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PubMed Journals Articles About "Global Burden Musculoskeletal Diseases Rise∨derfield=score∨derval=desc" - Page: 4 RSS

02:44 EDT 19th July 2019 | BioPortfolio

Global Burden Musculoskeletal Diseases Rise∨derfield=score∨derval=desc PubMed articles on BioPortfolio. Our PubMed references draw on over 21 million records from the medical literature. Here you can see the latest Global Burden Musculoskeletal Diseases Rise∨derfield=score∨derval=desc articles that have been published worldwide.

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Showing "Global Burden Musculoskeletal Diseases Rise derfield score derval" PubMed Articles 76–100 of 21,000+

Inflammation within the Neurovascular Unit: Focus on Microglia for Stroke Injury and Recovery.

Neuroinflammation underlies the etiology of multiple neurodegenerative diseases and stroke. Our understanding of neuroinflammation has evolved in the last few years and major players have been identified. Microglia, the brain resident macrophages, are considered sentinels at the forefront of the neuroinflammatory response to different brain insults. Interestingly, microglia perform other physiological functions in addition to their role in neuroinflammation. Therefore, an updated approach in which modulatio...


Epigenetic regulation of bone remodeling by natural compounds.

Osteoporosis and osteopenia impact more than 54 million Americans, resulting in significant morbidity and mortality. Alterations in bone remodeling are the hallmarks for osteoporosis, and thus the development of novel treatments that will prevent or treat bone diseases would be clinically significant, and improve the quality of life for these patients. Bone remodeling involves the removal of old bone by osteoclasts and the formation of new bone by osteoblasts. This process is tightly coupled, and is essenti...

Topical Treatment of Cutaneous Leishmaniasis in Israel, Part 2.

Cutaneous leishmaniasis is the most common form of leishmaniasis with global incidence of about 1.5 million cases annually. The disease is endemic in Israel and caused by two types, leishmania major and leishmania tropica. The two types of cutaneous leishmaniasis in Israel are not life threatening, but the multiple skin lesions developed from the contaminated sand fly bites cause significant damage to the quality of life for a few months in patients with leishmania major and sometimes for more than a year i...


Review on alginate-based hydrogel bio-printing for application in tissue engineering.

The dawn of 3D printing in medicals has pinned the domain with hopes of vitality in many patients combating with multitude of diseases. Also entitled as Bio-printing, this is appertained to its sequential printing of precursor ink, embodying cells and polymer/composite, in predetermined trajectory. Precursor ink, in addition to cells, constitutes predominantly hydrogels ascribed to its biodegradability and mimic ability of body's anatomy and mechanical features, e.g. bones, etc. This review paper is devoted...

Overweight and Lonely? A Representative Study on Loneliness in Obese People and Its Determinants.

Obesity is associated with physical and medical restrictions and comorbidities, but it also entails psychosocial effects such as social isolation and feelings of rejection. The aim of this study was to investigate the link between loneliness and weight stigma in a large sample of obese individuals. Results were derived from a large representative sample (n = 1,000). The survey included the 3-item version of the UCLA loneliness scale, the Patient Health Questionnaire (PHQ-9) as well as the Weight Bias Intern...

Altruistic Behavior Depending on Opponents' Body Weight: An Experimental Approach.

Obesity is a worldwide public health issue, not only because it is associated with numerous comorbid diseases but also because of its impact on the social level. This study aims to investigate (a) whether altruistic behavior differs between people with obesity and people who are not obese, (b) altruistic behavior toward people who are obese, in particular, women who are obese, and (c) implicit and explicit attitudes toward people with obesity as predictors for divergent altruistic behavior.

Effects of Antibiotic Therapy in Primary Sclerosing Cholangitis with and without Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis.

The authors conducted a systematic review and meta-analysis to assess the effect of antibiotic therapy in primary sclerosing cholangitis (PSC). Effect of antibiotic therapy on Mayo PSC Risk Score (MRS), serum alkaline phosphatase (ALP), total serum bilirubin (TSB), and adverse events (AEs) rates were calculated and expressed as standardized difference of means or proportions. Five studies including 124 PSC patients who received antibiotics were included. Overall, antibiotic treatment was associated with a s...

Psychotherapeutic Video Consultations in Primary Care - Concept of the PROVIDE Intervention and Results on the Intent to Adopt in Psychotherapists.

