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PubMed Journals Articles About "AbbVie Unjustified Humira Settlements Divide Market Claims Class" RSS

10:22 EDT 20th June 2019 | BioPortfolio

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Showing "AbbVie Unjustified Humira Settlements Divide Market Claims Class" PubMed Articles 1–25 of 3,800+

Sustained Long-Term Efficacy and Safety of Adalimumab in Pediatric Patients with Severe Chronic Plaque Psoriasis from a Randomised, Double-Blind, Phase 3 Study.

Adalimumab (Humira , AbbVie Inc, USA) is EMA approved for children ages ≥4 years with severe plaque-psoriasis.


Development and Preliminary Validation of a Medicare Claims-Based Model to Predict Left Ventricular Ejection Fraction Class in Patients With Heart Failure.

Ejection fraction (EF) class is an important predictor of treatment response in heart failure (HF); however, administrative claims databases lack information on EF, limiting their usefulness in clinical and health services research of HF.

Owning Ethical Innovation: Claims about Commercial Wearable Brain Technologies.

The wearable neurotechnology market targets consumers with promises of cognitive benefit and personal wellness. Scientific evidence is essential to substantiate claims about utility, safety, and efficacy and for informed choice and public trust.


A mixed-methods study of women's sanitation utilization in informal settlements in Kenya.

While access to safe sanitation is a global issue, there are large disparities in access. Women living in informal settlements, in particular, are disproportionately affected by lack of access to sanitation. Without adequate sanitation, these women may resort to unsafe strategies to manage their sanitation needs, but limited research has focused specifically on this issue. Qualitative and quantitative data were collected from women in the Mathare informal settlement in Nairobi, Kenya in 2016. A latent class...

Prioritization or unlimited resources in orthopedics and trauma surgery?

The development of the healthcare system in Germany is increasingly approaching human and economic limits. A social consensus and a political concept at which point priorities are promoted and for which services the money should be primarily spent, do not exist on the whole. As soon as it becomes clear that resources are limited and that is now, prioritization has to be introduced to avoid the alternative threat of rationing of treatment benefits. The goal of prioritization is to rationally and optimally ...

PharmaForum AbbVie.

PharmaForum AbbVie.

I like to go out and have a good time: An ethnography of a group of young middle class urban Indian women participating in a new drinking culture.

Urban, middle-class Indians are a market demographic target of transnational alcohol companies seeking to exploit neoliberal-informed deregulation policies. Against this backdrop is an emerging drinking culture in Mumbai, in which women participate.

Guideline-Orientated Prescription of Disease-Modifying Drugs in Patients with Rheumatoid Arthritis - an Analysis Based on Social Health Insurance Claims Data.

 With the market entry of biologics, the treatment of rheumatoid arthritis (RA) has changed fundamentally in terms of efficacy and costs.

Breast cancer medical malpractice litigation in New York: The past 10 years.

Medical error is a leading cause of preventable death in the U.S., with diagnostic errors comprising the majority of errors. Delay in diagnosing breast cancer is a unique multidisciplinary phenomenon involving primary care physicians, gynecologists, radiologists, pathologists, and general surgeons. The New York medical malpractice court system remains among the most active court systems in the country. The purpose of this study is to analyze the characteristics of medical malpractice litigation involving br...

AbbVie and J&J dominate clinical trial development in psoriatic arthritis, says GlobalData.

What Have We Learned From Malpractice Claims Involving the Surgical Management of Benign Biliary Disease?: A 128 Million Dollar Question.

We aimed to study the contributing factors and costs of malpractice claims involving the surgical management of benign biliary disease given the emotional, physical, and financial toll of these claims on patients, providers, and the healthcare system.

Classifying Stage IV Lung Cancer From Health Care Claims: A Comparison of Multiple Analytic Approaches.

Cancer stage is a key determinant of outcomes; however, stage is not available in claims-based data sources used for real-world evaluations. We compare multiple methods for classifying lung cancer stage from claims data.

Identifying Patients with Pulmonary Arterial Hypertension (PAH) Using Administrative Claims Algorithms.

