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PubMed Journals Articles About "Determining Normal Values Of BNP Levels For The Minicare BNP IVD Assay." RSS

10:39 EDT 16th July 2019 | BioPortfolio

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Showing "Determining Normal Values Levels Minicare Assay" PubMed Articles 1–25 of 30,000+

Phosphorus retention in corn, spray dried plasma protein, soybean meal, meat and bone meal, and canola meal using a precision-fed rooster assay.

Four experiments were conducted to evaluate the precision-fed rooster assay for determining excreta phosphorus retention values for 5 feed ingredients in which roosters were precision-fed the ingredients and excreta were collected quantitatively for 48 h. The first rooster assay determined the effects of increasing P intakes on excreta P retention values for corn. This assay involved feeding either 20 g of corn or 20 g of corn supplemented with increasing amounts of KH2PO4 to provide total P intakes of 5...


Phosphorus retention in corn, spray dried plasma protein, soybean meal, meat and bone meal, and canola meal using a precision-fed rooster assay.

Four experiments were conducted to evaluate the precision-fed rooster assay for determining excreta phosphorus retention values for 5 feed ingredients in which roosters were precision-fed the ingredients and excreta were collected quantitatively for 48 h. The first rooster assay determined the effects of increasing P intakes on excreta P retention values for corn. This assay involved feeding either 20 g of corn or 20 g of corn supplemented with increasing amounts of KH2PO4 to provide total P intakes of 5...

A rare cause of subclinical hypothyroidism: macro-thyroid-stimulating hormone.

Background Subclinical hypothyroidism is a situation in which the thyroid-stimulating hormone (TSH) value exceeds the upper limit of normal, but the free triiodothyronine (T3) and thyroxine (T4) values are within the normal range. The etiology is similar to overt hypothyroidism. Case presentation An 18-year-old female patient was referred to our endocrinology clinic due to elevated TSH levels detected during a routine examination. She was clinically euthyroid and had a normal thyroid ultrasound pattern. The...


Sex differences in the association between thyroid-stimulating hormone levels and depressive symptoms among the general population with normal free T4 levels.

Overt and subclinical thyroid dysfunction has been reported to be related to depression. Thyroid diseases have been known to occur more frequently in women. However, scarce data are available on effects and sex differences of changes in thyroid-stimulating hormone (TSH) levels, with a normal range of thyroid hormones, on depression. This study aimed to investigate the association between TSH levels and depressive symptoms, according to sex, in individuals from the general population with free thyroxine (fT4...

Mathematical Relationships of Individual Stereocenter er Values to dr Values.

A mathematical relationship is derived for relating the enantiomeric ratios ( er values) of two individual stereocenters within a single chiral molecule to the diastereomeric ratio ( dr). Whereas the er (or enantiomeric excess, ee) of chiral molecules is readily determined by chiral chromatography, and dr values can be determined by chromatography or NMR, modern methods for the optical determination of er values at individual functional groups do not normally determine the er and dr of the entire molecule. ...

Normal values for sagittal spinal alignment: a study of Brazilian subjects.

The purpose of this study is to investigate the normal values of and chain of correlations between spinopelvic parameters in a Brazilian population.

Serum liver fibrosis markers discriminate significant liver inflammation in chronic hepatitis B patients with normal or near-normal alanine aminotransferase.

Chronic liver inflammation caused by chronic hepatitis B virus (CHB) infection leads to liver cirrhosis and hepatocellular carcinoma. Recently, the role of alanine aminotransferase (ALT) as a predictor of liver inflammation has been questioned. The aim of this study was to investigate the utility of noninvasive fibrosis markers including hyaluronic acid (HA), collagen type IV (CIV), N-terminal propeptide of type III procollagen (PIIINP), and laminin (LN) in identifying significant liver inflammation in pati...

Normal values and test-retest variability of stimulated-echo diffusion tensor imaging and fat fraction measurements in the muscle.

To assess the test-retest variability of both diffusion parameters and fat fraction (FF) estimates in normal muscle, and to assess differences in normal values between muscles in the thigh.

Normal values for tissue velocity and strain rate imaging parameters of left and right atrial myocardium in normal subjects.

