PubMed Journals Articles About "Efficacy Of Lifestyle Changes In Modifying Practical Markers Of Wellness And Aging." RSS

13:11 EST 15th November 2019 | BioPortfolio

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Showing "Efficacy Lifestyle Changes Modifying Practical Markers Wellness Aging" PubMed Articles 1–25 of 15,000+

Lifestyle predictors of successful aging: A 20-year prospective HUNT study.

Lifestyle factors predicting successful aging as a unified concept or as separate components of successful aging are important for understanding healthy aging, interventions and preventions. The main objective was to investigate the effect of midlife predictors on subsequent successful aging 20 years later.

Helping students cope with adversity: the influence of a web-based intervention on students' self-efficacy and intentions to use wellness-related resources.

To investigate the effects of an online wellness intervention on college students' self-efficacy, intentions to seek help, general resilience and whether adverse childhood experiences (ACEs) act as a moderating variable. Three-hundred and eighty-two undergraduate students. Students were assigned to two conditions: treatment or control. The treatment group participated in an online intervention designed to enhance student wellness, the control group did not. Both groups completed an online questionnaire. ...

Prevention and Treatment of Alzheimer's Disease: Biological Mechanisms of Exercise.

 Alzheimer's disease (AD) is the most common form of dementia. With an aging population and no disease modifying treatments available, AD is quickly becoming a global pandemic. A substantial body of research indicates that lifestyle behaviors contribute to the development of AD, and that it may be worthwhile to approach AD like other chronic diseases such as cardiovascular disease, in which prevention is paramount. Exercise is an important lifestyle behavior that may influence the course and pathology of A...

A Narrative Review of Lifestyle Factors Associated with Parkinson's Disease Risk and Progression.

Parkinson's disease is a complex slowly progressive neurodegenerative disorder with motor and non-motor symptoms affecting daily living. Despite effective symptomatic treatments, with various degrees of side effects, no disease-modifying therapeutic options presently exist. Symptoms progress, with an accumulating burden, reducing the quality of life and forming the impression that medications are no longer effective. Adopting positive lifestyle behaviours can empower patients, improve the quality of life, a...

Promoting cardiovascular health and wellness among African-Americans: Community participatory approach to design an innovative mobile-health intervention.

Despite improvements in mortality rates over the past several decades, cardiovascular (CV) disease remains the leading cause of death for African-Americans (AAs). Innovative approaches through mobile health (mHealth) interventions have the potential to support lifestyle change for CV disease prevention among AAs. We aimed to translate a behavioral theory-informed, evidence-based, face-to-face health education program into an mHealth lifestyle intervention for AAs. We describe the design and development of a...

Conserved aging-related signatures of senescence and inflammation in different tissues and species.

Increasing evidence indicates that chronic inflammation and senescence are the cause of many severe age-related diseases, with both biological processes highly upregulated during aging. However, until now, it has remained unknown whether specific inflammation- or senescence-related genes exist that are common between different species or tissues. These potential markers of aging could help to identify possible targets for therapeutic interventions of aging-associated afflictions and might also deepen our un...

Socioeconomic position, lifestyle habits and biomarkers of epigenetic aging: a multi-cohort analysis.

Differences in health status by socioeconomic position (SEP) tend to be more evident at older ages, suggesting the involvement of a biological mechanism responsive to the accumulation of deleterious exposures across the lifespan. DNA methylation (DNAm) has been proposed as a biomarker of biological aging that conserves memory of endogenous and exogenous stress during life.We examined the association of education level, as an indicator of SEP, and lifestyle-related variables with four biomarkers of age-depen...

Incentivizing healthy lifestyle behaviors to reduce cardiovascular risk in people with serious mental illness: An equipoise randomized controlled trial of the wellness incentives program.

Medicaid recipients with serious mental illness die 25-30 years earlier than people in the general population due to health conditions that are modifiable through lifestyle changes. Cardiovascular diseases from excess weight, smoking, and sedentary lifestyle contribute substantially to this life expectancy disparity. The current study evaluated the impact of incentives on participation in weight management programming (for overweight and obese adults) and smoking cessation treatment (for regular smokers).

Characterization of Volatile Organic Compounds as Potential Ageing-markers in Chinese Rice Wine using Multivariable Statistics.

It was always eye-catching for the 'ageing-markers' in wine, as one type of volatile organic compounds (VOCs) with a significant trend during the aging process, because their changes during the aging process suggested a close relationship between these ageing-markers and ages of wine. So we aimed for the evolutions of all extracted ageing-markers during Chinese rice wine ageing, and then distinguished ages using principal component and cluster analysis (PCA, CA).

Long-term environmental enrichment affects microglial morphology in middle age mice.

Aging is associated with increased central nervous system inflammation, in large part due to dysfunctional microglia. Environmental enrichment (EE) provides a model for studying the dynamics of lifestyle factors in the development of age-related neuroinflammation and microglial dysfunction. EE results in improvements in learning and memory, metabolism, and mental health in a variety of animal models. We recently reported that implementing EE in middle age promotes healthy aging. In the present study, we inv...

Working Toward Wellness: TMA's Physician Health and Wellness Exchange Tackles Burnout.

TMA's Physician Health and Wellness Exchange helps physicians find ways to fight burnout.

Facial aging trajectories: A common shape pattern in male and female faces is disrupted after menopause.

Despite variation in lifestyle and environment, first signs of human facial aging show between the ages of 20-30 years. It is a cumulative process of changes in the skin, soft tissue, and skeleton of the face. As quantifications of facial aging in living humans are still scarce, we set out to study age-related changes in three-dimensional facial shape using geometric morphometrics.

