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PubMed Journals Articles About "Global Burden Musculoskeletal Diseases Rise∨derfield=score∨derval=desc" - Page: 3 RSS

13:28 EDT 18th July 2019 | BioPortfolio

Global Burden Musculoskeletal Diseases Rise∨derfield=score∨derval=desc PubMed articles on BioPortfolio. Our PubMed references draw on over 21 million records from the medical literature. Here you can see the latest Global Burden Musculoskeletal Diseases Rise∨derfield=score∨derval=desc articles that have been published worldwide.

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Showing "Global Burden Musculoskeletal Diseases Rise derfield score derval" PubMed Articles 51–75 of 21,000+

Association between abdominal aortic calcification, bone mineral density and fracture in older women.

Although a relationship between vascular disease and osteoporosis has been recognized, its clinical importance for fracture risk evaluation remains uncertain. Abdominal aortic calcification (AAC), a recognized measure of vascular disease detected on single-energy images performed for vertebral fracture assessment, may also identify increased osteoporosis risk. In a prospective 10-year study of 1,024 older predominantly Caucasian women (mean age 75.0±2.6 years) from the Perth Longitudinal Study of Aging coh...


Molecular docking studies of chloroquine and its derivatives against P23 domain of chikungunya virus: Implication in designing of novel therapeutic strategies.

The arthropod-transmitted chikungunya virus has emerged as an epidemic menace that causes debilitating polyarthritis. With this life-threatening impact on humans, the possible treatment requires to cure the viral infectivity. But, devoid of any vaccine against the chikungunya virus (CHIKV), there is a need to develop a novel chemotherapeutic strategy to treat this noxious infection. CHIKV carries highly compact P23 structure that possesses potential RNA-binding surface domains which extremely influences the...

Sex-specific efficacy and safety of cryoballoon versus radiofrequency ablation for atrial fibrillation: A systematic review and meta-analysis.

Atrial fibrillation (AF) is a growing healthcare burden, for which pulmonary vein isolation (PVI) using cryoballoon (CB) or radiofrequency (RF) represent attractive therapies. Women are at higher risk of recurrence after AF ablation and present a specific complications profile. Therefore, a systematic catheter-specific assessment of pulmonary vein isolation is urgently needed in women.


Codon usage of human hepatitis C virus clearance genes in relation to its expression.

Hepatitis C virus (HCV) infection is among the leading causes of hepatocellular carcinoma and liver cirrhosis globally, with a high economic burden. The disease progression is well established, but less is known about the spontaneous HCV infection clearance. This study tries to establish the relationship between codon biasness and expression of HCV clearance candidate genes in normal and HCV infected liver tissues. A total of 112 coding sequences comprising 151 679 codons were subjected to the computation...

19F-NMR Monitoring of Reversible Protein Post-Translational Modifications: Class D β-Lactamase Carbamylation and Inhibition.

Bacterial production of β-lactamases with carbapenemase activity is a global health threat. The active sites of class D carbapenemases such as OXA-48, which is of major clinical importance, uniquely contain a carbamylated lysine residue which is essential for catalysis. Although there is significant interest in characterizing this post-translational modification, and it is a promising inhibition target, protein carbamylation is challenging to monitor in solution. We report the use of 19F-NMR spectroscopy t...

Modelling the impact of liana infestation on the demography and carbon cycle of tropical forests.

There is mounting empirical evidence that lianas affect the carbon cycle of tropical forests. However, no single vegetation model takes into account this growth form, although such efforts could greatly improve the predictions of carbon dynamics in tropical forests. In this study, we incorporated a novel mechanistic representation of lianas in a dynamic global vegetation model (the Ecosystem Demography Model). We developed a liana-specific plant functional type and mechanisms representing liana-tree interac...

Climate change alters elevational phenology patterns of the European spruce bark beetle (Ips typographus).

The European spruce bark beetle Ips typographus is the most important insect pest in Central European forests. Under climate change, its phenology is presumed to be changing and mass infestations becoming more likely. While several studies have investigated climate effects across a latitudinal gradient, it remains an open question how phenology will change depending on elevation and topology. Knowing how an altered climate is likely to affect bark beetle populations, particularly across diverse topographies...

