PubMed Journal Database | Psychosomatic medicine RSS

02:44 EST 12th December 2018 | BioPortfolio

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Showing PubMed Articles 1–25 of 279 from Psychosomatic medicine

Depressive symptoms during childhood and cardiovascular risk factors in black and white men.

Depressive symptoms and major depression predict cardiovascular disease (CVD) and CVD risk factors in adulthood. Evidence regarding the role of depression in the development of CVD risk in youth is minimal. The study evaluated the prospective relationship of depressive symptoms in childhood and adolescence with adult CVD risk factors in black and white men.

Association between endothelial function and cognitive performance in patients with coronary artery disease during cardiac rehabilitation.

Subtle cognitive deficits indicating early neural risk are common in the clinical presentation of coronary artery disease (CAD). Although deterioration may be mitigated by exercise, cognitive response to exercise is heterogeneous. Vasculopathy including endothelial dysfunction, is a hallmark of CAD and may play an important role in impairing neural adaptation to exercise. This study aimed to assess peripheral measurements of endothelial function as predictors of cognitive performance in CAD participants und...

Altered Hypothalamus-Pituitary-Adrenal Axis Function: A Potential Underlying Biological Pathway for Multiple Concurrent Symptoms in Patients with Advanced Lung Cancer.

Patients with advanced cancer commonly experience multiple symptoms that present as groups or clusters. The present study aimed to examine whether hypothalamus-pituitary-adrenal (HPA) axis dysfunction underlies the concurrent multiple symptoms in patients with advanced cancer.

Longitudinal associations between inflammation and depressive symptoms in chronic dialysis patients.

Patients undergoing chronic dialysis often display sustained elevations of inflammation markers and also have a high prevalence of depressive symptoms. Although multiple studies demonstrated cross-sectional associations between inflammation markers and depressive symptoms in this patient group, longitudinal associations have not been examined. We therefore investigated whether longitudinal associations exist between inflammation markers and depressive symptoms in chronic dialysis patients.

Marriage and Gut (Microbiome) Feelings: Tracing Novel Dyadic Pathways to Accelerated Aging.

Couples influence each other's mental and physical health. This review focuses on how couples' relationships, the partners' individual and joint vulnerabilities, and their health behaviors influence health through changes in the gut microbiota, metabolism, and immune function. Couples' shared stressors and emotions and their intertwined lifestyles and routines serve to promote common disease risks in part through parallel changes in their gut microbiotas. Marital discord, stress, and depression have strong ...

Computerized exposure therapy for Spider Phobia: Effects of cardiac timing and interoceptive ability on subjective and behavioral outcomes.

Spider phobia is a common form of anxiety disorder for which exposure therapy is an effective first-line treatment. Motivated by the observed modulation of threat processing by afferent cardiac signals; we tested the hypothesis that interoceptive information concerning cardiovascular arousal can influence the outcomes of computerised exposure therapy for spider phobia.

Bereavement, self-reported sleep disturbances and inflammation: Results from Project HEART.

Spousal bereavement is linked to increased mortality and morbidity from inflammatory conditions. It also has a significant impact on sleep disturbances. Evidence from experimental studies indicates that chronic stress may prime individuals to have an exaggerated inflammatory response to acute stress. In this study, we examined the association between self-reported sleep disturbances and inflammation after adjusting for depressive symptoms, and determined whether this association varies by bereavement status...

Article Summaries for October 2018 Psychosomatic Medicine, Volume 80, Issue 8.

Biased Competition Favoring Physical Over Emotional Pain: A Possible Explanation for the Link Between Early Adversity and Chronic Pain.

Early adversity predisposes to chronic pain, but a mechanistic explanation is lacking. Survivors of early adversity with chronic pain often appear impaired in their ability to be aware of, understand, and express distressing emotions such as anger and fear in social contexts. In this context, it has been proposed that pain may at times serve as a "psychic regulator" by preventing awareness of more intolerable emotions.

The effect of traditional Chinese medicine Zhike-Houpu herbal pair (ZKHPHP) on depressive behaviors and hippocampal serotonin 1A receptors in rats following chronic unpredictable mild stress (CUMS).

Zhike-Houpu herbal pair (ZKHPHP) is a well-known Chinese medicine to treat gastrointestinal motility dysfunction. Recently, many researchers have found that some of the compounds of ZKHPHP such as meranzin hydrate and magnolol have antidepressant effects. However, little is known about the antidepressant mechanism of ZKHPHP. Therefore, the main aim of the study is to evaluate the antidepressant-like effects of ZKHPHP and its possible mechanism of action on HTR1A (5-hydroxytryptamine receptor 1A) in the hipp...

Article Summaries for September 2018 Psychosomatic Medicine, Volume 80, Issue 7.

Neural Correlates of Giving Social Support: Differences between Giving Targeted versus Untargeted Support.

