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15:03 EDT 26th March 2019 | BioPortfolio

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Showing "Boehringer Ingelheim Corporation" PubMed Articles, all 1

Establishment of a CFD-based k a model in microtiter plates to support CHO cell culture scale-up during clone selection.

Microtiter plates are a common tool for clone selection in biopharmaceutical development. A way of visualizing and evaluating these systems and key processes parameters is the application of Computational Fluid Dynamics (CFD). CFD is a powerful tool for the modelling of hydrodynamics and mass transfer parameters. In this work, CFD was used to determine the specific surface area, the volumetric power input and the oxygen mass transfer coefficient k a for two different microtiter plates with different scales ...

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