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PubMed Journals Articles About "Brown Shoe Company" - Page: 5 RSS

00:12 EDT 20th June 2018 | BioPortfolio

Brown Shoe Company PubMed articles on BioPortfolio. Our PubMed references draw on over 21 million records from the medical literature. Here you can see the latest Brown Shoe Company articles that have been published worldwide.

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Showing "Brown Shoe Company" PubMed Articles 101–125 of 544

Decarboxylation of Indomethacin Induced by Heat Treatment.

As crystalline indomethacin is heated and subsequently cooled, it transforms into glassy indomethacin. While the original crystals are off-white in color, the glass becomes blackish-brown via a yellow intermediate stage. TLC of the components of the glass revealed three bands. The yellow component, which is generated either under hypoxic conditions or in the dark, was elucidated by NMR spectroscopy to be a decarboxylated fragment produced by thermal degradation. The colorless component is proposed to be for...


The Apolipoprotein M/S1P Axis Controls Triglyceride Metabolism and Brown Fat Activity.

Apolipoprotein M (apoM) is the carrier of sphingosine-1-phosphate (S1P) in plasma high-density lipoproteins. S1P is a bioactive lipid interacting with five receptors (S1P1-5). We show that lack of apoM in mice increases the amount of brown adipose tissue (BAT), accelerates the clearance of postprandial triglycerides, and protects against diet-induced obesity (i.e., a phenotype similar to that induced by cold exposure or β3-adrenergic stimulation). Moreover, the data suggest that the phenotype of apoM-defic...

"Robust, replicable, and theoretically-grounded: A response to Brown and Coyne's (2017) commentary on the relationship between emodiversity and health": Correction to Quoidbach et al. (2018).

Reports an error in "Robust, replicable, and theoretically-grounded: A response to Brown and Coyne's (2017) commentary on the relationship between emodiversity and health" by Jordi Quoidbach, Moïra Mikolajczak, June Gruber, Ilios Kotsou, Aleksandr Kogan and Michael I. Norton (, 2018[Mar], Vol 147[3], 451-458). In the article, there is an error in the byline for the first author due to a printer error. The complete, correct institutional affiliation for Jordi Quoidbach is ESADE Business School, Ramon Llull ...


Brown adipose tissue derived ANGPTL4 controls glucose and lipid metabolism and regulates thermogenesis.

Brown adipose tissue (BAT) controls triglyceride-rich lipoprotein (TRL) catabolism. This process is mediated by the lipoprotein lipase (LPL), an enzyme that catalyzed the hydrolysis of triglyceride (TAG) in glycerol and fatty acids (FA), which are burned to generate heat. LPL activity is regulated by angiopoietin-like 4 (ANGPTL4), a secretory protein produced in adipose tissues (AT), liver, kidney, and muscle. While the role of ANGPTL4 in regulating lipoprotein metabolism is well established, the specific c...

Investigating the impact of age-depended hair colour darkening during childhood on DNA-based hair colour prediction with the HIrisPlex system.

Predictive DNA analysis of externally visible characteristics exerts an increasing influence on contemporary forensic and anthropological investigations, with pigmentation traits currently being the most advanced for predictive modelling. Since pigmentation prediction error in some cases may be due to the result of age-related hair colour darkening, and sex influence in eye colour, this study aims to investigate these less explored phenomena on a group of juvenile individuals. Pigmentation phenotypes of chi...

Surgical Management of Brown Syndrome.

Misdiagnosed as osteosarcoma: Brown tumour in a haemodialysis patient.

FGF21 mimetic antibody stimulates UCP1-independent brown fat thermogenesis via FGFR1/βKlotho complex in non-adipocytes.

Fibroblast Growth Factor 21 (FGF21) is a potent stimulator of brown fat thermogenesis that improves insulin sensitivity, ameliorates hepatosteatosis, and induces weight loss by engaging the receptor complex comprised of Fibroblast Growth Factor Receptor 1 (FGFR1) and the requisite coreceptor βKlotho. Previously, recombinant antibody proteins that activate the FGFR1/βKlotho complex were proposed to act as an FGF21-mimetic; however, in vivo action of these engineered proteins has not been well studied.

