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PubMed Journals Articles About "Alabama Bill Would Require Grown Protein Carry Label" RSS

20:26 EDT 20th September 2019 | BioPortfolio

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Showing "Alabama bill would require grown protein carry label" PubMed Articles 1–25 of 20,000+

Consumers' Responses To Surprise Medical Bills In Elective Situations.

A surprise medical bill is a bill from an out-of-network provider that was not expected by the patient or that came from an out-of-network provider not chosen by the patient. We investigated consumers' hospital choices after receipt of surprise out-of-network medical bills in an elective situation, using a large national sample of medical claims for obstetric patients with two deliveries covered by employer-sponsored health insurance in 2007-14. We found that 11 percent of mothers experienced a surprise ou...


Evaluation of "Stop the Bleed" training among K-12 faculty and staff in Alabama.

To evaluate "Stop the Bleed" (STB) training among/K12 personnel in an Alabama school system, and to assess participants' perceived readiness to train peers in STB methods.

Identifying Protein Conformational Dynamics Using Spin-label ESR.

Spin-label electron spin resonance (ESR) has emerged as a powerful tool to characterize protein dynamics. One recent advance is the development of ESR for resolving dynamical components that occur or coexist during a biological process. It has been applied to study the complex structural and dynamical aspects of membranes and proteins, such as conformational changes in protein during translocation from cytosol to membrane, conformational exchange between equilibria in response to protein-protein and protein...


Nitrogen-dependent metabolic regulation of lipid production in microalga Scenedesmus vacuolatus.

Microalga Scenedesmus vacuolatus exhibited maximum growth, protein and carbohydrate contents at 10.0 mM concentration of nitrate, 1.0 mM of glutamate nitrogen and at C/N ratio (12 mM acetate+10 mM nitrate). However, these cell constituents showed the highest values in the C+N grown cells, but the lipid content was found to be the highest glutamate grown cells. FTIR analysis of Lipid/Carbohydrate and Lipid/Protein ratio and flow cytometric analysis of neutral lipids revealed higher lipid content in t...

Tuning the "violin" of protein kinases: The role of dynamics-based allostery.

The intricacies of allosteric regulation of protein kinases continue to engage the research community. Allostery, or control from a distance, is seen as a fundamental biomolecular mechanism for proteins. From the traditional methods of conformational selection and induced fit, the field has grown to include the role of protein motions in defining a dynamics-based allosteric approach. Harnessing of these continuous motions in the protein to exert allosteric effects can be defined by a "violin" model that foc...

Cysteine/cystine-rich undenatured whey protein supplement in patients' pressure ulcers outcomes: an open label study.

The prevalence and costs associated with treating pressure ulcers (PU) are at high levels. Frequently, PUs heal slowly or not at all, which may be due to the patient's catabolic state which may include protein energy malnutrition. The objective of this open label clinical trial was to improve healing rates by providing patients with a patented, high-quality protein containing all essential amino acids to ensure positive nitrogen balance. An additional benefit of this protein is the delivery of bioavailable ...

An insightful recollection for predicting protein subcellular locations in multi-label systems.

A systematic introduction has been presented for the recent advances in predicting protein subcellular localization in the multi-label systems, where the constituent proteins may simultaneously occur or move between two or more location sites and hence have exceptional biological functions worthy of our special notice. All the predictors included in this review each have a user-friendly web-server, by which the majority of experimental scientists can very easily acquire their desired data without the need t...

An insightful recollection for predicting protein subcellular locations in multi-label systems.

A systematic introduction has been presented for the recent advances in predicting protein subcellular localization in the multi-label systems, where the constituent proteins may simultaneously occur or move between two or more location sites and hence have exceptional biological functions worthy of our special notice. All the predictors included in this review each have a user-friendly web-server, by which the majority of experimental scientists can very easily acquire their desired data without the need t...

Advances in Current Diabetes Proteomics: From the Perspectives of Label-free Quantification and Biomarker Selection.

