Track topics on Twitter Track topics that are important to you
The US National Library of Medicine and National Institutes of Health manage PubMed.gov which comprises of more than 29 million records, papers, reports for biomedical literature, including MEDLINE, life science and medical journals, articles, reviews, reports and books.
BioPortfolio aims to cross reference relevant information on published papers, clinical trials and news associated with selected topics - speciality.
For example view all recent relevant publications on Epigenetics and associated publications and clincial trials.
Microparticles (MPs) are shed extracellular vesicles that express the pro-thrombotic tissue factor (TF). Aerobic exercise may reduce MP count and TF expression. This study investigated the impact of acute running or rest followed by standardised meal consumption on MP phenotypes and TF expression.
Establish the true influence of spinal cord injury (SCI) level on core temperature and sweating during exercise in the heat independently of biophysical factors.
Spinal cord injury (SCI) negatively impacts muscle quality and testosterone levels. Resistance training (RT) has been shown to increase muscle cross-sectional area (CSA) following SCI, while testosterone replacement therapy (TRT) has been shown to improve muscle quality in other populations. The purpose of this pilot study was to examine if the combined effects of these interventions, TRT+RT, may maximize the beneficial effects on muscle quality after SCI.
Large inter-individual variation exists in maximal fat oxidation rates (MFO) and the exercise intensity at which it occurs (FATMAX). However, there is no data describing the shape of the fat oxidation curve or, if individual differences exist when tested on separate occasions. Furthermore, there is limited data on fat metabolism in professional team sport athletes. Therefore, the aim of this study was to test-retest the concavity (shape) and intercept (height) of fat oxidation curves within a group of profe...
Concussions are common in military personnel and may result in increased risk of musculoskeletal injury. One plausible explanation for this risk could be that neuromotor deficiencies enhance injury risk following concussion through altered muscular activation/contraction timing.
Identifying promoters of cerebral small vein integrity is important to counter vascular contributions to cognitive impairment and dementia.
To examine the degree of neuromuscular fatigue development along with changes in muscle metabolism during two work-matched high-intensity intermittent exercise protocols in trained individuals.
Interest in a variety of physical behaviors (e.g., exercise, sitting time, sleep) in relation to health outcomes creates a need for new statistical approaches to analyze the joint effects of these distinct but inter-related physical behaviors. We developed and tested an integrated physical behavior score (PBS).
We aimed to measure 1) the dynamics of locomotor fatigue during constant supra-critical power cycling, and 2) the magnitude of any reserve in locomotor power at intolerance to constant and ramp-incremental cycling in recreationally-active volunteers.
Breaking the sub-2 hour marathon in an official event has attracted growing interest in recent times with commercial and international momentum building. Here it is shown that predicting how likely, and when, the sub-2 hour barrier will be broken are statistically coupled considerations.
Automobile racing is widely known to be physically demanding, however there is no published information comparing the physical fitness variables of elite level race car drivers across various competitive championships.
Vertebral fractures reduce the quality of life and are a major burden to the health care sector. Small vertebral size is associated with increased vertebral fracture risk. Previous studies have investigated the relationship between physical activity and vertebral size, but their results seem somewhat contradictory. In this population-based birth cohort study, we aimed to evaluate the relationship between objectively measured physical activity (PA) and vertebral size.
Static stretching (SS) has been used for inducing acute and long-term increases in range of motion (ROM). Foam rolling (FR) has recently gained popularity for acutely increasing ROM. However, the long-term effects of FR on ROM have not been thoroughly evaluated. Therefore, the purpose of this study was to investigate the acute and long-term changes in dorsiflexion range of motion (ROM) as a result of six weeks of FR, SS, and FR followed by SS (FR + SS).
High vertical ground reaction force (vGRF) loading rates are thought to contribute to lower extremity injuries in runners. Given that elevated lower extremity stiffness has been reported to be associated with increased GRFs, the purpose of the current study was to determine if overall lower extremity stiffness, or individual joint angular excursions and/or torsional stiffness are predictive of the average vGRF loading rate during running.
The physiological consequences of freely chosen cadence (FCC) during cycling remains poorly understood. We sought to determine the effect of cadence on the respiratory and hemodynamic response to cycling exercise.
Strategies that underload the surgical limb following anterior cruciate ligament reconstruction (ACLr) are observed in submaximal tasks. It is not known what underlies these strategies in early rehabilitation. The purpose of this study was to determine if underloading can be attributed to the inability to meet task demands with and without attention to limb loading or learned behavior.
Cerebrovascular disease in the form of white matter hyperintensities (WMH) increases with age and is associated separately with sedentary time and reduced kidney function. A better understanding of the relationships among these variables would help clarify whether sedentary time should be considered more closely in older adults at particular levels of kidney function to reduce the risk of WMH.
To determine the effects of exercise during pregnancy on the neuromotor development of one-month old offspring. We hypothesized that aerobic exercise during pregnancy would be associated with higher neuromotor scores in infants at one month of age, based on standard pediatric assessment of neuromotor skills.
Physical exercise or hypoxic exposure influences erythrocyte susceptibility to osmotic stress, and the aquaporin 1 (AQP1) facilitates the transport of water in erythrocytes. This study investigated whether high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) affect erythrocyte osmotic deformability by modulating AQP1 function under hypoxic stress.
Exercise is well-known to enhance a variety of mood states, but few studies have been specifically designed to investigate whether acute aerobic exercise alters feelings of anger. The goal of this study was to determine the magnitude of the effects of acute exercise on both angry mood and angry emotions.
Ageing is associated with impaired cerebral blood flow (CBF) and increased risk of cerebrovascular disease. Acute increases in CBF during exercise may initiate improvements in cerebrovascular health, but the CBF response is diminished during continuous exercise in older adults. The effect of interval exercise for promoting increases in CBF in young and old adults is unknown.
Energy expenditure of resistance exercise (RE) is an important consideration for exercise prescription and weight management, yet prediction models are lacking.