Mental health conditions represent a significant burden to the individual as well as the society. Within the health care system, the general practitioner is the first and, in most cases, the only provider. Timely referral of patients to specialized care is often difficult due to several barriers, particularly in rural areas. These barriers comprise long waiting times, the rising prevalence of psychosomatic and somatopsychic comorbidity, immobility in the elderly and stigmatisation related to mental health c...

THERAPEUTIC DRUG MONITORING OF INFLIXIMAB IN SPONDYLOARTHRITIS. A REVIEW OF THE LITERATURE.

Available evidence indicates that a therapeutic drug monitoring (TDM) strategy leads to major cost savings related to the anti-tumour necrosis factor-α (TNF-α) therapy in both inflammatory bowel disease and rheumatoid arthritis (RA) patients , with no negative impact on efficacy. However, although the systematic use of TDM could potentially be beneficial and economically acceptable to drug dose optimization, it is not justifiable for all drugs. Infliximab (IFX) is a chimeric monoclonal immunoglobulin G1 (...

Fully Automated Identification of Skin Morphology in Raster-Scan Optoacoustic Mesoscopy using Artificial Intelligence.

Identification of morphological characteristics of skin lesions is of vital importance in diagnosing diseases with dermatological manifestations. This task is often performed manually or in an automated way based on intensity level. Recently, ultra-broadband raster-scan optoacoustic mesoscopy (UWB-RSOM) was developed to offer unique cross-sectional optical imaging of the skin. A machine learning (ML) approach is proposed here to enable, for the first time, automated identification of skin layers in UWB-RSOM...

Dark-Field Microwells toward High-Throughput Direct miRNA Sensing with Gold Nanoparticles.

MicroRNA (miRNA) is a class of short RNA that is emerging as an ideal biomarker, as its expression level has been found to correlate with different types of diseases including diabetes and cancer. The detection of miRNA is highly beneficial for early diagnostics and disease monitoring. However, miRNA sensing remains difficult because of its small size and low expression levels. Common techniques such as quantitative real-time polymerase chain reaction (qRT-PCR), hybridization and Northern blotting have bee...

Influence of Thiazole-modified Carbon Nitride Nanosheets with Feasible Electronic Properties on Inverted Perovskite Solar Cells.

Effective, solution processable designs of interfacial electron transporting layers (ETLs) or hole-blocking layers are promising tools in modern electronic devices, e.g. to improve performance, cost and stability of perovskite-based solar cells. Herein, we introduce a facile synthetic route of thiazole-modified carbon nitride with 1.5 nm thick nanosheets which can be processed to a homogeneous, metal-free ETL for inverted perovskite solar cells. We show that thiazole-modified carbon nitride enables electron...

Temperature Dependence of the Energy Transfer in LHCII Studied by Two-Dimensional Electronic Spectroscopy.

We measured two-dimensional electronic spectra of light-harvesting complex II (LHCII) at various temperatures (77, 110, 150, 230 and 295 K) under conditions free from singlet-singlet annihilation. We elucidated the temperature-dependent excitation energy transfer dynamics in the Chl a manifold of LHCII. Global analysis revealed that the dynamics can be summarized in distinct timescales from 200 fs up to 15 ps. Whilst the fastest dynamics with a decay time of ~0.2-0.3 ps are relatively temperature-independen...

Association between sensitization and allergic diseases in 7-years-old Korean children.

Sensitization is associated with the exacerbation, severity, and prognosis of allergic diseases in children OBJECTIVE: We characterized the association between sensitization patterns and allergic diseases.

Efficacy of Ultra-Early (<12 hours), Early (12-24 hours), and Late (>24-138.5 hours) Surgery with MRI-Confirmed Decompression in AIS grades A, B, and C Cervical Spinal Cord Injury.

In cervical traumatic spinal cord injury (TSCI), the therapeutic effect of timing of surgery on neurological recovery remains uncertain. Additionally, the relationship between extent of decompression, imaging biomarker evidence of injury severity, and outcome is incompletely understood. We investigated the effect of timing of decompression on long-term neurological outcome in patients with complete spinal cord decompression confirmed on postoperative MRI. AIS grade conversion was determined in 72 AIS grades...

An Investigation Into the Factor Structure of the Attitudes to Suicide Prevention Scale.

