PubMed Journals Articles About "Clinical Performance Of A Chlorhexidine Antimicrobial Dressing" RSS

04:11 EST 19th February 2019 | BioPortfolio

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Showing "Clinical Performance Chlorhexidine Antimicrobial Dressing" PubMed Articles 1–25 of 40,000+

Clinical and in vitro performance of an antibiofilm Hydrofiber wound dressing.

To compare the clinical and in vitro performance of a next-generation antibiofilm silver dressing (NGAD) with an established antimicrobial dressing technology that was developed before the recognition of wound biofilm as a clinical challenge.

In Vitro Antimicrobial Effect of Bioadhesive Oral Membrane with Chlorhexidine Gel.

This study aimed to evaluate in vitro the antimicrobial effect of a bioadhesive chitosan-based oral membrane with chlorhexidine for local treatment of infections in the oral tissues. Five oral membranes of different compositions were tested: 5% chitosan (G1); 5% chitosan ± 0.2% chlorhexidine (G2), 5% chitosan ± 0.6% chlorhexidine (G3), 5% chitosan ± 1.0% chlorhexidine (G4), and 5% chitosan ± 2.0% chlorhexidine (G5). Also, five gel types were tested according to the following compositions: 5% chitosan ge...

Antimicrobial assessment of a chitosan microfibre dressing: a natural antimicrobial.

Chitosan is a natural biopolymer and is the main structural component of the cuticles of crustaceans, insects and molluscs and the cell walls of certain fungi. It is abundant in nature and is naturally antimicrobial. A natural fibre has been created with chitosan and is being used as a wound dressing, namely Kytocel. It is an absorbent fibre dressing that is claimed to be biodegradable and biocompatible. This study was undertaken to assess the antimicrobial properties of the microfibre wound dressing using ...

Bioelectric Silver-Zinc Dressing Equally Effective to Chlorhexidine in Reducing Skin Bacterial Load in Healthy Volunteers.

The aim of the present study was to evaluate and compare the effectiveness of the silver-zinc bioelectric dressing as compared with skin preparation with 2% chlorhexidine or 4% chlorhexidine in reducing the bacterial count on the knee.

Evaluation of activity and potential for development of antimicrobial resistance to a new tinted 2% chlorhexidine gluconate / 70% isopropyl alcohol film-forming sterile preoperative skin preparation.

Chlorhexidine gluconate (CHG) is routinely used for skin antisepsis before surgery. Its activity may be affected by formulation ingredients and the presence of organic matter such as blood and proteins. This in vitro study was designed to evaluate the antimicrobial activity of a new CHG skin prep containing a film-forming copolymer, and detect its potential for development of resistance and the potential for cross-resistance to antibiotics after CHG exposure.

Tolerance of MRSA ST239-TW to chlorhexidine-based decolonization; evidence for keratinocyte invasion as a mechanism of biocide evasion.

INFORMATION: on genetic determinants of chlorhexidine tolerance (qacA carriage and MIC) in vitro is available, although evidence of the clinical impact and mechanisms remain poorly understood. We investigated why, following chlorhexidine intervention, prevalent epidemic MRSA ST22 and ST36 clones declined at an ICU, whilst an ST239-TW clone did not. The chlorhexidine tolerant ST239-TW phenotypes were assessed for their protein binding, cell adhesion and intracellular uptake potential.

Treatment of partial-thickness burns with a tulle-gras dressing and a hydrophilic polyurethane membrane: a comparative study.

The purpose of this revisited study was to compare the clinical efficacy and long-term scar evaluation of a hydrophilic polyurethane membrane (HPM), Omiderm (Omikron Scientific Ltd., Rehovot, Israel) and an antimicrobial tulle-gras dressing (TGD), Bactigras (Smith & Nephew) in the management of partial-thickness burns.

Preclinical Evaluation and Clinical Trial of Chlorhexidine Polymer Scaffold for Vital Pulp Therapy.

To evaluate the preclinical effectiveness and clinical efficacy of chlorhexidine polymer scaffold for vital pulp therapy.

Could being chlorhexidine an adequate positive control to antimicrobial photodynamic therapy in in vitro studies?

Chlorhexidine digluconate (CHX) is commonly applied as positive control of new antimicrobials, because it is considered the gold-standard for chemical plaque control. In this sense, the aim of this study was to compare the effect of treatments with curcumin-mediated aPDT and CHX in relation to the viability of specific microorganism groups in two distinct times (immediately and 24 h later).

Does chlorhexidine work as a preventive treatment for dry socket?

The literature shows dry socket to occur in approximately 25% of cases following the extraction of mandibular third molars. The most frequently used preventive medication, both in the literature and in practice, is chlorhexidine. This medication is used orally by the patient for a few days following extraction, as a rinse for a few minutes each day, or as a gel once. Two systematic reviews of the literature and meta-analyses of dozens of randomised clinical studies show that with chlorhexidine, the ri...

Use of a gelling fibre dressing in complex surgical or chronic wounds: a case series.

To evaluate the safety and performance of a gelling fibre dressing, with respect to wound exudate management, maceration and periwound skin conditions.

Daily Bathing With 4% Chlorhexidine Gluconate In Intensive Care Settings: A Randomized Controlled Trial.

to investigate whether daily bathing with a soap-like solution of 4% chlorhexidine (CHG) followed by water rinsing (CHGwr) would decrease the incidence of hospital acquired infections (HAI) in intensive care settings.

Application of self-made stretch pants in patients with burn in special sites.

The change and fixation of dressing are difficult in patients with burn in special sites of perineum, buttocks, and bilateral thighs. Therefore, we designed and made stretch pants by ourselves for dressing fixation after dressing change in patients with burns in abdomen, buttocks, and bilateral thighs. The stretch pants are made by cutting and splicing elastic fabric according to perimeters of abdomen and legs. The stretch pants are used after wound dressing change, which can fix the dressing stably, accele...

