PubMed Journals Articles About "China Dental Bone Graft Substitutes Other Biomaterials Market" RSS

20:08 EDT 24th March 2019 | BioPortfolio

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Showing "China Dental Bone Graft Substitutes Other Biomaterials Market" PubMed Articles 1–25 of 10,000+

Research on implants and osseointegration.

Osseointegration was originally defined as a direct structural and functional connection between ordered living bone and the surface of a load-carrying implant. It is now said that an implant is regarded as osseointegrated when there is no progressive relative movement between the implant and the bone with which it is in direct contact. Although the term osseointegration was initially used with reference to titanium metallic implants, the concept is currently applied to all biomaterials that have the abilit...

Horizontal ridge augmentation with guided bone regeneration using particulate xenogenic bone substitutes with or without autogenous block grafts: A randomized controlled trial.

To evaluate dimensional bone alterations following horizontal ridge augmentation using guided bone regeneration (GBR) with or without autogenous block graft (ABG) for the rehabilitation of atrophic jaws with dental implants.

Maxillary Alveolar Ridge Atrophy Reconstructed With Autogenous Bone Graft Harvested From the Proximal Ulna.

Atrophy of the alveolar ridge requires bone grafting at the implant site for rehabilitation of the masticatory function with dental implants. Despite the advances in the development of bone substitutes, autogenous bone graft remains the "criterion standard" because of its osteogenic, osteoinductive, osteoconductive potential, and non-immunogenic properties. However, harvesting of autogenous bone is not exempt from donor site morbidity. In this context, the use of autogenous bone derived from the proximal ul...

Biomineralization-Inspired Material Design for Bone Regeneration.

Synthetic substitutes of bone grafts, such as calcium phosphate-based ceramics, have shown some good clinical successes in the regeneration of large bone defects and are currently extensively used. In the past decade, the field of biomineralization has delivered important new fundamental knowledge and techniques to better understand this fascinating phenomenon. This knowledge is also applied in the field of biomaterials, with the aim of bringing the composition and structure, and hence the performance, of s...

Vertical ridge augmentation using guided bone regeneration procedure and dental pulp derived mesenchymal stem cells with simultaneous dental implant placement: A histologic study in a sheep model.

To determine the effects of bone graft and dental pulp derived mesenchymal stem cells (DPMSCs) implantation with simultaneous dental implant placement on osteointegration, newly formed bone and vertical bone height histologically and histomorphometrically in a sheep model.

Xenogeneic bone matrix immune risk assessment using GGTA1 knockout mice.

Homeotransplantation of bones for replacement therapy have been demonstrated reliably in clinical data. However, human donor bones applicable for homeotransplantation are in short supply, which facilitates the search for suitable alternatives, such as xenografts grafts. The α-Gal antigen-related immune risk of xenografts directly affects the safety and effectiveness of the biomaterials and limits their applications in the clinic. The immune risk can be prevented by depletion or breaking anti-Gal antibody p...

Comparing "intra operative" tissue engineering strategies for the repair of craniofacial bone defects.

In craniofacial reconstruction, the gold standard procedure for bone regeneration is the autologous bone graft (BG). However, this procedure requiring bone harvesting is a source of morbidity. Bone substitutes, such as biphasic-calcium-phosphate (BCP), represent an interesting alternative but are not sufficient for bone healing in hypoplastic conditions. In such conditions, osteoprogenitors are essential to provide osteoinduction. Previous studies have shown that BCP associated with total bone marrow (TBM) ...

Calcium release and physical properties of modified carbonate apatite cement as pulp capping agent in dental application.

Carbonate apatite (COAp) and silica-calcium phosphate composite (SCPC) are bone substitutes with good prospect for dental application. SCPC creates a hydroxyapatite surface layer and stimulate bone cell function while, COAp induce apatite crystal formation with good adaptation providing good seal between cement and the bone. Together, these materials will add favorable properties as a pulp capping material to stimulate mineral barrier and maintain pulp vitality. The aim of this study is to investigate modif...

Bone morphogenic protein expression and bone formation are induced by bioactive glass S53P4 scaffolds in vivo.

The two-stage induced-membrane (IM) technique is increasingly used for treatment of large bone defects. In stage one, the bone defect is filled with polymethylmethacrylate (PMMA), which induces a membrane around the implant. In stage two, PMMA is replaced with bone graft. Bioactive glasses (BAGs) are bone substitutes with bone-stimulating and angiogenic properties. We have previously shown that a certain type of BAG can also induce a foreign-body membrane similar to PMMA. The aim of this study was to evalua...

Evaluation of bone regeneration in periapical osseous defects with and without Platelet rich plasma, combined Calcium sulfate and autologous bone graft -A comparative study.

Osseous defects of the jaw occurs naturally by pathological conditions such as infections, tumors, cysts or iatrogenic causes induced during surgical treatment of preexisting periradicular bony pathologies. Management of these bone defects poses a great challenge for surgeons who are continually exploring ways to find new modalities to improvise bone substitutes.

Impaired osseointegration of dental implants associated with orthognathic surgery: Possible regional acceleratory phenomenon.

Regional acceleratory phenomenon (RAP) is demonstrated to decrease regional bone mineral density and accelerate bone turnover. Hypothesizing that RAP can negatively affect the osseointegration of biomaterials, this study aimed to investigate the possible influence of the RAP on dental implant osseointegration.

Comparison Study of Three Hydroxyapatite-Based Bone Substitutes in a Calvarial Defect Model in Rabbits.

