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PubMed Journals Articles About "Effect Of Probiotics On Lipid Management∨derfield=score∨derval=DESC" RSS

18:10 EDT 18th July 2019 | BioPortfolio

Effect Of Probiotics On Lipid Management∨derfield=score∨derval=DESC PubMed articles on BioPortfolio. Our PubMed references draw on over 21 million records from the medical literature. Here you can see the latest Effect Of Probiotics On Lipid Management∨derfield=score∨derval=DESC articles that have been published worldwide.

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Showing "Effect Probiotics Lipid Management derfield score derval DESC" PubMed Articles 1–25 of 35,000+

Basal Autophagy Deficiency Causes Thyroid Follicular Epithelial Cell Death in Mice.

Autophagy is a catabolic process that involves the degradation of cellular components through the lysosomal machinery, re-locating nutrients from unnecessary processes to more pivotal processes required for survival. It has been reported that systemic disruption of Atg5 or 7 gene, a component of autophagy, is lethal, and that its tissue-specific disruption causes tissue degeneration in several organs. However, the functional significance of autophagy in the thyroid glands remained unknown. Our preliminary d...


Effect of continuous positive airway pressure on inflammatory, antioxidant, and depression biomarkers in women with obstructive sleep apnea: a randomized controlled trial.

The effect of continuous positive airway pressure (CPAP) on mediators of cardiovascular disease and depression in women with obstructive sleep apnea (OSA) is unknown. We aimed to assess the effect of CPAP therapy on a variety of biomarkers of inflammation, antioxidant activity, and depression in women with OSA.

Comparison of Physician Therapeutic Inertia for Management of Patients With Multiple Sclerosis in Canada, Argentina, Chile, and Spain.

There is growing interest in understanding and addressing factors that govern the decision-making process in multiple sclerosis (MS) care. Therapeutic inertia (TI) is the failure to escalate therapy when goals are unmet. Limited data are available on the prevalence of TI and factors affecting therapeutic decisions in the management of patients with MS worldwide.


Combinational effect of angiotensin receptor blocker and folic acid therapy on uric acid and creatinine level in hyperhomocysteinemia associated hypertension.

Homocysteine [HSCH2CH2CH(NH2)COOH] (Hcy), is a sulfur-containing amino acid of 135.18 Da of molecular weight, generated during conversion of methionine to cysteine. If there is a higher accumulation of Hcy in the blood, i.e. usually above 15 µmol/L, it leads to a condition referred to as hyperhomocysteinemia. A meta-analysis of observational study suggested an elevated concentration of Hcy in blood, which is termed as the risk factors leading to ischemic heart disease (IHD) and stroke. Further experimenta...

Developmental horizons in the pre-natal development of the Greater cane rat (Thryonomys swinderianus).

The Greater cane rat (GCR, Thyronomys swinderianus) is a precocial rodent predominantly found within Africa. Economic and scientific interests have led to several research efforts towards the domestication and better understanding of the biology and development of this rodent. Despite these efforts, information on the pre-natal development of this rodent is currently lacking. This study characterises distinct developmental milestones including skin pigmentation, emergence and distributions of hairs, calvari...

Superior Mesoporosity of Lipid Free Spent Coffee Grounds Residues.

As part of the biorefinery concept for spent coffee grounds (SCG), production of activated carbon (AC) was investigated from the degreased coffee grounds (DCG) left behind after oil extraction (primarily for biodiesel). The oils were extracted via conventional solvent extraction with GC/GC-MS confirming the oil was comparable to oils produced industrially. More significantly, analysis showed the DCG AC to have a 4-fold increase in mesoporosity than the SCG AC with mesopore volumes of 0.6 and 0.15 cm3 g-1 re...

Lipid peroxidation increases hydrogen peroxide permeability leading to cell death in cancer cell lines that lack mtDNA.

Lipid peroxidation is a cause of cell and tissue injury. An important product of plasma membrane lipid peroxidation is HNE. We have established mtDNA-depleted ρ cells, which are subjected to higher oxidative stress versus their parental cells, using cervical cancer and oral squamous cell carcinoma cell lines. These ρ cells show sensitivity to H O . We investigated the effect of reactive oxygen species, especially the mechanism of H O -mediated cell death, in ρ cells. The up-regulation of HNE in the plasm...

RAC1 inhibition reverses cisplatin resistance in esophageal squamous cell carcinoma and induces downregulation of glycolytic enzymes.

Development of chemoresistance remains a major challenge in treating esophageal squamous cell carcinoma (ESCC) patients despite treatment advances. However, the role of RAC1 in chemoresistance of ESCC and the underlying mechanisms remain largely unknown. In this study, we found that higher levels of RAC1 expression were associated with poorer prognosis in ESCC patients. Enhanced RAC1 expression increased cell proliferation, migration and chemoresistance in vitro. Combination therapy using RAC1 inhibitor EHo...

