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The US National Library of Medicine and National Institutes of Health manage PubMed.gov which comprises of more than 29 million records, papers, reports for biomedical literature, including MEDLINE, life science and medical journals, articles, reviews, reports and books.
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Evidence from observational studies suggests that driving pressure is strongly associated with pulmonary injury and mortality, regardless of positive end-expiratory pressure (PEEP) levels, tidal volume or plateau pressure. Therefore, it is possible that targeting driving pressure may improve the safety of ventilation strategies for ARDS patients. However, the clinical effects of a driving pressure-limited strategy for ARDS has not been assessed randomized controlled trials.
Sleep Disordered Breathing (SDB) is associated with increased risk of adverse pregnancy outcomes, including gestational diabetes mellitus (GDM). GDM is a significant cause of maternal and infant morbidities. Assessing these risk factors concurrently may facilitate both the identification of women at GDM risk and the initiation of GDM prevention strategies.
Progression of idiopathic pulmonary fibrosis (IPF) is accompanied by worsening of symptoms, exercise capacity and health-related quality of life. However, the utility of patient-reported outcomes as predictors of mortality remains uncertain.
Hospitalized patients with acute-on-chronic hypercapnic respiratory failure due to obesity hypoventilation syndrome (OHS) have increased short-term mortality. It is unknown whether prescribing empiric positive airway pressure (PAP) at the time of hospital discharge reduces mortality compared to waiting for an outpatient evaluation (i.e. outpatient sleep study and outpatient PAP titration).
Lung cancer is the leading cause of cancer mortality in the United States. Certain groups are at increased risk of developing lung cancer and experience greater morbidity and mortality compared to the general population. Lung cancer screening provides an opportunity to detect lung cancer at an early stage when surgical intervention can be curative; however, current screening guidelines may overlook vulnerable populations with disproportionate lung cancer burden. This review aims to characterize disparities ...
Most studies determining the prevalence of airway obstruction are limited to short time periods.
The use of e-cigarettes has rapidly increased in the US and thousands of e-cigarette flavors are available. However, there remains a dearth of evidence on e-cigarette flavor use patterns among older e-cigarette users.
Obesity Hypoventilation Syndrome (OHS) is an undesirable consequence of obesity. Weight loss is an important component of management based upon clinical rationale, but the evidence supporting weight loss has not been summarized and the optimal approach has not been determined.
Poor lung function, a significant predictor of mortality, has been observed in post-menopausal women when compared to those still menstruating. Menopausal age is a risk factor for several adverse health outcomes, but little evidence exists on the impact of menopausal age on lung function impairments, especially on post-bronchodilator lung function measures.
Pulmonary Pathology Society Perspective on the 2018 American Thoracic Society, European Respiratory Society, Japanese Respiratory Society, and Latin American Thoracic Society (ATS/ERS/JRS/ALAT) Idiopathic Pulmonary Fibrosis Clinical Practice Guidelines.
Decreasing medication overuse represents an opportunity to avoid harm and costs in the era of value-based purchasing. Studies of inhaled corticosteroids (ICS) overuse in COPD has examined prevalent use. Understanding initiation of low-value ICS among complex patients with COPD may help shape de-adoption efforts.
Sleep constitutes a fundamental pillar of health in individuals and is an indicator of the health of a population.
Interpretation of spirometry is influenced by inherent limitations and by the normal or predicted reference values used. For example, traditional spirometric parameters such as "distal" airflows do not provide sufficient differentiating capacity, especially for mixed patterns or small airway disease.
The objective of this workshop was to determine current nursing research priorities in critical care, adult pulmonary, and sleep conditions through input from consumer (patient, family, and formal and informal caregivers) and nursing experts around the world. Working groups composed of nurses and patients selected potential research priorities based on patient insight and a literature review of patient-reported outcomes, patient-reported experiences, and processes and clinical outcomes in the focal areas. A...