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00:42 EDT 24th March 2019 | BioPortfolio

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Showing "Ascendis Pharma Reports Third Quarter 2018 Financial Results" PubMed Articles 1–25 of 46,000+

Life sciences licensing deals in the second quarter of 2018: updates and trends.

During the second quarter of 2018, Cortellis Competitive Intelligence registered 985 new deals (excluding mergers and acquisitions) with a total disclosed deal value of USD 19.5 billion as part of its ongoing coverage of licensing activity in the life sciences sector compared to 964 and USD 35.6 billion in the first quarter and 1,104 and USD 13.6 billion in the second quarter of 2017. Total deal value in the second quarter did not quite reach the peak of 2014 (paced by Novartis' USD 16 billion purchase of G...

Too soon to worry? Longitudinal examination of financial planning for retirement among Spanish aged workers.

The present study analyzes the relationship between three distal antecedents-financial literacy, confidence in retirement, and economic well-being-and financial planning for retirement evaluated at two different times. We used longitudinal data with repeated measures of financial planning for retirement obtained from a sample (N = 269) of active Spanish workers aged 45-62 years. The results confirm that self-perceived financial knowledge, confidence in retirement, and economic well-being are associated with...

Pharma APMs: Can the Industry Learn To Play Well With Others?

The alternative payment model (APM) is a nontraditional financial arrangement that rewards health care providers who deliver cost-effective, high-quality care. Now we are facing the possibility that pharmaceutical manufacturers and insurers will embrace APMs as a payment mechanism in some situations.

Task-irrelevant financial losses inhibit the removal of information from working memory.

The receipt of financial rewards or penalties - though task-irrelevant - may exert an obligatory effect on manipulating items in working memory (WM) by constraining a forthcoming shift in attention or reinforcing attentional shifts that have previously occurred. Here, we adjudicate between these two hypotheses by varying - after encoding- the order in which task-irrelevant financial outcomes and cues indicating which items need to be retained in memory are presented (so called retrocues). We employed a "wha...

Does financial openness increase environmental degradation? Fresh evidence from MERCOSUR countries.

This article researches the impact of financial openness on environmental degradation in the MERCOSUR countries over the time spanning from 1980 to 2014. The Panel Autoregressive Distributed Lag (PARDL), in the form of Unrestricted Error Correction Model (UECM), was computed with the purpose of decomposing the total effects of variables in their short- and long-run ones. The results of short-run impacts and elasticities of PARDL model showed that the financial openness increases the CO emissions both in the...

Financial hardship and risk of suicide among U.S. Army personnel.

Financial stress has been frequently identified as a risk factor for suicidal behavior, both in military and civilian groups. However, it remains unclear to what degree financial stress may be associated independently with suicide behavior when accounting for other risk factors. This study examined data on suicide and suicide attempt cases in the Department of Defense Suicide Event Report compared with service members who did not have recent suicide behavior. The resulting multinomial regression analysis fo...

Objective and subjective financial status and mortality among older adults in China.

The association between financial status and mortality in older adults is well documented. However, it is unclear whether the association may vary by objective and subjective indicators of financial status. To examine this issue, we used the latest four waves (2005, 2008/2009, 2011/2012, and 2014) of the Chinese Longitudinal Healthy Longevity Survey (CLHLS) of community-residing adults aged 65 and older (n = 25,954). Financial status was assessed using eight objective, subjective, and culturally-oriente...

A meeting Report on the 2018 annual meeting of ASBMR-Clinical practice of the osteoporosis-.

In the 2018 ASBMR annual meeting, many important results were reported, showing the effects of anti-osteoporotic drugs already focusing on bone quality and the concept of "treat-to-target", although there were few big topics on novel drugs. However, some reports on new drugs, such as probiotics and SARM(selective androgen receptor modulator), did draw attention.

Financial toxicity in cancer care: Prevalence, causes, consequences, and reduction strategies.

Financial toxicity is the adverse impact of a cancer diagnosis on a patient's financial well-being resulting from direct or indirect costs. Potential consequences of financial toxicity include material loss, psychological distress, and/or maladaptive coping strategies. This review will summarize the prevalence, causes, and consequences of financial toxicity, with an emphasis on strategies to anticipate and reduce its burden. Improvement will require multilevel, coordinated efforts between stakeholders inclu...

A novel financial risk assessment model for companies based on heterogeneous information and aggregated historical data.

The financial risk not only affects the development of the company itself, but also affects the economic development of the whole society; therefore, the financial risk assessment of company is an important part. At present, numerous methods of financial risk assessment have been researched by scholars. However, most of the extant methods neither integrated fuzzy sets with quantitative analysis, nor took into account the historical data of the past few years. To settle these defects, this paper proposes a n...

Relationships between Financial Toxicity and Symptom Burden in Cancer Survivors: A Systematic Review.

Financial toxicity (FT) is used to describe the financial distress/hardship associated with cancer and its treatment.

The impact of financial development and economic growth on renewable energy consumption: Empirical analysis of India.

This current study investigates the impact of financial development and economic growth on renewable energy consumption in India. Annual time series data is used to cover the period 1971-2015. A long-run equilibrium relationship is confirmed among the variables of financial development, renewable energy consumption and economic growth by the Maki (2012) cointegration test under five structural breaks in the series. Dynamic ordinary least squares (DOLS) estimation results suggest statistically significant an...