Venous leg ulcers managed using polyurethane foam with a micropore dressing: two case reports.

Cases of venous leg ulcers (VLU) are expected to rise due to the rapidly ageing population in Malaysia. Central to the management of these wounds is compression therapy together with an appropriate wound dressing. Pain and discomfort during dressing changes are common in these patients. Polyurethane foam dressings with SMARTPORE technology (micropore dressing; Mundipharma) facilitate vertical absorption of exudate to reduce risks of wound and periwound area maceration. They support easy dressing removal wit...

Antimicrobial stewardship intervention for the clinical pathways improves antimicrobial prophylaxis in surgical or non-surgical invasive therapies.

The standard duration of administration of antimicrobial prophylaxis in surgery and non-surgical invasive therapy was shortened according to the promotion of appropriate use. Here, we conducted an intervention to optimize antimicrobial prophylaxis by revising all relevant clinical pathways based on the most recent guidelines.

Clinical assessment of a foam dressing containing growth factor-enhancing hydrated polyurethanes.

This study assesses a novel dressing concept in venous leg ulcer (VLU) patients. It is based on boosting endogenous growth factor activities synthesised by functional granulation tissue.

Infection Control in Teeth with Apical Periodontitis Using a Triple Antibiotic Solution or Calcium Hydroxide with Chlorhexidine: A Randomized Clinical Trial.

This randomized clinical study compared the antibacterial effectiveness of treatment protocols using either a triple antibiotic solution (1 mg/mL) or calcium hydroxide/chlorhexidine paste as interappointment medication in infected canals of teeth with primary apical periodontitis.

Performance evaluation of the PANA RealTyper™ CRE Kit for detecting carbapenemase genes in gram-negative bacilli.

The spread of carbapenemase-producing organisms (CPOs) has been continuously reported over the past decade. The rapid and accurate detection of carbapenemase production is essential for adequate infection control and appropriate antimicrobial treatment in clinical fields. We evaluated the performance of the newly developed PANA RealTyper™ CRE Kit (PANAGENE, Daejeon, Korea) for the detection of six common carbapenemase genes (bla, bla, bla, bla, bla, and bla).

Spray Coating of Foley Urinary Catheter by Chlorhexidine-loaded Poly(ε-caprolactone) Nanospheres: Effect of Lyoprotectants, Characteristics and Antibacterial Activity Evaluation.

In this study, chlorhexidine-loaded poly(ε-caprolactone) nanospheres (CHX-NS) were prepared and successfully coated on the urinary catheters. Properties of CHX-NS were evaluated including drug loading content and the nanosphere size. Effects of different lyoprotectants for long-term storage of CHX-NS were also investigated. In vitro release study and antibacterial activity were also conducted using 20 cycles coated-urinary catheters. Results showed that the high-pressure emulsification-solvent evaporation ...

Tracking of the degradation process of chlorhexidine digluconate and ethylenediaminetetraacetic acid in the presence of hyper-pure chlorine dioxide in endodontic disinfection.

Accurate knowledge of the safety of the combined use of hyper-pure chlorine dioxide (ClO, Solumium) with different endodontic agents is not known. The objective was to investigate the possible interactions between hyper-pure ClO and Chlorhexidine digluconate (CHX) as well as hyper-pure ClO and ethylenediaminetetraacetic acid (EDTA) in vitro. High-performance liquid chromatography (HPLC) was used to analyse the reaction between ClO and CHX for studying the possible increase of para-chloroaniline (PCA). Nucle...

Chlorhexidine and octenidine use, qac genes carriage, and reduced antiseptic susceptibility in methicillin-resistant Staphylococcus aureus isolates from a healthcare network.

With the widespread use of antiseptics in healthcare facilities for the prevention of methicillin-resistant Staphylococcus aureus (MRSA) transmission, there are concerns for antiseptic tolerance and resistance. We sought to understand the use of chlorhexidine and octenidine, qac genes carriage and reduced antiseptic susceptibilities.

Quality Over Quantity: Standardization of Pediatric HeartWare Ventricular Assist Device Dressing Changes.

Pediatric patients are unique both in their diagnosis and clinical presentation before implantation of a ventricular assist device (VAD) and in their driveline site characteristics post-implant. There is limited evidence in scholarly literature that describes complications of pediatric VAD driveline sites or approaches by which to manage them. The Cardiac Center at The Children's Hospital of Philadelphia (CHOP) follows a standard of care for HeartWare VAD (HVAD) dressing changes in the inpatient setting wit...

The quality of studies evaluating antimicrobial stewardship interventions: a systematic review.

Antimicrobial stewardship aims to optimise antibiotic use and minimise selection of antimicrobial resistance. The methodological quality of published studies in this field is unknown.

A Self-Pumping Dressing for Draining Excessive Biofluid around Wounds.

Excessive biofluid around wounds often causes infection and hinders wound healing. However, the intrinsic hydrophilicity of the conventional dressing inevitably retains excessive biofluid at the interface between the dressing and the wound. Herein, a self-pumping dressing is reported, by electrospinning a hydrophobic nanofiber array onto a hydrophilic microfiber network, which can unidirectionally drain excessive biofluid away from wounds and finally accelerate the wound healing process. The hydrophilic mic...

IncFII plasmid carrying antimicrobial resistance genes in Shigella flexneri: Vehicle for dissemination.

Plasmids harboring antimicrobial resistance determinants in clinical strains are the significant public health concern worldwide. The present study investigated for such plasmids in clinical Shigella flexneri isolates.

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