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PubMed Journals Articles About "Acasti Pharma Grants Incentive Stock Options" RSS

13:55 EDT 25th June 2018 | BioPortfolio

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Showing "Acasti Pharma Grants Incentive Stock Options" PubMed Articles 1–25 of 1,800+

Resource Allocation Strategies to Increase the Efficiency and Sustainability of Gavi's Health System Strengthening Grants.

Despite the increase in Health System Strengthening (HSS) grants, there is no consensus among global health actors about how to maximize the efficiency and sustainability of HSS programs and their resulting gains. To formally analyze and compare the efficiency and sustainability of Gavi's HSS grants, we investigated the factors, events, and root causes that increased the time and effort needed to implement HSS grants, decreased expected outcomes, and threatened the continuity of activities and the sustainab...


Development of stock correlation networks using mutual information and financial big data.

Stock correlation networks use stock price data to explore the relationship between different stocks listed in the stock market. Currently this relationship is dominantly measured by the Pearson correlation coefficient. However, financial data suggest that nonlinear relationships may exist in the stock prices of different shares. To address this issue, this work uses mutual information to characterize the nonlinear relationship between stocks. Using 280 stocks traded at the Shanghai Stocks Exchange in China...

Steps to Stock: Keeping Students Safe With Fully Implemented Stock Epinephrine.

Laws have been passed across the United States to either allow or mandate the use of stock epinephrine in the school setting. The challenge remains for our schools to fully implement the use of this life-saving medication. Barriers to implementation exist, but quality tools are available to support the school nurse.


Cardiothoracic surgery training grants provide protected research time vital to the development of academic surgeons.

The Ruth L. Kirschstein Institutional National Research Service Award (T32) provides institutions with financial support to prepare trainees for careers in academic medicine. In 1990, the Cardiac Surgery Branch of the National Heart, Lung and Blood Institute (NHLBI) was replaced by T32 training grants, which became crucial sources of funding for cardiothoracic (CT) surgical research. We hypothesized that T32 grants would be valuable for CT surgery training and yield significant publications and subsequent f...

The current state of funded NIH grants in implementation science in genomic medicine: a portfolio analysis.

PurposeImplementation science offers methods to evaluate the translation of genomic medicine research into practice. The extent to which the National Institutes of Health (NIH) human genomics grant portfolio includes implementation science is unknown. This brief report's objective is to describe recently funded implementation science studies in genomic medicine in the NIH grant portfolio, and identify remaining gaps.MethodsWe identified investigator-initiated NIH research grants on implementation science in...

Carbon stock of Moso bamboo (Phyllostachys pubescens) forests along a latitude gradient in the subtropical region of China.

Latitude is an important factor that influences the carbon stock of Moso bamboo (Phyllostachys pubescens) forests. Accurate estimation of the carbon stock of Moso bamboo forest can contribute to sufficient evaluation of forests in carbon sequestration worldwide. Nevertheless, the effect of latitude on the carbon stock of Moso bamboo remains unclear. In this study, a field survey with 36 plots of Moso bamboo forests along a latitude gradient was conducted to investigate carbon stock. Results showed that the ...

A guide to manufacturing CAR T cell therapies.

In recent years, chimeric antigen receptor (CAR) modified T cells have been used as a treatment for haematological malignancies in several phase I and II trials and with Kymriah of Novartis and Yescarta of KITE Pharma, the first CAR T cell therapy products have been approved. Promising clinical outcomes have yet been tempered by the fact that many therapies may be prohibitively expensive to manufacture. The process is not yet defined, far from being standardised and often requires extensive manual handling ...

Testing the role of external debt in environmental degradation: empirical evidence from Turkey.

This study investigates the role of external debt stock in Turkey, which has suffered from heavy (external and domestic) debt stock for many years. Annual data from 1960 to 2013 was analyzed using time series analysis in order to study this. The results confirm the validity of the conventional environmental Kuznets curve (EKC) in the case of Turkey. However, this study also found that Turkey's external debt stock did not influence the Turkish economy's long-term EKC behavior. Fortunately, the results sugges...

A heterogeneous artificial stock market model can benefit people against another financial crisis.

This paper presents results of an artificial stock market and tries to make it more consistent with the statistical features of real stock data. Based on the SFI-ASM, a novel model is proposed to make agents more close to the real world. Agents are divided into four kinds in terms of different learning speeds, strategy-sizes, utility functions, and level of intelligence; and a crucial parameter has been found to ensure system stability. So, some parameters are appended to make the model which contains zero-...

Analysis of the distribution and scholarly output from National Institute of Academic Anaesthesia (NIAA) research grants.

The National Institute of Academic Anaesthesia (NIAA) was founded in 2008 to lead a UK strategy for developing academic anaesthesia. We aimed to assess the distribution of applications and quantify the academic returns of NIAA-supported research grants, as this has hitherto not been analysed. We sought data on the baseline characteristics of all grant applicants and recipients. Every grant recipient from 2008 to 2015 was contacted to ascertain the status of their supported research projects. We also examine...

Moving pharma contracting into the era of accountability.

A dynamic analysis of S&P 500, FTSE 100 and EURO STOXX 50 indices under different exchange rates.

In this study, we assess the dynamic evolution of short-term correlation, long-term cointegration and Error Correction Model (hereafter referred to as ECM)-based long-term Granger causality between each pair of US, UK, and Eurozone stock markets from 1980 to 2015 using the rolling-window technique. A comparative analysis of pairwise dynamic integration and causality of stock markets, measured in common and domestic currency terms, is conducted to evaluate comprehensively how exchange rate fluctuations affec...

