PubMed Journals Articles About "Diet/Growth Factor Mechanisms Of Gut Adaptation" - Page: 4 RSS

06:13 EST 23rd January 2019 | BioPortfolio

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Showing "Diet Growth Factor Mechanisms Adaptation" PubMed Articles 76–100 of 31,000+

The potential application of Concentrated Growth Factor in regenerative endodontics.

To investigate the potential application of concentrated growth factor (CGF) to promote pulp regeneration of immature teeth.

Effects of dietary yeast culture on growth performance, immune response and disease resistance of gibel carp (Carassius auratus gibelio CAS Ⅲ).

A 50-day feeding trial was carried out to evaluate the partial replacement of fishmeal by yeast culture (YC) on growth performance, immune response and resistance against Aeromonas hydrophila in gibel carp CAS Ⅲ (Carassius auratus gibelio). Four isonitrogenous and isoenergetic practical diets including a basal diet (the control diet containing 10% fish meal, D0) and three yeast culture diets (substituting 20%, 40%, 60% of the fishmeal in the basal diet, D20, D40 and D60, respectively) were formulated. Eac...

Effects of Bacillus subtilis and zinc on the growth performance, internal organ development, and intestinal morphology of male broilers with or without subclinical coccidia challenge.

Effects of antibiotic (bacitracin), anticoccidial (narasin), and alternative (Bacillus subtilis and zinc) feed additives on growth performance, internal organ development, and intestinal morphology of commercial broilers with or without subclinical coccidia challenge were determined. A total of 1,344 1-day-old male Ross × Ross 708 broilers were randomly distributed into 12 treatments (6 diets × 2 challenge treatments, 8 replication pens/treatment) in 96 floor pens. The 6 dietary treatments were as follows...

Fibroblast Growth Factor 9 Suppresses Striatal Cell Death Dominantly Through ERK Signaling in Huntington's Disease.

Huntington's disease (HD) is a heritable neurodegenerative disorder, and there is no cure for HD to date. A type of fibroblast growth factor (FGF), FGF9, has been reported to play prosurvival roles in other neurodegenerative diseases, such as Parkinson's disease and Alzheimer's disease. However, the effects of FGF9 on HD is still unknown. With many similarities in the cellular and pathological mechanisms that eventually cause cell death in neurodegenerative diseases, we hypothesize that FGF9 might provide n...

Overexpression of transforming growth factor β induced factor homeobox 1 represses NPC1L1 and lowers markers of intestinal cholesterol absorption.

Transforming growth factor β induced factor homeobox 1 (TGIF1) is a transcriptional repressor that limits the response to transforming growth factor ß signaling and also represses transcription independent of this pathway. Recently, we found higher serum cholesterol levels and more hepatic lipid accumulation in mice lacking Tgif1, and showed that TGIF1 can repress the expression of Soat2, the gene encoding the cholesterol esterifying enzyme acyl-Coenzyme A:cholesterol acyltransferase 2. Although there is ...

The Effect of Creep Feed intake and Starter Diet allowance on Piglets' Gut Structure and Growth Performance after Weaning.

Diets offered to lactating and weaned piglets are the most expensive diets within pig production; however, the effect of these diets on lifetime pig performance is inconsistent. The objective of the current study was to investigate the impact of creep feed consumption during lactation and different starter diet allowances on piglets' gut structure and lifetime growth performance. In total, 320 pigs and 80 pigs (Landrace × Large white) were used after weaning in a 2 × 2 factorial arrangement to study growt...

High-fat diet disrupts bone remodeling by inducing local and systemic alterations.

A high-fat (HF) diet leads to detrimental effects on alveolar bone (AB); however, the mechanisms linking adiposity to bone loss are poorly understood. This study investigated if AB resorption induced by an HF diet is associated with the regulation of inflammatory gene expression and if adipocytes can directly interfere with osteoclastogenesis. We also evaluated the effects of diet restriction (DR) on bone phenotype. C57BL6/J mice were fed normal chow or an HF diet for 12 weeks. Samples of maxillae, femur, b...

Effects of dietary taurine on growth, non-specific immunity, anti-oxidative properties and gut immunity in the Chinese mitten crab Eriocheir sinensis.