To determine normal values for tissue velocity imaging (TVI) and strain rate imaging (SRI) in the left atrium (LA) and right atrium (RA) in normal subjects.

Clinical outcomes of patients with active rheumatoid arthritis with normal acute phase reactant values.

Despite high clinical disease activity, some patients with active rheumatoid arthritis (RA) have normal acute phase reactant (APR) values. This study aimed to determine the clinical outcomes of active RA patients with normal APR values.

Levels of cortisol and neurotrophic factor brain-derived in Parkinson's disease.

The aim of this study was to evaluate salivary cortisol and plasma brain-derived neurotrophic factor (BDNF) in people with PD, to compare them with healthy controls and to associate them with levels of anxiety and depression. For this, 18 people with PD and 17 controls were recruited. The stage of the disease was determined by Hoehn and Yahr Disability Scale (H&Y), biomarkers levels were determined by enzyme-linked immunosorbent assay (ELISA) and anxiety and depression levels were assessed by the Hamilton A...

Determining of cytokine levels in the urine in clinical practice.

The paper presents data on the study of the content of cytokines (IL-1β, RAIL-1β, IL-2, IL-4, IL-10, IL-17A, TNF-, IFN-γ) in the morning urine using enzyme immunoassay in healthy individuals (n = 20) and in patients with acute glomerulonephritis (n = 93). The determination of cytokine levels in patients was carried out in the debut of the disease and 12 months after the onset of the disease. The obtained indicators of cytokine content in the urine are presented as absolute values in pg/ml and creatinine-...

A digital data interpretation method for hemagglutination inhibition assay by using a plate reader.

Hemagglutination inhibition (HAI) assay is a simple method quantifying relative binding activities of glycan-lectin interactions. Currently, interpretation of HAI data remains a manual task depending on visual observation. In this study we developed a digital data reading method for HAI assay by using the area scanning function of a microplate reader. This was based on galectin-3-induced hemagglutination inhibition assay. OD values showed a four-parameter logistic correlation with concentrations of galectin...

Optimization and validation of a method to identify skin sensitization hazards using IL-1 α and IL-6 secretion from HaCaT.

Although many methods to assess sensitization have been investigated to replace animal testing, it is still imperative to develop an in vitro method to minimize the use of animals and to classify sensitizers. Recently, an assay using the human keratinocyte cell line (HaCaT) was developed as an alternative method. Our aim was to optimize this method and validate its ability to assess sensitization. The highest dose that resulted in 75% cell viability was determined for each test substance. Then, serial dilut...

Analytical validation of a highly sensitive, multiplexed chronic myeloid leukemia monitoring system targeting BCR-ABL1 RNA.

This study describes the analytical performance of the QuantideX qPCR BCR-ABL IS Kit, the first Federal Drug Administration-cleared assay designed to monitor BCR-ABL1 fusion transcripts isolated from peripheral blood specimens from patients with chronic myeloid leukemia. This multiplex RT-qPCR assay amplifies both e13a2 and e14a2 major BCR-ABL1 transcripts and the reference target ABL1. The test results are provided in international scale (IS) values by incorporating armored RNA-based calibrators that have ...

Expected total thyroxine (TT4) concentrations and outlier values in 531,765 cats in the United States (2014-2015).

Levels exceeding the standard reference interval (RI) for total thyroxine (TT4) concentrations are diagnostic for hyperthyroidism, however some hyperthyroid cats have TT4 values within the RI. Determining outlier TT4 concentrations should aid practitioners in identification of hyperthyroidism. The objective of this study was to determine the expected distribution of TT4 concentration using a large population of cats (531,765) of unknown health status to identify unexpected TT4 concentrations (outlier), and ...

Alterations in folate-dependent one-carbon metabolism as colon cell transition from normal to cancerous.

Folate-dependent one-carbon cycle metabolism (FOCM) plays a critical role in maintaining genomic stability through regulating DNA biosynthesis, repair and methylation. Folate metabolites as well as other metabolites in the FOCM are hypothesized to be altered when cells transition from normal to cancerous state. Using cells at different stages in their development into colorectal cancer, the FOCM metabolites were profiled as an effort to phenotype the cells, and the metabolite levels were compared to the exp...