The aim of this study was to investigate the factor structure of the Attitudes to Suicide Prevention Scale (ASPS). The ASPS was distributed to all staff in a UK National Health Service Trust ( = 957). We conducted an exploratory factor analysis followed by a confirmatory factor analysis by splitting the data 60/40 into training and testing subsets. A multiple regression analysis was carried out to investigate whether the overall scale score varied as a function of professional role, age, and gender and whe...

Efficiency of human olfactory ensheathing cell transplantation into spinal cysts to improve mobility of the hind limbs.

The pathological processes developing after spinal cord injuries often lead to the formation of cysts. Existing surgical and medical methods are insufficient for the treatment of posttraumatic spinal cord cysts. One of the emerging tools is cell therapy. The olfactory ensheathing cells are perspective cells for the cell therapy. Here, we demonstrated that the human olfactory ensheathing cell transplantation is effective in experimental spinal cysts. For our experiments, we selected animals only at the inter...

Randomized Clinical Trial of a Clinical Decision Support Tool for Improving the Appropriateness Scores for Ordering Imaging Studies in Primary and Specialty Care Ambulatory Clinics.

The objective of our study was to evaluate whether the use of a clinical decision support (CDS) tool improved the appropriateness scores of orders for advanced imaging in clinical practice. We used a stepped-wedge, cluster randomized clinical trial to evaluate the effectiveness of a CDS tool in an integrated health care system. Clinicians entered structured indications for each CT and MRI order, and the indications were electronically scored against appropriateness criteria to assign an appropriateness sco...

Multidrug-Resistant Klebsiella pneumoniae ST307 in Traveler Returning from Puerto Rico to Dominican Republic.

We report bla-harboring carbapenem-resistant Klebsiella pneumoniae in an emerging sequence type 307 lineage in a traveler returning from Puerto Rico to the Dominican Republic. Phylogenetic analyses indicate regional dissemination of this highly drug-resistant clone across the Americas, underscoring the need for adequate surveillance and infection control efforts to prevent further spread.

Intact Mycobacterium leprae Isolated from Placenta of a Pregnant Woman, China.

Whether Mycobacterium leprae transmits from placenta to fetus remains unknown. We describe the case of a pregnant woman with untreated histoid leproma. Although her newborn was healthy, laboratory examination revealed intact M. leprae present in the placenta, suggesting that the placental barrier might prevent vertical dissemination of M. leprae.

Chikungunya Fever Outbreak, Zhejiang Province, China, 2017.

We report a disease outbreak caused by chikungunya virus in Zhejiang Province, China, in August 2017. Phylogenic analysis indicated that this virus belonged to the Indian Ocean clade of the East/Central/South African genotype and was imported by a traveler returning from Bangladesh.

Feast of Sacrifice and Orf, Milan, Italy, 2015-2018.

Orf (ecthyma contagiosum) is an infection of the skin caused by a DNA virus belonging to the genus Parapoxvirus. We recently observed 7 cases of orf in Muslim men living in the metropolitan area of Milan, Italy, who acquired the infection after the Feast of Sacrifice.

Erwinia billingiae as Unusual Cause of Septic Arthritis, France, 2017.

In 2017 in France, we treated a patient with knee septic arthritis caused by Erwinia billingiae after trauma involving a palm tree. This rare pathogen could only be identified through 16S rRNA gene sequencing. For bacterial infections after injuries with plants, 16S rRNA gene sequencing might be required for species identification.

No Evidence for Role of Cutavirus in Malignant Melanoma.

Cutavirus was previously found in cutaneous melanoma. We detected cutavirus DNA in only 2/185 melanoma biopsies and in 0/52 melanoma metastases from patients in Germany. Viral DNA was localized in the upper epidermal layers. Swab specimens from healthy skin were cutavirus positive for 3.8% (9/237) of immunocompetent and 17.1% (35/205) of HIV-positive men.

Zoonotic Virus Seroprevalence among Bank Voles, Poland, 2002-2010.

Bank voles in Poland are reservoirs of zoonotic viruses. To determine seroprevalence of hantavirus, arenavirus, and cowpox virus and factors affecting seroprevalence, we screened for antibodies against these viruses over 9 years. Cowpox virus was most prevalent and affected by extrinsic and intrinsic factors. Long-term and multisite surveillance is crucial.


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