Residual level of dimethachlon in rice-paddy field system and cooked rice determined by gas chromatography with electron capture detector.

In this study, a modified quick, easy, cheap, effective, rugged and safe (QuEChERS) method coupled with gas chromatography (GC) with electron capture detection (ECD) was established to determine dimethachlon residues in paddy soil, rice husk, rice straw, brown rice and cooked rice. The limits of quantification of dimethachlon were 0.01 mg/kg for paddy soil, brown rice and cooked rice and 0.02 mg/kg for rice straw and rice husk. The mean recoveries were in the range 78.59%-104.7% with relative standard devia...

The Root of Atractylodes macrocephala Koidzumi Prevents Obesity and Glucose Intolerance and Increases Energy Metabolism in Mice.

Targeting energy expenditure offers a strategy for treating obesity more effectively and safely. In previous studies, we found that the root of Atractylodes macrocephala Koidzumi (Atractylodis Rhizoma Alba, ARA) increased energy metabolism in C2C12 cells. Here, we investigated the effects of ARA on obesity and glucose intolerance by examining energy metabolism in skeletal muscle and brown fat in high-fat diet (HFD) induced obese mice. ARA decreased body weight gain, hepatic lipid levels and serum total chol...

Ten Years HIV Free: An Interview with "The Berlin Patient," Timothy Ray Brown.

Methemoglobinemia: A Girl with 'Chocolate Brown' Colored Blood.

In vitro protective activity of South Australian marine sponge and macroalgae extracts against amyloid beta (Aβ) induced neurotoxicity in PC-12 cells.

South Australia is a biodiversity hotspot of marine sponges and macroalgae. This study aimed to evaluate the potential neuroprotective activity of extracts from these two marine sources by reducing the toxicity of human amyloid beta Aβ in a cell model assay using PC-12 cells. A total of 92 extracts (43, 13, 16, and 20 extracts from sponge of 8 orders and 17 families, green algae of 3 orders and 4 families, brown algae of 6 orders and 8 families, and red algae of 5 orders and 10 families, respectively) were...

Degradation and residues of indoxacarb enantiomers in rice plant, rice hull and brown rice using enriched S-indoxacarb formulation and enantiopure formulation.

A chiral liquid chromatography-tandem high resolution mass spectroscopic method was developed for the analysis of indoxacarb enantiomers in rice plant, rice hull and brown rice. Chiral separation of two enantiomers was carried out on a Superchiral S-OD column maintained at 20 °C and eluted with 0.3 mL/min methanol. Samples were extracted by acetonitrile solution with ultrasound and cleansed by dispersive solid-phase extraction of 50 mg of primary secondary amine and 50 mg of C18. This method was successful...

Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity.

Adipocytes possess remarkable adaptive capacity to respond to nutrient excess, fasting or cold exposure, and they are thus an important cell type for the maintenance of proper metabolic health. Although the endoplasmic reticulum (ER) is a critical organelle for cellular homeostasis, the mechanisms that mediate adaptation of the ER to metabolic challenges in adipocytes are unclear. Here we show that brown adipose tissue (BAT) thermogenic function requires an adaptive increase in proteasomal activity to secur...

Magnetic Resonance Findings at 3 Tesla in Brown Syndrome.

Red walnut: Characterization of the phenolic profiles, and activity and gene expression of selected enzymes related to the phenylpropanoid pathway in pellicle during walnut development.

A rare variant of walnut with a red seed coat (pellicle) was examined for alterations in the phenolic profiles during development. The red walnut (RW) pellicle was compared to two commonly-colored walnut varieties; 'Lara' (brown) and 'Fernor' (light brown). Furthermore, the activity of selected enzymes of the phenylpropanoid and flavonoid related pathways and the relative expression of phenylalanine ammonia lyase (PAL) and anthocyanidin synthase (ANS) structural genes were examined in the pellicles of the t...

GSK126 alleviates the obesity phenotype by promoting the differentiation of thermogenic beige adipocytes in diet-induced obese mice.

