PubMed Journals Articles About "District Court Upholds Patent Gilenya" RSS

10:31 EST 16th December 2018 | BioPortfolio

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Showing "District court upholds patent Gilenya" PubMed Articles 1–25 of 615

Seeking an order to withdraw treatment from the Court of Protection.

The Court of Protection is the specialist court that makes decisions in relation to people who lack decision-making capacity. In this article, Richard Griffith considers the powers of the Court of Protection and discusses when it might be necessary for a district nurse to seek an order from the court in relation to the care or treatment of a patient.

Supreme Court ruling on the withdrawal of life-sustaining nutrition.

Richard Griffith, Senior Lecturer in Health Law at Swansea University, considers the Supreme Court's decision on the need to bring cases concerning the withdrawing of clinically assisted nutrition to court.

Patent term restoration for top-selling drugs in the USA.

Patents temporarily protect brand-name drugs from generic competition, but some of the 20-year patent term is used up before marketing approval. To compensate for patent life lost to clinical testing and regulatory review, current law provides patent term restoration (PTR) of up to 5 years. Examining 170 top-selling drugs approved between 2000 and 2012, we found that 49% (83 drugs) received a PTR extension (median extension: 2.75 years) yielding a median total exclusivity period of 13.75 years, compared wit...

Why Biologics and Biosimilars Remain So Expensive: Despite Two Wins for Biosimilars, the Supreme Court's Recent Rulings do not Solve Fundamental Barriers to Competition.

Biologics and biosimilars are medicines made from living cells that treat common and serious diseases such as cancer, diabetes, rheumatoid arthritis, and other inflammatory diseases. They are highly targeted, efficacious, and represent an increasingly important part of physicians' armamentaria in the combat against these medical conditions. Yet they are extremely expensive, costing on average $10,000-$30,000 per year and exceed $500,000 for the most expensive biologics. The advent of biosimilar drugs, or hi...

Heart rate and pulmonary oxygen uptake response in professional badminton players: comparison between on-court game simulation and laboratory exercise testing.

Badminton is characterized by bouts of high intensity interspersed by short recovery periods. Aerobic assessment via indirect calorimetry is impractical on court because of the encumbrance of portable metabolic devices. When the relationship between heart rate (HR) and pulmonary oxygen uptake [Formula: see text] [Formula: see text] is linear, HR monitoring can provide an indirect estimation of metabolic demands on court. However, owing to the intermittent nature of badminton, the [Formula: see text] relatio...

Do patents of academic funded researchers enjoy a longer life? A study of patent renewal decisions.

This paper assesses the extent to which patent renewal data is associated with government funding in a university context by focusing on the relationship between the funded patentees and renewal decisions of their patents. The aim of this paper is to show whether receiving funding from government contributes to high-value patents as measured by the patent renewal decisions made by their owners. Our observations of academic nanotechnology patents in Canada discovered a positive relationship between funded re...

Characteristics and Outcomes of People With Intellectual and Developmental Disabilities Participating in a Mental Health Court.

This study compares characteristics and outcomes of 70 defendants with and 1,122 without intellectual and developmental disabilities (IDD) participating in a mental health court. Demographic and clinical characteristics differed, but criminal justice or program characteristics did not. Age, race, marital status, living situation, court location, health insurance status, and likelihood of mental illness or substance abuse diagnosis differed between the two groups. When controlling for other factors, a diagno...

Work and health: The constitutional court and the protection of constitutional rights in work-related accidents and illnesses.

To describe the way in which the Constitutional Court of Colombia has interpreted the use of the writ for the protection of constitutional rights in work-related illnesses. The paper explains in which cases the court has defended the use of this action and the key judicial precedents on the subject.

The Reporting Items for Patent Landscapes statement.

The reporting quality of patent landscapes is inadequate. The Reporting Items for Patent Landscapes (RIPL) checklist can improve reporting quality.

Protection of patients' rights in the european court of human rights.

Introduction: Currently, there is little attention paid to studying the characteristic features of the protection of patients' rights in the European Court of Human Rights, which is the fact determining the relevance of the scientific research in this area. The aim: To define the basic rights of patients and summarize the practice of the European Court of Human Rights with regard to protection of patients' rights in order to formulate proposals as to the ways of the current legislation improvement.

The demise of drug design litigation: death by federal preemption.

For over half a century, courts and commentators have disagreed as to the standards governing liability for drug design cases. In the last several years, the United States Supreme Court decided two cases that will have a profound effect on whether drug design defect cases, in general, are federally preempted. In PLIVA v. Mensing and Mutual Pharmaceutical Co. v. Bartlett, the Court preempted product liability actions for failure to warn and design defect against the manufacturers of generic drugs that met th...


We express serious doubt and cautioning regarding Spieker and Crittenden's (2010) claim that attachment measures associated with the dynamic-maturational model of attachment and adaptation (DMM; Crittenden, 2016) can be used for court decision-making. We demonstrate, using Crittenden's and coworkers' (e.g., Spieker & Crittenden, ) own data, that such measures have (a) insufficient reliability for use in individual diagnosis and (b) cannot retrodict maltreatment with sufficient sensitivity or specificity for...

