PubMed Journal Database | Medical principles and practice : international journal of the Kuwait University, Health Science Centre RSS

13:59 EDT 17th October 2018 | BioPortfolio

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Showing PubMed Articles 1–25 of 216 from Medical principles and practice : international journal of the Kuwait University, Health Science Centre

Glutathione S-Transferases and Cytochrome P450 enzyme expression in patients with Intracranial Tumors: Preliminary Report of 55 Patients.

Intracranial tumors are one of the most frightening and difficult to treat tumor types. In addition to surgery, additional protocols such as chemotherapy and radiotherapy also take place in the treatment. Glutathione S-transferase (GST) and cytochrome P450 (CYP) enzymes are prominent drug metabolizing enzymes in human body. The aim of the present study is to show the expression of GSTP1, GSTM1, CYP1A1 and CYP1B1 in different types of brain tumors and to compare the results with current literature.

Proton Pump Inhibitors and the Risk of Dementia: is There a Link?

Dementia is one of the most common neurodegenerative disorder among older populations around the world, and the incidence is increasing. Many epidemiologic studies have considered the association between proton-pump inhibitors and dementia, yet the relationship is still controversial.The objective of this study was to validate whether or not proton-pump inhibitors is indeed associated with dementia.Materials (Subjects) and Methods: We searched for articles on clinical studies of dementia and proton pump inh...

Bladder Explosion During Transurethral Resection of the Prostate Repaired Laparoscopically: A Case Report and Review of Literature.

To report on a case of intravesical explosion during transurethral resection of prostate (TURP) which was managed laparoscopically and to review the relevant literature.

The Relationship between Maxillary Sinus Lateral Wall Thickness, Alveolar Bone Loss, and Demographic Variables: A Cross-sectional Cone Beam Computerized Tomography Study.

Sinus floor evelation and augmentation surgery is widely used as a reliable procedure to increase insufficient bone height in the posterior maxillary area. The purpose of the present clinical study was to determine the associations between periodontal bone loss (PBL), maxillary sinus lateral bone wall thickness, age, and gender using cone beam computerized tomography (CBCT).

Investigation of Therapeutic Effects of Erdosteine on Polycystic Ovary Syndrome in a Rat Model.

Polycystic ovary syndrome (PCOS) is a serious endocrine disorder. In the present study, we investigated the therapeutic effects of erdosteine in letrozole induced-PCOS in rats. Methods: Thirty two wistar albino female rats were grouped as control group (C), PCOS group (PCOS), PCOS-metformin group (PCOS+MET), PCOS-erdosteine group (PCOS+Erd). Polycystic ovary syndrome was induced by administering letrozole; such rats presented with sex hormone disorder, abnormal estrous cycles determined by daily vaginal sme...

Diet and Lifestyle Role in Homocysteine Metabolism in Turner's Syndrome.

Patients with Turner syndrome (TS) have an unfavorable cardiometabolic profile. Hyperhomocysteinemia is a potential cardiovascular risk factor influenced by genetic and environmental factors, therapies, unbalanced diets and other lifestyle factors. We retrospectively studied the relationship between total plasma homocysteine (Hcy), serum vitamin B12 (B12) and folate concentration (s-F) in TS patients, taking into account the genetic profile, diet, smoking habits, hormonal therapies and dietary supplements o...

Does Adding Various Accelerators to Mineral Trioxide Aggregate Negatively Effect Push-Out Bond Strength?

This study compares the effect of the white mineral trioxide aggregate (WMTA) accelerators including disodium hydrogen orthophosphate (Na2HPO4) (2.5 wt%), calcium chloride (CaCl2) (5 wt% and 10 wt%), and KY jelly, on the push-out bond strength of WMTA. The null hypothesis was that the WMTA accelerators would not affect the push-out strength of WMTA.

Physical Activity and Cognitive Function Among Older Adults with an Elevated Gamma Gap.

We evaluated whether gamma gap is associated with cognitive function among older adults and whether physical activity is favorably associated with cognition among those with an elevated gamma gap. Materials (Subjects) and MethodsData from the 1999-2002 NHANES were used to identify 2,352 older adults, ages 60-85. The gamma gap was evaluated from subtracting albumin from total protein (i.e., Gamma Gap = Total Protein (g/dl) - Albumin (g/dl). Those at or above 3.1 g/dl (31.0 g/L) were considered to have an el...

Reply to the Comment Entitled "Martin Method for Estimation of Low-Density Lipoprotein Cholesterol".

Comparison of Pain Characteristics in Patients with Rheumatoid Arthritis and Systemic Sclerosis with Particular Reference to Neuropathic Pain Component: Cross-Sectional Study.

To compare characteristics of pain in terms of neuropathic pain and to assess association between neuropathic component and quality of life (QoL) in patients with systemic sclerosis (SSc) and rheumatoid arthritis (RA).

Combined Enteral and Parenteral Glutamine Supplementation in Endotoxaemic Swine: Effects on Portal and Systemic Circulation Levels.