A Practical Management Approach to Gastroparesis.

Gastroparesis is a syndrome characterised by delayed gastric emptying in the absence of mechanical obstruction. Symptoms can include early satiety, abdominal pain, bloating, vomiting, and regurgitation which cause significant morbidity in addition to nutritional deficits. There is a higher prevalence in diabetics and females, but the incidence in the Australian population has not been well studied. Management of gastroparesis involves investigating and correcting nutritional deficits, optimising glycaemic c...

Necessity of fundoplication and mesh in the repair of the different types of paraesophageal hernia.

The management of paraesophageal hernia (PEH) has changed significantly since the introduction of laparoscopic surgery in the 1990's. This study aims to explore the need of a Nissen fundoplication or a posterior gastropexy and the use of mesh reinforcement in the surgical repair of PEH.

Selection criteria for liver transplantation in patients with hepatocellular carcinoma. Eastern and western experiences, and perspectives for the future.

Ever since the initial description of the Milan criteria, used for selecting patients with hepatocellular carcinoma (HCC) for liver transplantation (LT), there has been a clear need to go further than solely morphological criteria. Tumours exceeding the Milan criteria, but presenting favourable biological behaviour, might still allow for comparable overall- and disease-free survivals after LT. As it is well established that the presence of microvascular invasion is a major factor that influences HCC recurre...

Adverse effects of bevacizumab in metastatic colorectal cancer : a case report and literature review.

Colorectal cancer is one of the most frequently diagnosed malignancies worldwide. One of the most important developments in the management of metastatic colorectal cancer is targeted therapy. Bevacizumab, a monoclonal antibody inhibiting VEGF induced angiogenesis, has been accepted as safe and efficient in the treatment of metastatic colorectal cancer for more than a decade. Addition of bevacizumab to fluorouracil-based chemotherapy is also associated with severe adverse events. We present a case of bevaciz...

Self-Assembled Indomethacin Dimer Nanoparticles Loaded with Doxorubicin for Combination Therapy in Resistant Breast Cancer.

An ortho ester-linked indomethacin (IND) dimer-based nanodrug delivery system was prepared to improve the therapeutic effect of doxorubicin (DOX) by reversing the multidrug resistance. The synthesized dimer (IND-OE) could form stable nanoparticles (IND-OE/DOX) loaded with DOX via single emulsion method. Compare to non-sensitive nanoparticles (IND-C12/DOX), IND-OE/DOX showed a rapid degradation behavior and accelerated drug release at mildly acidic environments. In vitro cell experiments verified that IND-OE...

Ultrafast All-Optical Modulation in 2D Hybrid Perovskites.

Two-dimensional (2D) hybrid organic-inorganic Ruddlesden-Popper perovskites (RPPs) have been recently shown to exhibit large nonlinear optical properties due to the strong excitonic effects present in their multiple quantum wells. In this work, we use nondegenerate pump-probe spectroscopy in the 600-1000 nm wavelength range to study the influence of nonlinear effects on the ultrafast dynamics of 2D RPP thin flakes. We find that, under sub-bandgap excitation, ⁓100-nm thick perovskite sheets allow up to ⁓...

Molecular Design Strategies for Color Tuning of Blue TADF Emitters.

New thermally activated delayed fluorescence (TADF) blue emitter molecules based on the known donor-acceptor-donor (D-A-D)-type TADF molecule, 2,7-bis(9,9-dimethylacridin-10-yl)-9,9-dimethylthioxanthene-,-dioxide (DDMA-TXO2), are reported. The motivation for the present investigation is via the use of rational molecular design, based on DDMA-TXO2, to elevate the organic light emitting diode (OLED) performance and obtain deeper blue color coordinates. To achieve this goal, the strength of the donor (D) unit ...

Facile Electrochemical Activity of Monoclinic Li2MnSiO4 as Potential Cathode for Li-Ion Batteries.

Synthesis of pure single phase Li2MnSiO4 is challenging because of its rich polymorphism. Here, we demonstrate our success in preparing crystalline pure, battery grade monoclinic phase Li2MnSiO4 employing temperature programmed reaction (TPR) technique. The systematic analysis of the electrochemical behavior of Li2MnSiO4 reveals the excellent battery activity in the monoclinic phase, with an initial discharge capacity of ~250 mAh g-1 associated with the reversible intercalation of more than one Li+. The ext...

Synergetic effect of facet junction and specific facet activation of ZnFe2O4 nanoparticles on photocatalytic activity improvement.

Crystal facet engineering has been proved as a versatile approach in modulating the photocatalytic activity of semiconductors. However, the facet-dependent properties and underlying mechanisms of spinel ZnFe2O4 in photocatalysis still have rarely been explored. Herein, ZnFe2O4 nanoparticles with different {001} and {111} facets exposed were successfully synthesized via a facile hydrothermal method. Facet-dependent photocatalytic degradation performance towards gaseous toluene under visible light irradiation...