The aim of this study was to investigate the in vivo performance, including bone regeneration and biomaterial degradation, of three hydroxyapatite-based bone substitutes at surgically created defects in the cranium of rabbits.

Recombinant Human Bone Morphogenic Protein-2 Combined With Autogenous Bone Graft for Reconstruction of Alveolar Cleft.

Recombinant human bone morphogenic proteins (rhBMPs) have been introduced for reconstruction of alveolar defects. The volume of the bone formed at the cleft region may be related to rhBMP-2 dose. Greater side effects have been reported with increased doses of rhBMP-2. The aim of the present study was to assess the bone at the cleft area using low dose of rhBMP-2 combined with autogenous bone graft for reconstruction of the alveolar cleft. Patients with unilateral cleft lip and palate between the 11 to 14 ye...

Effects of methods of hydration of a biphasic ceramic graft on bone regeneration of extraction socket defects.

alveolar volumetric changes are inherent to the healing process after tooth extraction and filling of the extraction site with biomaterials can reduce these volumetric changes and provide a more favorable environment for the future prosthetic restoration with implants. Among the biomaterials available, biphasic ceramic compounds have shown promissing clinical results, however, histological evaluation of bone tissue response to different hydration and incorporation methods are limited. The objective of this ...

NHS dentistry is falling behind in an overall growing dental market.

Dental device market prepared for Amazon growth amid safety fears.

Chitosan as a Bone Scaffold Biomaterial.

The current standard of care for bone reconstruction, whether secondary to injury, nonunion, cancer resection, or idiopathic bone loss, is autologous bone grafting. Alternatives to autograft and allograft bone substitutes currently being researched are synthetic and natural graft materials that are able to guide bone regeneration. One promising material currently being researched is chitosan, a highly versatile, naturally occurring polysaccharide, derived from the exoskeleton of arthropods that is comprised...

Impact of graft and tunnel orientation on patient-reported outcome in anterior cruciate ligament reconstruction using bone-patellar tendon-bone autografts.

The optimal positioning of anterior cruciate ligament graft is still controversially discussed. We therefore wanted to determine the tunnel-to-joint (TJA), tunnel-to-shaft (TSA), and graft-tunnel divergence angles which would provide the best outcome, determined by the KOOS (Knee Injury and Osteoarthritis Outcome Score). This study evaluated the clinical influence of graft orientation as measured with the KOOS questionnaire in patients with anterior cruciate ligament reconstruction with bone-patellar tendon...

Histopathological Evaluation of Polycaprolactone Nanocomposite Compared with Tricalcium Phosphate in Bone Healing.

In recent years, the use of bone scaffolds as bone tissue substitutes, especially the use of such as hydroxyapatite and tricalcium phosphate, has been very popular. Today, the use of modern engineering techniques and advances in nanotechnology have expanded the use of nanomaterials as bone scaffolds for bone tissue applications.

Use of Recombinant Human Bone Morphogenetic Protein-2 at the C1-2 Lateral Articulation Without Posterior Structural Bone Graft in Posterior Atlantoaxial Fusion in Adult Patients.

Posterior atlantoaxial fusion is an important armamentarium for neurosurgeons to treat several pathologies involving the craniovertebral junction. Although the potential advantages of recombinant human bone morphogenetic protein -2 (rhBMP-2) are well-documented in the lumbar spine, its indication in C1-2 fusion has not been well-characterized. In our institution, we apply rhBMP-2 to the C1-2 joint either alone or with hydroxyapatite, locally harvested autograft chips, and/or morselized allogenic bone graft ...

MFC Bone Graft for Scaphoid Nonunion, Osteonecrosis, and Failed Prior Surgery: Three Strikes But Not Necessarily Out: Commentary on an article by Nicholas Pulos, MD, et al.: "Free Vascularized Medial Femoral Condyle Bone Graft After Failed Scaphoid Nonunion Surgery".

Preservation of Dental Sockets Filled with Composite Bovine Bone. A Single-Blind Randomized Clinical Trial.

The purpose of this study was to evaluate the preservation of alveolar dimensions in human fresh extraction sockets filled with a composite bovine bone graft by means of design of single-blind randomized clinical trial. Forty participants had monoradicular teeth extracted (one teeth in each participant), and after were randomly divided into 2 groups: individuals whose fresh sockets were filled with the composite heterologous bone graft (Biomaterial Group), or with blood clot (Control Group). After extractio...

Osseous Remodeling Around Dental Implants.

Adequate bone remodeling may be a primary parameter for long term successful complication-free dental implant treatment. A 1.8mm osseous thickness around dental implants is thought to be the minimum thickness for adequate vasculature for osteocyte nutrition and function. A dental implant does not provide progenitor cells or angiogenic or osteogenic factors. Thus, the surrounding bone may need to have a 1.8mm thickness to accommodate the vasculature necessary for nutrients for appropriate remodeling. Additio...

Managing Bone Grafts for the Mandible.

Bone grafting has become an integral part of implant dentistry. To achieve a predictable long-term outcome for osseointegrated implants, a sufficient volume and quality of alveolar bone must be present at implant recipient sites. Resorption of the alveolar ridge and postsurgical or post-traumatic defects of the residual alveolar bone can prevent ideal placement of a dental implant. Thus, in many cases, alveolar bone grafting is the real challenge in implant reconstruction. This article will discuss the vari...

Synergistic effect of hyperbaric oxygen therapy with PTH 1-34 on calvarial bone graft in irradiated rat.

To determine the synergistic effect of parathyroid hormone (PTH) [1-34] in combination with hyperbaric oxygen (HBO) on bone graft in a rat calvarial bone defect model under impaired osteogenic conditions.

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