Due to its prevalence and negative impacts on both economy and society, the diabetes mellitus (DM) has emerged as a worldwide concern. In light of this, the label-free quantification proteomics (LFQ) and diabetic marker selection methods have been applied to elucidate the underlying mechanisms associated with insulin resistance, explore novel protein biomarkers, and discover innovative therapeutic protein targets.

Call for Action: Benzodiazepine Prescription Prevalence Analysis Shows Off-Label Prescription in One in Eleven Citizens.

Benzodiazepines have a good safety profile. Nevertheless, off-label use of these drugs may increase the risk of falls, dependence, and memory loss. Off-label prescription use is not highly prevalent. Studies have not researched the factors that influence off-label prescription use. We aim to identify the prevalence of off-label use of benzodiazepines in Barcelona and explore sociodemographic factors that may be involved for professionals and patients.

The use of off-label medications in substance abuse treatment programs.

Substance use disorder (SUD) treatment centers serve a population of clients who have diverse needs, and may desire or require access to varied treatments while seeking care for their SUDs. While pharmacotherapies have increased in popularity for the treatment of SUDs, adoption rates do remain quite low. But a wider array of pharmacotherapies has become available in recent years which may shift the trend. This article helps shed light on how variations in SUD treatment centers develop and persist with regar...

Scattered light imaging enables real-time monitoring of label-free nanoparticles and fluorescent biomolecules in live cells.

Simultaneously monitoring label-free nanoparticles (NPs) and fluorescent biomolecules inside live cell in real time is challenging because both imaging methods require different instrumentation and measuring principles. Here we report a novel scattered light imaging (SLi) technique that allows label-free NP to be monitored using a conventional confocal microscope. The method shows a high spatial resolution and can distinguish label-free silver nanoparticles (AgNPs) with a 10 nm size difference in live cells...

Control of bill-grasping aperture with varying food size in crows.

Grasping movement in primates is known to be a visually guided behavior and the aperture of hand opening is adjusted to the target size on the basis of visual information. The analogous behavior can be found in birds, called 'pecking', consisting of head-reaching and bill-grasping. Bill-grasping has been investigated mainly in pigeons and an aperture adjustment as seen in primates has been reported. This study focused on kinematics of pecking in crows, known to possess dexterous visuomotor skills, to examin...

Label-specific feature selection and two-level label recovery for multi-label classification with missing labels.

In multi-label learning, each instance is assigned by several nonexclusive labels. However, these labels are often incomplete, resulting in unsatisfactory performance in label related applications. We design a two-level label recovery mechanism to perform label imputation in training sets. An instance-wise semantic relational graph and a label-wise semantic relational graph are used in this mechanism to recover the label matrix. These two graphs exhibit a capability of capturing reliable two-level semantic ...

Peptide-to-Protein Summarization: An Important Step for Accurate Quantification in Label-Based Proteomics.

Quantitative MS/MS-based measurements are assessed at the peptide spectrum level and substantial variance is frequently observed for any given protein. Protein quantification requires a peptide-to-protein summarization step. This important step has been little investigated and most strategies only rely on quantitative spectrum values, ignoring a wealth of additional feature information is available for peptide spectra.In this chapter, we discuss summarization methods that can be applied for label-based pro...

A Double Support Layer for Facile Clean Transfer of 2D Materials for High-Performance Electronic and Optoelectronic Devices.

Clean transfer of 2D materials grown by chemical vapor deposition is critical for their application in electronics and optoelectronics. While rosin can be a support layer for the clean transfer of graphene grown on Cu, it has not been usable for the transfer of 2D materials grown on noble metals or for large-area transfer. Here, we report a poly(methyl methacrylate) (PMMA)/rosin double support layer that enables facile ultraclean transfer of large-area 2D materials grown on different metals. The bottom rosi...

Linguistic conventionality and the role of epistemic reasoning in children's mutual exclusivity inferences.