Effect of Iodination on the Photophysics of the Laser Borane -BH: Generation of Efficient Photosensitizers of Oxygen.

Treatment of the laser borane -BH (compound ) with iodine in ethanol gives the monoiodinated derivative 7-I--BH (compound ) in 67% yield, or, by reaction with iodine or ICl in the presence of AlCl in dichloromethane, the diiodinated derivative 4,4'-I--BH (compound ) in 85% yield. On excitation with 360 nm light, both compounds and give strong green phosphorescent emissions (λ = 525 nm, Φ = 0.41 and λ = 545 nm, Φ = 0.71 respectively) that are quenched by dioxygen to produce O(Δ) singlet oxygen with qu...

Chemically engineered synthetic lipid vesicles for sensing and visualization of protein - bilayer interactions.

From pathogen intrusion to immune response, cell membrane plays an important role in signal transduction. Such signals are important for cellular proliferation and survival. However, measurement of these subtle signals through the lipid membrane scaffold is challenging. We present a chromatic model membrane vesicle system engineered to covalently bind with lysine residues of protein molecules for investigation of cellular interactions and signaling. We discovered that different protein molecules induced dif...

Lewis Strength Determines Specific-Ion Effects in Aqueous and Nonaqueous Solvents.

An analysis of specific-ion effects in aqueous and nonaqueous solvents using energy decomposition analysis is presented. Specific-ion effects induce or influence physicochemical phenomena in a way that is determined by the identity of the ions present, and not merely by their charge or concentration. Such effects have been known since the seminal work of Hofmeister and are often categorized according to the well-known Hofmeister series. Examples of specific-ion effects are ubiquitous throughout chemistry an...

Catalytic CO Oxidation by Gas-Phase Metal Oxide Clusters.

Oxidation of CO into CO2 is a prototypical reaction in heterogeneous catalysis and is one of the extensively studied reactions in gas phase to explore the underlying mechanisms of related catalysts. In this article, we present and discuss our recent advances in the fundamental understandings of catalytic CO oxidation by O2 mediated with heteronuclear metal oxide clusters (HMOCs) using state-of-the-art mass spectrometry and quantum chemistry calculations. The HMOCs can be considered as ideal models to provid...

Spin-Orbit Coupling-Dominated Catalytic Activity of Two-Dimensional Bismuth towards CO2 Electroreduction: Not the Thinner the Better.

Developing two-dimensional (2D) catalysts that are as thin as possible to increase the density of active sites seems to always be desirable for the pursuit of ideal catalytic performance. In this work, by taking CO2 electroreduction on 2D bismuth (Bi) as an example, we theoretically demonstrated that it is not always "the thinner the better" for 2D electrocatalysts. Due to the existence of a sizeable band gap, the Bi monolayer exhibits lower catalytic activity than thicker metallic Bi nanosheets. Remarkably...

Resonant Two-Photon Photoelectron Imaging and Intersystem Crossing from Excited Dipole-Bound States of Cold Anions.

We report the observation of a dipole-bound state (DBS) 659 cm-1 below the electron detachment threshold of cryogenically-cooled deprotonated 4,4'-biphenol anion (bPh-) and nineteen of its lowest vibrational levels. Resonant two-photon photoelectron imaging (R2P-PEI) via the vibrational levels of the DBS display a sharp peak with a constant binding energy. This observation indicates vertical detachment from the vibrational levels of the DBS to the corresponding neutral levels with the conservation of the vi...

Unsilencing of native leptin receptors (LepR) in hypothalamic SF1 neurons does not rescue obese phenotype in LepR-deficient mice.

Leptin receptor (LepR) signaling in neurons of the ventromedial nucleus of the hypothalamus (VMH), specifically those expressing steroidogenic factor-1 (SF1), have been proposed to play a key role in controlling energy balance. By crossing LepR-silenced (LepR) mice to those expressing SF1-Cre, we unsilenced native LepR specifically in the VMH and tested whether SF1 neurons in the VMH are critical mediators of leptin's effect on energy homeostasis. LepR x SF1-Cre (KO/Tg+) mice were metabolically phenotyped a...

Vulnerable Patients' Psychosocial Experiences in a Group-Based, Integrative Pain Management Program.

To use a psychosocial framework to examine the pain experiences of low-income, ethnically diverse patients before and after an Integrative Pain Management Program (IPMP). IPMP is a 12-week, multimodal pain group incorporating mindfulness, acupuncture, massage, education, movement, and health coaching. The authors conducted semistructured interviews at the beginning, end, and 3 months following completion of IPMP. Interviews were digitally recorded and transcribed and analyzed using inductive coding methods...


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