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The US National Library of Medicine and National Institutes of Health manage PubMed.gov which comprises of more than 29 million records, papers, reports for biomedical literature, including MEDLINE, life science and medical journals, articles, reviews, reports and books.
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To investigate the risk factors and predictors of outcomes in a cohort of Chinese patients with cerebral venous sinus thrombosis (CVST), so as to provide a reference for customized clinical decision.
Diffusion tensor imaging (DTI) based on echo-planar imaging (EPI) can suffer from geometric image distortions in comparison to conventional anatomical magnetic resonance imaging (MRI). Therefore, DTI-derived information, such as fiber tractography (FT) used for treatment planning of brain tumors, might be associated with spatial inaccuracies when linearly projected on anatomical MRI. Hence, a non-linear, semi-elastic image fusion shall be evaluated in this study that aims at correcting for image distortions...
To evaluate the frequency of Medication Overuse Headache (MOH) in the patients with Chronic Daily Headache (CDH) using International Classification of Headache Disorder II Revision (ICHD II R) and International Classification of Headache Disorder 3 Beta (ICHD-3 beta) criteria. We also compare the CHD patients with and without MOH using both the criteria.
The factors influencing falls in idiopathic normal pressure hydrocephalus (iNPH) remain unclear, although iNPH-associated gait and balance disturbances can lead to an increased risk of falls. This study aimed to investigate the associations among fall status, gait variability, balance function in iNPH, and to identify fall-related factors in iNPH.
It is well known that social media influences politics and the economy. A new Web-based metric (Altmetrics) has recently been developed for use in scientific fields. The aim of this study was to determine which recent papers in the field of stroke have received the greatest amount of attention from the general public. The Altmetric Attention Score is an automatically calculated metric for monitoring social media.
We aimed to investigate the values of midbrain area in diagnosing Parkinson's Disease (PD) and progressive supranuclear palsy (PSP) by using transcranial sonography (TCS). Disease duration effect on brain sonographic findings could decrease the accuracy of TCS in PD and PSP patients. We reduced the disease duration effect on sonographic differences found between PD and PSP patients by using multivariate analysis.
Stereotactic radiosurgery (SRS) has been used as the primary treatment for vestibular schwannoma (VS) over the last two decades. While literature is available on tumor response following SRS, very long-term follow-ups are not yet available. Malignant transformation of benign VS is very rare. There are only a few cases described in the literature, most of which report malignant transformation occurring between 5-10 years after radiosurgery. Here we report a case of a 65-year-old female, with no family histor...
To find out the predictors of final visual outcome and recurrences in idiopathic intracranial hypertension (IIH).
A plate is commonly applied after anterior cervical discectomy and fusion (ACDF); particularly in cases of multilevel fusion. Recent comparative studies have focused on constrained versus semiconstrained plates, however little data is available to assess differences between semiconstrained plates.
Percutaneous treatments for trigeminal neuralgia (TN) include glycerol rhizotomy (GR), radiofrequency thermocoagulation (RF), and balloon compression (BC), which aim to provide pain relief by targeted injury to the trigeminal nerve pain fibers. All three techniques are well established and can provide immediate pain relief; however each of them can be associated with a range of complications. Our objective was to compare the safety and efficacy of GR, RF and BC in patients with TN. This study was performed ...
To assess the impact of tDCS on posture, gait and coordination of movements in subjects with cerebellar ataxia.
Intracranial hemorrhage (ICH) expansion is a predictor of poor clinical outcome. ICH expansion can be predicted with a swirl sign on noncontrast computed tomography (NCCT) and/or a spot sign on computed tomographic angiography (CTA). In this study, we aimed to evaluate the diagnostic value of a swirl sign and a spot sign in identifying hematoma expansion.
Blood-blister aneurysms (BBAs) of the internal carotid artery (ICA) are rare entities, but clinically important cause of subarachnoid hemorrhage (SAH). Several surgical and endovascular strategies have been attempted for these heterogeneous lesions. In this study, the authors analyzed the treatment strategy and outcomes in a series of cases of ICA blister aneurysms treated microsurgically.
