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PubMed Journals Articles About "Anacor Strikes Acne Deal With Medicis" RSS

23:32 EDT 19th September 2018 | BioPortfolio

Anacor Strikes Acne Deal With Medicis PubMed articles on BioPortfolio. Our PubMed references draw on over 21 million records from the medical literature. Here you can see the latest Anacor Strikes Acne Deal With Medicis articles that have been published worldwide.

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Showing "Anacor Strikes Acne Deal With Medicis" PubMed Articles 1–25 of 535

Skin microneedling for acne scars associated with pigmentation in patients with dark skin.

Acne is very common skin condition. Most patients with acne will have a degree of scarring as a result of their acne. In patients with darker skin color the scarring can be further complicated by hyperpigmentation. Several treatment options can be used to improve acne scarring, however the problem of post acne hyperpigmentation is not often addressed. This study especially focus on the treatment of pigmented post acne scarring using skin microneedling.


Severe Acne in Monozygotic Twins Treated with Photodynamic Therapy.

Acne is a common skin disease in adolescence. It is a chronic inflammatory disease of the pilosebaceous units, which mainly occurs on the face and upper parts of the trunk. Based on severity of the lesions, acne can be mild, moderate or severe. Severe acne is usually featured with a protracted course and residual scars. Photodynamic therapy (PDT) has been demonstrated to be effective in severe acne recently. We report a case of monozygotic twins with severe acne who were successfully treated with PDT.

Currently Constrained, Dermatologists Are Ready for New Acne Therapies.

Acne is the most common skin condition in the United States, affecting 50 million Americans annually. The disease's severity can range from mild to severe, with approximately 20% of people with acne experiencing moderate to severe disease.


Platelet-Rich Plasma Augments Subcision in Atrophic Acne Scars: A Split-Face Comparative Study.

Acne has a prevalence of 90% among adolescents. Facial scarring affects 75% of patients. Autologous platelet-rich plasma (PRP) is a novel treatment option for acne scar management and can be used as an adjuvant to acne scar revision procedures. Owing to its remodeling properties, PRP when used as an adjuvant reduces the total number of sittings.

Efficacy, Safety, and Tolerability of Topical Dapsone Gel, 7.5% for Treatment of Acne Vulgaris by Fitzpatrick Skin Phototype.

Acne vulgaris (acne) is prevalent in individuals with skin of color, often with more frequent sequelae than in patients with lighter skin color. It is important to determine if there are also differences in response to medications.

Is depression screening in acne patients critical?: reply from authors.

We thank Unrue and Feldman1 for raising an important question of whether depression screening is indicated in acne patients. While we concluded in our study that "it is critical that physicians monitor mood symptoms in patients with acne", we did not recommend formal screening for depression in acne patients and believe it is important to draw a distinction between a formal screening program vs. symptom monitoring. This article is protected by copyright. All rights reserved.

Case Reports of Acne and Homeopathy.

Acne vulgaris is a self-limiting disorder of the pilosebaceous unit. The aesthetic aspect of the disorder may provoke depression and diminish the quality of life. A number of agents are used for acne treatment, e.g., retinoids, antibiotics, benzoic acid, azelaic acid, and hormones. These agents have side-effects, sometimes severe ones.

Short-term exposure of human sebocytes to 13-cis retinoic acid induces acnegenic changes.

Acne vulgaris is the most common skin disorder and contributes an estimated 0.29% of the global burden of disease. The pathophysiology of acne involves excess sebum production and altered lipid composition by the sebaceous glands, follicular hyperkeratinization, bacterial colonization by Cutibacterium acnes (C. acnes), and perifollicular inflammation. 13-cis Retinoic Acid (13-cis RA), also known as isotretinoin, is the only acne therapy that targets all four pathologic mechanisms and is often prescribed to ...

Update on acne scar treatment.

Acne vulgaris and postacne scarring are common in the general population. Even after lesions have resolved, scarring can lead to detrimental psychologic effects and can negatively impact patients' quality of life. Fortunately, there have been several recent advances in therapeutic options to treat acne scarring. This article discusses these treatments with a focus on microneedling, lasers, chemical peels, and dermal fillers.

Clinical Experience With Once-Daily Dapsone Gel, 7.5% Monotherapy in Patients With Acne Vulgaris.

Dapsone gel, 7.5% is a topical medication approved for acne in patients aged 12 years and older. Clinical trials have demonstrated the safety and efficacy of once-daily dapsone gel, 7.5% in patients with moderate acne.

A Qualitative Investigation of the Impact of Acne on Health-Related Quality of Life (HRQL): Development of a Conceptual Model.

The negative impact of acne on aspects of health-related quality of life (HRQL) has been demonstrated in many quantitative studies; however, there has been relatively little qualitative research exploring the impact of acne and the use of topical treatment. The study aimed to explore the impact of moderate-severe acne on HRQL in adolescents and adults with inflammatory and non-inflammatory lesions and to develop a conceptual model to illustrate the impact. In addition, the study aimed to identify the attrib...

