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09:19 EST 27th February 2020 | BioPortfolio

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Showing PubMed Articles 1–25 of 207 from Revista peruana de medicina experimental y salud publica

Venezuelan immigration in Peru from a health perspective.

Quality of life of venezuelan migrants in two cities in northern Peru.

To describe the health-related quality of life (HRQoL) of Venezuelan migrants residing in the cities of Chimbote and Nuevo Chimbote, in Peru, and assess its associated factors.

River boats as a means of expansion of Aedes aegypti towards border zones of the peruvian amazon.

To assess the entomological risk of Aedes aegypti in boats traversing border river routes in Loreto.

Text messaging to improve patient adherence in haart: randomized controlled trial.

To assess the efficacy of a text messaging (SMS) strategy to improve appointment attendance, treatment adherence, and biological markers (viral load and CD4) in continuous patients with high activity antiretroviral therapy (HAART) who were late to their last scheduled appointment.

Concordance of the assessment of pubertal development with the Tanner scale between adolescents and a trained physician.

To assess the concordance between self-assessment of pubertal development with the Tanner scale performed by adolescents compared to the assessment performed by a trained physician.


To design and assess a multiepitopic protein as a candidate for a vaccine against Carrion disease.

Comparison of methods of DNA extraction from Giardia spp. measured by conventional PCR.

To compare different methods of DNA extraction from cysts and trophozoites of Giardia spp. using the conventional polymerase chain reaction (PCR) technique.

Factors associated with survival at one year of life in neonates with severe congenital cardiopathy in A National Hospital in Peru.

To determine factors associated with survival in the first year of life in neonates with severe congenital heart disease treated in a national hospital in Peru.

Development and validation of loop-mediated isothermal amplification for the detection of the Zika virus.

A Reverse Transcription Loop-mediated Isothermal Amplification (RT-LAMP) method was developed to detect Zika. The primers were designed based on the NS5 region of 64 complete genomes. Lyophilized LAMP reagent was used. Initially, seven different arboviruses were tested and only Zika samples tested positive. Additionally, serial dilutions of one of Zika's RNA were compared using RT-LAMP and qRT-PCR, demonstrating that RT-LAMP is 1,000 times more sensitive. We also evaluated 300 serum samples with RT-LAMP com...

Intraventricular hemorrhage and periventricular leukomalacia in low birth-weight neonates in three hospitals in Lima, Peru.

To describe the frequency and severity of intraventricular hemorrhage and periventricular leukomalacia in low birth-weight neonates in three hospitals in Lima, Peru, 385 newborn babies weighing under 2,000 g at birth were evaluated between May 2012 and July 2014. Brain ultrasounds were obtained at 40 weeks' gestation, 3-5 days of life, and 3-4 weeks of life. Intraventricular hemorrhage occurred in 19.2% of neonates weighing under 1,500 g and was severe (grade III or with periventricular hemorrhagic infarcti...

Lymphocyte population count as a first approach to the diagnosis of primary immunodeficiencies.

Primary immunodeficiencies (PID) are characterized by alterations in the components of the immune system. The lymphocyte population count by flow cytometry is an approach to molecular diagnosis and is expressed by immunophenotypes. The objective of the study was to describe the lymphocyte population count and immunophenotyping compatible with PID in patients with suspected PID in a Peruvian national reference hospital. Records of 261 cases meeting the Jeffrey Modell Foundation's PID clinical suspicion crite...

Antimicrobial resistance of commensal Escherichia coli strains in children of two rural communities in Peru.

Antibiotic resistance is a major global problem. The objective of this study was to determine antibiotic resistance in commensal strains isolated from healthy children from rural communities of Moyobamba and Urubamba in Peru. This cohort study identified 179 commensal E. coli strains from 93 children, followed for six months. Thirteen antibiotics were analyzed by diffusion disk. The highest rates of resistance were for cotrimoxazole (49.1%), ampicillin (48.0%), and nalidixic acid (31.8%). An 11.6% increase ...

Invasive salmonellosis in a hospital in Lima, Peru.

The study's objective was to determine the epidemiological, clinical, and laboratory characteristics of cases of invasive salmonellosis and the antibiotic susceptibility profile of salmonella isolates (2013-2017), in a series of cases of patients with Salmonella spp. isolated from secretions and/or body fluids with or without positive stool culture (n=70). For the evaluation of antibiotic susceptibility, the first isolate was considered in all cases of salmonellosis (n=168). The highest frequency of cases o...

Performance assessment in microscopic diagnosis of malaria in the laboratory network of the National Institute of Health of Peru, 2012-2017.

Timely diagnosis of malaria is a strategy proposed by the World Health Organization to reduce malaria morbidity and mortality. A study was conducted to assess performance in microscopic diagnosis of malaria in the network of laboratories under the National Malaria Reference Laboratory of the National Institute of Health between 2012 and 2017. In the years of study, the laboratories obtained a rating of "acceptable" in the diagnosis of Plasmodium by 38.4%, 43.7%, 60.0%, 83.3%, 90.9%, and 95.8%, respectively,...