Use of antibiotics in bones : Prophylaxis and current treatment standards.

Treatment of bone infection is difficult due the systemic administration of antibiotics, which means that only low concentrations reach the inflamed bone tissue. Loss of bone stock is common in osteomyelitis and device associated infection. Local antibiotics are administered in several ways for prophylactic purposes and also for treatment of bone infection. We intend to show the options and limitations of clinical use of antibiotic-loaded bone grafts.

Extension of biomass estimates to pre-assessment periods using density dependent surplus production approach.

Biomass reconstructions to pre-assessment periods for commercially important and exploitable fish species are important tools for understanding long-term processes and fluctuation on stock and ecosystem level. For some stocks only fisheries statistics and fishery dependent data are available, for periods before surveys were conducted. The methods for the backward extension of the analytical assessment of biomass for years for which only total catch volumes are available were developed and tested in this pap...

A "not-for-profit" regulatory model for legal recreational cannabis: Insights from the regulation of gaming machine gambling in New Zealand.

A dozen or more regulatory frameworks have been proposed for legal cannabis but many of the "not-for-profit" options have yet to be developed in any detail, reducing the likelihood they will be seriously considered by policy makers. New Zealand's innovative "not-for-profit" regulatory regime for gaming machine gambling (i.e. "slot machines") has reversed the previous increase in gambling expenditure, empowered local councils to cap the number of gambling venues, and is unique in requiring the societies oper...

Hungary rewards highly cited scientists with bonus grants.

Social protection and public policy for vulnerable populations: an assessment of the Continuous Cash Benefit Program of Welfare in Brazil.

This paper describes the historical development and profile of Continuous Cash Benefit (BPC) applicants, intended for poor elderly and people with disabilities, which, since 2009, uses eligibility criteria based on the International Classification of Functioning, Disability and Health (ICF) of the WHO and is aligned with the UN Convention on the Rights of Persons with Disabilities. The behavior of benefits was determined from the analysis the coefficients of the general and non-judicial grants between 1998 ...

A mixed methods assessment of the barriers and readiness for meeting the SNAP depth of stock requirements in Baltimore's small food stores.

We sought to understand Baltimore corner store owners' awareness of and readiness for the then-approved Supplemental Nutrition Assistance Program depth of stock requirements and assess potential barriers and solutions. In-depth interviews and stocking observations were conducted in 17 corner stores in low-income food deserts of Baltimore City. Corner store owners conveyed little to no awareness of the pending depth of stock changes. Only two stores were currently ready for the requirements. Low customer dem...

Re-exploration of Microvascular Decompression in recurrent trigeminal neuralgia and intra-operative management options.

Trigeminal Neuralgia (TGN) is a debilitating disorder, and in cases where medical management is not sufficient, there are several therapeutic options available. Microvascular decompression (MVD) for TGN has been shown to be highly effective, however, the pain does recur after MVD in a small group of patients. Therapeutic options for recurrent TGN are the same as that for primary TGN including re-exploration of MVD (re-MVD). In this study we review our practice of re-MVD, comparing it to alternative options ...

Funders' Grants On Obesity Prevention And Healthy Eating.

The status of women cognitive scientists in Canada: Insights from publicly available NSERC funding data.

A crucial question within science and academia, and cognitive science specifically, is whether there is gender disparity in opportunity and advancement over the professional life span (e.g., Ceci, Ginther, Kahn, & Williams, 2014; Geraci, Balsis, & Busch, 2015; Valian, 1998). To investigate this question, we analyzed gender distributions in publicly available federal funding data from the Natural Sciences and Engineering Research Council (NSERC) of Canada that are specific to cognitive psychology and cogniti...

Profile of demand and Continuous Cash Benefits (BCP) granted to children diagnosed with microcephaly in Brazil.

The Brazilian Federal Constitution of 1988 introduced the Continuous Cash Benefits (BCP), allowing the inclusion of people with disabilities. This is a descriptive study with aggregate municipal data about the time and geographic distribution of the incidence of microcephaly related to the Zika virus in Brazil and data of the BCP grants to children diagnosed with microcephaly. Data on the demand and BCP grants to children with microcephaly since 2009 are shown. Cases of microcephaly and/or central nervous s...

Voluntary vaccinations and vaccine shortages: a theoretical analysis.

A simple dynamic model of vaccination is presented and analyzed to study how the amount of vaccines available affects people's vaccination decisions. In addition, the model is used to examine how the level of vaccination in equilibrium compares to the efficient or socially optimal level. It is shown that, when the stock of vaccines is large so that a shortage could never arise, an equilibrium is generically unique, and there is too little vaccination compared to the social optimum. When the stock of vaccine...

Carbon stocks of three secondary coniferous forests along an altitudinal gradient on Loess Plateau in inland China.

Natural forests in inland China are generally distributed in montane area and secondary due to a semi-arid climate and past anthropogenic disturbances. However, quantification of carbon (C) stock in these forests and the role of altitude in determining C storage and its partition among ecosystem components are unclear. We sampled 54 stands of three secondary coniferous forests (Larix principis-rupprechtii (LP) forest, Picea meyerii (PM) forest and Pinus tabulaeformis (PT) forest) on Loess Plateau in an alti...

Drivers and rates of stock assessments in the United States.

Fisheries management is most effective when based on scientific estimates of sustainable fishing rates. While some simple approaches allow estimation of harvest limits, more data-intensive stock assessments are generally required to evaluate the stock's biomass and fishing rates relative to sustainable levels. Here we evaluate how stock characteristics relate to the rate of new assessments in the United States. Using a statistical model based on time-to-event analysis and 569 coastal marine fish and inverte...


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