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PubMed Journals Articles About "Bioverativ Taps Manufacturer Steps Biogen Shadow" RSS

15:48 EDT 14th August 2018 | BioPortfolio

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Showing "Bioverativ taps manufacturer steps Biogen shadow" PubMed Articles 1–25 of 1,600+

In utero Partial Exchange Transfusion Combined with in utero Blood Transfusion for Prenatal Management of Twin Anemia-Polycythemia Sequence.

Monochorionic twin pregnancies are at risk of unique complications due to placental sharing and vascular connections between placental territories assigned for each twin. Twin anemia-polycythemia sequence (TAPS) is an infrequent but potentially dangerous complication of abnormal placental vascular connections. TAPS occurs due to very-small-caliber (< 1 mm) abnormal placental vascular connections which lead to chronic anemia in the donor twin and polycythemia in the recipient twin. TAPS may occur spontaneous...


Carbon Emission Reduction with Capital Constraint under Greening Financing and Cost Sharing Contract.

Motivated by the industrial practices, this work explores the carbon emission reductions for the manufacturer, while taking into account the capital constraint and the cap-and-trade regulation. To alleviate the capital constraint, two contracts are analyzed: greening financing and cost sharing. We use the Stackelberg game to model four cases as follows: (1) in Case A1, the manufacturer has no greening financing and no cost sharing; (2) in Case A2, the manufacturer has greening financing, but no cost sharing...

Egocentric Temporal Action Proposals.

We present an approach to localize generic actions in egocentric videos, called temporal action proposals (TAPs), for accelerating the action recognition step. An egocentric TAP refers to a sequence of frames that may contain a generic action performed by the wearer of a head-mounted camera, e.g., taking a knife, spreading jam, pouring milk, or cutting carrots. Inspired by object proposals, this paper aims at generating a small number of TAPs, thereby replacing the popular sliding window strategy, for local...


Retailer Stackelberg game in a supply chain with pricing and service decisions and simple price discount contract.

This paper studies the Retailer Stackelberg game in a supply chain consisting of two manufacturers and one retailer where they compete simultaneously under three factors including price, service and simple price discount contract. It is assumed that the second manufacturer provides service directly to his customers, and the retailer provides service for the first product's customers, while the retailer buys the first product under price discount from the first manufacturer. The analysis of the optimal equil...

Quantitative shadow compensated optical coherence tomography of choroidal vasculature.

Conventionally rendered optical coherence tomography (OCT) images of the posterior segment contain shadows which influence the visualization of deep structures such as the choroid. The purpose of this study was to determine whether OCT shadow compensation (SC) alters the appearance of the choroid and the apparent choroidal vascularity index (CVI), an OCT-derived estimated ratio of luminal to total choroidal volume. All scans were shadow compensated using a previously published algorithm, binarized using a n...

Factor Structure and Psychometric Properties of the Thoughts About Psychotherapy Survey in a Parent Sample.

Researchers have noted that treatment fearfulness (e.g., embarrassment or negative attitudes) causes individuals to avoid seeking therapy. The purpose of this study was to examine the psychometric properties of the Thoughts About Psychotherapy Survey (TAPS; Kushner and Sher in Prof Psychol Res Prac 20(4):251-257, 1989) in a sample of parents. This study also examined differences in therapy fears among parents with and without a history of using mental health services. Using a sample of 138 parents (87% fema...

Plasmonic and SERS Performances of Compound Nanohole Arrays Fabricated by Shadow Sphere Lithography.

Several plasmonic compound nanohole arrays (CNAs), such as triangular nanoholes and fan-like nanoholes with multiple nanotips and nanogaps, are designed by a simple and efficient shadow sphere lithography (SSL) technique by tuning the sphere mask size, the deposition and azimuthal angles, substrate temperature TS, and the number of deposition steps N. Compared with conventional circular nanohole arrays (CCNAs), the CNAs show more hot spots and exhibit new transmission speaks. Systematic FDTD calculations in...