Taurine has been widely researched as a growth-promoting additive or as an antioxidant in aquatic animals because of its multiple functions, however, few studies have explored its effects on crustacean in spite of the occurrence of serious diseases. We studied the effects of taurine supplementation on the growth, non-specific immunity, anti-oxidative properties and gut immunity of the Chinese mitten crab Eriocheir sinensis. Healthy crabs (8.0 ± 0.5 g) were fed diets supplemented with taurine at 0% (c...

Aldehyde Dehydrogenase-2 Attenuates Myocardial Remodeling and Contractile Dysfunction Induced by a High-Fat Diet.

Consumption of a high-fat (HF) diet exacerbates metabolic cardiomyopathy through lipotoxic mechanisms. In this study, we explored the role of aldehyde dehydrogenase-2 (ALDH2) in myocardial damage induced by a HF diet.

Insulin-like growth factor-I is inversely associated with liver fibrotic markers in patients with type 2 diabetes mellitus.

Insulin-like growth factor-I regulates mitochondrial function, oxidative stress, inflammation, stellate cells, and insulin sensitivity in the liver, and it might be associated with liver fibrosis from non-alcoholic steatohepatitis (NASH). On the other hand, type 2 diabetes mellitus (T2DM) is closely associated with the progression from non-alcoholic fatty liver to NASH and cirrhosis, so careful evaluation of liver fibrosis is required in patients with T2DM. Therefore, we examined the relationship between in...

Effects of concentrated growth factors on the angiogenic properties of dental pulp cells and endothelial cells: an in vitro study.

The aim was to investigate the angiogenic effects of concentrated growth factors on human dental pulp cells and human umbilical vein endothelial cells. Cells were treated with concentrated growth factor extracts. The CCK-8 assay and cell cycle assay were conducted to evaluate cell growth. Cell migration was evaluated by the Transwell migration assay. Angiogenesis-associated mRNA and protein expression levels were determined using quantitative real-time PCR and Western blotting, respectively. A tube formatio...

Effects of chromium picolinate supplementation on growth, body composition, and biochemical parameters in Nile tilapia Oreochromis niloticus.

A feeding trial was conducted to evaluate the effects of chromium picolinate (Cr-Pic) on growth performance, body composition, and biochemical parameters in Nile tilapia Oreochromis niloticus. Five experimental diets were formulated with high-protein diet (HP), low-protein diet (LP), and LP + 0.6, 1.2, or 1.8 mg kg Cr, respectively. Each diet was randomly assigned to four replicate groups of 30 fish per aquarium in a water-circulated rearing system for 60 days. Dietary 1.2 or 1.8 mg kg Cr inclusion sig...

De Novo assembly and comparative transcriptome analyses of purple and green morphs of Apostichopus japonicus during body wall pigmentation process.

Pigmentation processes provide a traceable and relevant trait for understanding key issues in evolutionary biology such as adaptation, speciation and the maintenance of balanced polymorphisms. The sea cucumber Apostichopus japonicus, which has nutritive and medical properties, is considered the most valuable commercial species in many parts of Asia. Compared with the green morph, the purple morph is rare and has great appeal to consumers. However, little is currently known about the molecular mechanism of b...

Insulin-like growth factor type I selectively binds to G-quadruplex structures.

G-quadruplex has been viewed as a promising therapeutic target in oncology due to its potentially important roles in physiological and pathological processes. Emerging evidence suggests that the biological functions of G-quadruplexes are closely related to the binding of some proteins. Insulin-like growth factor type I (IGF-1), as a significant modulator of cell growth and development, may serve as a quadruplex-binding protein.

Expression of insulin-like growth factor I and its receptor in the liver of children with biopsy-proven NAFLD.

Nonalcoholic fatty liver disease is one of the major complications of obesity, occurring already in pediatric age. Insulin like growth factor-I has been proposed as a potential therapeutic agent for its beneficial effect in experimental liver fibrosis. The aim of this work was to investigate the expression of insulin-like growth factor-I and its receptor in the liver of children with biopsy-proven nonalcoholic fatty liver disease and relate it to liver histological features.

Farm-Level Agricultural Biodiversity in the Peruvian Andes Is Associated with Greater Odds of Women Achieving a Minimally Diverse and Micronutrient Adequate Diet.

