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Human cytomegalovirus (HCMV) infection is the most common congenital infection in developed countries. Recent studies highlighted similar percentages of symptoms in HCMV congenitally-infected infants following either primary or non-primary maternal infections.
The purpose of this analysis was to conduct summative usability evaluations, including behavioral and subjective evaluations, for the fentanyl iontophoretic transdermal system (ITS).
Management of the patient with moderate to severe brain injury in any environment can be time consuming and resource intensive. In the austere or hostile environment, the challenges to deliver care to this patient population are magnified. These guidelines have been developed by acknowledging commonly recognized recommendations for neurosurgical and neuro-critical care patients and augmenting those evaluations and interventions based on the experience of neurosurgeons, trauma surgeons, and intensivists who ...
Depression and acute coronary syndromes (ACS) are both common public health challenges. Patients with ACS often develop depression, which in turn adversely affects prognosis. Low-cost, sustainable, and effective service models that integrate depression care into the management of ACS patients to reduce depression and improve ACS outcomes are critically needed. Integrating Depression Care in ACS patients in Low Resource Hospitals in China (I-CARE) is a multicenter, randomized controlled trial to evaluate the...
A 2-month-old girl with abnormal facial features and malnutrition presented for placement of a gastrostomy tube. The surgery was performed under general anesthesia using a laryngeal mask airway (LMA); however, after removal of the LMA, the patient had recurrent airway collapse, requiring repeated insertion of the LMA. The authors describe the management of this problem with the use of a tongue suture and anterior traction in the postoperative period in a resource-limited setting.This is an open-access artic...
Bee population declines are often linked to human impacts, especially habitat and biodiversity loss, but empirical evidence is lacking. To clarify the link between biodiversity loss and bee decline, we examined how floral diversity affects (reproductive) fitness and population growth of a social stingless bee. For the first time, we related available resource diversity and abundance to resource (quality and quantity) intake and colony reproduction, over more than two years. Our results reveal plant diversit...
This is an update to the previously published Saudi guidelines for the evaluation and medical and surgical management of patients diagnosed with prostate cancer. Prostate cancer is categorized according to the stage of the disease using the tumor node metastasis staging system 7 edition. The guidelines are presented with supporting evidence levels based on a comprehensive literature review, several internationally recognized guidelines, and the collective expertise of the guidelines committee members (autho...
Ecologically dominant species often define ecosystem states, but as human disturbances intensify, their subordinate counterparts increasingly displace them. We consider the duality of disturbance by examining how environmental drivers can simultaneously act as a stressor to dominant species and as a resource to subordinates. Using a model ecosystem, we demonstrate that CO -driven interactions between species can account for such reversals in dominance; i.e., the displacement of dominants (kelp forests) by s...
To compare the performance of self-collected vaginal (V) specimens with clinician-collected cervical (C) specimens for detection of high-risk human papillomavirus (hrHPV) and cervical disease using the Cepheid Xpert HPV, Roche Cobas 4800 HPV, and Hologic Aptima HPV assays.
To provide the reader with a comprehensive but concise understanding of congenital scoliosis METHODS: We have undertaken to summarize available literature on the pathophysiology, epidemiology, and management of congenital scoliosis.
Wildlife living around urbanized areas is often a cause of crucial issues such as zoonosis and wildlife-vehicle collisions. Despite this, residents hold positive views on the presence of urban wildlife primarily due to aesthetic reasons. This accepting attitude towards our coexistence with urban wildlife has made it difficult for wildlife managers to come to a consensus concerning the importance of human-urban wildlife conflicts. Although countermeasures such as lethal force and/or fencing are commonly used...
Neurologic disorders contribute significantly to both morbidity and mortality among children in resource-limited settings, but there are a few succinct studies summarizing the epidemiology of neurologic disorders in these settings. A review of available literature was performed to identify data on the prevalence, etiology, outcomes, and treatment of neurologic disorders in children in resource-limited settings. The burden of neurologic disorders in children is high in resource-limited settings. Barriers to ...
Adolescence is a critical time when the majority of tobacco users initiate smoking. Contingency management for adolescent smoking cessation has shown promise in previous studies, but efficacy following removal of contingencies is not well understood. The current study examined a remote form of contingency management among non-treatment seeking adolescent smokers.
As the global population of free-ranging domestic dogs grows, there is increasing concern about impacts on human health and wildlife conservation. Effective management of dog populations requires reliable information on their diet, feeding behavior, and social ecology. Free-ranging dogs are reliant on humans, but anthropogenic food subsidies, particularly human faeces (i.e., coprophagy) have not previously been fully quantified. In this study we assess the contributions of different food types to the diet, ...
Thirst is one of the most common and yet undertreated symptoms in the postoperative period, mainly because of the lack of safety criteria to support indication for thirst management strategies. A Safety Protocol for Thirst Management was developed and validated, and the objective of this article was to evaluate the inter-rater reliability of the protocol.
Management of traumatic splenic injury may be operative or non-operative (including embolization and conservative management). Traditionally, haemodynamic instability has been an indication for operative intervention. We aimed to report our experience of managing traumatic splenic injury at a regional major trauma centre in the UK over a 4-year period, with a particular focus on the non-operative management (NOM) of haemodynamically unstable patients.
We examined the contemporary incidence, types, predictors, angiographic characteristics, management and outcomes of coronary perforation.
To evaluate the insertion results of a novel straight array (EVO) by detailed imaging and subsequent histology in human temporal bones (TB).
Currently, there is limited knowledge about the experiences and challenges type 2 diabetes (T2D) patients face when intensifying from basal insulin to more complex regimens. The purpose of this study was to examine the experiences of adults with T2D who have been intensified to a basal-bolus insulin regimen, including challenges related to intensification, medication adherence issues, non-persistence, and healthcare resource use related to intensification.
Invasive aquatic weed management is one of the biggest challenges in the field of solid waste management. Eichhornia crassipes, Pistia stratiotes and Hydrilla verticillata (L.f.) Royle pose some of the world's most noted aquatic weed problems. Previously reported studies on management of H. verticillata, a submersed aquatic plant, have shown that temporary removal, chemical treatment or biological control methods each have advantages and disadvantages. Removal programs that propose to compost harvested H. v...