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13:35 EST 13th November 2018 | BioPortfolio

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Showing "Gilchrist Institute Achievement Sciences" PubMed Articles 76–100 of 4,500+

Research on the Scientific Evolution of the Flavonoid Agathisflavone.

Flavonoids are a group of secondary metabolites of the polyphenols class present in several plant species. Among them, the biflavonoid agathisflavone is of interest since it bears several biological effects that include: antiviral, antitumoral, antiprotozoal and neurogenic actions. In this sense, this study aims to use the important tool of scientific prospecting to assess the level of research development concerning the flavonoid agathisflavone.

Nano-sized Droplets of Self-Emulsifying System for Enhancing Oral Bioavailability of Chemotherapeutic Agent VP-16 in Rats: A Nano Lipid Carrier for BCS Class IV Drugs.

The purpose of this study was to investigate the ability of a self-nano-emulsifying drug delivery system (SNEDDS) to enhance the oral bioavailability of a BCS class IV drug, etoposide (VP-16).

An Alternative Cure: The Adoption and Survival of Bacteriophage Therapy in the USSR, 1922-1955.

Felix D'Herelle coined the term bacteriophage in 1917 to characterize a hypothetical viral agent responsible for the mysterious phenomenon of rapid bacterial death. While the viral nature of the "phage" was only widely accepted in the 1940s, attempts to use the phenomenon in treating infections started early. After raising hopes in the interwar years, by 1945 phage therapy had been abandoned almost entirely in the West, until the recent revival of interest in response to the crisis of antibiotic resistance....

Waking Up on the Wrong Side of the Bed: The Effects of Stress Anticipation on Working Memory in Daily Life.

The aim of this study was to examine the association between stress anticipated for the upcoming day and cognitive function later on that day, and how this relationship differed across age.

RNA biologist Joan Steitz awarded the 2018 Lasker~Koshland Special Achievement prize.

Vision-Related Quality of Life in Iranian Patients With Keratoconus: National Eye Institute Vision Function Questionnaire-25.

Use of patient-reported outcomes to evaluate the impact of ocular conditions on quality of life (QoL) is rising. Hence, the aims of this study were to determine the impact of keratoconus on QoL, and assess the National Eye Institute of the United States Vision Function Questionnaire (NEI-VFQ) performance in an Iranian population.

Colloidal transport through trap arrays controlled by active microswimmers.

We investigate the dynamics of a binary mixture consisting of active and passive colloidal particles diffusing in a two-dimensional array of truncated harmonic wells, or traps. We explore the possibility of using a small fraction of active particles to manipulate a much larger fraction of passive particles, for instance, to confine them in or extract them from the traps. The results of our study have potential application in biology and medical sciences, for example, to remove dead cells or undesired c...

Assessing the Physicochemical Stability of a Compounded Neonatal Trace Element Solution.

Alberta Health Services (AHS) recommends the adoption of a new neonatal multi-trace element formulation containing zinc sulfate, copper sulfate, selenious acid and sodium iodide to be compounded internally in appropriate AHS pharmacies. The objective of this study was to assess the physicochemical stability of this formulation under commonly used storage conditions.

Collective Memory from a Psychological Perspective: (Trends in Cognitive Sciences 22, 438-451, 2018).

The role of parental affection and psychological control in adolescent athletes' symptoms of school and sport burnout during the transition to upper secondary school.

The transition from compulsory school to upper secondary school is a challenging period for adolescents. Especially challenging it can be for adolescents who aim to integrate two domains of achievement, such as an athletic career and academic education. The pressure from two intertwined achievement domains may make student-athletes vulnerable to symptoms of burnout. The study examined the role of mothers' and fathers' affection and psychological control as possible risk or protective factors in the symptoms...

A novel insight into fluid bed melt granulation: Temperature mapping for the determination of granule formation with the in-situ and spray-on techniques.

Right filter-selection for phase separation in equilibrium solubility measurement.

Development of injectable liposomes and drug-in-cyclodextrin-in-liposome formulations encapsulating estetrol to prevent cerebral ischemia of premature babies.

Spousal loss and change in cognitive functioning: An examination of temporal patterns and gender differences.