The extent to and mechanisms by which agricultural biodiversity may influence diet diversity and quality among women are not well understood.

Protective efficacy of Shilajit enriched diet on growth performance and immune resistance against Aeromonas hydrophila in Oreochromis mossambicus.

We investigated the effects of dietary enriched with Shilajit in three dose levels: 2.0, 4.0, and 6.0 g kg in the basal diet on growth rate, non-specific immune response, and disease resistance for 60 days in Oreochromis mossambicus against an opportunist pathogen, Aeromonas hydrophila. The results showed that the Shilajit enriched diets at 4.0 and 6.0 g kg diets significantly (p 

Differential aging of growth plate cartilage underlies differences in bone length and thus helps determine skeletal proportions.

Bones at different anatomical locations vary dramatically in size. For example, human femurs are 20-fold longer than the phalanges in the fingers and toes. The mechanisms responsible for these size differences are poorly understood. Bone elongation occurs at the growth plates and advances rapidly in early life but then progressively slows due to a developmental program termed "growth plate senescence." This developmental program includes declines in cell proliferation and hypertrophy, depletion of cells in ...

Negative Correlation between Placental Growth Factor and Endocan-1 in Women with Preeclampsia.

 To analyze endocan-1, a biomarker of vascular endothelial related pathologies, and the placental growth factor (PlGF), an angiogenic factor and a placental dysfunction marker in patients with preeclampsia (PE).

Obesity-Activated Adipose-Derived Stromal Cells Promote Breast Cancer Growth and Invasion.

Obese women diagnosed with breast cancer have an increased risk for metastasis, and the underlying mechanisms are not well established. Within the mammary gland, adipose-derived stromal cells (ASCs) are heterogeneous cells with the capacity to differentiate into multiple mesenchymal lineages. To study the effects of obesity on ASCs, mice were fed a control diet (CD) or high-fat diet (HFD) to induce obesity, and ASCs were isolated from the mammary glands of lean and obese mice. We observed that obesity incre...

Fibroblast growth factor 21 and fructose dynamics in humans.

Fructose consumption is a risk factor for metabolic disease. We recently demonstrated that fibroblast growth factor 21 (FGF21), a metabolic hormone involved in lipid and glucose metabolism, is acutely stimulated in humans by 75 g oral fructose, with peak levels occurring 2 h after consumption. This study reports on the dose dependency and reproducibility of the FGF21 response to fructose.

Diet and Psychosis: A Scoping Review.

Schizophrenia spectrum disorders (SSD) represent a cluster of severe mental illnesses. Diet has been identified as a modifiable risk factor and opportunity for intervention in many physical illnesses and more recently in mental illnesses such as unipolar depression; however, no dietary guidelines exist for patients with SSD.

Epidermal growth factor and fibroblast growth factor-2 circulating levels in elderly with major depressive disorder.

Epidermal growth factor (EGF) and Fibroblast Growth Factor-2 (FGF-2) are growth factors involved neuronal growth and synaptic plasticity. These markers have been implicated in neuropsychiatric disorders, including major depression. However, no particular studies of EGF and FGF-2 have been conducted in older adults with major depressive disorder (MDD). In this study, we aim to investigate the plasma levels of EGF and FGF-2 in elderly with MDD. We included 89 older adults with MDD and 51 older (healthy contro...

Study of acupuncture combined with rat nerve growth factor on neurobehavioral ability of cerebral palsy infant rats and its brain tissue growth and metabolism associated proteins.

To study the effects of acupuncture combined with rat nerve growth factor (NGF) on the cerebral palsy infant rats and the proteins which associated with growth, apoptosis and metabolism.

Attenuation of aquaporin-3 and epidermal growth factor receptor expression and activation in systemic sclerosis dermal fibroblasts.

Impaired wound healing and skin dehydration are the mainstay of systemic sclerosis (SSc) cutaneous manifestations. Aquaporin-3 (AQP3) has a pivotal role in skin hydration and wound healing. Epidermal growth factor receptor (EGFR) activation is impaired in SSc fibroblasts. It is unclear whether AQP3 downregulation or epidermal growth factor (EGF) signaling are the primary points of dysregulation in SSc patients.

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