Track topics on Twitter Track topics that are important to you
The US National Library of Medicine and National Institutes of Health manage PubMed.gov which comprises of more than 29 million records, papers, reports for biomedical literature, including MEDLINE, life science and medical journals, articles, reviews, reports and books.
BioPortfolio aims to cross reference relevant information on published papers, clinical trials and news associated with selected topics - speciality.
For example view all recent relevant publications on Epigenetics and associated publications and clincial trials.
Information regarding patterns of smartphone usage, user preferences, and difficulties faced by patients is necessary to initiate any mHealth related programs.
To compare real-world characteristics and management of individuals aged 80 and older with heart failure (HF) and mid-range ejection fraction (HFmrEF) and heart failure with preserved ejection fraction (HFpEF) derived from a large cohort of survey and to compare them with those younger than 80 from the same survey.
This issue of the International Journal of Clinical Practice includes 4 articles regarding testing in medicine. Our Associate Editor for Cardiovascular Disease Prevention and Metabolic Diseases, Anthony Wierzbicki, together with Timothy Reynolds, start us off with a thoughtful extended editorial/perspective with the title (translated) "first, do no harm.". This article is protected by copyright. All rights reserved.
to examine the relationship between costs of hyperglycemia drug treatment and glycemic control among people with type 2 diabetes (T2D).
The past few decades have witnessed a surge in consumer, clinician and academic interest in the field of integrative health care (IHC). Yet, there is still uncertainty regarding the effectiveness of IHC for complex, long-term health conditions.
Up to half of all patients leave their outpatient clinic visit with an uncommunicated need. We designed the Clinic Satisfaction Tool (CST) as a low-cost, highly-utilized assessment of the spine clinic experience that improved communication in our multidisciplinary spine practice. The purpose of this study was to qualitatively analyze chief complaints and feedback from the CSTs to determine how spine clinic patients used the form, identify the most prevalent concerns, and mark areas for improvement.
There is currently no consensus on the effect of treatment with angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs), on the prognosis of patients with heart failure and preserved ejection fraction (HFpEF). Therefore, we have analyzed the relationship of commencing treatment with ACEIs or ARBs and the prognosis of patients with incident HFpEF.
This study assessed type 2 diabetes treatment outcomes and process indicators using a comprehensive type 2 diabetes patient cohort in North Karelia, Finland, from 2011 to 2016.
Few studies have evaluated the long-term impact of interventions on antibiotic prescription for lower respiratory tract infections (LRTI). This study was aimed at evaluating the use of antibiotics prescribed for LRTIs by general practitioners (GP) who underwent a multifaceted intervention carried out six years earlier.
To determine the relationship between trends in admission serum albumin and long term mortality in medical patients with hospital readmission.
Pathology is not usually a glamourous subject. However, this year things have been different. "Bad Blood" - a book - and not just a song by Taylor Swift, won the Financial Times/McKinsey Business book of the year award. A presentation by the author was a standing room only ticketed event at the American Association of Clinical Chemistry meeting this year. What was the story? It contained blondes, blood, bankers (ex-Goldman Sachs-appropriately), and Silicon Valley skullduggery - a film is being made. Yet, wh...
Progress marches on. The International Journal of Clinical Practice nows publishes on the web (https://onlinelibrary.wiley.com/journal/17421241) manuscripts as soon as they are accepted, even prior to formatting ("typesetting"). These can be found in the 'Accepted Articles' section and are fully citable and contain a Digital Object Identifier (DOI). This version of the published article does contain the caveat "This article has been accepted for publication and has undergone full peer review but has not bee...
Portal vein thrombosis (PVT) is a common complication amongst patients with liver cirrhosis. The PVT risk factors and its impact on post-liver transplant outcome has not been well defined, yet. This study aimed to investigate PVT prevalence, its risk factors and influence on early and long-term outcomes after liver transplantation.
Increasing demand for laboratory testing at weekends is common but little is known about its appropriateness.
