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PubMed Journals Articles About "Adalimumab Biosimilar Idacio Launched Germany∨derfield=score∨derval=desc∨derfield=score∨derval=DESC" RSS

05:58 EDT 24th August 2019 | BioPortfolio

Adalimumab Biosimilar Idacio Launched Germany∨derfield=score∨derval=desc∨derfield=score∨derval=DESC PubMed articles on BioPortfolio. Our PubMed references draw on over 21 million records from the medical literature. Here you can see the latest Adalimumab Biosimilar Idacio Launched Germany∨derfield=score∨derval=desc∨derfield=score∨derval=DESC articles that have been published worldwide.

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Showing "Adalimumab Biosimilar Idacio Launched Germany derfield score derval" PubMed Articles 1–25 of 4,400+

Physical activity during pregnancy and intelligence in sons; a cohort study.

The purpose was to examine the association between exercise during pregnancy and intelligence score in offspring. We analysed data from 4008 women from the Aarhus Birth Cohort, Aarhus University Hospital, Denmark, recruited during pregnancy from July 1989 to November 1991 and their sons who were registered at conscription at 17-20 years of age. The women gave information by self-administered questionnaires during the first trimester including leisure time physical activity and weekly hours of sport. This in...


Radiotherapy for metastatic spinal cord compression; can the Rades score predict survival?

Metastatic spinal cord compression (MSCC) can be debilitating and painful and carries a poor prognosis. There is increasing evidence that MSCC can be treated with single-fraction radiotherapy. The Rades score is designed to assist in identifying better prognosis patients who may benefit from longer radiotherapy courses. This study aims to study patterns of care for MSCC at a single center in New Zealand, and assess the Rades score and other variables as predictors of survival.

A conceptual framework for an oral cancer awareness campaign in Northern Germany - Challenges in campaign development and assessment.

Initial impetus for action: Oral cancer is still an underestimated disease in terms of incidence as well as mortality rates; it requires urgent prevention and early detection. At present, there is no best-practice systematic approach to raising awareness and informing the public about about this type of cancer in Germany. This article describes a framework that covers the significant stages of conceptual development and campaign design to promote oral cancer awareness in Germany. Solution: The challenges of...


Sublingual immunotherapy of atopic dermatitis in mite-sensitized patients: a multi-centre, randomized, double-blind, placebo-controlled study.

Allergen-specific immunotherapy is widely used for allergic rhinitis and asthma treatment worldwide. This study explored the efficacy and safety of sublingual immunotherapy (SLIT) with the extracts of ( Drops) on house dust mites (HDM)-induced atopic dermatitis (AD). 239 patients with HDM-induced AD were recruited and exposure to a multi-centre, randomized, double-blind, and placebo-controlled clinical trials for 36 weeks, which were randomly divided into placebo and sublingual Drops groups (high-dose, ...

Using sepsis scores in emergency department and ward patients.

Sepsis-3, published in 2016, defined sepsis as 'life-threatening organ dysfunction caused by a dysregulated host response to infection'. Instead of systemic inflammatory response syndrome (SIRS), calculating the Sequential Organ Failure Assessment (SOFA) score was recommended. The complexity of SOFA also led to the introduction of quick SOFA (qSOFA) as a bedside tool. The simultaneous removal of SIRS and introduction of qSOFA belies their significant differences, with SIRS having a high sensitivity but very...

Continuity of care for newly diagnosed diabetic patients: A population-based study.

This study explores whether continuity of care is associated with health care outcomes and medical care use among patients with newly diagnosed diabetes. A retrospective cohort analysis was performed using the Taiwanese National Health Insurance database, and cases were followed up from January 2010 to December 2012. Four thousand and seven patients with newly diagnosed diabetes were followed for 3 years. The continuity of care was measured using the continuity of care index (COCI) and the usual provider co...

Methodology for building a geographical accessibility health index throughout metropolitan France.

Spatial accessibility to health services is a key factor in terms of public health. Even though some tools are available, establishing accessibility criteria applicable from one geographic scale to another remains difficult. Therefore, we propose a method for creating a health accessibility index applicable on a large geographic scale, based on a methodology that overcomes the limitations of political-administrative divisions and which allows a multi-scalar approach to be implemented. The index highlights, ...

