PubMed Journals Articles About "Agios Reports Second Quarter 2017 Financial Results" RSS

13:45 EST 24th November 2017 | BioPortfolio

Agios Reports Second Quarter 2017 Financial Results PubMed articles on BioPortfolio. Our PubMed references draw on over 21 million records from the medical literature. Here you can see the latest Agios Reports Second Quarter 2017 Financial Results articles that have been published worldwide.

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Showing "Agios Reports Second Quarter 2017 Financial Results" PubMed Articles 1–25 of 47,000+

Reports of unintended consequences of financial incentives to improve management of hypertension.

Given the increase in financial-incentive programs nationwide, many physicians and physician groups are concerned about potential unintended consequences of providing financial incentives to improve quality of care. However, few studies examine whether actual unintended consequences result from providing financial incentives to physicians. We sought to document the extent to which the unintended consequences discussed in the literature were observable in a randomized clinical trial (RCT) of financial incent...

Conceptual and Empirical Approaches to Financial Decision-making by Older Adults: Results from a Financial Decision-making Rating Scale.

The objectives of this study were threefold: (1) to empirically test the conceptual model proposed by the Lichtenberg Financial Decision-making Rating Scale (LFDRS); (2) to examine the psychometric properties of the LFDRS contextual factors in financial decision-making by investigating both the reliability and convergent validity of the subscales and total scale, and (3) extending previous work on the scale through the collection of normative data on financial decision-making.

Measures of Financial Capacity: A Review.

Capacity to manage finances and make financial decisions can affect risk for financial exploitation and is often the basis for legal determinations of conservatorship/guardianship. Several structured assessments of financial capacity have been developed, but have not been compared regarding their focus, validity, or reliability. Therefore, we conducted a review of financial capacity measures to examine these factors.

Setting the stage for universal financial distress screening in routine cancer care.

Financial burden from cancer treatment is increasingly being recognized as a threat to optimal access, quality, and outcomes of cancer care for patients. Although research in the area is moving at a fast pace, multiple questions remain unanswered, such as how to practically integrate the assessment and management of financial burden into routine health care delivery for patients with cancer. Although psychological distress screening for patients undergoing cancer treatment now is commonplace, the authors ra...

Testing the Financial Capability Framework: Findings from YouthSave-Impact Study Kenya.

In sub-Saharan Africa (SSA), youths (23 years or younger)-who account for almost half the population-are particularly vulnerable to poverty and exclusion from financial markets and intermediaries. In addition, a significant factor in the financial instability of the region appears to be the economic functioning of its youths. In recent years, social work interventions throughout the region have focused on investing in the economic functioning of youths. This study looked at baseline data from one such inter...

Numerical Activities of Daily Living - Financial (NADL-F): A tool for the assessment of financial capacities.

Financial capacity is the ability to manage one's own finances according to self-interests. Failure in financial decisions and lack of independence when dealing with money can affect people's quality of life and are associated with neuropsychological deficits or clinical conditions such as mild cognitive impairment or Alzheimer's disease. Despite the importance of evaluating financial capacity in the assessment of patients with neuropsychological and psychiatric disorders, only a few tools have been develop...

The association between hip dysfunction and lower quarter injuries in long distance runners: a systematic review protocol.

The objective of this review is to establish the association between hip dysfunction and lower quarter (low back and lower limb) injuries in long distance runners. Specifically the review question is: Are long distance runners with hip dysfunction at risk of lower quarter (low back and lower limb) injuries?

Feeling Stressed under the Sun? RPA1 Acetylation to the Rescue.

Nucleotide excision repair (NER) requires replication protein A (RPA), among others, to respond to DNA damaging agents. In this issue of Cell Reports, He et al. (2017) and Zhao et al. (2017) show acetylation of RPA1 regulates the UV-induced DNA damage response.

Prevalence of Financial Fraud and Scams Among Older Adults in the United States: A Systematic Review and Meta-Analysis.

The financial exploitation of older adults was recently recognized by the Centers for Disease Control and Prevention as a serious public health problem. Knowledge of the prevalence of elder financial exploitation is mostly limited to the category of financial abuse, which occurs in relationships involving an expectation of trust. Little is known about the other major category of elder financial exploitation-elder financial fraud and scams, which is perpetrated by strangers. A valid estimate of elder financi...

Combined Effects of Glucocorticoid and Noradrenergic Activity on Loss Aversion.

Loss aversion is a well-known behavioral regularity in financial decision-making, describing humans' tendency to overweigh losses compared to gains of the same amount. Recent research indicates that stress and associated hormonal changes affect loss aversion, yet the underlying neuroendocrine mechanisms are still poorly understood. Here, we investigated the causal influence of two major stress neuromodulators, cortisol and noradrenaline, on loss aversion during financial decision-making. In a double-blind, ...

Authors of Clinical Trials Reported Individual and Financial Conflicts of Interest More Frequently than Institutional and non-financial Ones: a Methodological Survey.

Conflicts of interest (COI) are increasingly recognised as important to disclose and manage in health research. The objective of this study was to assess the reporting of both financial and non-financial COI by authors of randomised controlled trials published in a representative sample of clinical journals.

Financial Capacity and its Cognitive Predictors in Progressive Multiple Sclerosis.

Financial capacity is a cognitively-complex activity of daily living that has been shown to decline in a number of neurocognitive disorders. Although it has been well established that cognitive decline is common in multiple sclerosis (MS), little is known about possible financial capacity impairment in people with MS. Thus, the objective of the current study is to investigate financial capacity and its neurocognitive correlates in MS.