A pilot study exploring the relationship between wellness and physical fitness: an examination into autonomic health.

To explore the relationship between physical fitness and wellness in order to determine if perceptions of wellness can be predicted by physical fitness level.

The decline in physical activity in aging people is not modified by gender or the presence of cardiovascular disease.

A physically active lifestyle decreases the progression of atherosclerosis and consequently reduces cardiovascular mortality. However, activity levels are hampered by aging. The association between aging and physical inactivity might be gender-specific or be modified by the presence of cardiovascular disease (CVD). In this study, we investigated if the association between aging and physical inactivity was different between men and women and between primary and secondary prevention patients.

Web-Based Multidomain Lifestyle Programs for Brain Health: Comprehensive Overview and Meta-Analysis.

The number of people living with dementia is increasing worldwide, mainly because of aging of the population. To date, there is no pharmaceutical intervention to delay or treat cognitive decline or dementia. As an estimated one-third of dementia cases might be attributable to modifiable lifestyle factors (such as cognitive and physical activity), multidomain lifestyle interventions are a promising way to maintain or improve brain health. Offering programs online would enable large-scale implementation. An o...

An Intervention to Promote Medication Understanding and Use Self-Efficacy: Design of Video Narratives for Aging Patients at Risk of Recurrent Stroke.

The debilitating effects of recurrent stroke among aging patients have urged researchers to explore medication adherence among these patients. Video narratives built upon Health Belief Model (HBM) constructs have displayed potential impact on medication adherence, adding an advantage to patient education efforts. However, its effect on medication understanding and use self-efficacy have not been tested.

Reducing Cardiovascular Disease Risk for Employees Through Participation in a Wellness Program.

The objective was to evaluate the long-term impact that the University of Rochester Employee Wellness program has made in reducing cardiovascular disease risk. The authors conducted a 5-year retrospective study to measure change in health outcomes for more than 16,000 employees who participated in the program for more than 1 year between January 2013 and December 2017. A logistic regression model was applied to estimate the impact of participation on improvement in cardiovascular disease risk. Statistically...

A mediation analysis of the effect of practical training on the relationship between demographic factors, and bystanders' self-efficacy in CPR performance.

This study examined the mediation effect of practical training on the relationship of demographic characteristics with bystander self-efficacy in cardiopulmonary resuscitation (CPR) performance. We used nationwide, cross-sectional data from the Korea Community Health Survey and analyzed 25,082 Korean adults who participated in CPR training within the last 2 years. A mediation model was applied to explore the pathway from demographic characteristics via CPR practical training to self-efficacy in CPR performa...

Showers, Culture, and Conflict Resolution: A Qualitative Study of Employees' Perceptions of Workplace Wellness Opportunities.

Research on employee opinions of workplace wellness programs is limited.

Immunosenescence: participation of T lymphocytes and myeloid-derived suppressor cells in aging-related immune response changes.

Healthy aging is partly related to appropriate function of the immune system. As already reported, some changes in this system are observed, including reduced number and repertoire of T cells due to thymic involution, accumulation of memory T cells by chronic infections, homeostatic proliferation compensating for the number of naïve T cells, decreased proliferation of T cells against a stimulus, telomere shortening, replicative senescence of the T cells, and inflammaging, besides the accumulation of myeloi...

A head-to-head comparison of the efficacy and safety of ixekizumab and adalimumab in biological-naïve patients with active psoriatic arthritis: 24-week results of a randomised, open-label, blinded-assessor trial.

To compare efficacy and safety of ixekizumab (IXE) to adalimumab (ADA) in biological disease-modifying antirheumatic drug-naïve patients with both active psoriatic arthritis (PsA) and skin disease and inadequate response to conventional synthetic disease-modifying antirheumatic drug (csDMARDs).

The Impact of Wellness on Neural Learning Systems.

Over the past 20 years there has been an increasing push for people to achieve or maintain "wellness" - a state in which one has not only physical but also mental and social well-being. While it may seem obvious that maintaining a state of wellness is beneficial, little research has been done to probe how maintaining a state of wellness impacts our brain. Here, we specifically examined the impact of wellness on a neural system within the medial-frontal cortex responsible for human reinforcement learning. Si...

Breaking a cycle of perceived failure: The process of making changes toward a more balanced lifestyle.

Balancing Everyday Life (BEL) is a new lifestyle intervention for mental health services users, developed to support meaningful engagement in daily activities and a balanced lifestyle. This study aimed at exploring the BEL participants' process of making lifestyle changes.

Association Of Medicare's Annual Wellness Visit With Cancer Screening, Referrals, Utilization, And Spending.

Medicare's annual wellness visit was introduced in 2011 to promote evidence-based preventive care and identify risk factors and undiagnosed conditions in aging adults. Use of the visit has risen steadily since then, yet its benefits remain unclear. Using national Medicare data for 2008-15, we examined claims from fee-for-service Medicare beneficiaries attributed to practices that did or did not adopt the visit. We performed difference-in-differences analysis to compare differential changes in appropriate an...

Glutamate, GABA and presynaptic markers involved in neurotransmission are differently affected by age in distinct mouse brain regions.

Molecular synaptic aging perturbs neurotransmission and decreases the potential for neuroplasticity. The direction and degree of changes observed in aging are often region or cell specific, hampering the generalization of age-related effects. Using real-time PCR and western blot analyses, we investigated age-related changes in several presynaptic markers (VGLUT1, VGLUT2, GAD65, GAD67, VGAT, synaptophysin) involved in the initial steps of glutamatergic and GABAergic neurotransmission, in several cortical reg...

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