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01:50 EST 13th December 2018 | BioPortfolio

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Showing "ActX" PubMed Articles, all 1

Synergistic transcriptional changes in AMPA and GABA receptor genes support compensatory plasticity following unilateral hearing loss.

Debilitating perceptual disorders including tinnitus, hyperacusis, phantom limb pain and visual release hallucinations may reflect aberrant patterns of neural activity in central sensory pathways following a loss of peripheral sensory input. Here, we explore short- and long-term changes in gene expression that may contribute to hyperexcitability following a sudden, profound loss of auditory input to one ear. We used fluorescence in situ hybridization to quantify mRNA levels for genes encoding AMPA and GABA ...

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