Stereotactic registration for deep brain stimulation surgery is often performed after halo placement on an MRI or CT with fiducials. Cone-beam computed tomography scanners (CBCT) have been used for lead confirmation in DBS surgery. A new CBCT scanner has an enlarged field of view now allowing for visualization of fiducials, and the potential for intraoperative registration. The aim of this retrospective study was to evaluate the accuracy and precision of stereotactic registration using images obtained in in...
Gliosarcoma (GSM) is a variant of glioblastoma (GBM), the most common primary malignant brain tumor that occurs in adults. GSM is characterized by its biphasic components: the gliomatous and sarcomatous components and categorized into primary and secondary GSM. Intrinsic to the brain parenchyma, GSM is usually managed by gross total resection, and radiotherapy with/without chemotherapy. While the benefits of treatment remain unclear, cases have always been managed similar to GBM cases yielding different tre...
Delayed symptomatic hyponatremia is a known phenomenon occurring > 3 days after transsphenoidal surgery. This is a significant cause of post-operative emergency room visits and re-admissions. We describe and characterize post-operative hyponatremia in patients undergoing endoscopic transsphenoidal surgery, identify predictive factors, and create a clinical tool for predicting high risk patients.
Prognostic significance of O6-methylguanine-DNA-methyltransferase (MGMT) promoter methylation and isocitrate dehydrogenase-1 (IDH-1) mutation in glioblastoma multiforme patients: A single-center experience in the Middle East region.
To determine the prevalence and prognostic value of MGMT promoter methylation and IDH1 mutation in glioblastoma multiforme (GBM) patients from the Middle East.
The LACE + index (Length of stay, Acuity of admission, Charlson Comorbidity Index (CCI) score, and Emergency department visits in the past 6 months) is a tool utilized to predict 30-90 day readmission and other secondary outcomes. We sought to examine the effectiveness of this predictive tool in patients undergoing brain tumor surgery.
The patient was an 81-year-old woman. At age 73, she developed difficulties in climbing stairs and swallowing, and became unable to open bottles at age 74. She had been walking with a cane since age 76. Accidental chest X-ray findings showed bilateral hilar lymphadenopathy at age 78. Angiotensin converting enzyme (ACE) was elevated. Lymphocyte proliferation was prominent in bronchoalveolar lavage fluid. Sarcoidosis was suspected, but she was followed without treatment due to lack of respiratory symptoms. Sh...
In patients undergoing decompressive craniectomy for traumatic brain injury(TBI) there has been reported an incidence of hydrocephalus between 0-45%. There are several radiological and clinical features described in association with development of hydrocephalus. For study the influence of these factors we conducted a retrospective observational single-center cohort study in a tertiary care center with special attention to the transcalvarial herniation(TCH) volume after decompressive craniectomy.
Diagnosis of occult atrial fibrillation (AF) in stroke patients remains challenging. Several scores predictive of occult AF in stroke patients have been proposed, all based on the positive predictive value of clinical, biological, and radiological parameters, but they failed to modify the management of AF detection after stroke. The aim of this study was to identify a group of Stroke patients with Underlying Risk of Atrial Fibrillation (SURF) excluding stroke patients with low risk of AF.
The aim of this study was to identify perioperative risk factors of pulmonary complications (PC) after posterior instrumentation and fusion (PIF) for non-degenerative scoliosis and devise a predictive scoring system that could be used by spine surgeons to predict the level of risk requiring advanced measures.
Perivascular spaces (PVS) are involved in mechanisms of brain interstitial fluid and metabolic waste clearance. Since most of this clearance occurs during sleep, it is plausible that sleep-related disorders favor PVS dilatation. Knowledge on the association between enlarged basal ganglia (BG) PVS and sleep disorders is limited. Here, we aimed to assess the association between sleep parameters and enlarged BG-PVS in older adults.
Small vessel disease (SVD) has been associated with motor and cognitive impairments in neurodegenerative diseases. We investigated SVD markers using brain magnetic resonance imaging (MRI) and the global SVD score in Parkinson's disease (PD).