Higher self-reported severity of atopic dermatitis in adults is associated with poorer self-reported health-related quality of life in France, Germany, the UK and the US.

Better understanding of the relationship between atopic dermatitis (AD) severity and health-related quality of life (HRQoL) could help improve knowledge about the benefits of a more effective treatment of people with AD.

Chromium Oxide Tetrafluoride and Its Reactions with Xenon Hexafluoride; the XeF5+ and Xe2F11+ Salts of the CrVIOF5-, CrVOF52-, CrV2O2F82-, and CrIVF62- Anions.

Molten mixtures of XeF6 and CrVIOF4 are shown to react by means of F2 elimination to form [XeF5][Xe2F11][CrVOF5]∙2CrVIOF4, [XeF5]2[CrIVF6]∙2CrVIOF4, [Xe2F11]2[CrIVF6], and [XeF5]2[CrV2O2F8], whereas their reactions in anhydrous hydrogen fluoride (aHF) and CFCl3/aHF yield [XeF5]2[CrV2O2F8]∙2HF and [XeF5]2[CrV2O2F8] ∙2XeOF4. These salts are the only high-oxidation state Group 6 oxyfluoro-anions known to stabilize noble-gas cations. Their reaction pathways involve redox transformations that give [XeF5]...

A Nickel Complex Containing a Pyramidalized, Ambiphilic Pincer Germylene Ligand.

Reaction of N-heterocyclic carbene (NHC)-stabilized PGeP-type germylene Ge{o-(PiPr2)C6H4}2·MeIiPr (1) (MeIiPr = 1,3-diisopropyl-4,5-dimethylimidazol-2-ylidene) with Ni(cod)2 gave pincer germylene complex Ni[Ge{o-(PiPr2)C6H4}2](MeIiPr) (2), in which the Ge center of 2 is significantly pyramidalized. Theoretical calculation on 2 predicted the ambiphilicity of the germanium center, which was confirmed by reactivity studies. Thus, complex 2 reacted with both Lewis base MeIMe (MeIMe = 1,3,4,5-tetramethylimidazo...

In-Situ Transformation of Prussian-Blue Analogue-Derived Bimetallic Carbide Nanocubes in Water Oxidation: Applications for Energy Storage and Conversion.

Using bimetallic Prussian-blue analogue (PBA) as precursor is effective for preparing electrocatalysts for oxygen evolution reaction (OER), however, the role of these PBA-derived catalysts in OER is still ambiguous. Herein, by simply controlling synthesis temperature, a bimetallic PBA-derived O,N-codoped Ni-Fe carbide, can be well tuned to optimize structure and OER performance. Importantly, by a series of ex-situ and in-situ investigations, real active species of NiFeOxHy are in-situ formed on the surface ...

Dynamic Behaviours in Microcompartments.

Compartmentalization is recognized to be a primary step for the assembly of non-living matter towards the construction of life-like micro-ensembles. To date, a host of hollow microcompartments with various functionalities have been widely developed. Within this respect, given that dynamic behaviour is one of the fundamental features to distinguish living ensembles from non-livings, the design and construction of the microcompartments with various dynamic behaviours are attracting considerable interest in a ...

Retraction: Unstable Supramolecular Structure of BmimBF in Aqueous Solution.

Immunohistochemical analysis of Bcl-2, nuclear S100A4, MITF and Ki67 for risk stratification of early-stage melanoma - A combined IHC score for melanoma risk stratification.

Overall survival (OS) in patients with early-stage malignant melanoma differs. To date, there are no established prognostic markers. We aimed to contribute to a better understanding of potential prognostic immunohistochemical markers for risk stratification.

The : A Reflective Discussion.

Research about lactation and breastfeeding has exploded since the () began publishing in 1985. To discuss the 3-decade-long role of the in promoting, supporting, and disseminating lactation research, editors convened a multidisciplinary group of lactation researchers and providers which comprised three senior researchers and one clinical practitioner, all of whom have a long history of lactation advocacy. Their discussion took place on July 1, 2019. Dr Aimee Eden is a medical anthropologist who leads the ...

Semi-quantitative Assessment of Cytomorphologic Features Can Predict Mutation Status of Thyroid Nodules with Indeterminate Cytologic Diagnosis.

