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PubMed Journals Articles About "Air Pollution Study: The Effect Of Ozone On The Lung" RSS

01:56 EST 19th November 2018 | BioPortfolio

Air Pollution Study: The Effect Of Ozone On The Lung PubMed articles on BioPortfolio. Our PubMed references draw on over 21 million records from the medical literature. Here you can see the latest Air Pollution Study: The Effect Of Ozone On The Lung articles that have been published worldwide.

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Showing "Pollution Study Effect Ozone Lung" PubMed Articles 1–25 of 75,000+

Significant effects of exposure to relatively low level ozone on daily mortality in 17 cities from three Eastern Asian Countries.

Studies have examined the variation in mortality risk associated with ambient ozone. We conducted an international cooperation study for investigating the non-linear ozone-mortality association accounting for lag effect and for examining the ozone level with significant health effect.


Ozone risk assessment of castor (Ricinus communis L.) cultivars using open top chamber and ethylenediurea (EDU).

Castor bean (Ricinus communis L.) an important non-edible oilseed crop, is a prominent feed stock towards the generation of renewable materials for industrial production which has multiple applications ranging from cosmetics to biofuels industry. India accounts for 76% of the total world production of castor oil seed. However, major concern for developing countries like India where expanding economy led to rapid increases in gases like NOx, CO and VOCs photochemically form ozone. Ozone is strong oxidant tha...

The burden of ozone pollution on years of life lost from chronic obstructive pulmonary disease in a city of Yangtze River Delta, China.

Ambient ozone is one of the most important air pollutants with respect to its impacts on human health and its increasing concentrations globally. However, studies which explored the burden of ozone pollution on chronic obstructive pulmonary disease (COPD) and estimated the relevant economic loss were rare.


Exploration of the heterogeneous effect of climate change on ozone concentration in an urban environment.

Ozone is a significant causative agent of mortality in cities. Urban environments are expressly vulnerable to global warming because of the extensive emission of air pollutants with urban heat island effect enhancing much rapidly the ozone concentration than in the less urbanized regions. This effect previously was not studied in local scale. It was hypothesized that climate change will cause heterogenic increase of ozone concentration in the different parts of the cities. To study this effect, the near-sur...

Impact of ozone on claudins and tight junctions in the lungs.

Claudins (CLDNs) are a major transmembrane protein component of tight junctions (TJs) in endothelia and epithelia. CLDNs are not only essential for sustaining the role of TJs in cell permeability but are also vital for cell signaling through protein-protein interactions. Ozone induces oxidative stress and lung inflammation in humans and experimental models, but the impact of ozone on claudins remains poorly understood. This study was to determine the expression of TJ proteins, such as claudin 3, 4, 5, and 1...

Molecular insights into the effect of ozone on human hemoglobin in autohemotherapy: Highlighting the importance of the presence of blood antioxidants during ozonation.

Ozone has been known for several decades, with its antiseptic and therapeutic effects determined by the hormesis theory. It is shown that the therapeutic efficacy of ozone therapy may be partly due to the controlled and moderate oxidative stress produced by the reaction of ozone with several biological components. In this study, the effect of ozone on healthy human hemoglobin (Hb) in the whole blood environment (in the presence of antioxidants) and in the purified form (in the absence of antioxidants) is in...

Seasonal association between ambient ozone and hospital admission for respiratory diseases in Hanoi, Vietnam.

Many studies have indicated the detrimental effect of ambient ozone to respiratory health in different countries. The levels of ozone in Hanoi, Vietnam are frequently above the WHO guideline but very few studies on the effects of ambient ozone on human health have been conducted in this location. This study aimed to examine the effects of ozone on hospital admission for respiratory diseases in Hanoi, by diseases, ages and seasons.

Tropospheric ozone affects SRB1 levels via oxidative post-translational modifications in lung cells.

Exposure to air pollution is associated with increased respiratory morbidities and susceptibility to lung dysfunction. Ozone (O) is commonly recognized as one of the most noxious air pollutant and has been associated with several lung pathologies. It has been demonstrated that decreased lung disorder severity and incidence are connected with the consumption of a diet rich in fruits and vegetables, suggesting that higher intake of dietary micronutrients and phytoactive compounds can be beneficial. However, d...

Cardiovascular function and ozone exposure: The Multicenter Ozone Study in oldEr Subjects (MOSES).