Convolutional Neural Network-Based Shadow Detection in Images Using Visible Light Camera Sensor.

Recent developments in intelligence surveillance camera systems have enabled more research on the detection, tracking, and recognition of humans. Such systems typically use visible light cameras and images, in which shadows make it difficult to detect and recognize the exact human area. Near-infrared (NIR) light cameras and thermal cameras are used to mitigate this problem. However, such instruments require a separate NIR illuminator, or are prohibitively expensive. Existing research on shadow detection in ...

Who is my Jung? A personal and symbolic history.

Identifying the reality of Jung in my life requires first of all a historical examination. How Jung first came into my life through my reading a book by P.W.Martin, Experiment in Depth, stands as a metaphor for the conscious unravelling of psychological development. His further appearance in a sequence of dreams demonstrated the significance of both the instinctual and the numinous in Jung's life and in my personal individuation. Finally, through a consideration of light and shadow, particularly in two phot...

Four Key Steps Control Glycolytic Flux in Mammalian Cells.

Altered glycolysis is a hallmark of diseases including diabetes and cancer. Despite intensive study of the contributions of individual glycolytic enzymes, systems-level analyses of flux control through glycolysis remain limited. Here, we overexpress in two mammalian cell lines the individual enzymes catalyzing each of the 12 steps linking extracellular glucose to excreted lactate, and find substantial flux control at four steps: glucose import, hexokinase, phosphofructokinase, and lactate export (and not a...

Managing Risk Aversion for Low-Carbon Supply Chains with Emission Abatement Outsourcing.

Reducing carbon emissions, including emission abatement outsourcing at the supply-chain level, is becoming a significant but challenging problem in practice. Confronting this challenge, we therefore break down the practice to focus on a low-carbon supply chain consisting of one supplier, one manufacturer and one third-party emission-reducing contractor. The contractor offers a carbon reduction service to the manufacturer. In view of the increasing proportion of Greenhouse Gases (GHG) emissions and absence o...

The effects of biological buffers TRIS, TAPS, TES on the stability of lysozyme.

To explore the mechanism of lysozyme stabilization in buffer system, we have investigated the interactions between lysozyme and the biological buffers (TRIS, TAPS, and TES) using spectroscopic techniques, including ultraviolet-visible (UV-Vis), fluorescence, thermal fluorescence, dynamic light scattering (DLS), Fourier transform infrared spectroscopy (FTIR) and circular dichroism (CD) spectroscopy. From the series of spectroscopic studies, it is found that the native structure of the protein remains intact ...

Denial: in its own shadow.

My People, 2014.

A nurse with a gravely injured family member taps a hidden network of support.

Denial: in its own shadow (a clinical response).

Chemoenzymatic Approach to Tetrodotoxin: Synthesis of Fukuyama's, Alonso's, and Sato's Advanced Intermediates.

The advanced intermediates in the syntheses of tetrodotoxin reported by Fukuyama, Alonso, and Sato were prepared. The key steps in the synthesis of the title compounds involved the toluene dioxygenase-mediated dihydroxylation of either iodobenzene or benzyl acetate. The resulting diene diols were transformed to Fukuyama's intermediate in seven steps, to Alonso's intermediate in nine steps and to Sato's intermediate in ten steps, respectively.

Significant differences between manufacturer and surgeon in the accuracy of final component size prediction with CT-based patient-specific instrumentation for total knee arthroplasty.

Patient-specific instrumentation (PSI) for total knee arthroplasty (TKA) may improve component sizing. Little has been reported about accuracy of the default plan created by the manufacturer, especially for CT-based PSI. The goal of this study was to evaluate the reliability of this plan and the impact of the surgeon's changes on the final accuracy of the guide sizes.

Higher-order Extended Lagrangian Born-Oppenheimer Molecular Dynamics for Classical Polarizable Models.