To measure plasma GLN levels in systemic and portal circulation after combined enteral and parenteral administration in early endotoxemic swine. We hypothesized that this combination will be more efficient than intravenous alone in restoring plasma levels during the course of endotoxemia.

Decreased Spexin Levels in Patients with Type 1 and Type 2 Diabetes.

Spexin is a novel peptide which has a potential role as a biomarker of insulin resistance, diabetes and obesity. We aimed to measure levels of spexin in lean type 1 diabetic patients and its relevance to glycemic parameters without the presence of obesity or insulin resistance.

Rapid and Accurate Identification of Candida albicans and Candida dubliniensis by Real-time PCR and Melting Curve Analysis.

Candida albicans and Candida dubliniensis are germ tube-positive pathogenic yeast species. Accurate identification of these two species is warranted since C. albicans is a highly pathogenic species while C. dubliniensis exhibits increased adherence to buccal epithelial cells, reduced susceptibility to azoles and resistance to flucytosine. We have developed a duplex real-time PCR assay for rapid detection and differentiation between clinical C. albicans and C. dubliniensis isolates.

Impact of Brief Exposure to Drugs with Antifungal Properties on the Susceptibility of Oral Candida dubliniensis Isolates to Lysozyme and Lactoferrin.

Lysozyme and lactoferrin have anti-candidal activity. Candida dubliniensis is associated with oral candidiasis. Candida infections are managed with nystatin, amphotericin B, caspofungin, ketoconazole, fluconazole and chlorhexidine. Candida undergo a brief exposure to therapeutic agents in the mouth. There is no data on the influence of limited exposure to antimycotics on the sensitivity of C. dubliniensis to lactoferrin and lysozymes. Hence, this study observed the changes in the sensitivity of C. dublinien...

Sauna Bathing and Risk of Psychotic Disorders: A Prospective Cohort Study.

Sauna bathing has been suggested to promote mental well-being and relaxation, but the evidence is uncertain with respect to mental disorders. We aimed to assess the association of frequency of sauna bathing with risk of psychosis in the Kuopio Ischemic Heart Disease prospective population-based study.

Rheumatoid Arthritis: A Brief Overview of the Treatment.

Rheumatoid arthritis (RA) is a chronic inflammatory systemic autoimmune disease, affecting the joints with varying severity among patients. The risk factors include age, gender, genetics and environmental exposure (cigarette smoking, air pollutants and occupational). Many complications can follow such as permanent joint damage requiring arthroplasty, rheumatoid vasculitis and elty's syndrome requiring splenectomy if it remains unaddressed. As there is no cure for RA, the treatment goals are to reduce the pa...

The Relevance of the Second Cesarean Delivery in the Reduction of Institutional Cesarean Delivery Rates.

The cesarean delivery rate has increased worldwide. The aim of our study was to assess the events associated with the second cesarean deliveries in our institution.

Effect of Strict Volume Control on Renal Progression and Mortality in Non-Dialysis-Dependent Chronic Kidney Disease Patients: A Prospective Interventional Study.

The aim of this study was to examine the effect of volume status on the progressions of renal disease in normovolemic or hypervolemic patients with advanced non-dialysis-dependent CKD who were apparently normovolemic in conventional physical examination.

A Systemic Review on the Prevalence of Atopic Diseases in
Children in the Arabian Peninsula

To study available data on the prevalence of atopic diseases and food allergy in children living on the Arabian Peninsula.

Effect of Celecoxib on Surgical Site Inflammation After Total Knee Arthroplasty: A Randomized Controlled Study.

To evaluate the anti-inflammatory effectiveness of celecoxib and its effect on the rehabilitation of joint function after total knee arthroplasty.

Nontumorous Portal Vein Thrombosis in Liver Cirrhosis: Possible Role of β-Blockers


Non-selective β-blockers (NSBBs) are used in liver cirrhosis (LC) to prevent variceal bleeding because they decrease portal pressure. A main risk factor for the development of portal vein thrombosis (PVT) in LC is decreased portal vein inflow velocity. The aim of our study was to examine retrospectively the incidence of PVT and its correlation with the use of β-blockers in a cohort of LC patients.

Martin Method for Estimation of Low-Density Lipoprotein Cholesterol.

No Abstract.

Opioids and Cardiac Arrhythmia: A Literature Review.

One of the most important side effects of opioids is their influence on the electrical activity of the heart. This review focusses on the effects of opioids on QT interval prolongation and their arrhythmogenic liability.

A New Technique to Induce Experimental Myointimal Hyperplasia.

Arterial myointimal hyperplasia (MIH) has a significant impact on long-term outcomes of vascular procedures such as bypass surgery and angioplasty. In this study, we describe a new and innovative technique to induce MIH by using a dental flossing cachet in Wistar rats.

Reply to the Comment Entitled "Association of FTO rs9939609 with Obesity".

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