Support Buffers Financial Strain's Effect on Health-related Quality of Life.

Financial strain represents a perceived inability to meet financial needs and obligations and is associated with poorer health outcomes. Distinct facets of perceived social support may mitigate the deleterious effects of financial strain on health. In the present study, we examined the extent to which appraisal, belonging, and tangible social support ameliorate the effects of financial strain on health-related quality of life (HRQoL).

Controlling the Bidirectional Circular Polarization States Using Ultrathin Back-to-Back Quarter-Wave Plates Cavity.

Efficiently manipulating the polarization states of electromagnetic waves is of great importance for communication, imaging, and sensing. In this paper, we aim to control the circular polarization states, e.g., left-hand, or right-hand, for the bidirectional radiated waves utilizing a pair of back-to-back quarter-wave plates, which are integrated within an ultrathin cavity. As an example, a bidirectional circularly polarized wave with the same helicity in forward and backward is generated based on numerical...

Evaluation of an automated milk leukocyte differential test and the California mastitis test for detecting intramammary infection in early- and late-lactation quarters and cows.

Study objectives were to (1) describe the diagnostic test characteristics of an automated milk leukocyte differential (MLD) test and the California mastitis test (CMT) to identify intramammary infection (IMI) in early- (EL) and late-lactation (LL) quarters and cows when using 3 different approaches to define IMI from milk culture, and (2) describe the repeatability of MLD test results at both the quarter and cow level. Eighty-six EL and 90 LL Holstein cows were sampled from 3 Midwest herds. Quarter milk sam...

A Triad of Crystals Sheds Light on MDGA Interference with Neuroligation.

Neurexins and neuroligins form trans-synaptic complexes that promote synapse development. In this issue of Neuron, Aricescu and colleagues (Elegheert et al., 2017) complement and strengthen two recent reports by the Kim and Rudenko teams (Kim et al., 2017; Gangwar et al., 2017) to dissect the molecular determinants by which MDGAs challenge the neurexin-neuroligin partnership.

Does competition improve financial stability of the banking sector in ASEAN countries? An empirical analysis.

This study examines the influence of competition on the financial stability of the commercial banks of Association of Southeast Asian Nation (ASEAN) over the 1990 to 2014 period. Panzar-Rosse H-statistic, Lerner index and Herfindahl-Hirschman Index (HHI) are used as measures of competition, while Z-score, non-performing loan (NPL) ratio and equity ratio are used as measures of financial stability. Two-step system Generalized Method of Moments (GMM) estimates demonstrate that competition measured by H-statis...

Understanding Financial Statements in Clinical Practice: A Primer.

The purpose of this article is to describe the different types of financial statements and the information they contain regarding the current and long-term financial health of a business practice. These statements are essential to guiding strategic decision making for physicians and executives.

ERAS-Value based surgery.

This paper reviews implementation of ERAS and its financial implications. Literature on clinical outcomes and financial implications were reviewed. Reports from many different surgery types shows that implementation of ERAS reduces complications and shortens hospital stay. These improvements have major impacts on reducing the cost of care even when costs for implementation, and investment in time for personnel and training is accounted for. The conclusion is that ERAS is an excellent example of value based ...

Doing well by doing good: Evaluating the influence of patient safety performance on hospital financial outcomes.

As financial pressures on hospitals increase because of changing reimbursement structures and heightened focus on quality and value, the association between patient safety performance and financial outcomes remains unclear.

Disclosure of Financial Conflicts of Interest in Plastic and Reconstructive Surgery.

Recent articles in the scientific literature have expressed concerns about financial conflicts of interest in the profession of medicine in general and the specialty of plastic surgery in particular. Disclosure of financial ties to industry has been regarded as an address of a possible bias. The policies of medical journals places responsibility on authors for self-reporting of financial conflicts of interest, yet underreporting of conflicts of interest has occurred. The investigative hypothesis was that au...

The Quarter Prone Position Increases Oxygen Saturation in Premature Infants Using Continuous Positive Airway Pressure.

A primary problem that occurs in premature infants is oxygenation disorders, thus requiring respiratory support, including continuous positive airway pressure (CPAP). The effectiveness of CPAP can be improved by adjusting the body's position, so the aim of this study was to examine the effect of the quarter prone position on the oxygenation status of preterm infants using CPAP. This study used a randomized controlled trial with a crossover design. A group of 15 preterm infants receiving CPAP was selected, a...

Comments on: Lyubarova, R. and Gosmanova, E.O. Mineralocorticoid Receptor Blockade in End-Stage Renal Disease. Current Hypertension Reports, 2017. 19(5).

Financial Hardship, Condomless Anal Intercourse and HIV Risk Among Men Who Have Sex with Men.

The objective of this study was to examine the association between financial hardship, condomless anal intercourse and HIV risk among a sample of men who have sex with men (MSM). Users of a popular geosocial networking application in Paris were shown an advertisement with text encouraging them to complete a anonymous web-based survey (n = 580). In adjusted multivariate models, high financial hardship (compared to low financial hardship) was associated with engagement in condomless anal intercourse (aRR 1....

Highlights from the Biennial International Congress on Schizophrenia Research (ICOSR), March 24-March 28, 2017.

The 2017 International Congress on Schizophrenia Research, held in San Diego, California (March 24-28, 2017), attracted over 900 attendees from 34 countries. With the gracious assistance of Congress president James Meador-Woodruff, we bring you the following reports on the prospects for new drugs to treat schizophrenia.

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