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PubMed Journal Database | The American journal of drug and alcohol abuse RSS

13:58 EST 16th February 2020 | BioPortfolio

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Showing PubMed Articles 1–25 of 138 from The American journal of drug and alcohol abuse

Dialectical behaviour therapy skills training for the treatment of addictive behaviours among individuals with alcohol use disorder: the effect of emotion regulation and experiential avoidance.

: Dialectical behavior therapy skills training (DBT-ST) is an effective treatment for alcohol use disorder (AUD). AUD frequently co-occurs with other addictive behaviors.s: These secondary analyses of prior studies on the effectiveness of a 3-month DBT-ST program for AUD investigated pre- post-treatment changes in the severity of concurrent addictive behaviors. The study hypothesized that emotion regulation and experiential avoidance should be the key therapeutic mechanisms involved in the treatment of addi...

Comparison of drinking prevalence among Thai youth before and after implementation of the Alcoholic Beverage Control Act.

: Underage drinking contributes to numerous health and social problems among adolescents. The Alcoholic Beverage Control Act, issued in Thailand in 2008, contains several clauses aiming at preventing underage and novice drinking, such as raising the minimum legal purchasing age from 18 to 20, banning alcohol sale and consumption in places frequented by youth, and banning alcohol advertisements.: To estimate the changes in the prevalence of alcohol consumption and perceptions of drinking norms among high-sch...

Derivation and assessment of the opioid use disorder severity scale: prediction of health, psychological and social adjustment problems.

Severity of substance use disorder (SUD) is typically evaluated by tabulating the number of symptoms. The resulting estimate of disorder severity is, however, biased due to intercorrelations among symptoms and their unequal salience. . Employing item response theory (IRT) methodology, opioid use disorder symptoms were calibrated to derive the and assess its predictive ability in men and women separately. A two-parameter IRT model was utilized to derive the from symptoms recorded on the (SCID) in 438 men...

Tackling deceptive responding during eligibility via content-knowledge questionnaires.

Gender differences in diversion among non-medical users of prescription opioids and sedatives.

: Non-medical use of prescription drugs is a major public health concern in the United States. Prescription opioids and sedatives are among the most widely abused drugs and their combined use can be lethal. Increasingly rigid prescribing guidelines may contribute to the changing context of opioid use and increase drug diversion.: To examine gender differences in diversion of prescription opioids and sedatives among non-medical prescription opioid and sedative polysubstance users. We hypothesize that men wil...

Outcomes of two quality improvement implementation interventions for depression services in adults with substance use problems.

: Comorbid depression and substance use disorders (SUDs) are associated with poor health and social outcomes disproportionately affecting under-resourced communities.: To test the hypothesis that a coalition approach to collaborative care (CC) for depression would improve outcomes of hazardous drinking and behavioral health hospitalizations, relative to technical assistance, for individuals with comorbid substance use problems. Substance use problems were defined by meeting criteria for DSM-IV substance abu...

Doxazosin treatment in cocaine use disorder: pharmacogenetic response based on an genetic variant.

The α antagonist doxazosin reduces cocaine use in individuals with cocaine use disorder (CUD) through a functional polymorphism of the . The regulatory role of the α () gene polymorphism in CUD is uncharacterized. To study how the genetic variant of gene (T1848A, rs2236554) may affect the treatment efficacy of doxazosin in reducing cocaine use. This 12-week pilot trial included 76 participants with CUD with (T1848A, rs2236554) AA (N = 40) or AT/TT genotype (N = 36). Participants were randomized to d...

The effect of pre-existing alcohol use disorder on the risk of developing posttraumatic stress disorder: results from a longitudinal national representative sample.

: There is inconsistent evidence in the literature as to whether or not Alcohol Use Disorder (AUD) is a risk factor for Post-Traumatic Stress Disorder (PTSD).: We evaluated the risk of developing PTSD after trauma exposure in individuals with AUD. As a secondary analysis, we also tested if alcohol dependence or alcohol abuse separately increased the risk of PTSD development. We also explored the effect of AUD on exposure to various traumas.: Longitudinal data was obtained from 30,180 individuals with and wi...