Giving support contributes to the link between social ties and health, however, the neural mechanisms are not known. Giving support in humans may rely on neural regions implicated in parental care in animals. The current studies, therefore, assess the contribution of parental care-related neural regions to giving support in humans and, as a further theoretical test, examine whether the benefits of giving targeted support to single, identifiable individuals in need extends to giving untargeted support to lar...

Intimacy as related to cortisol reactivity and recovery in couples undergoing psychosocial stress.

The importance of recovery from stress is evident in times of high prevalence of stress-related diseases. Intimacy has been found to buffer psychobiological stress-reactivity, suggesting that emotional and physical closeness might trigger biological mechanisms which underlie the health-beneficial effects of couple relationships. Here we investigated whether couples' spontaneous expression of intimacy before and after psychosocial stress exposure in the laboratory reduced cortisol reactivity and accelerated ...

Reduced Fear-Conditioned Pain Modulation in Experienced Meditators: A Preliminary Study.

Mindfulness-based practice is a form of cognitive/affective training that may help reduce suffering by attenuating maladaptive anticipatory processes. This study's objective was to examine the pain modulating impact of classical fear learning in meditation practitioners.

Prevalence of Illness-Induced Posttraumatic Stress Disorder in the United States.

Comparison of Treatment Rates of Depression After Stroke Versus Myocardial Infarction. A Systematic Review and Meta-Analysis of Observational Data.

Depression after stroke and myocardial infarction are common but often assumed to be undertreated without reliable evidence being available. Thus, we aimed to determine treatment rates and investigate the application of guidelines in these conditions.

Insecure Attachment and Hypothalamus-Pituitary Adrenal Axis Functioning in People with Eating Disorders.

Childhood attachment experiences affect adult emotion regulation and ability to cope with stressors. Therefore, insecure attachment may influence the functioning of the hypothalamic-pituitary-adrenal (HPA) axis and a dysregulation of HPA axis has been found in insecure attached healthy individuals. The effects of attachment on HPA axis activity have never been investigated in eating disorders (EDs). Therefore, we assessed the relationships between insecure attachment and the cortisol awakening response (CAR...

Food insecurity and odds of high allostatic load in Puerto Rican adults: the role of participation in the Supplemental Nutrition Assistance Program (SNAP) during 5 years of follow-up.

Limited evidence demonstrates pathways linking food insecurity (FI) to chronic disease. Allostatic load (AL) may elucidate potential pathways, capturing both primary (neuroendocrine, inflammation) and secondary (metabolic, cardiovascular) physiological disturbances. We examined the longitudinal association of FI with 5-year AL and primary and secondary sub-system dysregulation, and tested moderation by Supplemental Nutrition Assistance Program (SNAP) participation.

Psychosocial stress over the lifespan, psychological factors, and cardio-metabolic risk in the community.

The complex relationship between psychosocial stress over the lifetime, psychological factors, and cardio-metabolic risk is still poorly understood. Accordingly, our aims were 1) to independently assess the associations between childhood adversity, life-event stress in remote (earlier than the last 5 years) and recent adulthood and cardio-metabolic risk, and 2) to determine the role of psychological factors including personality, coping and depression in these associations.

The role of norepinephrine and alpha-adrenergic receptors in acute stress-induced changes in granulocytes and monocytes.

Acute stress induces redistribution of circulating leucocytes in humans. Whereas effects on lymphocytes as adaptive immune cells are well-understood, the mechanisms underlying stress effects on granulocytes and monocytes as innate immune blood cells are still elusive. We investigated whether the stress hormone norepinephrine (NE) and α-adrenergic receptors (α-ADRs) may play a mediating role.

From anticipation to the experience of pain: The importance of visceral versus somatic pain modality in neural and behavioral responses to pain-predictive cues.

The aim of this study was to compare behavioral and neural anticipatory responses to cues predicting either somatic or visceral pain in an associative learning paradigm.

Subjective Age and Mortality in Three Longitudinal Samples.

Subjective age has been implicated in a range of health outcomes. The present study extends existing research by providing new data on the relation between subjective age and mortality in three large national samples.

Anticipatory effects on perceived pain: Associations with development and anxiety.

Naturalistic studies suggest that expectation of adverse experiences such as pain exerts particularly strong effects on anxious youth. In healthy adults, expectation influences the experience of pain. The current study uses experimental methods to compare the effects of expectation on pain among adults, healthy youth, and youth with an anxiety disorder.

Exploring the Association of Hypertension with Risk for Depression: Evidence for Tamed Neurobehavioral Arousal versus Central Emotional Dysregulation.

Depression is an established predictor of adverse cardiovascular disease outcomes. Less is known about cardiovascular risk factors as predictors of depression. In this issue of Psychosomatic Medicine, Patel et al. report data indicating that pre-existing hypertension may be associated with the atypical but not typical form of depression. We highlight here the strengths and limitations of the article and discuss the findings in light of research linking blood pressure and emotion regulation. In general, evid...

Article Summaries for June 2018 Psychosomatic Medicine, Volume 80, Issue 5.

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