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02:48 EST 18th January 2019 | BioPortfolio

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Showing "Akorn Provides Second Quarter 2016 Results" PubMed Articles 1–25 of 40,000+

Life sciences licensing deals in the second quarter of 2018: updates and trends.

During the second quarter of 2018, Cortellis Competitive Intelligence registered 985 new deals (excluding mergers and acquisitions) with a total disclosed deal value of USD 19.5 billion as part of its ongoing coverage of licensing activity in the life sciences sector compared to 964 and USD 35.6 billion in the first quarter and 1,104 and USD 13.6 billion in the second quarter of 2017. Total deal value in the second quarter did not quite reach the peak of 2014 (paced by Novartis' USD 16 billion purchase of G...

Asymmetrical endothelial cell migration from in vitro Quarter-Descemet membrane endothelial keratoplasty grafts.

To investigate in vitro central and peripheral corneal endothelial cell (EC) migration from Quarter-Descemet membrane endothelial keratoplasty (Quarter-DMEK) grafts.

Elimination of selected mastitis pathogens during the dry period.

We aimed to evaluate the elimination of 4 different mastitis pathogens, Streptococcus agalactiae, Mycoplasma bovis, Staphylococcus aureus, and Streptococcus uberis, from infected udder quarters during the dry period using quantitative PCR. The second purpose of this study was to evaluate the association between milk haptoglobin (Hp) concentration and the presence of udder pathogens (Strep. agalactiae, Staph. aureus, M. bovis, and Strep. uberis) in udder quarter milk samples before and after dry period. Asep...

Transmission dynamics of Staphylococcus aureus within two Danish dairy cattle herds.

Staphylococcus aureus is a major pathogen causing intramammary infections (IMI) in dairy cattle herds worldwide. Simulation models can be used to investigate the epidemiologic and economic outcomes of different control strategies against IMI. The transmission rate parameter is one of the most influential parameters on the outcomes of these simulation models. Very few studies have estimated the transmission rate parameter and investigated the transmission dynamics of Staph. aureus IMI in dairy cattle herds. ...

The changing landscape of naloxone availability in the United States, 2011 - 2017.

Opioid overdose deaths have been on the rise in the United States since 1999. Naloxone is a competitive opioid antagonist that rapidly reverses opioid overdose. The implementation of naloxone access laws and development of naloxone formulations that can be administered by laypersons have coincided with changes in the landscape of naloxone availability in the United States. Using data from IQVIA's National Prescription Audit we present the number of naloxone prescriptions dispensed quarterly from 2011 throug...

Lower Quarter Y-Balance Test in healthy women 50-79 years old.

The Lower Quarter Y-Balance Test (LQ-YBT), a measure of dynamic balance used in young adults, has not been adequately studied in older women. We determined the reliability, normative values, and relationships to other balance measures for LQ-YBT in women aged 50-79 years. Interrater reliability was strong, and test-retest reliability was moderate to strong. Results by decade showed women 50-59 years had significantly better scores than both older groups. There were moderate positive correlations between s...

Molecular characterization of Corynebacterium diphtheriae isolates in Malaysia between 1981 and 2016.

Sporadic diphtheria cases in Malaysia have remained low in number since the 1990s. However, in 2016 a total of 31 cases were reported nationwide and to investigate this we performed molecular characterization of 30 Corynebacterium diphtheriae isolates collected from 1981 to 2016 using multilocus sequence typing (MLST). C. diphtheriae isolates were identified and biotyped using the API Coryne kit, while the toxigenicity was determined by PCR and the Elek test. All of the 2016 isolates belonged to biotype mit...

Laboratory Trend in Vitamin D Status in Ireland: Dual Concerns about Low and High 25OHD.

Serum 25-hydroxyvitamin D (25OHD) is the pre-eminent estimate of vitamin D status that we have been measuring in a hospital laboratory setting since the 1970s. We previously evaluated the trend in 25OHD results in our laboratory from 1993 to 2013. Using a time series analysis of monthly average 25OHD results the trend was modelled, and this was used to forecast monthly average 25OHD from 2014 to 2016. In this study, all 25OHD results from 2014 to 2016 were retrieved (n = 67,922) and trimmed to 40,307 re...

The effect of individual quarter dry-off in management of subclinical mastitis on udder condition and milk production in organic dairy herds: A randomized field trial.

The objective of the study was to evaluate the effect of individual quarter dry-off in management of subclinical mastitis on clinical development, behavior during milking, and short-term production loss. The study was conducted as a controlled randomized trial in 5 commercial organic dairy herds. Seventy cows meeting the inclusion criteria were randomly allocated to 1 of 2 treatments: individual quarter dry-off (QDO) or continued milking. The inclusion criteria constituted an increase in somatic cell count ...

On the apparent decrease in Olympic sprinter reaction times.

Reaction times of Olympic sprinters provide insights into the most rapid of human response times. To determine whether minimum reaction times have changed as athlete training has become ever more specialized, we analyzed the results from the Olympic Games between 2004 and 2016. The results for the 100 m and 110 m hurdle events show that minimum reaction times have systematically decreased between 2004 and 2016 for both sexes, with women showing a marked decrease since 2008 that eliminated the sex difference...

Increased Presence of Fentanyl in Cocaine-Involved Fatal Overdoses: Implications for Prevention.

After remaining stable from 2010 to 2014, the  rate of cocaine-involved overdose death increased sharply from 2015 to 2016. This study aims to determine the contribution of opioids, and fentanyl in particular, to the increase in cocaine-involved overdose death from 2015 to 2016. Using New York City death certificate data linked to medical examiner toxicology data, we identified all overdose deaths where post-mortem toxicology results were positive for cocaine from 2010 to 2016. We analyzed cocaine-involved...