Increased alcohol preference and intake in nicotine-preferring rats.

Alcohol and tobacco are among the leading substances that are misused together and shared genetic vulnerability is likely. Increased susceptibility to nicotine self-administration has been shown in alcohol-preferring rat-lines. However, a nicotine-preferring (nP) rat-line has not been studied for alcohol preference. To evaluate alcohol preference and intake in male and female nP rats. We hypothesized that nP rats and females would drink more ethanol than control rats and males, respectively. nP rats are bei...

A week-long outpatient induction onto XR-naltrexone in patients with opioid use disorder.

: Extended-release (XR) naltrexone can prevent relapse to opioid use disorder following detoxification. However, one of the barriers to initiating XR-naltrexone is the recommendation for a 7-10-day period of abstinence from opioids prior to the first dose.: The current study evaluated the feasibility of an XR-naltrexone induction protocol that can be implemented over 1 week in the outpatient clinic.: Participants (N = 44) were seen in the clinic daily. On Day 1, after abstaining from opioids for at least 12...

A comparison of blood toxicology in fatalities involving alcohol and other drugs in patients with an opioid use disorder treated with methadone, buprenorphine, and implant naltrexone.

: Methadone, buprenorphine, and implant naltrexone have comparable efficacy in preventing death from drug intoxication during treatment, but there may be differences between treatments in the specific drugs contributing to death and in the risk of death during different phases of treatment.: The objective of this study was to compare concentrations of individual drugs in decedents for evidence that the three medications use to treat opioid use disorders differed in the protection they offered against fatal ...

Patterns of buprenorphine/naloxone prescribing: an analysis of claims data from Massachusetts.

The brand name Suboxone and its generic formulation buprenorphine/naloxone is a medication for treating opioid use disorder. While this medication has been shown to be effective, little research has examined the extent to which it is being prescribed and under what circumstances. This study examined patterns of prescription claims for buprenorphine/naloxone in terms of volume and associated clinical conditions. The study was conducted using a statewide database comprising pharmacy and medical claims that we...

A systematic review of rural-specific barriers to medication treatment for opioid use disorder in the United States.

: Opioid-related deaths have risen dramatically in rural communities. Prior studies highlight few medication treatment providers for opioid use disorder in rural communities, though literature has yet to examine rural-specific treatment barriers.: We conducted a systematic review to highlight the state of knowledge around rural medication treatment for opioid use disorder, identify consumer- and provider-focused treatment barriers, and discuss rural-specific implications.: We systematically reviewed the lit...

How Medicaid work requirements could exacerbate the opioid epidemic.

In 2018, the Trump Administration took the unprecedented step of allowing states to impose work requirements as a condition of Medicaid eligibility. States can apply for a demonstration waiver to require Medicaid beneficiaries aged 19-64 who do not meet exemption criteria (e.g., disability, caring for a sick relative) to participate in "community engagement" activities, which include employment, volunteering, and enrollment in a qualifying education or job training program. Debate thus far has focused prima...

A comparison of frequency of alcohol and marijuana use using short message service surveying and survey questionnaires among homeless youth.

: There are several benefits to using short message service surveying (SMS) to gather data on substance use from homeless youth, including capturing data "in the moment" and verifying the timing of one behavior relative to another. Though SMS is a valuable data collection tool with highly mobile populations that otherwise are difficult to longitudinally sample, the reliability of SMS compared with surveys is largely unknown with homeless youth. Examining the reliability of SMS is important because these dat...

Necessity of addressing motivations for cannabis use to guide research.

Cannabis legalization: progress in harm reduction approaches for substance use and misuse.

The association between regular cannabis use, with and without tobacco co-use, and adverse cardiovascular outcomes: cannabis may have a greater impact in non-tobacco smokers.

