PubMed Journals Articles About "District Court Upholds Patent Gilenya" RSS

03:43 EDT 24th September 2018 | BioPortfolio

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Showing "District court upholds patent Gilenya" PubMed Articles 1–25 of 601

Supreme Court ruling on the withdrawal of life-sustaining nutrition.

Richard Griffith, Senior Lecturer in Health Law at Swansea University, considers the Supreme Court's decision on the need to bring cases concerning the withdrawing of clinically assisted nutrition to court.

Patent term restoration for top-selling drugs in the USA.

Patents temporarily protect brand-name drugs from generic competition, but some of the 20-year patent term is used up before marketing approval. To compensate for patent life lost to clinical testing and regulatory review, current law provides patent term restoration (PTR) of up to 5 years. Examining 170 top-selling drugs approved between 2000 and 2012, we found that 49% (83 drugs) received a PTR extension (median extension: 2.75 years) yielding a median total exclusivity period of 13.75 years, compared wit...

Heart rate and pulmonary oxygen uptake response in professional badminton players: comparison between on-court game simulation and laboratory exercise testing.

Badminton is characterized by bouts of high intensity interspersed by short recovery periods. Aerobic assessment via indirect calorimetry is impractical on court because of the encumbrance of portable metabolic devices. When the relationship between heart rate (HR) and pulmonary oxygen uptake [Formula: see text] [Formula: see text] is linear, HR monitoring can provide an indirect estimation of metabolic demands on court. However, owing to the intermittent nature of badminton, the [Formula: see text] relatio...

Indian pharmaceutical patent prosecution: The changing role of Section 3(d).

India, like many developing countries, only recently began to grant pharmaceutical product patents. Indian patent law includes a provision, Section 3(d), which tries to limit grant of "secondary" pharmaceutical patents, i.e. patents on new forms of existing molecules and drugs. Previous research suggests the provision was rarely used against secondary applications in the years immediately following its enactment, and where it was, was redundant to other aspects of the patent law, raising concerns that 3(d) ...

Do patents of academic funded researchers enjoy a longer life? A study of patent renewal decisions.

This paper assesses the extent to which patent renewal data is associated with government funding in a university context by focusing on the relationship between the funded patentees and renewal decisions of their patents. The aim of this paper is to show whether receiving funding from government contributes to high-value patents as measured by the patent renewal decisions made by their owners. Our observations of academic nanotechnology patents in Canada discovered a positive relationship between funded re...

Characteristics and Outcomes of People With Intellectual and Developmental Disabilities Participating in a Mental Health Court.

This study compares characteristics and outcomes of 70 defendants with and 1,122 without intellectual and developmental disabilities (IDD) participating in a mental health court. Demographic and clinical characteristics differed, but criminal justice or program characteristics did not. Age, race, marital status, living situation, court location, health insurance status, and likelihood of mental illness or substance abuse diagnosis differed between the two groups. When controlling for other factors, a diagno...

Work and health: The constitutional court and the protection of constitutional rights in work-related accidents and illnesses.

To describe the way in which the Constitutional Court of Colombia has interpreted the use of the writ for the protection of constitutional rights in work-related illnesses. The paper explains in which cases the court has defended the use of this action and the key judicial precedents on the subject.

Exploring mental health and substance use treatment needs of commercially sexually exploited youth participating in a specialty juvenile court.

The study sought to: 1) describe the mental health and substance use profiles among participants of a specialty trafficking court program (the Succeed Though Achievement and Resilience Court); 2) describe youths' mental health and substance use treatment prior to participating in the program; and 3) examine whether abuse influences report of mental health problems and/or substance use. Retrospective case review of court files was performed on commercially sexually exploited youth who volunteered to particip...

Accelerometry-Derived Relative Exercise Intensities in Elite Women's Basketball.

This study assessed accelerometry-derived relative exercise intensity during elite women's basketball match play. The influence of player position/role and match period on relative exercise intensities was evaluated. Ten basketballers wore accelerometers during a Yo-Yo intermittent recovery test (Yo-Yo-IR1) and 18 competitive matches. Relative exercise intensity was quantified using predicted oxygen consumption reserve determined using correlations from Yo-Yo-IR1. Total time, bout frequency and bout duratio...

The influence of four or more patent lumbar arteries on persistent type II endoleak and sac expansion after EVAR.

This study aimed to review our clinical results and determine how preoperative patent lumbar arteries (LAs) influence the occurrence of type II endoleaks or aneurysm sac enlargement after endovascular aneurysm repair (EVAR), and to identify the preoperative computed tomography findings of persistent type II endoleaks from patent LAs that indicate the need for preventive procedures during EVAR.

Basic newborn resuscitation guidelines for healthcare providers in Maragua District Hospital: a best practice implementation project.

The overall aim of this project was to assess compliance with evidence-based criteria regarding newborn resuscitation among healthcare workers in the maternity units in Maragua District Hospital (a busy district hospital in Kenya).

District nursing renascent as Wales adopts safe staffing levels.