To date, there have been relatively few studies of acute cardiovascular responses to controlled ozone inhalation, although a number of observational studies have reported significant positive associations between both ambient ozone levels and acute cardiovascular events and long-term ozone exposure and cardiovascular mortality.

Strong ozone production at a rural site in theNorth China Plain: Mixed effects of urban plumesand biogenic emissions.

Regional ozone (O) pollution has drawn increasing attention in China over the recent decade, but the contributions from urban pollution and biogenic emissions have not been clearly elucidated. To better understand the formation of the regional O problem in the North China Plain (NCP), intensive field measurements of O and related parameters were conducted at a rural site downwind of Ji'nan, the capital city of Shandong province, in the summer of 2013. Markedly severe O pollution was recorded, with the O mix...

Pre- and postnatal exposure of mice to concentrated urban PM decreases the number of alveoli and leads to altered lung function at an early stage of life.

Gestational exposure to air pollution is associated with negative outcomes in newborns and children. In a previous study, we demonstrated a synergistic negative effect of pre- and postnatal exposure to PM on lung development in mice. However, the means by which air pollution affects development of the lung have not yet been identified. In this study, we exposed pregnant BALB/c mice and their offspring to concentrated urban PM (from São Paulo, Brazil; target dose 600 μg/m for 1 h daily). Exposure was s...

Functional and morphological differences of the lung upon acute and chronic ozone exposure in mice.

Environmental air pollutants including ozone cause severe lung injury and aggravate respiratory diseases such as asthma and COPD. Here we compared the effect of ozone on respiratory epithelium injury, inflammation, hyperreactivity and airway remodeling in mice upon acute (1ppm, 1 h) and chronic exposure (1.5ppm, 2 h, twice weekly for 6 weeks). Acute ozone exposure caused respiratory epithelial disruption with protein leak and neutrophil recruitment in the broncho-alveolar space, leading to lung inflamma...

Ozone protects the rat lung from ischemia-reperfusion injury by attenuating NLRP3-mediated inflammation, enhancing Nrf2 antioxidant activity and inhibiting apoptosis.

Ischemia-reperfusion injury (IRI) is a major cause of lung dysfunction during cardiovascular surgery, heart transplantation and cardiopulmonary bypass procedures, and the inflammatory response, oxidative stress, and apoptosis play key and allegedly maladaptive roles in its pathogenesis. The aim of this study was to initially elucidate whether ozone induces oxidative preconditioning by activating nuclear factor (erythroid-derived 2)-like 2 (Nrf2) and secondly to determine whether ozone oxidative precondition...

A national case-crossover study on ambient ozone pollution and first-ever stroke among Chinese adults: Interpreting a weak association via differential susceptibility.

Evidence suggesting an association between ozone exposure and stroke risk remains inconsistent; variations in the distributions of susceptibilities of the study populations may explain some of it. We examined the hypothesis in a general Chinese population. During 2013-2015, 1356 first-ever stroke events were selected from a large representative sample, the China National Stroke Screening Survey (CNSSS) database; daily maximal 8-hour ozone concentrations were obtained from spatiotemporally interpolated estim...

Understanding long-term variations of meteorological influences on ground ozone concentrations in Beijing During 2006-2016.

Recently, ground ozone has become one major airborne pollutant and the frequency of ozone-induced pollution episodes has increased rapidly across China. However, due to the lack of long-term observation data, relevant research on the characteristics and influencing factors of urban ozone concentrations remains limited. Based on ground ozone observation data during 2006-2016, we quantified the causality influence of individual meteorological factors on ozone concentrations in Beijing using a convergent cross...

Observational Study of Air Pollution Complex in Nanjing in June 2014.

Studying the evolution of secondary inorganic aerosols, which are important components of PM, is crucial to improving our understanding about the air pollution in big cities. This study investigates the evolution and factors of secondary inorganic aerosols based on two pollution incidences in Nanjing in June 2014. A significant characteristic of air pollution complex with the coexistence of higher concentrations of both PM and ozone is observed. In the earlier stage of the pollution episode, ozone concentra...

Residential air pollution does not modify the positive association between physical activity and lung function in current smokers in the ECRHS study.

Very few studies have examined whether a long-term beneficial effect of physical activity on lung function can be influenced by living in polluted urban areas.

Ozone detoxification of patulin in aqueous solution and cytotoxic evaluation using human hepatic carcinoma cells.

