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PubMed Journals Articles About "Beech Tree Labs Pharmaceuticals Healthcare Deals Alliances Profile" RSS

04:22 EST 11th December 2018 | BioPortfolio

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Showing "Beech Tree Labs Pharmaceuticals Healthcare Deals Alliances Profile" PubMed Articles 1–25 of 7,300+

Hospital purchasing alliances: Ten years after.

Most hospitals outsource supply procurement to purchasing alliances, or group purchasing organizations (GPOs). Despite their early 20th century origin, we lack both national and trend data on alliance utilization, services, and performance. The topic is important as alliances help hospitals control costs, enjoy tailwinds from affiliated regional/local alliances, and face headwinds from hospital self-contracting and criticism of certain business practices.


Seasonal Alterations in Organic Phosphorus Metabolism Drive the Phosphorus Economy of Annual Growth in Trees on P-Impoverished Soil.

Phosphorus (P) is one of the most important macronutrients limiting plant growth and development, particularly in forest ecosystems such as temperate beech () forests in Central Europe. Efficient tree internal P cycling during annual growth is an important strategy of beech trees to adapt to low soil-P. Organic P (P) is thought to play a decisive role in P cycling, but the significance of individual compounds and processes has not been elucidated. To identify processes and metabolites involved in P cycling ...

Iodine distribution and cycling in a beech (Fagus sylvatica) temperate forest.

Radioiodine is of health concerns in case of nuclear events. Possible pathways and rates of flow are essential information for risk assessment. Forest ecosystems could influence the global cycle of long-lived radioiodine isotope (I) with transfer processes similar to stable isotope (I). Understanding iodine cycling in forest involves study of the ecosystem as a whole. In this context, we determined the I contents and distribution in soil, tree compartments and atmospheric inputs during a three years in situ...


Assessment of 83 pharmaceuticals in WWTP influent and effluent samples by UHPLC-MS/MS: Hourly variation.

The removal efficiency of pharmaceuticals in wastewater treatment plants (WWTPs) is variable and some of these compounds pass these plants almost intact and others presenting a removal efficiency close to 100%. Their incomplete removal results in a continuous discharge of pharmaceuticals into the environment. To assess the profile of contamination of influents and effluents over a day, a set of 83 pharmaceuticals were evaluated hourly in a WWTP in Leiria, Portugal. The composite samples of the influent and ...

The prevalence of persistence and related health status: An analysis of persistently high healthcare costs in the short term and medium term.

Understanding whether high healthcare costs for individuals persist over time is critical for the development of policies that aim to reduce the prevalence of high cost patients. And while high healthcare costs will occur in any given year based on the prevalence of certain morbidities and acute conditions, a large random component of the distribution means that it is rarely the same people driving the bulk of healthcare expenditures. Using administrative data for over 250,000 Australian residents for the y...

Oxygen isotopes in tree rings are less sensitive to changes in tree size and relative canopy position than carbon isotopes.

Stable isotopes ratios in tree rings have become an important proxy for paleoclimatology, particularly in temperate regions. Yet, temperate forests are often characterized by heterogeneous stand structures, and the effects of stand dynamics on carbon (δ C) and oxygen isotope ratios (δ O) in tree rings are not well explored. In this study we investigated long-term trends and offsets in δ O and δ C of Picea abies and Fagus sylvatica in relation to tree age, size and distance to the upper canopy at seven t...

Tree species affects the concentration of total mercury (Hg) in forest soils: Evidence from a forest soil inventory in Poland.

This study was performed to test the hypothesis that tree species significantly affects mercury (Hg) sequestration in forest soils. We analyzed the effect of seven dominant tree species (Scots pine, black alder, Norway spruce, silver birch, deciduous oak, silver fir, and European beech on the concentrations and pools of Hg in a range of forest soils in Poland. We set up 277 sample plots representing dominant tree species in Poland. Soil samples were taken and analyzed for total Hg content, soil texture, and...

The potential of the tree water potential.

