PubMed Journals Articles About "Arms Race Between Bacteria Their Phage Foes" - Page: 4 RSS

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Showing "arms race between bacteria their phage foes" PubMed Articles 76–100 of 4,400+

Affective Feelings and Perceived Exertion During a 10-km Time Trial and Head-to-Head Running Race.

To verify the affective feelings (AFs) and rating of perceived exertion (RPE) responses during a 10-km competitive head-to-head (HTH) running race and compare them with a time-trial (TT) running race.

An experimental mouse model for phage therapy of bacteremia by monovalent and polyvalent phage preparations.

A minimum lethal dose on mice for five bacterial pathogens were identified with PCR of neonatal septicemia of Escherichia coli, Klebsiella pneumoniae, Haemophilus influenzae, Pseudomonas aeruginosa, Citrobacter freundii and Moraxella catarrhalis were studied. Bacteriophage preparations active against 10 isolates of E. coli, 10 isolates of K. pneumoniae, 4 isolates of H. influenzae, 3 isolates of P. aeruginosa, 1 isolate of C. freundii and 1 isolate of M. catarrhalis were tested for their efficacy in treatme...

Planctopirus ephydatiae, a novel Planctomycete isolated from a freshwater sponge.

The microbiome of freshwater sponges is rarely studied, and not a single novel bacterial species has been isolated and subsequently characterized from a freshwater sponge to date. A previous study showed that 14.4% of the microbiome from Ephydatia fluviatilis belong to the phylum Planctomycetes. Therefore, we sampled an Ephydatia sponge from a freshwater lake and employed enrichment techniques targeting bacteria from the phylum Planctomycetes. The obtained strain spb1 was subject to genomic and phenomic cha...

Pre-planned Vs. Executed Real-Time Pacing Strategies during 3-km Race: Role of Rating Perceived Exertion.

: The aim of the study was to verify the agreement between preplanned and executed pacing during a 3-km race and determine whether adjustments are mediated by the rating of perceived exertion (RPE). : Thirteen young runners (eight males and five females, 17.5 ± 2.1 and 17.0 ± 1.6 years old, respectively) with national and international experience participated in the study. Before the simulated competition, the athletes informed of their preplanned pacing for the distance through a dashboard with the ...

Cadmium-Bacteria Complexation and Subsequent Bacteria-Facilitated Cadmium Transport in Saturated Porous Media.

Cadmium (Cd) contamination is becoming a significant environmental concern due to its persistency in soil. In the subsurface, the fate and transport of Cd are significantly affected by the presence of organic carriers, including bacteria, which are ubiquitous. In this research, facilitated Cd transport by four different bacterial strains in zeolite was investigated by column experiments under three different Cd introduction scenarios (i.e., a Cd and bacteria mixture, Cd and bacteria introduced separately bu...

Molecular Anatomy of the Receptor Binding Module of a Bacteriophage Long Tail Fiber.

Tailed bacteriophages (phages) are one of the most abundant life forms on Earth. They encode highly efficient molecular machines to infect bacteria, but the initial interactions between a phage and a bacterium that then lead to irreversible virus attachment and infection are poorly understood. This information is critically needed to engineer machines with novel host specificities in order to combat antibiotic resistance, a major threat to global health today. The tailed phage T4 encodes a specialized devic...

Characterization and genome analysis of B1 sub-cluster mycobacteriophage PDRPxv.

Mycobacteriophages are viruses specific to mycobacteria that have gained attention as alternative therapeutic strategies for treating antibiotic-resistant infections. Mycobacteriophages are highly diverse and have been grouped into 29 clusters, 63 sub-clusters and 10 singletons based on the genome sequence. Here, we annotate the genome of PDRPxv, a lytic mycobacteriophage isolated from New Delhi; it belongs to the Siphoviridae family as determined by transmission electron microscopy. This phage survives at ...

Comparative United States autoimmune disease rates for 2010-2016 by sex, geographic region, and race.

AIDs may disproportionately impact specific racial groups, but autoimmune (AID) prevalence information by minority racial group is sparse for many AIDs. The objective of this analysis was to supplement previously published AID prevalence rates by providing information on race rate ratios (minority race populations compared to Caucasian populations) in the United States. Preliminary to estimating race rate ratios, contemporary US-specific, health care utilization-based AID prevalence rates and female-to-male...

Impact of race on the association of mineral metabolism with heart failure: the Multi-Ethnic Study of Atherosclerosis.

Alterations in mineral metabolism, such as high phosphorus, high parathyroid hormone (PTH) and high fibroblast growth factor-23 (FGF-23) have been identified as potential risk factors for heart failure (HF). Important differences in the prevalence of mineral metabolism abnormalities and in the risk of HF have been reported across race/ethnic groups. In this study, we evaluated whether the associations of mineral metabolism markers with HF differed by race/ethnicity.

A bacteriophage mimic of the bacterial nucleoid-associated protein Fis.

We report the identification and characterization of a bacteriophage λ-encoded protein, NinH. Sequence homology suggests similarity between NinH and Fis, a bacterial nucleoid-associated protein involved in numerous DNA topology manipulations, including chromosome condensation, transcriptional regulation and phage site-specific recombination. We find that NinH functions as a homodimer and is able to bind and bend double-stranded DNA in vitro. Furthermore, NinH shows a preference for a 15 bp signature sequen...

The geographic mosaic in parallel: matching patterns of newt tetrodotoxin levels and snake resistance in multiple predator-prey pairs.

The Geographic Mosaic Theory of Coevolution (GMTC) predicts that coevolutionary arms races will vary over time and space because of the diverse ecological settings and population histories of interacting species across the landscape. Thus, understanding coevolution may require investigating broad sets of populations sampled across the range of the interaction. In addition, comparing coevolutionary dynamics between similar systems may reveal the importance of specific factors that structure coevolution. Here...

