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PubMed Journals Articles About "Efficiency Of Coupling Targeted Temperature Management To Brain Temperature In Severe Brain Injury" RSS

19:27 EDT 4th April 2020 | BioPortfolio

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Showing "Efficiency Coupling Targeted Temperature Management Brain Temperature Severe" PubMed Articles 1–25 of 36,000+

Targeted Temperature Management at 33 Versus 36 Degrees: A Retrospective Cohort Study.

To determine the association between targeted temperature management goal temperature of 33°C versus 36°C and neurologic outcome after out-of-hospital cardiac arrest.


Control of Shivering During Targeted Temperature Management.

Targeted temperature management (TTM) is used frequently in patients with a variety of diseases, especially those who have experienced brain injury and/or cardiac arrest. Shivering is one of the main adverse effects of TTM that can often limit its implementation and efficacy. Shivering is the body's natural response to hypothermia and its deleterious effects can negate the benefits of TTM. The purpose of this article is to provide an overview of TTM strategies and shivering management.

Cold fluids for induction of targeted temperature management: A sub-study of the TTH48 trial.

Pre-intensive care unit (ICU) induction of targeted temperature management (TTM) with cold intravenous (i.v.) fluids does not appear to improve outcomes after in out-of-hospital cardiac arrest (OHCA). We hypothesized that this may be due to ineffective cooling and side effects.


Brain temperature of infants with neonatal encephalopathy following perinatal asphyxia calculated using magnetic resonance spectroscopy.

Little is known about brain temperature of neonates during MRI. Brain temperature can be estimated non-invasively with proton Magnetic Resonance Spectroscopy (H-MRS), but the most accurate H-MRS method has not yet been determined. The primary aim was to estimate brain temperature using H-MRS in infants with neonatal encephalopathy following perinatal asphyxia (NE). The secondary aim was to compare brain temperature during MRI with rectal temperatures before and after MRI.

Functional outcomes associated with varying levels of targeted temperature management after out-of-hospital cardiac arrest - An INTCAR2 registry analysis.

Targeted temperature management (TTM) after out-of-hospital cardiac arrest (OHCA) has been recommended in international guidelines since 2005. The TTM-trial published in 2013 showed no difference in survival or neurological outcome for patients randomised to 33 °C or 36 °C, and many hospitals have changed practice. The optimal utilization of TTM is still debated. This study aimed to analyse if a difference in temperature goal was associated with outcome in an unselected international registry populati...

Using Esophageal Temperature Management to Treat Severe Heat Stroke: A Case Report.

Exertional heat stroke (EHS) is defined by a core body temperature that exceeds 40°C with associated central nervous system dysfunction, skeletal muscle injury, and multiple organ damage. The most important initial focus of treatment involves reduction of patient temperature. First approaches to achieve temperature reduction often include ice packs, water blankets, and cold intravenous fluid administration. When these measures fail, more advanced temperature management methods may be deployed but often req...

Safe prognostication following cardiac arrest: the role of the pharmacokinetics of fentanyl in patients treated with targeted-temperature management.

Neurological prognostication following cardiac arrest (CA) is complex and sedative agents may significantly impair responses to clinical examination. This study investigates the elimination of fentanyl in patients treated with targeted temperature management (TTM).

Microbiological profile of nosocomial infections following cardiac arrest: insights from the targeted temperature management (TTM) trial.

Infectious complications frequently occur in intensive care unit patients admitted after out-of-hospital cardiac arrest. There is debate on the effects of temperature management on the incidence of infections, as well as on the efficacy and choice of antibiotic prophylaxis. In this substudy of the targeted temperature management (TTM) trial, we describe the microbiological profile of infectious complications in patients with cardiac arrest and examined the impact of TTM at 33 °C compared to TTM at 36 ...

Prognostication via early computed tomography head in patients treated with targeted temperature management after cardiac arrest.

We evaluated computed tomography head (CTH) imaging obtained prior to targeted temperature management (TTM) in patients after cardiac arrest, and its role in prognostication.

CuMoO4 Bimetallic Nanoparticles, An  Efficient Catalyst  for Room Temperature C-S Cross-coupling of Thiols and Haloarenes.

Cu(II) catalyst is less efficient at room temperature for C-S cross-coupling. C-S cross-coupling by Cu(II) catalyst at  room temperature is not reported. But doping of copper  with  molybdenum metal has been realized here to be more efficient  for C-S cross-coupling in comparison to general Cu(II) catalyst. The doped catalyst CuMoO4 nanoparticle is found to be more efficient than copper. The catalyst works with mild condition without any ligand at room temperature.  The catalyst is recyclable and effec...

Efficacy of the cooling method for targeted temperature management in post-cardiac arrest patients: a systematic review and meta-analysis.

This review aimed to compare the efficacy of endovascular cooling devices (ECD), such as Thermogard®, with surface cooling devices (SCD), such as Arctic Sun®, in reducing mortality and improving neurological status for patients with post-cardiac arrest undergoing targeted temperature management.

Ultradian oscillations in brain temperature in sheep: implications for thermoregulatory control?

We compared body temperature patterns and selective brain cooling (SBC) in eight adult female sheep in an indoor (22-25 °C) and outdoor (mean ~ 21 °C) environment, by measuring brain, carotid arterial, and jugular venous blood temperatures at 5-min intervals using implanted data loggers. To investigate whether ultradian oscillations in brain temperature had thermoregulatory consequences for the sheep, we determined the cranial arterio-venous (AV) temperature difference as an indicator of respiratory...

Meta-analysis of targeted temperature management in animal models of cardiac arrest.

