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2019 Sickle Cell Disease Guidelines American Society Hematology PubMed articles on BioPortfolio. Our PubMed references draw on over 21 million records from the medical literature. Here you can see the latest 2019 Sickle Cell Disease Guidelines American Society Hematology articles that have been published worldwide.
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Pneumococcal vaccination has decreased the bacteremia rate in both the general pediatric and sickle cell disease (SCD) populations. Despite this decrease, and an increasing concern for antibiotic resistance, it remains standard practice to obtain blood cultures and administer antibiotics in all febrile (>38.5°C) patients with SCD. We conducted a systematic review and meta-analysis of the available studies of the prevalence of bacteremia in febrile patients with SCD.
The objective of this study is to examine risk factors for neonatal abstinence syndrome (NAS) among infants born to mothers with sickle cell hemoglobinopathies (SCH).
The Italian Association of Medical Oncology (AIOM) has developed clinical practice guidelines for the treatment of patients with advanced non-small cell lung cancer (NSCLC). In the current paper a panel of AIOM experts in the field of thoracic malignancies discussed the available scientific evidences, with the final aim of providing a summary of clinical recommendations, which may guide physicians in their current practice.
The classical diagnosis of preeclampsia is usually based on the fulfillment of 3 criteria: pregnancy > 20 weeks of gestation, proteinuria (2+ on dipstick or > 300 mg/24 h) and arterial hypertension ≥ 140/90 mm Hg. The current blood pressure cut off of 140/90 mm Hg was set by the American College of Obstetrics and Gynecology (ACOG)-issued practice bulletin of 2019, the 2013 Task Force and the guidelines prompted by the International Society for the Study of Hypertension in Pregnancy (ISSHP)...
In the following, novel developments in biomedical publishing important to all of our authors, reviewers and editors involved in the publication process at Acta Physiologica will be highlighted. Acta Physiologica's recommendations for authors focus on (a) the current implications of the revised ICMJE Guidelines, (b) the still recent European General Data Protection Regulation (GDPR) and (c) guidelines for experimental biomedical research involving animals. In addition, (d) Acta Physiologica follows the COPE...
The American Cancer Society's Great American Smokeout is an annual event that encourages smokers to make a plan to quit smoking (https://www.cancer.org/healthy/stay-away-from-tobacco/great-american-smokeout.html). The 44th annual Great American Smokeout will occur on November 21, 2019.
CLINICAL PRACTICE GUIDELINES FOR THE PERIOPERATIVE NUTRITION, METABOLIC, AND NONSURGICAL SUPPORT OF PATIENTS UNDERGOING BARIATRIC PROCEDURES - 2019 UPDATE: COSPONSORED BY AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS/AMERICAN COLLEGE OF ENDOCRINOLOGY, THE OBESITY SOCIETY, AMERICAN SOCIETY FOR METABOLIC & BARIATRIC SURGERY, OBESITY MEDICINE ASSOCIATION, AND AMERICAN SOCIETY OF ANESTHESIOLOGISTS
: The development of these updated clinical practice guidelines (CPG) was commissioned by the AACE, TOS, ASMBS, OMA, and ASA Boards of Directors in adherence with the AACE 2017 protocol for standardized production of CPG, algorithms, and checklists. : Each recommendation was evaluated and updated based on new evidence from 2013 to the present and subjective factors provided by experts. : New or updated topics in this CPG include: contextualization in an adiposity-based chronic disease complications-centric ...
The 4th version of Clinical Practice Guidelines for Hepatocellular Carcinoma was revised by the Japan Society of Hepatology, according to the methodology of evidence-based medicine and partly to the Grading of Recommendations Assessment, Development and Evaluation system, which was published in October 2017 in Japanese. New or revised recommendations were described, herein, with a special reference to the surveillance, diagnostic and treatment algorithms.
This report presents up-to-date evidence and expert consensus-based revisions to the ASPMN 2011 guidelines that inform interprofessional clinical decision-making for hospitalized adults receiving opioid analgesics.
Genetic diversity in the RH genes among sickle cell disease (SCD) patients is well described but not yet extensively explored in populations of racially diverse origin. Transfusion support is complicated in patients who develop unexpected Rh antibodies. Our goal was to describe RH variation in a large cohort of Brazilian SCD patients exhibiting unexpected Rh antibodies (antibodies against RH antigens to which the patient is phenotypically positive) and to evaluate the impact of using the patient's RH genoty...
Sickle cell disease (SCD) leads to significant morbidity and early mortality, and hematopoietic cell transplantation (HCT) is the only widely available cure, with impacts seen on SCD-related organ dysfunction. Outcomes are excellent following matched related donor (MRD) HCT, leading to significantly expanded application of this treatment over the past decade. The majority of SCD patients lack a MRD, but outcomes following alternative donor HCT continue to improve on clinical trials. Within this framework, w...
Morbid obesity is a barrier to kidney transplantation (KT) in patients with end-stage renal disease (ESRD). Laparoscopic sleeve gastrectomy (SG) is an increasingly considered intervention, but the safety and long-term outcomes are uncertain. We reviewed prospectively collected data on patients with ESRD and chronic kidney disease (CKD) undergoing SG from 2011 to 2018. 198 patients with ESRD and 45 patients with CKD (stages 1-4) met NIH guidelines for bariatric surgery and underwent SG. 72% and 48% achieved ...
Families coping with sickle cell disease (SCD) often face heightened psychosocial risk factors, and research in pediatric SCD has often focused more on this area than resiliency factors. The aim of this study was to gain a better understanding of family resiliency in SCD based on caregiver perspectives. A secondary qualitative analysis was conducted with data from a mixed-methods study of caregivers of youth with SCD (n=22). Qualitative analyses involved coding based on 2 resiliency frameworks, organizing c...
Graft-versus-host disease (GvHD) is an important challenge and one of the major causes of morbidity and mortality in children after hematopoietic stem cell transplantation (HSCT). Herein, we report our institution's experience of a goal-oriented Bayesian monitoring for cyclosporine (CsA) used alone as GvHD prophylaxis during the post-transplant period in pediatric patients with Thalassemia Major (TM) or Sickle Cell Anemia (SCA) undergoing HLA-matched HSCT. We also studied evolution of chimerism. Twenty-six ...
Microparticles are sub-micron vesicles possessing protein and other materials derived from the plasma membrane of their parent cells, and literature suggests that they may have a role in the pathophysiology and downstream manifestations of sickle cell disease (SCD). The contributions of red blood cells microparticles (RMP) to the pathogenic mechanisms and clinical phenotypes of SCD are largely unknown. There is a controversy as to whether the proportions of intravascular hemolysis (approximately ≤ 30% o...
Cell-based therapies, defined here as the delivery of cells in vivo to treat disease, have recently gained increasing public attention as a potentially promising approach to restore structure and function to musculoskeletal tissues. Although cell-based therapy has the potential to improve the treatment of disorders of the musculoskeletal system, there is also the possibility of misuse and misrepresentation of the efficacy of such treatments. The medical literature contains anecdotal reports and research stu...
Invariant natural killer T (iNKT) cells are being considered as potential targets for immunotherapeutic strategies in a variety of conditions including sickle cell disease (SCD). However, relatively little is known about the fate of iNKT cell subsets in children with SCD. Herein, quantitative and qualitative analyses of circulating iNKT cell subsets were carried out in 120 children in steady state and 30 healthy controls. Children with SCD displayed significantly elevated levels of circulating iNKT cell sub...