Cutibacterium acnes (Propionibacterium acnes) and acne vulgaris: a brief look at the latest updates.

While the commensal bacterium Propionibacterium acnes (P. acnes) is involved in the maintenance of a healthy skin, it can also act as an opportunistic pathogen in acne vulgaris. The latest findings on P. acnes shed light on the critical role of a tight equilibrium between members of its phylotypes and within the skin microbiota in the development of this skin disease. Indeed, contrary to what was previously thought, proliferation of P. acnes is not the trigger of acne as patients with acne do not harbour...

Circular RNA expression profile analysis of severe acne by RNA-seq and bioinformatics.

Acne is a common chronic skin disease with a multifactorial etiology and pathogenesis. Recently, circular RNAs (circRNAs) have been identified as a key factor in regulating gene expression through circRNA-miRNA-mRNA networks in many biological processes and human diseases. However, the circRNAs expression in patients with acne is still unknown.

Characterisation of Cutibacterium acnes phylotypes in acne and in vivo exploratory evaluation of Myrtacine.

Our main objective was to compare Cutibacterium acnes (C. acnes) skin colonisation in patients with mild to moderate acne versus healthy controls and secondly, to evaluate a Myrtacine -based cream on C. acnes total population and antibioresistant Cutibacteria in patients with acne.

Skin Confident: A skin health and acne educational intervention to improve Acne Quality of Life measures in adolescents.

Is depression screening in acne patients critical?

Vallerand et al make an interesting observation of an increased rate of major depressive disorder (MDD) in acne patients. They conclude, "it is critical that physicians monitor mood symptoms in patients with acne." [1] An increased rate of MDD, however, does not necessarily mean screening is indicated. Screening may be indicated if benefits exceed risks and costs, but that is not yet established. [2-4] This article is protected by copyright. All rights reserved.

An Acne Survey from the World's Largest Annual Gathering of Twins.

Surveying identical twins allows us to qualitatively separate genetic and environmental factors that may contribute to acne severity.

Who Is Accountable When Patients Do Not Achieve Successful Treatment for Their Acne?

Acne vulgaris (AV) is a very common inflammatory facial disorder that is complex in its pathophysiology, heterogenous in clinical presentation, and affects children and adults of all ethnicities, races, and skin types.

A Low Glycemic Index and Glycemic Load Diet Decreases Insulin-like Growth Factor-1 among Adults with Moderate and Severe Acne: A Short-Duration, 2-Week Randomized Controlled Trial.

A high glycemic index (GI) and glycemic load (GL) diet may stimulate acne proliferative pathways by influencing biochemical factors associated with acne. However, few randomized controlled trials have examined this relationship, and this process is not completely understood.

Topical Vehicle Formulations in the Treatment of Acne.

Topical treatment is the mainstay of acne therapy. The most commonly prescribed topical medications for acne include benzoyl peroxide, clindamycin, and retinoids. Despite their effectiveness in treating mild to moderate acne vulgaris, these topical medications are found to be irritating, and are historically associated with poor tolerability and diminished patient adherence. Thus, choosing the right formulation that will be effective and well tolerated is essential. Novel formulations that optimize drug con...

Unilateral acne after facial palsy.

We describe a case of unilateral acne which appeared after an episode of facial nerve palsy. An 18-year-old female patient presented with papules and pustules predominantly located on the side where the facial paralysis occurred. The patient suffered right facial paralysis, which was treated with prednisone and kinesiotherapy with massages, electrostimulation, and infrared light. Two weeks later, acne lesions appeared in the area affected by the paralysis. As suggested in other cases of paralysis, including...

The Role of the Physician in Patient Perceptions of Barriers to Primary Adherence With Acne Medications.

Primary nonadherence with acne medications is high but commonly underreported to prescribing physicians.

Frequency of Treatment Switching for Spironolactone Compared to Oral Tetracycline-Class Antibiotics for Women With Acne: A Retrospective Cohort Study 2010-2016.

Long-term oral antibiotic use in acne may be associated with a variety of adverse effects including antibiotic resistance, pharyngitis, inflammatory bowel disease, and breast and colon cancer. Spironolactone may represent an effective and safe alternative to oral antibiotics for women with moderate to severe acne, however comparative studies are lacking.

Acne prevalence in 9 to 14-year-old old patients attending pediatric ambulatory clinics in Italy.

Acne vulgaris is a chronic inflammatory skin disease of the pilosebaceous follicles that affects patients of all ages with a younger onset being more common than in the past.

pH and Acne.

Acne is based on a complex, multifactorial pathophysiology beginning with a microcomedo. Comedogenesis involves follicular hyperproliferation and disturbed keratinization, hyperseborrhea and hyperplasia of sebaceous glands as well as disturbances in skin microbiome. Acne is treated with antibiotics, retinoids, keratolytics, hormonal and anti-inflammatory agents. Efficacy and side effects of given medications are well known. The uppermost layer of the stratum corneum is acidic. The low pH provides protection...


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