Non-invasive quantification of tree water potential is one of the grand challenges for assessing the fate of trees and forests in the coming decades. Tree water potential is a robust and direct indicator of tree water status and is preferably used to track how trees, forests and vegetation in general respond to changes in climate and drought. In this issue of Tree Physiology, Dietrich et al. (2018) predict the daily canopy water potential of mature temperate trees from tree water deficit derived from stem d...

Sustaining participation in multisector health care alliances: The role of personal and stakeholder group influence.

Cross-sectoral collaborative organizations (e.g., alliances, coalitions) bring together members from different industry sectors to ameliorate multifaceted problems in local communities. The ability to leverage the diverse knowledge and skills of these members is predicated on their sustained participation, which research has shown to be a significant challenge.

Swimming activity in zebrafish larvae exposed to veterinary antiparasitic pharmaceuticals.

Veterinary antiparasitic pharmaceuticals have been detected in surface waters and several of these pharmaceuticals act on the nervous system on the target organisms implying that neurological effects also might be of concern in non-target animals such as fish. We tested if exposure to antiparasitic pharmaceuticals affect swimming activity in 6 days old zebrafish larvae. The results revealed that most pharmaceuticals did not cause any effects in swimming activity. However, larvae exposed to 0.58 mg/L doram...

Effectiveness of National Pricing Policies for Patent-Protected Pharmaceuticals in the OECD: A Systematic Literature Review.

The aim of this review is to assess the current state of empirical research regarding the effectiveness of national pricing regulations of the patent-protected market for prescription pharmaceuticals. Effectiveness is understood to be the capacity of policies to have a desired impact on outcomes, such as health status, patient access, healthcare expenditure, and research investments, among others.

Spruce and beech as local determinants of forest fungal community structure in litter, humus and mineral soil.

Beech forests reaches its native distribution limit in SE Norway, but is expected to expand substantially northwards due to climate warming. This may potentially result in a fundamental transformation of contemporary Northern European forests, with tentative effects on the associated belowground fungi. Fungal communities mediate vital ecosystem processes such as ecosystem productivity and carbon sequestration in boreal forests. To investigate how soil fungi is affected by the vegetation transition from spru...

Chemical profile and pharmacological effects of the resin and essential oil from Bursera slechtendalii: A medicinal "copal tree" of southern Mexico.

This study reports on the volatile profile and pharmacological activities of the essential oil and resin from Bursera slechtendalii, an aromatic medicinal tree commercialized in southern Mexico. The essential oil contained 25 volatiles including p-cymen-8-ol (25.4-35.7%), n-hexyl hexanoate (6.8-17.6%) and n-octyl hexanoate (7.6-14.8%), whereas the crystallized resin contained 14 volatiles, including n-octyl acetate (29.6-34.2%), limonene (15.8-18.7%) and n-octyl butyrate (12.6-17-6%). The inhalation of vapo...

Repeated summer drought delays sugar export from the leaf and impairs phloem transport in mature beech.

Phloem sustains maintenance and growth processes through transport of sugars from source to sink organs. Under low water availability, tree functioning is impaired, i.e., growth/photosynthesis decline and phloem transport may be hindered. In a 3-year throughfall exclusion (TE) experiment on mature European beech (Fagus sylvatica L.) we conducted 13CO2 branch labeling to investigate translocation of recently fixed photoassimilates under experimental drought over 2 years (2015 and 2016). We hypothesized (H1) ...

Cardiovascular Risk Profile of Transgender Women with HIV: A U.S. Healthcare Database Study.

We sought to characterize the cardiovascular disease (CVD) risk factor profile of transgender women with HIV identified through a U.S. healthcare database. Compared with age- and race-matched cisgender men with HIV, transgender women with HIV had an increased prevalence of anemia and lower absolute hemoglobin levels. HIV control was sub-optimal and prevalence of HCV co-infection was high among transgender women. Further study of non-traditional CVD risk factors/immune activation among transgender women with...

Tree-Based Unrooted Nonbinary Phylogenetic Networks.