: Understanding the potential impact of cannabis use on cardiovascular health is increasingly important as cannabis use rises in the U.S.Objectives: This study evaluated the associations between regular cannabis use, with and without tobacco co-use, and cardiovascular outcomes.: Analysis of a limited dataset obtained through IBM Watson Health Explorys, a platform integrating electronic health record data. Matched controls using Mahalanobis distance within propensity score calipers were defined for: 1) canna...

Effects of attentional bias modification therapy on the cue reactivity and cognitive control networks in participants with cocaine use disorders.

: While attentional bias modification therapy (ABMT) alters drug-related behaviors in some substance users, results have been mixed in individuals with cocaine use disorders (CUD).: The current study examined whether ABMT affected brain functioning during independent measures of cue reactivity (i.e., cocaine versus food cues) and cognitive control (i.e., incongruent versus congruent trials), and whether brain activity was associated with baseline or post-intervention cocaine use.: 37 participants (62% male)...

Implementing social justice in the transition from illicit to legal cannabis.

: The legalization of cannabis for adult use is being increasingly embraced in several countries and local entities. A driving force for these changes has been the individual, family, community, societal, and economic costs of cannabis prohibition, which have fallen most heavily upon disadvantaged minority populations. : In this review, we explore whether the legalization of cannabis has begun to correct the injustices of cannabis prohibition. Progress is assessed in five areas of social justice related to ...

The Desire to Dissociate Scale: factor analysis, cross-cultural findings, and links to substance-induced dissociation.

: Past research identified that a desire for dissociative experiences, rather than dissociative tendencies, mediate the relationship between early sexual abuse and problem drinking in college students. Desire to dissociate was conceptualized as a mechanism facilitating substance-induced dissociation or the use of substances to achieve dissociative-like experiences and was measured using a modified version of the Dissociative Experiences Scale-II. The validity and cross-cultural generalizability of the modif...

Early evidence of the impact of cannabis legalization on cannabis use, cannabis use disorder, and the use of other substances: Findings from state policy evaluations.

The past decade has seen unprecedented shifts in the cannabis policy environment, and the public health impacts of these changes will hinge on how they affect patterns of cannabis use and the use and harms associated with other substances. To review existing research on how state cannabis policy impacts substance use, emphasizing studies using methods for causal inference and highlighting gaps in our understanding of policy impacts on evolving cannabis markets. Narrative review of quasi-experimental studi...

A novel telehealth platform for alcohol use disorder treatment: preliminary evidence of reductions in drinking.

: Alcohol use disorder (AUD) treatment remains greatly underutilized. Innovative strategies are needed to improve AUD treatment access and patient engagement. The Ria Treatment Platform (RTP) is a patient-centered telemedicine AUD treatment program accessed through a smartphone application (app) that includes a package of physician visits (with AUD prescriptions as appropriate), text- and phone-based support from a recovery coach, video monitoring of medication adherence, and Bluetooth-linked breathalyzer t...

The effect of sensation seeking on alcohol use among middle school students: a latent state-trait analysis.

: Sensation seeking has been implicated as a major risk factor for underage alcohol use, however little research into this personality trait has been conducted among children. The current study examined if sensation seeking presents as a state or trait in children, and if the state or trait predicted future alcohol use. : A latent state-trait (LST) analysis was conducted among 552 individuals (54.3% female; age range 8-13; mean age 9.3) to determine the state or trait-based aspects of sensation seeking, an...

Gender differences in unidirectional and bidirectional intimate partner violence in addictions.

Few studies have analyzed the specific characteristics related to uni/bidirectional intimate partner violence (IPV) in patients with addiction problems. Knowing the specific profiles of these patients would allow the development of effective tailored interventions. This study assessed gender differences in unidirectional and bidirectional IPV among patients undergoing drug addiction treatment. We sampled 122 patients (91 male and 31 female) who sought treatment in an addiction treatment center, and collec...


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