To interpret an interlocutor's use of a novel word (e.g., "give me the papaya"), children typically exclude referents that they already have labels for (like an "apple"), and expect the word to refer to something they do not have a label for (like the papaya). The goal of the present studies was to test whether such mutual exclusivity inferences require children to reason about the words their interlocutors know and could have chosen to say: e.g., If she had wanted the "apple" she would have asked for it (s...

On-label compared to off-label four-factor prothrombin complex concentrate use: a retrospective, observational study.

Four-factor prothrombin complex concentrate (4F-PCC) is US Food and Drug Administration approved for the urgent reversal of coagulation factor deficiency induced by a vitamin K antagonist complicated by acute major bleeding or in situations in which invasive procedures are urgently needed. Although recent evidence suggests the superiority of 4F-PCC over plasma for on-label indications, the off-label use of 4F-PCC has not been rigorously studied.

Label-free detection of biotoxins via a photo-induced force infrared spectrum at the single-molecular level.

There is an increasing urge to investigate facile solutions for monitoring biotoxins, which are a major concern in both the food safety and the anti-terrorism fields. Current techniques, such as immunochromatographic tests (ICT), enzyme-linked immunosorbent assay (ELISA) and mass spectrometry, are still insufficient to satisfy the needs for fast, label-free, and ultra-sensitive detection. Herein, a single-molecular, label-free detection method based on atomic force microscopy was employed to solve the above...

Label-free target identification in drug discovery via phenotypic screening.

Phenotypic screening has demonstrated its advantage in the discovery of first-in-class therapeutics, whereas target-based screening has showed strength for follower drugs. Owing to the unbiased nature of phenotypic screening, novel druggable proteins can be uncovered by target identification. Chemical label-free target identification methods can eliminate the functionalization step of an original bioactive compound. Herein, we summarize recent advances in the development of label-free target identification ...

In silico prediction of endocrine disrupting chemicals using single-label and multi-label models.

Endocrine disruption (ED) has become a serious public health issue and also poses a significant threat to the ecosystem. Due to complex mechanisms of ED, traditional in silico models focusing on only one mechanism are insufficient for detection of endocrine disrupting chemicals (EDCs), let alone offering an overview of possible action mechanisms for a known EDC. To remove these limitations, in this study both single-label and multi-label models were constructed across six ED targets, namely AR (androgen rec...

Off-label prescriptions of drugs used for the treatment of Crohn's disease or ulcerative colitis.

Off-label prescribing is encountered across various fields of medicine and creates alternative treatment options, but is associated with unknown safety risks. The use of off-label drugs for the treatment of patients with inflammatory bowel diseases (IBD) has not been characterised before.

Associations of Statewide Legislative and Administrative Interventions With Vaccination Status Among Kindergartners in California.

California implemented 3 interventions to increase uptake of vaccines. In 2014, Assembly bill 2109 tightened requirements for obtaining a personal belief exemption. A 2015 campaign provided educational materials to school staff on the proper application of conditional admission for kindergartners who were not up to date on required vaccinations. In 2016, Senate bill 277 eliminated personal belief exemptions. Prior research has not evaluated these 3 interventions together with regard to the vaccination statu...

(Don't) look here!: The effect of different forms of label added to fashion advertisements on women's visual attention.

The present study used eye tracking technology to experimentally investigate the effect of different label formats on women's visual attention to fashion magazine advertisements, and its relationship with body dissatisfaction and appearance comparison. Participants were 260 female undergraduate students whose eye movements were recorded while viewing three thin-ideal fashion advertisements with one of five different forms of label added: no label, disclaimer label (indicating image had been digitally altere...

Protein binding kinetics quantification via coupled plasmonic-photonic resonance nanosensors in generic microplate reader.

Almost no analytical assays, either colorimetric or fluorescence assays, for generic microplate readers is capable of dynamic measurements of protein-protein binding or the quantification of kinetic association and dissociation constants of protein interactions. On the other hand, protein binding kinetics quantification can be uniquely done on special expensive surface plasmon resonance (SPR) sensing equipment. Here we report the integration of coupled plasmonic-photonic resonance nanosensors in standard 96...


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