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The US National Library of Medicine and National Institutes of Health manage PubMed.gov which comprises of more than 21 million records, papers, reports for biomedical literature, including MEDLINE, life science and medical journals, articles, reviews, reports and books. BioPortfolio aims to publish relevant information on published papers, clinical trials and news associated with users selected topics.
For example view all recent relevant publications on Epigenetics and associated publications and clincial trials.
Diabetic complications involve multiple pathological pathways, including hyperglycemia-induced oxidative stress and inflammation. Combination therapy is usually employed to improve treatment outcomes and to lower potential adverse effects. In this study, we evaluated the effects of antidiabetic and antihypertensive agents, glibenclamide (GLI) and losartan (LT), on diabetes-associated metabolic changes in rats.
To describe a rare case of Blue Rubber Bleb Nevus (BRBNS) with growth retardation and pubertal delay.
To investigate the influence of sleep apnea on ECG and blood pressure monitoring parameters in patients with acute heart failure (AHF).
Nutraceuticals are advertised and sold with the label claim of being natural and safe herbal products. Due to the absence of clear regulations and guidelines for safety assessments of these products, nutraceuticals are commonly adulterated in order to increase sales. The objective of the current study was to design a comprehensive evaluation system to assess the safety, efficacy, authenticity according to label claim and pharmaceutical quality, of herbal slimming products in between 2015 and 2017.
This cross-sectional survey aimed to assess the knowledge of dentists and dental assistants practicing in Saudi Arabia, regarding diabetes mellitus (DM) and periodontal diseases.
Aortic arch calcification is a surrogate marker for arterial stiffness and hypertension-related vascular damage. Renal Resistive Index, a renal Doppler ultrasound parameter, is used to assess renal hemodynamics. In this study, the authors aimed to evaluate the relationship between Renal Resistive Index and aortic arch calcification in patients with hypertension.
To investigate the sensitivity and specificity of dig¬ital mammography (DM) and digital breast tomosynthesis (DBT) for the detection of breast cancer in comparison to histopathology findings.
The common thread running through all forms of sexual objectification is the experience of being treated as a body (or collection of body parts) valued predominantly for its use to (or consumption by) others. Girls and women who adopt a peculiar view of self, an effect called self-objectification may contribute to women's depression, sexual dysfunction, and eating disorders. The objectives of the study are to investigate the impact of modesty (in terms of veiling, i.e. hijab) on objectification, by others a...
In this study, we aimed to determine the predictive value of the CHA2DS2VASc score for acute stent thrombosis (ST) in patients with an ST elevation myocardial infarction (STEMI) treated with a primary percutaneous coronary intervention (pPCI).
In establishing an evidence-based rationale for the optimal use of implant therapy in patients with type 2 diabetes mellitus (T2DM), it is essential to first understand the impact of glycemic control on early healing and the success of dental implants. The objective of this study was to evaluate crestal bone loss (CBL) and stability around submerged and non-submerged dental implants in Saudi patients with well- and poorly-controlled type 2 diabetes mellitus (T2DM).
Cardiac syndrome X (CSX) is defined as angina-like symptoms, abnormalities on stress testing and normal epicardial coronary arteries on coronary angiography. The aim of this study was to determine the Hospital Anxiety and Depression scores of patients with CSX and to compare with healthy controls. Materials/Subjects and Methods: Patients undergoing coronary angiography between January 2015 and December 2016 because of clinical indications, including abnormal noninvasive test results were examined. Two hundr...
The aim of this study was to determine whether an early increase in intracranial pressure (ICP) following the deflation of a tourniquet is related to the tourniquet time (TT) or tourniquet pressure (TP) and to identify a safe cutoff value for TT or TP.
Third molar impaction is seen much more than impaction of any other tooth as they are the last teeth to erupt. Inadequate retromolar space and the direction of eruption may be contributing factors. The aim of this study was to investigate the relationship between third molar impaction and different skeletal face types.
Acute thrombotic occlusion of >1 major coronary arteries is very rare (2.5%). Herein, we report a patient with simultaneous anterior and inferior myocardial infarction without cardiogenic shock.
To present a case of relapsing and resistant Sweet's syndrome that developed during pregnancy together with an onset of Crohn's disease, showing complete resolution with the use of infliximab.
To present a case of colopathy related to the use of diclofenac in a patient with a positive immunochemical faecal occult blood test (iFOBT) with a view to discuss the influence of non-steroidal anti-inflammatory (NSAID) agents on iFOBT specificity.
Pseudomonas aeruginosa and Staphylococcus aureus dual species biofilm infections are notoriously difficult to manage. This study was aimed at investigating the influence of four different culture media on the planktonic growth, adhesion and biofilm formation of Pseudomonas aeruginosa and Staphylococcus aureus.
To present case of a child with epididymal dirofilariasis.
Sudden sensorineural hearing loss (SNHL) is a common acute disease with an incidence of 0.5-2/10,000. This study aimed to determine whether neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) could be indicators for sudden sensorineural hearing loss (SNHL).
Intracranial tumors are one of the most frightening and difficult to treat tumor types. In addition to surgery, additional protocols such as chemotherapy and radiotherapy also take place in the treatment. Glutathione S-transferase (GST) and cytochrome P450 (CYP) enzymes are prominent drug metabolizing enzymes in human body. The aim of the present study is to show the expression of GSTP1, GSTM1, CYP1A1 and CYP1B1 in different types of brain tumors and to compare the results with current literature.
Dementia is one of the most common neurodegenerative disorder among older populations around the world, and the incidence is increasing. Many epidemiologic studies have considered the association between proton-pump inhibitors and dementia, yet the relationship is still controversial.The objective of this study was to validate whether or not proton-pump inhibitors is indeed associated with dementia.Materials (Subjects) and Methods: We searched for articles on clinical studies of dementia and proton pump inh...
To report on a case of intravesical explosion during transurethral resection of prostate (TURP) which was managed laparoscopically and to review the relevant literature.
Sinus floor evelation and augmentation surgery is widely used as a reliable procedure to increase insufficient bone height in the posterior maxillary area. The purpose of the present clinical study was to determine the associations between periodontal bone loss (PBL), maxillary sinus lateral bone wall thickness, age, and gender using cone beam computerized tomography (CBCT).
Polycystic ovary syndrome (PCOS) is a serious endocrine disorder. In the present study, we investigated the therapeutic effects of erdosteine in letrozole induced-PCOS in rats. Methods: Thirty two wistar albino female rats were grouped as control group (C), PCOS group (PCOS), PCOS-metformin group (PCOS+MET), PCOS-erdosteine group (PCOS+Erd). Polycystic ovary syndrome was induced by administering letrozole; such rats presented with sex hormone disorder, abnormal estrous cycles determined by daily vaginal sme...
Patients with Turner syndrome (TS) have an unfavorable cardiometabolic profile. Hyperhomocysteinemia is a potential cardiovascular risk factor influenced by genetic and environmental factors, therapies, unbalanced diets and other lifestyle factors. We retrospectively studied the relationship between total plasma homocysteine (Hcy), serum vitamin B12 (B12) and folate concentration (s-F) in TS patients, taking into account the genetic profile, diet, smoking habits, hormonal therapies and dietary supplements o...