The study investigates whether the disadvantaged position of men in the adverse consequences of widowhood for health and mortality also exists for changes in cognitive health.

Pearce Bailey: The "Fifth Horseman" and the National Institute for Neurological Diseases and Blindness.

Pearce Bailey (1902-1976) had an active career focused on the growth and development of neurology as a specialty in the post-World War II era. He was a founding member of the American Academy of Neurology (AAN) and its second president from 1951 to 1953. In 1951, he was also appointed as the first director of the National Institute for Neurological Diseases and Blindness (NINDB), which is now the National Institute of Neurological Disorders and Stroke. Known as an excellent politician, Bailey's role at the ...

A Combined Computer-Aided Approach to Drive the Identification of Potential Epitopes in Protein Therapeutics.

The identification of fragment sequences, or motifs, within a therapeutic protein that may elicit an immune response when processed by T-cells can be provided by computer-aided approaches. Immunogenicity is a significant problem associated with protein therapeutics and should be investigated in the early stage of protein-based drug development to avoid treatment resistance and potentially life-threatening immune responses.

A Comparison of Single and Multi-Test Working Memory Assessments in Predicting Academic Achievement in Children.

Children assessed as having low working memory capacity have also been shown to perform more poorly than their same-aged peers in measures of academic achievement. Early detection of working memory problems is, therefore, an important first step in reducing the impact of a working memory deficit on the development of academic skills. In this study, we compared a single-test assessment, the Working Memory Power Test for Children (WMPT) and a multi-test assessment, the Automated Working Memory Assessment (AWM...

Osteoporotic vertebral fracture prevalence varies widely - answer.

I read the letter by Gilchrist & al. with a great interest (1). The Authors address two major problems of vertebral fracture (diagnosis, reporting) and their consequences in the clinical practice. In a large database, the Authors found all patients who had medical and radiological reports suggestive of vertebral fracture. One third of them did not have vertebral fracture. This high percentage of false positives may be related to the lack of clear diagnostic criteria and probably to suboptimal training. This...

Preparation for Old Age - The Role of Cultural Context and Future Perceptions.

Preparation for age-related changes is a central task in midlife and older age and a determinant of functioning and well-being in later life. If and how people prepare is influenced by societal and institutional circumstances and also by beliefs about aging and the future.

Co-existing colloidal phases in artificial intestinal fluids assessed by AF4/MALLS and DLS: A systematic study into cholate & (lyso-) phospholipid blends, incorporating celecoxib as a model drug.

Purchasing Over The Counter (OTC) Medicinal Products Containing Codeine - Easy Access, Advertising, Misuse and Perceptions of Medicinal Risk.

Codeine containing medicines can carry a number of health risks associated with the increase in reported misuse and dependence, however they are still readily available over the counter (OTC) in many countries. The aim of this novel study was to report on the results of a survey of customers purchasing OTC codeine containing medicinal products at pharmacies in Ireland, South Africa and England; exploring use, sources of knowledge and perception of risks.

Pharmaceutical Characterization of MyoNovin, a Novel Skeletal Muscle Regenerator: in silico, in vitro and in vivo Studies.

MyoNovin is a novel skeletal muscle-regenerating compound developed through synthesis of two nitro groups onto a guaifenesin backbone to deliver nitric oxide to skeletal muscle with a potential to treat muscle atrophy. The purpose of this study was to utilize in silico, in vitro, and in vivo approaches to characterize MyoNovin and examine its safety, biodistribution, and feasibility for drug delivery.

Early rehabilitation after stroke: strong recommendations but no achievement in the French Acute Healthcare Facilities.

The Effects of Weak Static Magnetic Field on the Development of Organotypic Tissue Culture in Rats.

The effects of weak static magnetic field on the organotypic tissue culture of the rat cerebral cortex, liver, and spleen have been investigated. Exposure to a 200 μT static magnetic field induces tissue development, leading to the intensification of regeneration processes compared to the control explants.

Wilhelm Schulthess, Pioneer in the Treatment of Spinal Deformities: The Testimony of the Rizzoli Orthopedic Institute.

The manuscript describes the testimony of the Rizzoli Orthopedic Institute about Wilhelm Schulthess, a pioneer in the treatment of spinal deformities.

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