Patulin often contaminates fruits and fruit-base products, which seriously threats the health of consumers. In this study, ozone was used to degrade patulin in aqueous solution, and investigated the cytotoxicity of patulin after ozone detoxification on human hepatic carcinoma cells (HepG2) using MTT assay and apoptosis assay. Patulin was rapidly degraded from 24.59 mg/L to 9.85 mg/L within 180 s by 10.60 mg/L of ozone at a flow rate of 90 mL/min, and reduced by 59.94%. The half maximal inhibitory ...

Ethylenediurea (EDU) mitigates the negative effects of ozone in rice: insights into its mode of action.

Monitoring of ozone damage to crops plays an increasingly important role for the food security of many developing countries. Ethylenediurea (EDU) could be a tool to assess ozone damage to vegetation on field scale, but its physiological mode of action remains unclear. This study investigated mechanisms underlying the ozone-protection effect of EDU in controlled chamber experiments. Ozone sensitive and tolerant rice genotypes were exposed to ozone (108 ppb, 7 h day ) and control conditions. EDU alleviated oz...

Future ozone-related acute excess mortality under climate and population change scenarios in China: A modeling study.

Climate change is likely to further worsen ozone pollution in already heavily polluted areas, leading to increased ozone-related health burdens. However, little evidence exists in China, the world's largest greenhouse gas emitter and most populated country. As China is embracing an aging population with changing population size and falling age-standardized mortality rates, the potential impact of population change on ozone-related health burdens is unclear. Moreover, little is known about the seasonal varia...

Estimation of personal ozone exposure using ambient concentrations and influencing factors.

Evidence is limited regarding whether ambient monitoring can properly represent personal ozone exposure. We conducted a longitudinal panel study to measure personal exposure to ozone using real-time personal ozone monitors. Corresponding ambient ozone concentrations and possible influencing factors (meteorological conditions and activity patterns) were also collected. We used linear mixed-effect models to analyze personal-ambient ozone concentration associations and possible influencing factors. Ambient ozo...

Uptake of ozone and modification of lipids in Betula Pendula pollen.

Pollen allergy risk is modified by air pollutants, including ozone, but the chemical modifications induced on pollen grains are poorly understood. Pollen lipidic extract has been shown to act as an adjuvant to the allergenic reaction and therefore, the modification of lipids by air pollutants could have health implications. Birch pollen was exposed in vitro to ozone to explore the reactivity of O on its surface and on its lipidic fraction. Uptake coefficients of ozone were determined for ozone concentratio...

Inhalation of House Dust and Ozone Alters Systemic Levels of Endothelial Progenitor Cells, Oxidative Stress, and Inflammation in Elderly Subjects.

Ambient air pollution including ozone and especially particulate matter represents important causes of cardiovascular disease. However, there is limited knowledge on indoor air dust with respect to this risk and the potential interactions between dust and ozone. Here, we exposed 23 healthy elderly subjects for 5.5 h, to either clean air, house dust at 275 µg/m3 (diameter < 2.5 µm), ozone at 100 ppb or combined house dust and ozone in a double-blinded randomized cross-over study. The combined house dust an...

Air Pollution and Non-Communicable Diseases: A review by the Forum of International Respiratory Societies' Environmental Committee. Part 2: Air pollution and organ systems.

Although air pollution is well-known to be harmful to the lung and airways, it can also damage most other organ systems of the body. It is estimated that about 500,000 lung cancer deaths and 1.6 million chronic obstructive pulmonary disease (COPD) deaths can be attributed to air pollution, but air pollution may also account for 19% of all cardiovascular deaths and 21% of all stroke deaths. Air pollution has been linked to other malignancies, such as bladder cancer and childhood leukemia. Lung development in...

Effect of VOCs on O and SOA Formation Potential During the Combined Pollution Process in Guangzhou Panyu Atmospheric Composition Station.

An analysis was made by using historical observational data of Guangzhou Panyu Atmospheric Composition Station(GPACS). The results showed that typical haze processes accompanied with high ozone episodes happened during the period from September 2rd, 2011 to September 5th, 2011(P) and the period from June 12th, 2012 to June 15th, 2012(P) respectively. During the two combined pollution processes (P and P), daily visibility ranged from 5.78 km to 6.91 km and from 5.60 km to 9.25 km, and the maximum 8 h Oreache...


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