Generalized extended Lagrangian Born-Oppenheimer molecular dynamics (XLBOMD) methods provides a framework for fast iteration-free simulations of models that normally require expensive electronic ground state optimizations prior to the force evaluations at every time step. XLBOMD uses dynamically driven auxiliary degrees of freedom that fluctuate about a ground state along with an approximate 'shadow' potential for which an easily obtained, variationally optimized ground state approximates the true reference...

Electrocardiogram failure in the operating room - manufacturer's comment.

Shadow Mask Templates for Site-Selective Metal Exchange in Magnesium Porphyrin Nanorings.

Molecular templates can be used in many different ways to control the outcome of chemical reactions. Here we present a new type of template-directed synthesis. We show that templates can be used as shadow masks: the shape of the template becomes imprinted on the product because reaction only occurs at sites not masked by the template. We demonstrate this effect by using oligopyridine templates to dictate the sites of demetallation when a magnesium porphyrin nanoring is treated with acid. Magnesium centers t...

Reference intervals and diagnostic ranges for serum free κ and free λ immunoglobulin light chains vary by instrument platform: Implications for classification of patient results in a multi-center study.

Serum free light chain (FLC) immunoglobulins are key biomarkers that aid in the diagnosis, prognosis and assessment of treatment response in patients with plasma cell disorders (PCD). Here we investigated the transference of manufacturer's reported κFLC, λFLC and κ to λ FLC reference intervals (RI) and established de novo FLC RI and diagnostic ranges on four instruments at three academic medical centers. In addition, we also compared the classification of patient FLC results using manufacturer's versus ...

Quantification of vitamin D in commercial dog foods and comparison with Association of American Feed Control Officials recommendations and manufacturer-reported concentrations.

OBJECTIVE To quantify vitamin D (VitD) concentrations in commercial dog foods and compare those concentrations with Association of American Feed Control Officials (AAFCO) recommendations and manufacturer-reported concentrations. DESIGN Cross-sectional study. SAMPLE 82 commercial dog foods. PROCEDURES Samples of commercially available dog foods were obtained from owners of healthy dogs in the Guelph, ON, Canada, area and owners of dogs that were patients at the Ontario Veterinary College Health Sciences Cent...

Qualitative Exploration of the Feasibility and Acceptability of Workplace-based Microgrants to Improve Physical Activity: The 10,000 Steps Pedometer Microgrant Scheme.

Despite the benefits associated with workplace health programs, many organisations are unable to offer them due to financial constraints. To address this barrier, the existing 10,000 Steps program trialled the 10,000 Steps Pedometer Microgrant Scheme. This study assessed the feasibility and acceptability of the Microgrant Scheme.

A unified approach for the assembly of atisine- and hetidine-type diterpenoid alkaloids: Total syntheses of azitine and the proposed structure of navirine C.

A tetracyclic dinitrile was synthesized in 12 steps from cyclohex-2-en-1-one by using a chelation-triggered conjugate addition to g-hydroxy a,b-unsaturated nitrile and oxidative-dearomatization/Diels-Alder cycloaddition as the key steps. The first total synthesis of azitine (in 17 steps) was achieved through a simple reductive cyclization of this intermediate and subsequent transformations, while total synthesis of the proposed structure of navirine C (in 19 steps) was accomplished via a HAT reaction of the...

A Case of Long-Term Survival after Resection of Metachronous Metastases to the Liver and Lungs from Primary Rectal Cancer.

A 81-year-old man had undergone high anterior resection for rectalcancer in 20XX. Abdominalcomputed tomography (CT)showed an isolated shadow of 2 cm in size in the liver, 9 years after surgery for colorectal cancer. We performed liver S4 segmental resection and cholecystectomy. Histopathological examination confirmed liver metastases of rectal cancer. On examination of the liver metastasis 5 years after surgery, chest CT showed a shadow of 10mm in size in S6 of the left lung. We performed partialresection v...


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