Targeted temperature management (TTM) of 32 to 34 °C has been the standard treatment for out-of-hospital cardiac arrest since clinical trials in 2002 indicated benefit on survival and neurological outcome. In 2013, a clinical trial showed no difference in outcome between TTM of 33 °C and TTM of 36 °C. In this meta-analysis, we investigate the evidence for TTM in animal models of cardiac arrest.

Improvement of Consciousness before Initiating Targeted Temperature Management.

Following cardiac arrest, return of spontaneous circulation (ROSC) in patients may be followed by spontaneous neurological recovery, which may decrease the potential adverse effects of treatments in post-cardiac arrest care, including those of Targeted Temperature Management (TTM). We investigated the percentage of post-arrest patients who experienced spontaneous neurological recovery, and the characteristics and neurological outcomes of these patients.

The usefulness of neuron-specific enolase in cerebrospinal fluid to predict neurological prognosis in cardiac arrest survivors who underwent target temperature management: a prospective observational study.

Cerebrospinal fluid (CSF) neuron-specific enolase (NSE) levels increase ahead of serum NSE levels in patients with severe brain injury. We examined the prognostic performance between CSF NSE and serum NSE levels in out-of-cardiac arrest (OHCA) survivors who had undergone target temperature management (TTM).

The Effects of Abnormal Body Temperature on the Prognosis of Patients with Septic Shock.

We aimed to use temperature and the area under temperature curve to represent the severity of abnormal body temperature of patients with septic shock and to observe their impact on the prognosis. Five hundred twenty-eight adult patients with septic shock admitted to intensive care unit (ICU) were analyzed. Within the first 24 hours and throughout the period in ICU, the maximum temperature (24hT, T), lowest temperature (24hT, T), and the temperature range (24hT, T) were aggregated. Patients were divided into...

Sinus Bradycardia During Targeted Temperature Management: A Systematic Review and Meta-Analysis.

The beneficial effect of sinus bradycardia during targeted temperature management (TTM) in cardiac arrest patients remains doubtful. We aimed to investigate the impact of sinus bradycardia on survival and neurological outcome. MEDLINE (PubMed), Cochrane, Google Scholar, and ClinicalTrials.gov databases were searched for studies reporting on comatose postcardiac arrest patients presenting sinus bradycardia during TTM. Outcomes were the 180-day survival and final neurologic function assessed by the Cerebral P...

Long-term survival in out-of-hospital cardiac arrest patients treated with targeted temperature control at 33 °C or 36 °C: A national registry study.

There are limited data on long-term outcome in out-of-hospital cardiac arrest patients following the treatment shift of target temperature management (TTM) from 33 °C to 36 °C outside the controlled settings of randomised trials. The aim of this study was to evaluate the adherence to TTM guidelines after the publication of the TTM trial and if the change in temperature level influence six-month survival.

A novel safety treatment strategy of DEHP-rich flexible polyvinyl chloride waste through low-temperature critical aqueous ammonia treatment.

Flexible polyvinyl chloride (f-PVC) contains high content of plasticizers and chlorine. Improper treatment of waste f-PVC can easily lead to resource wasting and bring environmental risks. In this work, a novel strategy for resource recycling and dechlorination of waste f-PVC containing high content of di-(2-ethylhexyl) phthalate (DEHP) was developed by using low-temperature critical aqueous ammonia (LCA) process. The LCA treatment of waste DEHP-rich f-PVC (WDP) was performed at the temperature range of 200...

Critical Update on the Third Edition of the Guidelines for Managing Severe Traumatic Brain Injury in Children.

Severe traumatic brain injury (TBI) is associated with high rates of death and disability. As a result, the revised guidelines for the management of pediatric severe TBI address some of the previous gaps in pediatric TBI evidence and management strategies targeted to promote overall health outcomes.

Targeted Temperature Management after cardiac arrest: and the optimal target is….?

Salinity and low temperature effects on the performance of column biochemical reactors for the treatment of acidic and neutral mine drainage.

Passive biochemical reactors (PBRs) represent a promising option for the treatment of mine drainage. In this study, the influence of temperature (22 and 5 °C), salinity (0 and 20 g/L) and hydraulic retention time (HRT) on the efficiency of PBRs for the treatment of acidic and neutral mine drainage (AMD and NMD) was evaluated. To do so, eight 11 L PBRs were set-up and operated with vertically upward flow. Synthetic AMD and NMD, with two salinities (0 and 20 g/L), were tested at ambient temperature (...

Clinical Q & A: Translating Therapeutic Temperature Management from Theory to Practice.

Anesthetic Management of Patient With Dravet Syndrome: A Case Report.

Dravet syndrome (DS) is a rare and severe form of epilepsy that begins in infancy. This is particularly burdensome because repeated epileptic seizures lead to cognitive decline. We describe the case of a 12-year-old girl who was diagnosed with DS and was scheduled to have gingival reduction around her mandibular molars. Despite the patient being intellectually disabled, she was able to cooperate somewhat during medical procedures, including intravenous cannulation. Under the assumption that the major proble...

First principle study of temperature dependent magneto resistance and spin filtration effect in WS2 nanoribbon.

An applicable use of density functional theory (DFT) along with non-equilibrium Green's function (NEGF) is done for exploring temperature dependent spin electron transport nature in ferromagnetic Tungsten Disulphide (WS2) nanoribbon. To demonstrate the effect of temperature on spin filtration and spin Seebeck effect, vital parameters like spin polarized current and spin filtration efficiency are evaluated. Spin filtration efficiency of around ~95% is obtained in the high temperature difference range. High t...


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