Molecular diagnostics increasingly direct the management of thyroid nodules with an indeterminate cytologic diagnosis. This study was undertaken to correlate cytomorphologic features with the molecular profiles in an effort to identify features predictive of molecular aberrations. 189 thyroid nodules with an indeterminate thyroid cytology diagnosis (atypia of undetermined significance, suspicious for follicular lesion, and suspicious for malignancy) with an adequate sample submitted for targeted mutation de...

Circulating microRNAs as predictive biomarkers of myocardial infarction: Evidence from the HUNT study.

Several risk prediction models for coronary heart disease (CHD) are available today, however, they only explain a modest proportion of the incidence. Circulating microRNAs (miRs) have recently been associated with processes in CHD development, and may therefore represent new potential risk markers. The aim of the study was to assess the incremental value of adding circulating miRs to the Framingham Risk Score (FRS).

Passive sampling of organic contaminants across the water-sediment interface of an urban stream.

Passive sampling is a well-established tool for monitoring time-weighted average concentrations of polar and semi-polar organic contaminants in streams at flow velocities between 0.1 and 0.4 m s. However, its application under low-flow conditions (10 to 0.01 m s) - as encountered in hyporheic zones - has been scarcely reported. In this study, 3 novel passive sampler configurations were developed for the monitoring of (semi-)polar organic pollutants and related transformation products across the wate...

Monitoring annoyance and stress effects of wind turbines on nearby residents: A comparison of U.S. and European samples.

As wind turbines and the number of wind projects scale throughout the world, a growing number of individuals might be affected by these structures. For some people, wind turbine sounds and their effects on the landscape can be annoying and could even prompt stress reactions. This comparative study analyzed a combined sample of survey respondents from the U.S., Germany and Switzerland. It utilized a newly developed assessment scale (AS-Scale) to reliably characterize these stress-impacted individuals living ...

Nicotine effects on cognitive remediation training outcome in people with schizophrenia: A pilot study.

Cognitive remediation training can alleviate cognitive impairment associated with schizophrenia, but the impact is limited by small effect sizes. The present study aimed at augmenting training effects by administering nicotine prior to training sessions. Twenty-five people with schizophrenia were enrolled in a 10-week, 5 days/week, computerized cognitive training regimen. Participants were randomized to two treatment groups: nicotine or placebo. Every Monday and Thursday, the nicotine group received a nicot...

Tuberculosis vaccination sequence effect on protection in wild boar.

The Eurasian wild boar (Sus scrofa) is a reservoir for tuberculosis (TB) in which vaccination is a valuable tool for control. We evaluated the protection and immune response achieved by homologous and heterologous regimes administering BCG and heat-inactivated Mycobacterium bovis (IV). Twenty-one wild boar piglets were randomly allocated in five groups: Control, homologous BCG, homologous IV, heterologous IV-BCG, heterologous BCG-IV. Significant 67% and 66% total lesion score reductions were detected in hom...

Response to Letter to the editor: Interrater Reliability of Ultrasound in the Diagnosis of Sialolithiasis: Methodological Issues. Interrater Reliability of Ultrasound: Methodological Issues.

Interrater Reliability of Ultrasound in the Diagnosis of Sialolithiasis: Methodological Issues.

Treatment of Closed Tibia Shaft Fractures in Children: A Systematic Review and Meta-Analysis.

Tibia fractures are among the most common long-bone fractures in children. Despite this, there is no current consensus on the optimal treatment strategy for closed displaced tibia shaft fractures in the pediatric patient population. The aim of this study is to compare the reported complications and outcomes of reduction and cast immobilization versus flexible intramedullary nailing in the treatment of pediatric tibia shaft fractures. We followed the Preferred Reporting Items for Systematic Reviews and Meta-...

Prediction and validation of potent peptides against Herpes Simplex Virus Type 1 (HSV-1) via immunoinformatic and systems biology approach.

The human herpes simplex virus type 1 (HSV-1) is an extremely rampant human pathogen and its infection could cause life-long diseases, including the central nervous system (CNS) disorders. The glycoproteins of HSV-1 such as glycoprotein B, glycoprotein C, glycoprotein D, glycoprotein H & glycoprotein L are highly involved in mediating the viral attachment and infection of the host cell. Therefore, immunoinformatic approaches followed by molecular dynamics simulation and systems biology has been used to anal...


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