Accelerometry-Derived Relative Exercise Intensities in Elite Women's Basketball.

This study assessed accelerometry-derived relative exercise intensity during elite women's basketball match play. The influence of player position/role and match period on relative exercise intensities was evaluated. Ten basketballers wore accelerometers during a Yo-Yo intermittent recovery test (Yo-Yo-IR1) and 18 competitive matches. Relative exercise intensity was quantified using predicted oxygen consumption reserve determined using correlations from Yo-Yo-IR1. Total time, bout frequency and bout duratio...

Basic newborn resuscitation guidelines for healthcare providers in Maragua District Hospital: a best practice implementation project.

The overall aim of this project was to assess compliance with evidence-based criteria regarding newborn resuscitation among healthcare workers in the maternity units in Maragua District Hospital (a busy district hospital in Kenya).

District nursing renascent as Wales adopts safe staffing levels.

This article reflects on the history of the NHS in Wales and how this has led to its current structure. How this structure supports integrated working across primary, community and secondary care and how further integration with social care is moving forward and its direct effects on district nursing are explored. This article describes how district nursing is meeting these challenges. Support for district nurses as part of integrated multiprofessional teams is being developed to promote appropriately staff...

The epidemiology of tuberculosis in the rural Balimo region of Papua New Guinea.

Papua New Guinea (PNG) has an emerging tuberculosis (TB) epidemic which has become a national public health priority. In Western Province, there are few data about TB outside Daru and the South Fly District. This study describes the epidemiology of TB diagnosed at Balimo District Hospital (BDH) in the Middle Fly District of Western Province, PNG.

Feasibility of patent and proprietary medicine vendor provision of injectable contraceptives: preliminary results from implementation science research in Oyo and Nasarawa, Nigeria.

Nigerian policymakers are debating task-shifting injectable contraceptive services to Patent and Proprietary Medicine Vendors (PPMVs).

How are parental functioning and single parenthood associated with court outcomes? An analysis of child protection cases.

Impaired parental functioning and single parenthood are considered risk factors for child maltreatment and being involved in the child protection context. Past research has shown that an impaired mental functioning and being a single parent are indicators of limited parenting resources. These risk factors are likely to be considered by family judges, which might lead to more intrusive court decisions concerning parental custody. To date, court data have rarely been investigated. The present study examined p...

The evaluation of malpractice cases arising from aesthetic intervention in Turkey based on Supreme Court case law.

The aim of this study is to evaluate medical malpractice cases arising from aesthetic services based on the decisions of the Supreme Court.

Factors associated with home births in a selected ward in Mberengwa District, Zimbabwe.

Despite many efforts put by the Government to ensure that women give birth in health facilities under trained personnel supervision; statistics suggest that ward 2 in Mberengwa District in Zimbabwe has the highest home births. This study sought to assess factors that are associated with home births in ward 2 of Mberengwa District in Zimbabwe.

The influence of the UN Convention on the Rights of Persons with Disabilities on the German jurisdiction and legalisation regarding compulsory measures.

The UN Convention for the Rights of People with Disabilities (CRPD) has influenced the jurisdiction and legislation on psychiatry in Germany. It played a role in several landmark decisions of the Federal Constitutional Court and of the Federal Supreme Court, which again initiated changes of the guardianship law and of different federal mental health laws. Furthermore, the CRPD has triggered an intensive discussion within psychiatry, which has led to a more critical and cautious use of coercive measures.Howe...

The role of the district nurse in caring for patients with dementia.

District nurses require a vast array of skills to enable effective care delivery for patients living with a diagnosis of dementia in the community setting. Complex care needs provide challenges for the provision and delivery of district nursing services, which must be overcome to provide patientcentred care. Demographic and financial constraints hamper service delivery and the availability of services; however, district nurses are required to use their problem solving skills and tacit knowledge to deal with...

Updated Meta-analysis on the Closure of Patent Foramen Ovale in Reduction of Stroke Rates: the DEFENSE-PFO Trial Does not Change the Scenario.

We aimed to analyze whether patent foramen ovale (PFO) closure reduces the risk of stroke, assessing also some safety outcomes after the publication of a new trial.

District nurses must guard against inappropriately accessing patient records.

Two NHS workers were recently disciplined after inappropriately accessing the records of the singer Ed Sheeran who had required treatment for a fractured wrist and elbow after falling from his bicycle ( Embury-Dennis 2018 ). The increasingly common use of electronic records across the NHS now allows nurses, including district nurses, to access a large archive of patient information that was much more difficult to obtain when records were manually held paper records. There have been several instances where c...

Reduced Stroke After Transcatheter Patent Foramen Ovale Closure: A Systematic Review and Meta-analysis.

Recent randomized control trials (RCTs) have suggested benefit with transcatheter patent foramen ovale (PFO) closure plus antiplatelet therapy over medical treatment alone for secondary stroke prevention.

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