This article reflects on the history of the NHS in Wales and how this has led to its current structure. How this structure supports integrated working across primary, community and secondary care and how further integration with social care is moving forward and its direct effects on district nursing are explored. This article describes how district nursing is meeting these challenges. Support for district nurses as part of integrated multiprofessional teams is being developed to promote appropriately staff...

The epidemiology of tuberculosis in the rural Balimo region of Papua New Guinea.

Papua New Guinea (PNG) has an emerging tuberculosis (TB) epidemic which has become a national public health priority. In Western Province, there are few data about TB outside Daru and the South Fly District. This study describes the epidemiology of TB diagnosed at Balimo District Hospital (BDH) in the Middle Fly District of Western Province, PNG.

How are parental functioning and single parenthood associated with court outcomes? An analysis of child protection cases.

Impaired parental functioning and single parenthood are considered risk factors for child maltreatment and being involved in the child protection context. Past research has shown that an impaired mental functioning and being a single parent are indicators of limited parenting resources. These risk factors are likely to be considered by family judges, which might lead to more intrusive court decisions concerning parental custody. To date, court data have rarely been investigated. The present study examined p...

The influence of the UN Convention on the Rights of Persons with Disabilities on the German jurisdiction and legalisation regarding compulsory measures.

The UN Convention for the Rights of People with Disabilities (CRPD) has influenced the jurisdiction and legislation on psychiatry in Germany. It played a role in several landmark decisions of the Federal Constitutional Court and of the Federal Supreme Court, which again initiated changes of the guardianship law and of different federal mental health laws. Furthermore, the CRPD has triggered an intensive discussion within psychiatry, which has led to a more critical and cautious use of coercive measures.Howe...

Feasibility of patent and proprietary medicine vendor provision of injectable contraceptives: preliminary results from implementation science research in Oyo and Nasarawa, Nigeria.

Nigerian policymakers are debating task-shifting injectable contraceptive services to Patent and Proprietary Medicine Vendors (PPMVs).

The role of the district nurse in caring for patients with dementia.

District nurses require a vast array of skills to enable effective care delivery for patients living with a diagnosis of dementia in the community setting. Complex care needs provide challenges for the provision and delivery of district nursing services, which must be overcome to provide patientcentred care. Demographic and financial constraints hamper service delivery and the availability of services; however, district nurses are required to use their problem solving skills and tacit knowledge to deal with...

An Evidence Framework for Off-Patent Pharmaceutical Review (EFOR) for Health Technology Assessment in Emerging Markets.

This article introduces an Evidence Framework for Off-Patent Pharmaceutical Review (EFOR), which establishes value-based criteria in a template that manufacturers use to provide evidence showing how their products meet those criteria. Health authorities in emerging markets can then use the evidence presented in the EFOR to evaluate off-patent pharmaceuticals (OPPs) in a consistent, transparent, and evidence-based manner to support policy decisions, including pricing, reimbursement, formulary listing, and dr...

Closure of Patent Foramen Ovale versus Medical Therapy after Cryptogenic Stroke: Meta-Analysis of Five Randomized Controlled Trials with 3440 Patients.

We aimed to determine whether patent foramen ovale closure reduces the risk of stroke, also assessing some safety outcomes.

The first 5 years of Part 2A Orders: the use of powers from court applications to protect public health in England 2010-15.

Part 2A Orders are the legal means which allow local authorities (LAs), upon application to court, to exercise powers over persons, things or premises to protect public health.

A framework to assess management performance in district health systems: a qualitative and quantitative case study in Iran.

The aim was to design a district health management performance framework for Iran's healthcare system. The mixed-method study was conducted between September 2015 and May 2016 in Tabriz, Iran. In this study, the indicators of district health management performance were obtained by analyzing the 45 semi-structured surveys of experts in the public health system. Content validity of performance indicators which were generated in qualitative part were reviewed and confirmed based on content validity index (CVI)...

Robson 10-groups classification system to access C-section in two public hospitals of the Federal District/Brazil.

The global increase in C-section rates is real. In Brazil, these indices correspond to 58.94% in the Midwest region and 52.77% in the Federal District.

District nurses must guard against inappropriately accessing patient records.

Two NHS workers were recently disciplined after inappropriately accessing the records of the singer Ed Sheeran who had required treatment for a fractured wrist and elbow after falling from his bicycle ( Embury-Dennis 2018 ). The increasingly common use of electronic records across the NHS now allows nurses, including district nurses, to access a large archive of patient information that was much more difficult to obtain when records were manually held paper records. There have been several instances where c...

Is the Current Management of Patients Presenting With Spinal Trauma to District General Hospitals Fit for Purpose? Our Experience of Delivering a Spinal Service Using an Electronic Referral Platform in a Large District General Teaching Hospital Without Onsite Spinal Services.

A retrospective cross-sectional analysis.

Association of Placebo, Indomethacin, Ibuprofen, and Acetaminophen With Closure of Hemodynamically Significant Patent Ductus Arteriosus in Preterm Infants: A Systematic Review and Meta-analysis.

Despite increasing emphasis on conservative management of patent ductus arteriosus (PDA) in preterm infants, different pharmacotherapeutic interventions are used to treat those developing a hemodynamically significant PDA.

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