Normal Values of Renal Function measured with 99mTechnetium Mercaptoacetyltriglycine SPECT in Mice with Respect to Age, Sex and Circadian Rhythm.

The aim of this study is to present normal values for technetium mercaptoacetyltriglycine renal uptake kinetics as a function of age, sex and circadian rhythm in mice using multi-pinhole SPECT.

Cardiac Magnetic Resonance Normal Reference Values of Biventricular Size and Function in Male Athlete's Heart.

The aim of this meta-analysis was to derive normal reference values of biventricular size and function estimated by cardiac magnetic resonance (CMR) in competitive athletes.

Upregulation of Fibroblast Growth Factor 19 Is Associated with the Initiation of Colorectal Adenoma.

Fibroblast growth factor 19 (FGF19) promotes tumor growth in various types of cancer, but its function has not been investigated in the context of colorectal adenoma. Here, we report that FGF19 expression was greater in colorectal adenoma than in normal tissues, as measured by an enzyme-linked immunosorbent assay, quantitative reverse-transcription PCR and immunohistochemistry. FGF19 expression was also elevated in a subset of human colon cancer cell lines. Moreover, FGF receptor 4 (FGFR4), the cognate rece...

Serum vascular endothelial growth factor-D as a diagnostic and therapeutic biomarker for lymphangioleiomyomatosis.

In lymphangioleiomyomatosis (LAM), tuberous sclerosis gene mutations activate the mechanistic target of the rapamycin pathway, resulting in vascular endothelial growth factor-D (VEGF-D) overproduction. While the utility of serum VEGF-D testing for the diagnosis of LAM is outlined in ATS/JRS LAM Guidelines, the assay has not been fully validated for Asian populations. Our aims were to validate serum VEGF-D testing in Japan, by directly comparing measurements in Japan and the U.S., determining the diagnostic ...

Normal Atlanto-Occipital Interval In Adults Of South-East Nigeria: An evaluation of the effect of age, gender and race.

Imaging of the craniocervical junction (CCJ) following trauma is crucial for injury detection and description. Of all the anatomical measurements of the CCJ, AOI normal value is not yet well-established in adults. The aim is to determine the normal values of AOI of Nigerians aged between 21 and 60 years, using MDCT and to determine racial, age, and sex differences.

A novel LC-MS/MS assay for vitamin B, B and B determination in dried blood spots and its application in children.

Thiamin, riboflavin and pyridoxal phosphate (PLP) concentrations are useful indices for evaluating vitamin B, B and B status. Several HPLC assays have been developed for determining thiamin, riboflavin and PLP in biological matrix. However, no existing LC-MS/MS methods can be used to quantify thiamin, riboflavin and PLP in dried blood spots (DBSs), which are often used as a sampling/storage vessel for blood from infants and children. This study evaluated the validity, reliability and stability of an LC-MS/M...

Lack of choline elevation on proton magnetic resonance spectroscopy in grade I-III gliomas.

Elevated levels of choline are generally emphasized as marker of increased cellularity and cell membrane turnover in gliomas. In this study, we investigated the incidence rate of lack of choline/creatine and choline/water elevation in a population of grade I-III gliomas. A cohort of 41 patients with histopathologically confirmed gliomas underwent multi-voxel proton magnetic resonance spectroscopy on a 3 T magnetic resonance system prior to treatment. Peak areas for choline and myoinositol were measured fr...

A Highly Sensitive Sandwich ELISA to Detect CSF Progranulin: A Potential Biomarker for CNS Disorders.

Progranulin (PGRN) plays critical roles in inflammation, tumorigenesis, and neurodegeneration. PGRN levels in blood and cerebrospinal fluid (CSF) are being increasingly investigated as potential biomarkers for these disorders. However, the value of CSF PGRN as a biomarker has been limited because currently available commercial enzyme-linked immunosorbent assay (ELISA) kits have suboptimal sensitivity for detecting CSF PGRN. In this study, pairs of monoclonal antibodies (MAbs) were first screened from eleven...


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