phase, ferromagnetic Wigner crystal phase and excitonic phase to estimate the ground-state energy at different values of inlayer density and inter-layer spacing. The Slater-Jastrow style trial ...

Stent-assisted treatment of ruptured intracranial aneurysms in the acute phase: A single center experience.

The purpose of this study was to analyze the results of patients with ruptured aneurysms who were treated with a specific microstent in the acute phase of subarachnoid hemorrhage.

Incorporating public values into evaluative criteria: Using crowdsourcing to identify criteria and standards.

At its core, evaluation involves the generation of value judgments. These evaluative judgments are based on comparing an evaluand's performance to what the evaluand is supposed to do (criteria) and how well it is supposed to do it (standards). The aim of this four-phase study was to test whether criteria and standards can be set via crowdsourcing, a potentially cost- and time-effective approach to collecting public opinion data. In the first three phases, participants were presented with a program descripti...

Mixtures of Blue Phase Liquid Crystal with Simple Liquids: Elastic Emulsions and Cubic Fluid Cylinders.

We numerically investigate the behavior of a phase-separating mixture of a blue phase I liquid crystal with an isotropic fluid. The resulting morphology is primarily controlled by an inverse capillary number, χ, setting the balance between interfacial and elastic forces. When χ and the concentration of the isotropic component are both low, the blue phase disclination lattice templates a cubic array of fluid cylinders. For larger χ, the isotropic phase arranges primarily into liquid emulsion droplets whic...

Absolute sensitivity of phase measurement in an SU(1,1) type interferometer.

Absolute sensitivity is measured for the phase measurement in an SU(1,1) type interferometer, and the results are compared to that of a Mach-Zehnder interferometer operated under the condition of the same intra-interferometer intensity. The interferometer is phase locked to a point with the largest quantum noise cancellation, and a simulated phase modulation is added in one arm of the SU(1,1) interferometer. Both the signal and noise level are estimated at the same frequency range, and we obtained 3 dB imp...

Increasing Sexually Transmitted Infection Testing Through a Coordinated, Community-Wide Approach.

We describe the impact of the Adolescent Health Project on sexually transmitted infection (STI) testing in Omaha, NE, during phase 1 (media campaigns) and phase 2 (free STI testing). To assess the impact of each phase on STI testing, we examined monthly data from January 2013 to April 2017 via interrupted time series analyses. There was an immediate and statistically significant increase in testing during phase 2. Expanding and advertising free STI testing is a promising approach to increasing testing. (Am ...

Impact of acute phase depression on functional outcomes in stroke patients over 1 year.

This study examined the influence of acute phase post-stroke depression (PSD) on various functional outcomes over 1 year after stroke. PSD was diagnosed at 2 weeks after stroke using the Mini International Neuropsychiatric Interview and functional outcomes were assessed via the National Institutes of Health Stroke Scale, the Barthel Index, and the Mini-Mental State Examination at 2 weeks and 1 year. Acute phase PSD was an independent predictor of poor functional outcomes during both the acute and chronic ph...

An efficient phase error self-compensation algorithm for nonsinusoidal gating fringes in phase-shifting profilometry.

The phase-shifting method is widely used in fringe projection profilometry. Since both the digital light projector and camera used in a grating projection measurement system are nonlinear pieces of equipment, the grating fringes captured by using the camera do not have a good sinusoidal property, which leads to a three-dimensional measurement error. Although the double-step phase-shifting method has proved that the phase error can be reduced to a large extent, the number of grating fringes is doubled, which...

Phase Ib/II Study of Capmatinib (INC280) Plus Gefitinib After Failure of Endothelial Growth Factor Receptor (EGFR) Inhibitor Therapy in Patients With EGFR-Mutated, MET Factor-Dysregulated Non-Small-Cell Lung Cancer.

Purpose Mesenchymal-epithelial transition factor (MET) dysregulation occurs in up to 26% of non-small-cell lung cancers (NSCLCs) after epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor (TKI) treatment. Capmatinib (INC280) is a potent and selective MET inhibitor with preclinical activity in combination with gefitinib in EGFR-mutant, MET-amplified/overexpressing models of acquired EGFR-TKI resistance. This phase Ib/II study investigated the safety and efficacy of capmatinib plus gefitinib in p...


Advertisement
Quick Search
Advertisement
Advertisement