Dental deaths in Italy as reported by online press articles.

Mortality on the dental chair is a rare and underreported event. This study aimed to identify all deaths which occurred during dental procedures in Italy.

First Two Brazilian Cases: Correction of Ascending Aortic Aneurysm and Aortic Valve Stenosis with Sutureless/Rapid Deployment Aortic Prosthesis.

Ascending aortic aneurysm is usually associated with aortic valve diseases, especially aortic stenosis. The standard technique involves the substitution of the dilated aortic segment with a Dacron tube and replacement of the aortic valve with a regular prosthesis. The correction of ascending aortic aneurysm with aortic valve replacement using the new sutureless and rapid deployment prosthesis was performed by a minimally invasive approach and for the first time in a Brazilian Center.

The global repair profile of human alkyladenine DNA glycosylase on nucleosomes reveals DNA packaging effects.

Alkyladenine DNA glycosylase (AAG) is the only known human glycosylase capable of excising alkylated purines from DNA, including the highly mutagenic 1,N6-ethenoadenine (εA) lesion. Here we examine AAG's ability to excise εA from a nucleosome core particle (NCP), which is the primary repeating unit of DNA packaging in eukaryotes. Using chemical synthesis techniques, we assembled a global population of NCPs in which A is replaced with εA. While each NCP contains no more than one εA lesion, the total popu...

Mössbauerite as Iron-Only Layered Oxyhydroxide Catalyst for WO Photoanodes.

Mössbauerite, a trivalent iron-only layered oxyhydroxide, has been recently identified as an electrocatalyst for water oxidation. We investigated the material as potential cocatalyst for photoelectrochemical water oxidation on semiconductor photoanodes. The band edge positions of mössbauerite were determined for the first time with a combination of Mott-Schottky analysis and UV-vis diffuse reflectance spectroscopy. The positive value of the Mott-Schottky slope and the flatband potential of 0.34 V vs rever...

Prevalence and Distribution of Human Papillomavirus Genotypes Among Women in Kinshasa, The Democratic Republic of the Congo.

Cervical cancer is the leading cause of mortality by cancer in sub-Saharan Africa. The human papillomavirus (HPV) infection is recognized as a necessary and sufficient cause for cervical cancer. Population-specific estimates of HPV prevalence in the Democratic Republic of the Congo (DRC) are unknown. This study aims to estimate the prevalence of HPV and identify predominant genotypes circulating in Kinshasa, DRC.

Oncotype DX: Where Does It Stand in India?

Retrospective Cohort Study of Lassa Fever in Pregnancy, Southern Nigeria.

Clinical and histopathologic features of canine tegumentary leishmaniasis and the molecular characterization of Leishmania braziliensis in dogs.

Cutaneous leishmaniasis (CL), caused by Leishmania braziliensis, is the most important presentation of tegumentary leishmaniasis (TL) in Latin American. While the role of dogs as reservoirs of Leishmania infantum, and the clinic features of canine visceral leishmanisis are well described, little is known about the importance of dogs in the transmission of L. braziliensis to humans. In the present study, we determine the frequency of L. braziliensis infection in dogs with cutaneous and mucosal ulcers in an e...

Correction: Anti-leishmanial activity of Brevinin 2R and its Lauric acid conjugate type against L. major: In vitro mechanism of actions and in vivo treatment potentials.

[This corrects the article DOI: 10.1371/journal.pntd.0007217.].

Optimization and evaluation of the Esperanza Window Trap to reduce biting rates of Simulium damnosum sensu lato in Northern Uganda.

Onchocerciasis, or river blindness, has historically been an important cause of blindness, skin disease and economic disruption in Africa and the Americas. It is caused by the filarial parasite Onchocerca volvulus, which is transmitted by black flies in the genus Simulium. Over the past decade, several international programs have been formed to control, or more recently eliminate onchocerciasis, using mass drug administration (MDA) of ivermectin. However, in many areas of Africa (particularly those which ar...