A close relationship between epigenetic regulation and obesity has been demonstrated in several recent studies. Histone methyltransferase enhancer of Zeste homolog 2 (Ezh2), which mainly catalyzes trimethylation of histone H3K27 to form H3K27me3 was found to be required for the differentiation of white and brown adipocytes in vitro. Here, we investigated the effects of the Ezh2-specific inhibitor GSK126 in a mouse model of obesity induced by a high-fat diet (HFD). We found that GSK126 treatment reduced body...

From the inside out: a new species of armoured catfish Corydoras with the description of poorly-explored character sources (Teleostei, Siluriformes, Callichthyidae).

A new species of the armoured catfish genus Corydoras is described from the Xingu-Tapajos ecoregion, Brazilian Amazon. The new species can be distinguished from its congeners by having the following combination of features: short mesethmoid, with anterior tip poorly developed, smaller than 50% of bone length; posterior margin of pectoral spine with serrations directed towards spine tip or perpendicularly oriented; infraorbital 2 only in contact with sphenotic; ventral laminar expansion of infraorbital 1 poo...

EFFECTS OF IN SITU SELENIUM EXPOSURE AND MATERNAL TRANSFER ON SURVIVAL AND DEFORMITIES OF BROWN TROUT (SALMO TRUTTA) FRY.

Offspring of wild adult brown trout exposed to a range of selenium (Se) concentrations were reared in a laboratory setting to primarily assess effects on survival and deformities. Maternal whole body Se concentrations ranged from 4.7 to 22.6 mg/kg dry weight (dw) for wild fish. Corresponding Se concentrations in embryos ranged from 6.2 to 40.3 mg/kg dw. Significant relationships were found between embryo and whole-body tissue concentrations. Increasing egg Se concentrations were correlated with decreasi...

Tandem mass spectrometry of fucoidan-derived fragments, labeled with heavy-oxygen.

A procedure for the partial depolymerization of sulfated fucans and selective labeling with (18)O was developed. A tandem electrospray ionization mass spectrometry (ESI MS/MS) was applied for the direct analysis of mixtures of structurally-different oligosaccharides, derived from the fucoidans of known structure. The presence of label allowed unambiguous distinguishing between the fragment ions of (0,2)X0-type at m/z 287 and (2,4)A-type at m/z 285, since (18)O at the reducing end gave +2 mass shifting. Thu...

The parenthood argument.

Don Marquis is well known for his future like ours theory (FLO), according to which the killing beings like us is seriously morally wrong because it deprives us of a future we can value. According to Marquis, human fetuses possess a future they can come to value, and thus according to FLO have a right to life. Recently Mark Brown has argued that even if FLO shows fetuses have a right to life, it fails to show that fetuses have a right to use their mother's body, evoking Judith Jarvis Thomson's famous violin...

Radiographic examination of keel bone damage in living laying hens of different strains kept in two housing systems.

A high prevalence of deviations and fractures of the keel bone is a widespread welfare problem in laying hens. The aim of this study was to experimentally investigate this multifactorial problem throughout the laying period and to compare the prevalence and severity in different layer lines and different housing systems. High performing white (WLA) and brown (BLA) pure bred layer lines and low performing white (R11, G11) and brown layer lines (L68) were kept in both single cages and a floor housing system. ...

Response of soil microbial communities to red mud-based stabilizer remediation of cadmium-contaminated farmland.

In this work, a field test was conducted to investigate the effects of heavy metal stabilizer addition on brown rice and microbial variables in a cadmium (Cd)-contaminated farmland from April to October in 2016. Compared with the control, red mud-based stabilizer (RMDL) effectively reduced the concentration of Cd in brown rice (with the removal rate of 48.14% in early rice, 20.24 and 47.62% in late rice). The results showed that adding 0.3 kg m-2 RDML in early rice soil or soil for both early and late ric...

Adaptive thermogenesis by dietary n-3 polyunsaturated fatty acids: Emerging evidence and mechanisms.

Brown/beige fat plays a crucial role in maintaining energy homeostasis through non-shivering thermogenesis in response to cold temperature and excess nutrition (adaptive thermogenesis). Although numerous molecular and genetic regulators have been identified, relatively little information is available regarding thermogenic dietary molecules. Recently, a growing body of evidence suggests that high consumption of n-3 polyunsaturated fatty acids (PUFA) or activation of GPR120, a membrane receptor of n-3 PUFA, s...


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