Differences in results from the new Mayak Worker Dosimetry System (MWDS-2016) vs the previous MWDS-2013 are described. Statistical characteristics are shown for the distribution of accumulated absorbed doses to organs for 8340 workers with bioassay data. Differences in mean values of accumulated doses and their relative standard uncertainties calculated by MWDS-2016 and MWDS-2013 were analysed separately for various types of industrial compounds of plutonium, specifically nitrates, mixtures and oxides. With...

Evaluation of the 2016 ENV57 MetroERM measurement comparison on Cs, Cs and I in air filters.

In 2016, the European Commission's Joint Research Centre organised an interlaboratory comparison exercise on the measurement of Cs, Cs and I in air filters. The exercise was conducted in the frame of the MetroERM EMRP project with code ENV57. This paper describes the context of the interlaboratory measurement comparison, the technical implementation, the air filter measurements performed by the participating laboratories and finally the evaluation of the comparison results. The intercomparison exercise resu...

Improving image quality with model-based iterative reconstruction at quarter of nominal dose in upper abdominal CT.

To evaluate the ability of a model-based iterative reconstruction (MBIR) for improving image quality in upper abdominal CT with quarter of the normal dose, in comparison with adaptive statistical iterative reconstruction (ASiR) at normal dose.

Third-quarter biotech job picture.

Second-quarter biotech job picture.

Changes in public trust in physicians: empirical evidence from China.

Studies examining the trends in public trust in physicians have provided a considerable amount of valuable policy implications for policymakers compared with cross-sectional studies on this topic in many countries. This study investigated changes in public trust in physicians in China based on two cross-sectional national surveys conducted in 2011 and 2016 and identified the determinants of these changes. The results indicated 83.4% of respondents in 2011 reported trust or strong trust in physicians in Chin...

A note on internet use and the 2016 U.S. presidential election outcome.

We use data from the American National Election Studies from 1996 to 2016 to study the role of the internet in the 2016 U.S. presidential election outcome. We compare trends in the Republican share of the vote between likely and unlikely internet users, and between actual internet users and non-users. Relative to prior years, the Republican share of the vote in 2016 was as high or higher among the groups least active online.

Comparative Assessment of Scoring Functions: The CASF-2016 Update.

In structure-based drug design, scoring functions are often employed to evaluate protein-ligand interactions. A variety of scoring functions have been developed so far, and thus some objective benchmarks are desired for assessing their strength and weakness. The comparative assessment of scoring functions (CASF) benchmark developed by us provides an answer to this demand. CASF is designed as a "scoring benchmark", where the scoring process is decoupled from the docking process to depict the performance of s...

Support for vector control strategies in the United States during the Zika outbreak in 2016: The role of risk perception, knowledge, and confidence in government.

Limiting the spread and impact of Zika was a major global priority in 2016, which required a variety of vector control measures. The success of vector control campaigns is varied and often dependent on public or political will. This paper examines the change over time in the United States population's support for vector control and the factors that predicted support for three vector control strategies (i.e., indoor spraying, outdoor spraying, and use of larvacide tablets) during the 2016 Zika outbreak in th...

Burden of Diseases and Injuries in Afghanistan, 1990-2016: Findings From the Global Burden of Disease 2016 Study.

Afghanistan is one of the low-income countries in the Eastern Mediterranean Region with young population and myriad of healthcare needs. We aim to report the burden of diseases and injuries in Afghanistan between 1990 and 2016.

The prevalence and years lived with disability caused by low back pain in China, 1990 - 2016: findings from the global burden of disease study 2016.

The aim of this work was to quantify the prevalence and years lived with disability (YLDs) caused by low back pain (LBP) in China from 1990 to 2016. Data from the GBD 2016 (Global Burden of Diseases, Injuries, and Risk Factors Study 2016) were used. We analyzed the age-sex-province-specific prevalence and YLDs for LBP of 33 provinces/regions in China. Comparisons were made with the data retrieved from the 1990 GBD study. We estimated that 5.45x10 individuals had LBP in 1990, which rose to 6.73x10 in 2016. T...

A Comparison of the National Football League's Annual National Football League Combine 1999-2000 to 2015-2016.

Fitzgerald, CF and Jensen, RL. A Comparison of the National Football League's annual National Football League combine 1999-2000 to 2015-2016. J Strength Cond Res XX(X): 000-000, 2018-The purpose of this study was to determine if elite football players are becoming bigger, faster, and stronger over the past decade by analyzing individual performances at the National Football League's (NFL) Combine. This study was conducted with (N = 1,263) subjects from the 1999-2000 (99-00) NFL Combines (n = 635) and the 20...

Alberta wildfire 2016: Apt contribution from anomalous planetary wave dynamics.

In May-June 2016 the Canadian Province of Alberta suffered one of the most devastating wildfires in its history. Here we show that in mid-April to early May 2016 the large-scale circulation in the mid- and high troposphere of the middle and sub-polar latitudes of the northern hemisphere featured a persistent high-amplitude planetary wave structure dominated by the non-dimensional zonal wave number 4. The strongest anticyclonic wing of this structure was located over western Canada. In combination with a ver...

Medicaid/CHIP Participation Reached 93.7 Percent Among Eligible Children In 2016.

Children's participation in Medicaid and the Children's Health Insurance Program (CHIP) rose by 5 percentage points between 2013 and 2016. As a result, 1.7 million fewer Medicaid/CHIP-eligible children were uninsured in 2016. Participation was lower among adults than among children, and nearly 6 million Medicaid-eligible adults were uninsured in 2016.

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