Effect of prolonged treatment with phosphodiesterase-5-inhibitors on endothelial dysfunction in vascular diseases and vascular risk conditions: a systematic review analysis and meta-analysis of randomized double-blind placebo-controlled trials.
To challenge the argument that continuous use of phosphodiesterase-5 selective inhibitors may reduce endothelial cell dysfunction in patients with vascular diseases or vascular risk conditions.
To explore the practice and attitudes of uro-oncologists in the UK regarding monitoring testosterone levels and the use of testosterone replacement therapy (TRT) in their prostate cancer patients treated with androgen deprivation therapy (ADT).
The standard duration of administration of antimicrobial prophylaxis in surgery and non-surgical invasive therapy was shortened according to the promotion of appropriate use. Here, we conducted an intervention to optimize antimicrobial prophylaxis by revising all relevant clinical pathways based on the most recent guidelines.
Overdiagnosis appears to be an umbrella term, or an overarching category with various components, such as overdetection, overdefinition, or overselling. How these qualitative elements map on to the quantitative categories (true positives and negatives, false positives and negatives) as defined in screening test accuracy studies is not clear to me. Whilst on face value overdetection might seem to be equivalent to false positives, Brodersen and his colleagues are explicit that overdiagnosis is not a false pos...
Clinical practice guidelines (CPGs) have been published by the American College of Emergency Physicians (ACEP) since 1990 to advance evidence-based emergency care. ACEP clinical policies have drawn anecdotal criticism for bias, yet the overall quality of these guidelines has not previously been quantified. We sought to examine ACEP clinical policies using a recognized, validated appraisal instrument: Appraisal of Guideline for Research & Evaluation (AGREE II).
Diabetes is a chronic and complex disease that requires a multidisciplinary collaborative care approach.
Previous studies investigating the risk of suicide in patients with Parkinson's disease (PD) have reported conflicting results. This study evaluated suicide risk in PD and investigated the relationship between suicide risk and perceived disability, hopelessness and affective temperaments in PD.
Reducing unnecessary laboratory blood testing in the hospital setting represents a challenge to improve the adequacy of healthcare and a tricky task for teaching hospitals. Our hospital network, actively participates in the Choosing Wisely Campaign and is engaged in avoiding unnecessary low value interventions and investigations. We aimed to study whether a multi-level approach combining educational and web-system based interventions, could be effective in reducing laboratory testing and related costs.
Efficacy and safety of a triple active sore throat lozenge in the treatment of patients with acute pharyngitis: Results of a multi-centre, randomised, placebo-controlled, double-blind, parallel-group trial (DoriPha).
The aim of this multi-centre, randomised, double-blind, placebo-controlled trial was to compare the efficacy and safety of the fixed combination of 0.5 mg tyrothricin, 1.0 mg benzalkonium chloride, and 1.5 mg benzocaine (study drug marketed as Dorithricin ) in repeat dosing for 3 days to match placebo lozenges in the treatment of acute pharyngitis in adults.
Every month I am tasked with selecting articles to receive the label of "Editor's Choice" (EC), ensuring that the article is free to access forever. The goal is to highlight material that may not be easily available elsewhere or that provides an update to a hot topic. In some cases these EC choices are accompanied by an editorial. Does this mean greater attention will be paid to EC articles as measured in terms of downloads?. This article is protected by copyright. All rights reserved.
Evaluation of the impact of dutasteride/tamsulosin combination therapy on libido in sexually active men with lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH): a post hoc analysis of a prospective randomized placebo-controlled study.
Five-α reductase inhibitor (5ARI) therapy has been associated with sexual dysfunction in some patients. This study assessed the impact of a fixed-dose combination of the 5ARI dutasteride 0.5 mg and the α -adrenoceptor antagonist tamsulosin 0.4 mg (DUT-TAM FDC) on Men's Sexual Health Questionnaire (MSHQ) domain scores in patients with lower urinary tract symptoms secondary to benign prostatic hyperplasia (BPH).