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Sympathetic neural activation plays a key role in the incidence and maintenance of acute myocardial infarction (AMI) induced ventricular arrhythmia (VA). Furthermore, previous studies showed that AMI might induce microglia and sympathetic activation and that microglial activation might contribute to sympathetic activation. Recently, studies showed that light emitting diode (LED) therapy might attenuate microglial activation. Therefore, we hypothesized that LED therapy might reduce AMI-induced VA by attenuat...
We present a remarkable maximal capacity exercise test of a 52-year-old patient diagnosed with Brugada syndrome. As the patient reaches a supranormal sinus heart rate, the type 1 ECG pattern of Brugada syndrome appeared and then disappeared immediately after cessation of exercise. This article is protected by copyright. All rights reserved.
Ultra-high-density voltage mapping (uHD M) is a new tool that can add new insights in the pathophysiology of atrial fibrillation (AF). The aim of this study was to evaluate the performance of uHD M in predicting post-ablation AF recurrence (AFR).
Atrial fibrillation (AF) represents the most common cardiac arrhythmia worldwide; it poses a great burden in terms of quality of life reduction and yearly stroke risk. Left atrial appendage closure (LAAC) is a stroke prevention strategy that has been proven a viable alternative to anti-thrombotic regimens in non-valvular AF patients. LAAC can be performed as a stand-alone procedure or alongside a concomitant AF trans catheter ablation, in a procedure known as "Combined Procedure". Aim of this study is to su...
Advanced age is the foremost risk factor for atrial fibrillation (AF). Telomere length is a surrogate for biological aging, but the association between shortened leukocyte telomere length (LTL) and recurrence of AF after ablation remains inconclusive.
A 47 year old lady presented with recurrent episodes of palpitation. During one of the episodes a wide QRS tachycardia with left bundle branch block (LBBB) morphology was recorded that was reported to be reverted to sinus rhythm with amiodarone. Surface electrocardiogram did not show any pre-excitation. She did not have any structural heart disease by transthoracic echocardiogram. She has undergone an Electrophysiology study. Basal atrial-Hisian and His-ventricular intervals were within normal limits. There...
A 69-year-old woman underwent a second ablation procedure for recurrent atrial tachycardia (AT). She had undergone a mitral valvuloplasty, tricuspid valvuloplasty, excision of the left atrial (LA) appendage, Maze procedure, and pulmonary vein isolation for severe mitral regurgitation and persistent atrial fibrillation (AF) 2 months prior. This article is protected by copyright. All rights reserved.
An 82-year-old man underwent redo catheter ablation of ventricular tachycardia (VT) after anterior infarction. A ripple mapping conducting channel (RMCC) was identified within the anterior scar in the left ventricular epicardium during sinus rhythm. Along the RMCC, delayed potentials during sinus rhythm, a good pace map with a long stimulus to the QRS interval, and mid-diastolic potentials during VT were recorded, and epicardial ablation at this site eliminated the VT. These findings suggested that the RMCC...
A 50-year-old male underwent the catheter ablation procedure for persistent atrial tachycardia (AT). The patient had the past history of surgical mitral valvuloplasty and annuloplasty, tricuspid annuloplasty, and the biatrial Cox-Maze IV procedure for severe mitral regurgitation and recurrent paroxysmal atrial fibrillation. This article is protected by copyright. All rights reserved.
A 67-year-old lady underwent electrophysiologic testing because of recurrent palpitations. Atrio-His (AH) and His-ventricular intervals measure 98ms and 44ms, respectively. Retrograde conduction was midline and decremental. Dual atrio-ventricular (AV) nodal physiology was present and programmed atrial extra-stimulation induced a narrow complex tachycardia (NCT) after a critical AH delay. This article is protected by copyright. All rights reserved.
Impact of anti-coagulation therapy on outcomes in patients with cardiac implantable resynchronization devices undergoing transvenous lead extraction: a sub-study of the ESC-EHRA EORP ELECTRa (European Lead Extraction ConTRolled) Registry.
Little data are available on anticoagulation (AC) management in patients with cardiac resynchronization (CRT) devices who undergo lead extraction procedure (TLE). We investigated the impact of AC on peri-procedural complications in CRT patients undergoing TLE, enrolled in the ESC-EHRA European Lead Extraction ConTrolled (ELECTRa) registry.
Frequent premature ventricular complexes (PVCs) can lead to symptoms, cardiomyopathy and increased mortality. Beta-blockers are recommended as first-line therapy to reduce PVC burden; however, the response is unpredictable. The objective of this study is to determine whether PVC diurnal-variability patterns are associated with different clinical profiles and predict drug response.
Remote monitoring of implantable cardioverter-defibrillators has been associated with reduced rates of all-cause rehospitalizations and mortality among device recipients, but long-term economic benefits have not been studied.
The role of cryoballoon pulmonary vein isolation (PVI) for patients with persistent atrial fibrillation (AF) is controversial, since long-term success can be poor. We performed left atrial voltage mapping prior to cryoballoon PVI and determined AF-free survival depending on the extent of low-voltage areas.
Adenosine challenge (AC) can be used to evaluate possible Wolff-Parkinson-White (WPW) pattern on electrocardiogram (ECG). Despite the use of this technique, there is a paucity of studies in the pediatric population evaluating the efficacy, safety and outcomes of this testing modality. Methods and Results All ACs performed from January 2009 to June 2017 were retrospectively reviewed. Patient demographics, adenosine dosing, results, adverse effects, and outcomes including results of electrophysiology studies ...
Effect of cryoballoon and radiofrequency ablation for pulmonary vein isolation on left atrial function in patients with non-valvular paroxysmal atrial fibrillation: a prospective randomized study (Cryo-LAEF study).
Isolation of the pulmonary veins (PVI) has become mainstay in atrial fibrillation (AFib) therapy. Lesions in left atrial tissue lead to scar formation and this may affect left atrial function.
Second-generation cryoballoon ablation for recurrent atrial fibrillation after an index procedure with radiofrequency versus cryo: different pulmonary vein reconnection patterns but similar long-term outcome - results of a multicenter analysis.
Repeated procedures are often needed for long-term success of atrial fibrillation ablation. There are scarce data regarding cryoballoon use for such procedure.
The tricuspid valve is situated in close proximity to cardiac conduction tissue and damage to this tissue can affect postoperative rhythm. The aim of this study was to quantify the incidence of pacemaker requirement after tricuspid valve surgery and investigate predictors.
A 23-year-old gentleman presented with a history of palpitations. The 12-lead electrocardiogram (ECG) showed no manifest ventricular preexcitation. Echocardiogram was within normal limits. Retrograde study showed concentric activation of the atrium with decremental conduction. Atrial pacing from right atrial (RA) free wall showed progressive preexcitation. No anterograde nodal duality was documented. This article is protected by copyright. All rights reserved.
Recent studies suggest that implantable cardioverter defibrillators (ICDs) are associated with increased risk of cardiac implantable electronic device (CIED) infections when compared to permanent pacemakers (PPMs). However, there were controversies among studies. In this study we performed a systematic review and meta-analysis to explore the risk of device infection in ICD versus PPM.