Clinical indicators and coronary angiographic features of expansive arterial remodelling in patients with abdominal aortic aneurysms.

The co-existence of expansive arterial remodelling in both coronary arteries (CAs) and the abdominal aorta has already been reported, although the clinical indicators and quantitative analysis have not been well studied. We therefore aimed to clarify the clinical and anatomical characteristics of patients with abdominal aortic aneurysms (AAAs). 123 AAA patients who underwent coronary angiography were compared to 123 control patients selected by propensity score matching. CA diameters of all 3 vessels were m...

Changes in cecal microbiota community of suckling piglets infected with porcine epidemic diarrhea virus.

Diarrhea, caused by porcine epidemic diarrhea virus (PEDV), is a catastrophic gastrointestinal disease among suckling piglets, with high infectivity, morbidity, and mortality, causing huge economic losses to the pig industry. In the present study, we investigated the different microbiota from the cecal mucosa and cecal contents between healthy and PEDV-infected piglets. High-throughput 16S rRNA gene sequencing was performed to explore differences. The results revealed that microbial dysbiosis by PEDV infect...

Getting to intent: Are social norms influencing intentions to use modern contraception in the DRC?

Meeting the reproductive health needs of women in post-conflict settings is a global health priority. In the Democratic Republic of the Congo, social norms perpetuate gender-based violence and contribute to low contraceptive use and high fertility. The Masculinité, Famille, et Foi (MFF) intervention is working with communities in Kinshasa to create normative environments supportive of modern contraception access and use. Our analysis uses survey data collected from 900 men and women in 17 community groups ...

Eosinophil granule major basic protein 1 deposition in eosinophilic esophagitis correlates with symptoms independent of eosinophil counts.

In patients with eosinophilic esophagitis (EoE), symptoms often do not correlate with peak eosinophil counts (PEC) determined on histopathological examination of biopsy specimens. This may be because eosinophils degranulate during active disease and lose their morphological identity as intact cells and, therefore, are not enumerated on microscopic examination. Eosinophil granule proteins that are released into tissues with degranulation, including major basic protein 1 (eMBP1), likely contribute to disease ...

Neighborhood effects explain increasing asynchronous seedling survival in a subtropical forest.

Biotic interactions play a critical role in mediating community responses to temporal environmental variation, but the importance of these effects relative to the direct effects of environmental change remains poorly understood, particularly in diverse forest communities. Here we combine a neighborhood modeling approach with insights from coexistence theory to assess the effects of temporal variation in species interactions and environmental conditions (e.g., precipitation, temperature and understory light ...

Rain downpours affect survival and development of insect herbivores: the specter of climate change?

Changes in the frequency, duration and intensity of rainfall events are among the abiotic effects predicted under anthropogenic global warming. Heavy downpours may profoundly affect the development and survival of small organisms such as insects. Here, we examined direct (physically on the insects) and indirect (plant-mediated) effects of simulated downpours on the performance of caterpillars of two lepidopteran herbivores (Plutella xylostella and Pieris brassicae) feeding on black mustard (Brassica nigra) ...

Largely underestimated carbon emission from land use and land cover change in the conterminous US.

Carbon (C) emission from land use and land cover change (LULCC) is the most uncertain term in the global carbon budget primarily due to limited LULCC data and inadequate model capability (e.g., under-represented agricultural managements). We take the commonly used FAOSTAT-based global Land Use Harmonization data (LUH2) and a new high-resolution multi-source harmonized national LULCC database (YLmap) to drive a land ecosystem model (DLEM) in the conterminous US. We found that recent cropland abandonment and ...

Estimating aboveground net biomass change for tropical and subtropical forests: refinement of IPCC default rates using forest plot data.

As countries advance in greenhouse gas (GHG) accounting for climate change mitigation, consistent estimates of aboveground net biomass change (∆AGB) are needed. Countries with limited forest monitoring capabilities in the tropics and subtropics rely on IPCC 2006 default ∆AGB rates, which are values per ecological zone, per continent. Similarly, research on forest biomass change at large scale also make use of these rates. IPCC 2006 default rates come from a handful of studies, provide no uncertainty ind...


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