Detection of mutations causing Duchenne and Becker muscular dystrophies: multiplex polymerase chain reaction vs. Multiplex ligation dependent probe amplification.

Duchenne and Becker muscular dystrophies are rare diseases that receive limited attention in our field. The objective of this study was to implement the Multiplex Ligation-dependent Probe Amplification technique (MLPA) and to demonstrate that it has advantages over the Multiplex Polymerase Chain Reaction (Multiplex PCR) technique. Samples from 40 individuals with a presumptive diagnosis of Duchenne and Becker muscular dystrophies were analyzed: first by Multiplex PCR and then by MLPA. Fifteen individuals wi...

Beliefs and attitudes of health workers and nursing students toward an influenza pandemic in a region of Spain.

A survey was carried out during March-May 2017 to analyze the beliefs and attitudes of health workers and nursing students in the face of an influenza pandemic in Las Palmas de Gran Canaria, Spain. A high percentage doubted that there is a vaccine to protect them against an influenza pandemic, although workers showed greater certainty than students concerning access to a vaccine. Health workers showed themselves as more responsible for their work than students; i.e., 46.7% would be in favor of penalizing an...

Health of international migrants in an irregular situation: a narrative review of initiatives.

The population of international migrants in an irregular situation (IMIS) often finds itself in a condition of particular vulnerability that has an impact on its health. Additionally to this, these migrants face multiple barriers that hinder or even impede their access to health services. This review aims at identifying and describing initiatives that address access to health services in the IMIS population. To this end, a narrative review was conducted in PubMed, Embase, Health Systems Evidence, Cochrane, ...

Venezuelan immigration in Peru: challenges and opportunities from a health perspective.

As a result of the political, social, and economic crisis in the Bolivarian Republic of Venezuela, more than 700,000 people have immigrated to Peru since the second semester of 2017. In the year following the 2017 census, Peru's population grew by nearly one million, some 300,000 of them Peruvian, the rest being predominantly young Venezuelan immigrants. This article describes and analyzes the situation and health implications stemming from the fact that Peru became a migratory destination. To this end, a s...

Nutritional situation of venezuelan migrant children upon entry into Peru and the actions taken to protect their health and nutrition.

The high level of Venezuelan migration is a great challenge for Peru due to the healthcare needs of immigrants. Worryingly, children under the age of five are the most vulnerable. In order to know the nutritional status of this group in migratory transit to Peru, a descriptive study was carried out with two rounds of data collection (August 2018 and March 2019) at the Binational Border Healthcare Center in Tumbes. In each round, nutritional status, morbidity and food characteristics were determined for 322 ...

Surveillance, prevention, and control of influenza virus in Peru.

The importance of surveilling the circulation of the influenza virus and timely vaccination of different populations in Peru was analyzed in three sessions by a group of clinical experts from different specialties. The Peruvian national influenza surveillance system has many selected establishments that have become currently ineffective in terms of a timely report. Most of the samples come from Lima. The viral distribution is inadequately analyzed. The northern and jungle areas of the country have weather a...

Rapidly fatal septicemic plague secondary to undiagnosed primary bubonic plague: case report.

Plague is a re-emerging disease caused by the bacteria Yersinia pestis. Humans usually get the disease through the bite of an infected flea. Plague is a fulminant systemic disease, with pneumonic plague being the most lethal form. Late diagnosis is one of the main causes of mortality and spread of the disease, as it limits the effectiveness of control measures. We present the case of a 42-year-old male, who had previously traveled to an endemic plague area and then presented hyperpyrexia, hypotension, and i...

Malaria in HIV-Infected patients: a series of cases in a peruvian hospital.

The clinical signs of malaria in HIV patients may vary depending on the immunological status of the patient. Nationally, evidence regarding co-infection is scarce. This research describes four cases from a hospital in Iquitos, Peru, of patients diagnosed with HIV infection and a positive blood test for malaria. Two of these patients had Plasmodium falciparum infection, and two had Plasmodium vivax infection. One of the patients was in the AIDS stage with poor adherence to combination antiretroviral therapy ...

Cutaneous metastasis of prostate adenocarcinoma: a case report.

Cutaneous metastases are very rare events and are related to a distant tumor invasion. Prostate metastases have a 1% appearance rate; the most common locations include the genital or suprapubic region and are very rarely located at a distance. We report the case of a male patient with cutaneous metastasis of prostate adenocarcinoma located in the cervical and upper thoracic area. The patient also had a history of pulmonary tuberculosis. A CT scan revealed the presence of bone metastasis, pleural effusion, a...

From Claude Bernard to Telémaco Battistini: experimental medicine in the birth of the Scientific Journal of the Peruvian National Institute of Health.

The Peruvian Journal of Experimental Medicine and Public Health (RPMESP) was first published in 1942 under the name Journal of Experimental Medicine. Since then, it has been the official scientific dissemination vehicle of the Peruvian National Institute of Health, which was founded in 1936. Telémaco Battistini Sánchez was directly involved in both historical events. Based on some passages of his personal history and on the historical juncture of global and Latin American science between 1865 and 1950, we...

Leptospirosis in patients with negative results for dengue, zika, and chikungunya in Jaen, Peru.

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