Review of "Pilot Study to Evaluate the Safety, Feasibility, and Financial Implications of a Postoperative Telemedicine Program" by Nikolian VC et al in Ann Surg 268: 700-707, 2018.

Financial development and environment in South Asia: the role of institutional quality.

The paper investigates the effect of financial development and institutional quality on the environment in South Asia. Other determinants of environmental quality included are economic growth, energy consumption, FDI, trade openness and institutional quality. For empirical analysis, panel data is used for the period 1984 to 2015. The estimated results indicate that Environmental Kuznet Curve (EKC) hypothesis holds in South Asia, i.e., environment first deteriorates with economic development and then it star...

Cancer survivorship care plans, financial toxicity, and financial planning alleviating financial distress among cancer survivors.

Concomitant with the increasing use of cancer care plans has been an increasing awareness of the potential for oncology care to result in long-term financial burdens and financial toxicity. Cancer survivors can benefit from information on support and resources to help them navigate the challenges after acute cancer treatment. While cancer survivorship plans could be a vehicle for patients to receive information on how to mitigate financial toxicity, cancer survivorship plans have typically not dealt with th...

Asymmetrical endothelial cell migration from in vitro Quarter-Descemet membrane endothelial keratoplasty grafts.

To investigate in vitro central and peripheral corneal endothelial cell (EC) migration from Quarter-Descemet membrane endothelial keratoplasty (Quarter-DMEK) grafts.

EHJ 2018 Editorial Board Meeting: With EHJ now the highest-ranking cardiology journal in the world, Mark Nicholls reports from the publication's 2018 annual board meeting.

Financial Behaviors, Couple-Level Conflict, and Adolescent Relationship Abuse: Longitudinal Results From a Nationally Representative Sample.

Financial disagreements have been identified as a severe source of discord in adult relationships, yet limited work has considered whether financial considerations contribute to conflict among younger samples. Drawing on longitudinal data from a nationally representative sample of adolescents, the current investigation examined the extent to which money lending practices, feelings of financial resentment, and exposure to economic control contribute to couple-level interactions, and in turn, to conflict that...

Back from the Dead. ACA Exchange Market Looking Healthy, Hale, and Competitive.

The brighter outlook for 2019 is what happens when the learning curve starts to flatten out. Remember, this market has only existed for five years. Margins over the past six months have exceeded even pre-ACA levels, and loss ratios reached new lows in the second quarter of 2018.

Is Informal Financial Aid Good for Health? Evidence from Kyrgyzstan, a Low-Income Post-Socialist Nation in Eurasia.

The importance of social capital and economic advantage for health is well established in literature. The relationship between health and social capital through informal financial aid is less understood. Using representative data (N = 7,474), authors explored an association between informal financial aid and health satisfaction in Kyrgyzstan, a post-socialist low-income country in Eurasia. Multilevel modeling revealed significant associations between informal aid and health. Cross-level interactions between...

Transmission dynamics of Staphylococcus aureus within two Danish dairy cattle herds.

Staphylococcus aureus is a major pathogen causing intramammary infections (IMI) in dairy cattle herds worldwide. Simulation models can be used to investigate the epidemiologic and economic outcomes of different control strategies against IMI. The transmission rate parameter is one of the most influential parameters on the outcomes of these simulation models. Very few studies have estimated the transmission rate parameter and investigated the transmission dynamics of Staph. aureus IMI in dairy cattle herds. ...

The (doubtful) role of financial reward in obedience to authority.

The Milgram experiments are among the most well-known and important in the history of psychology. Since first published, there have been countless discussions held on the subject of what factors induce people to exhibit extreme obedience towards authority. One such potential factor, not yet explored empirically, is the receipt in advance of financial gratification by a study participant. In our experiment we compare obedience among participants in classic Milgram paradigm conditions with obedience in a situ...

Initial Validation of the Dyadic Coping Inventory for Financial Stress.

Financial stress can have a detrimental impact on a couple's relationship but there is no validated instrument to assess the way couples cope with financial stress. This study sought to validate the Dyadic Coping Inventory for Financial Strain (DCIFS), an adaptation of the Dyadic Coping Inventory to financial stressors, with self-report data collected from 132 heterosexual couples seeking couple and/or family therapy services. Confirmatory Factor Analysis results supported a 23-item version consisting of th...

Modeling the non-linear relationship between financial development and energy consumption: statistical experience from OECD countries.

The linkage between financial development and energy consumption is widely investigated in the literature. However, the non-linear relationship between financial development and energy demand is still under debate. Therefore, this study aims to examine the non-linear relationship between financial development, economic growth, and energy consumption in OECD countries. The study uses the Driscoll-Kraay standard errors panel regression model for spanning from 1980 to 2016. The empirical findings indicate that...

Do government expenditure and financial development impede environmental degradation in Venezuela?

Environmental degradation is causing global warming, which is of the utmost concern to both physical and social scientists. A number of potential determinants of environmental degradation are analysed in the literature. This study examines the role of government expenditure and financial development in environmental degradation in the context of the environmental Kuznets curve (EKC) hypothesis for the Venezuelan economy. Time series data have been analysed for this purpose. The long-term relationship betwee...

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