Retrospective administrative claims database studies provide real-world evidence about treatment patterns, healthcare resource utilization, and costs for patients and are increasingly used to inform policy making, drug formulary, and regulatory decisions. However, there is no standard methodology to identify patients with pulmonary arterial hypertension (PAH) from administrative claims data. Given the number of approved drugs now available for patients with PAH, the cost of PAH treatments, and the significa...

A chicken bioreactor for efficient production of functional cytokines.

The global market for protein drugs has the highest compound annual growth rate of any pharmaceutical class but their availability, especially outside of the US market, is compromised by the high cost of manufacture and validation compared to traditional chemical drugs. Improvements in transgenic technologies allow valuable proteins to be produced by genetically-modified animals; several therapeutic proteins from such animal bioreactors are already on the market after successful clinical trials and regulato...

Associations between lifetime traumatic experiences and HIV-risk behaviours amongst young men living in informal settlements in South Africa: A cross-sectional analysis and structural equation model.

Qualitative research emphasizes men's experiences of trauma increase HIV-risk. We seek to understand associations between experience of traumatic events and HIV-risk behaviours amongst heterosexual men in two trials in urban informal settlements in South Africa.

Market and Patent Analyses of Wearables in Medicine.

Wearable medical devices (WMDs) will advance point-of-care diagnostics and therapeutics. This article analyses the market and patents for wearable devices. Activity monitors have the largest market share, and the intellectual property landscape is dominated by electronics corporations. However, the majority of these patents have not been realized in commercial products.

Evaluation of Socioeconomic Status Indicators for Confounding Adjustment in Observational Studies of Medication Use.

Methodologic research evaluating confounding due to socioeconomic status (SES) in observational studies of medications is limited. We identified 7,109 patients who initiated brand or generic atorvastatin from Medicare claims (2011-2013) linked to electronic medical records and census data. We created a propensity score (PS) containing only claims-based covariates and augmented it with additional claims-based proxies for SES, ZIP code, and block group level SES. Cox models with PS fine-stratification and wei...

No conscientious objection without normative justification: a reply.

Benjamin Zolf, in his recent paper 'No conscientious objection without normative justification: Against conscientious objection in medicine', attempts to establish that in order to rule out arbitrary conscientious objections, a reasonability constraint is necessary. This, he contends, requires normative justification, and the subjective beliefs that ground conscientious objections cannot easily be judged by normative criteria. Zolf shows that the alternative of using extrinsic criteria, such as requiring th...

Yellow fever vaccination for immunocompromised travellers: unjustified vaccination hesitancy?

Administrative claims data to support pragmatic clinical trial outcome ascertainment on cardiovascular health.

Health plan administrative claims data present a cost-effective complement to traditional trial-specific ascertainment of clinical events typically conducted through patient report or a single health system electronic health record. We aim to demonstrate the value of health plan claims data in improving the capture of endpoints in longitudinal pragmatic clinical trials.

Health care claims per medical specialty in the Netherlands: a 10-year overview.

To analyse the quantity and size of health care claims per medical specialty in the past 10 years.

Socioeconomic status, health related behaviour, and self-rated health of children living in Roma settlements in Hungary.

The poor health of Roma is well documented, but there is only limited data regarding the health of Roma children. The aim of this study was to describe the socioeconomic status, health related behaviour, and health of children living in segregated Roma settlements, and to compare the data with that of non-Roma children.

Class and objectification: An investigation into the relationship between women's social class and self- and other-objectification.

This paper aims to investigate the relationship between women's social class and their levels of self- and other-objectification. Two online studies comprising of multiple questionnaires were conducted: Study 1 examined the association between the social class (both objective and subjective) of 198 non-student British women and their self-objectification levels, while Study 2 turned towards the relationship between social class and other-objectification among 82 non-student British women. Our results indica...

The β-lactams retain a central place in the antibacterial armamentarium. In Gram-negative bacteria β-lactamase enzymes that hydrolyse the amide bond of the four-membered β-lactam ring are the primary resistance mechanism, with multiple enzymes disseminating on mobile genetic elements across opportunistic pathogens such as Enterobacteriaceae (e.g. Escherichia coli) and non-fermenting organisms (e.g. Pseudomonas aeruginosa). β-lactamases divide into four classes; the active-site serine β-lactamases (SBLs...


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