Phylogenetic networks are a generalisation of phylogenetic trees that allow for more complex evolutionary histories that include hybridisation-like processes. It is of considerable interest whether a network can be considered 'tree-like' or not, which leads to the introduction of tree-based networks in the rooted, binary context. Tree-based networks are those networks which can be constructed by adding additional edges into a phylogenetic tree, called the base tree. Previous extensions have considered exten...

Chiral pharmaceuticals: Environment sources, potential human health impacts, remediation technologies and future perspective.

Chiral pharmaceuticals (CPs), including non-steroid anti-inflammatory drugs (NSAIDs), β-blockers and some herbicide and pesticides, are widely used in aquaculture, clinical treatment and many other fields. However, people are increasingly concerned about such ubiquitous pollutants, which can frequently be detected in contaminated soil and water. In large part, the significant sources of chiral pharmaceuticals stem from industrial processes, such as the direct discharge of untreated or incompletely treated ...

The Second Society for Simulation in Healthcare Research Summit: Beyond our Boundaries.

In this article, we report on the Second Society for Simulation in Healthcare Research Summit held in 2017. This meeting succeeded the First Research Summit from 2011 with the goal of advancing the scope of healthcare simulation research. During the one and a half day summit, some of the world's leading experts in simulation, healthcare, and simulation in healthcare convened to discuss ideas about what research goals would be most beneficial to the healthcare simulation community, and what could be done to ...

Comparison of Decision Tree and Logistic Regression Models for Utilization in Sexual Assault Kit Processing.

To combat the influx of sexual assault kits (SAKs) that need to be tested, an exploration of data from Ohio's SAK Testing Initiative was carried out to identify variables that impact whether a SAK contains a probative DNA profile that is eligible for the Combined DNA Index System (CODIS) database. A validation study was completed to confirm the existence of variable relationships from the initial examination of data; new and modified statistical models were introduced to improve the predictive accuracy to d...

Culled banana resistant starch-soy protein isolate conjugate based emulsion enriched with astaxanthin to enhance its stability.

The conjugates of biomacromolecules such as protein and polysaccharides have potential to stabilize the emulsion system and encapsulate valuable bioactive compounds for biofortification in food systems. In this study, native banana starch (NBS) was isolated from green culled banana and modified into resistant starch (type III) by lintnerization followed by autoclaving-cooling process, resulting in lintnerized-autoclaved banana starch (LABS). Soy protein isolate (SPI) was used for developing the polysacchari...

Letter--Incorporating Real-World Evidence and Patient Value Criteria into Value-Based Frameworks for Relapsed/Refractory Multiple Myeloma.

Orlowski has received research funding from Amgen, BioTheryX, Bristol-Myers Squibb, Celgene Corporation, and Takeda Pharmaceuticals; honoraria from Amgen, Bristol-Myers Squibb, Celgene Corporation, Janssen, Millennium Pharmaceuticals, and Onyx Pharmaceuticals; and is a member of advisory boards for Amgen, Bristol-Myers Squibb, Celgene Corporation, Incyte, Kite, Legend Biotech, Sanofi-Aventis, and Takeda Pharmaceuticals.

Development of a decision tree for mitochondrial dysfunction: Uncoupling of oxidative phosphorylation.

Mitochondrial dysfunction is the result of a number of process including the uncoupling of oxidative phosphorylation. This study outlines the development of a decision tree-based profiling scheme capable of assigning chemicals to one of six confidence-based categories. The decision tree is based on a set of structural alerts and physico-chemical boundaries identified from a detailed study of the literature. The physico-chemical boundaries define a chemical relationship with both log P and pKa. The study als...

Stress Among Healthcare Professionals Calls Out for Attention.

Trends in interorganizational transactions in personalized medicine development.

Personalized medicine is an innovative concept that allows patients with a validated companion diagnosis (CoDx) to receive treatment using the most suitable drug. Currently, a major movement in the pharmaceutical industry involves the integrated use of multiple resources from external sources. To ascertain preferable interorganizational collaborations and their suitable exits, we compared the related transactions in personalized and nonpersonalized cancer drugs. We found that there were significantly more o...

PRACTITIONER APPLICATION: Innovative Leadership Initiatives to Reduce the Cost of Healthcare.


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