Phage Therapy for treatment of virulent Klebsiella pneumoniae infection in mouse model.

Klebsiella pneumoniae is an important emerging pathogen of humans and animals which may lead to major clinical implications including mortality. Moreover the increased use of antibiotics has promoted emergence of carbapenem resistant strains and extended spectrum β-lactamase producers (ESBLs) of K. pneumoniae. Recently, phage therapy has gained momentum as a conceivable alternative against emerging antibiotic resistance.

Regular compression therapy may not be necessary for lymphedema in arms without a subcutaneous echo-free space.

To study the effect of prolonged complex decongestive therapy (CDT) on lymphedema in arms without a subcutaneous echo-free space on subcutaneous tissue ultrasonography.

The neurosurgery applicant's "arms race": analysis of medical student publication in the Neurosurgery Residency Match.

Neurosurgery is consistently one of the most competitive specialties for resident applicants. The emphasis on research in neurosurgery has led to an increasing number of publications by applicants seeking a successful residency match. The authors sought to produce a comprehensive analysis of research produced by neurosurgical applicants and to establish baseline data of neurosurgery applicant research productivity given the increased emphasis on research output for successful residency match.

Identification of Plasmodium knowlesi Merozoite Surface Protein-1 (PkMSP-1 ) novel binding peptides from a phage display library.

Plasmodium knowlesi, the fifth human malaria parasite, has caused mortality in humans. We aimed to identify P. knowlesi novel binding peptides through a random linear dodecapeptide phage display targeting the 19-kDa fragment of Merozoite Surface Protein-1 protein.

Oral vinorelbine versus intravenous vinorelbine, in combination with epirubicin as first-line chemotherapy in Chinese patients with metastatic breast cancer.

Oral VRL offers easier administration, better quality of life, and cost saving. This study aimed to evaluate the treatment efficacy in terms of tumor response of the two formulations of vinorelbine (VRL, oral and IV) in combination with epirubicin (EPI); and the effect of EPI co-administration on VRL pharmacokinetics (PK) in Chinese patients with metastatic breast cancer (MBC) using a phase 2, open label, randomized trial. Patients were aged 18-70 years, had histologically confirmed MBC, Karnofsky Performa...

Modeling the effects of musculoskeletal geometry on scapulohumeral muscle moment arms and lines of action.

Biomechanical investigations examining shoulder function commonly observe a high degree of inter-individual variability in muscle activity and kinematic patterns during static and dynamic upper extremity exertions. Substantial differences in musculoskeletal geometry between individuals can alter muscle moment arms and lines of action that, theoretically, alter muscle activity and shoulder kinematics. The purposes of this research were to: (i) quantify model-predicted functional roles (moment arms, lines of ...

Association of Race with Survival in Intracranial WHO Grade II and III Meningioma in the United States: A Systematic Literature Review.

Recent literature has shown significant differences in meningioma incidence between different races, but minimal conclusive data exists on the role of race and ethnicity in overall survival for patients with high-grade intracranial meningioma. We conducted a systematic review to investigate the impact of race and ethnicity on survival in patients with high-grade intracranial meningioma.


The discovery of Sodium-Glucose co-transporter-2 (SGLT2) inhibitors had rewritten the treatment of diabetes mellitus with an impressive fall in incidence of death and associated complications.

In vitro evaluation of the effects of Ultrasound Tongue Scraper on bacteria and biofilm formation.

Oral malodor is a common condition caused by some Gram-negative oral bacteria, among which are the 3 red complex bacteria (RCB). The present study investigated the effectiveness of the Ultrasound Tongue Scraper (UTS) to disrupt the structural morphology of the bacteria and their biofilm.

Cardiac structure and function in response to a multi-stage marathon over 4486 km.

To investigate whether participation in the Trans Europe Foot Race 2009 (TEFR), an ultramarathon race held over 64 consecutive days and 4486 km, led to changes in cardiac structure and function.

Race and Ethnicity Gaps in Global Hidradenitis Suppurativa Clinical Trials.

Hidradenitis suppurativa (HS) is an often-debilitating disease characterized by chronic and recurrent painful nodules, abscesses, and sinus tracts affecting the intertriginous areas. Despite evidence in the literature of varying prevalence of HS among different racial and ethnic groups, no studies have evaluated the overall generalizability of clinical trial results considering the increased prevalence of HS among African American populations. Additionally, there is a paucity of data exploring the distribut...

Male-to-Female Ratios, Race/Ethnicity, and Spontaneous Preterm Birth among 11 Million California Infants.

 An observed disparity in population-scale data are a larger number of males among preterm births (PTBs). We investigated spontaneous PTB risk among women of various race/ethnic groups in combination with infants' sex.

The Association Between Race/Ethnicity and Revision Following ACL Reconstruction in a Universally Insured Cohort.

There have been few large studies involving multiethnic cohorts of patients treated with anterior cruciate ligament reconstruction (ACLR), and therefore, little is known about the role that race/ethnicity may play in the differential risk of undergoing revision surgery following primary ACLR. The purpose of this study was to evaluate whether differences exist by race/ethnicity in the risk of undergoing the elective procedure of aseptic revision in a universally insured cohort of patients who had undergone A...


Researchers typically identify health disparities using self-reported race/ethnicity, a measure identifying individuals' social and cultural affiliations. In this study, we use data from Waves 1, 3, and 4 of Add Health to examine health disparities by interviewer-ascribed skin color, a measure capturing the perceptions of race/ethnicity ascribed to individuals by others. Individuals with darker skin tones may face greater exposure to serious stressors such as perceived discrimination, poverty, and economic ...

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