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PubMed Journals Articles About "Evaluation Of The Muscle Strength And Motor Ability In Children With Spinal Muscle Atrophy(SMA) Treated With Valproic Acid" RSS

22:22 EST 20th February 2019 | BioPortfolio

Evaluation Of The Muscle Strength And Motor Ability In Children With Spinal Muscle Atrophy(SMA) Treated With Valproic Acid PubMed articles on BioPortfolio. Our PubMed references draw on over 21 million records from the medical literature. Here you can see the latest Evaluation Of The Muscle Strength And Motor Ability In Children With Spinal Muscle Atrophy(SMA) Treated With Valproic Acid articles that have been published worldwide.

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Showing "Evaluation Muscle Strength Motor Ability Children With Spinal" PubMed Articles 1–25 of 28,000+

Strength Training Effects on Muscle Forces and Contributions to Whole-Body Movement in Cerebral Palsy.

Strength training is often prescribed for children with cerebral palsy (CP); however, links between strength gains and mobility are unclear. Nine children (age 14 ± 3 years; GMFCS I-III) with spastic CP completed a 6-week strength-training program. Musculoskeletal gait simulations were generated for four children to assess training effects on muscle forces and function. There were increases in isometric joint strength, but no statistical changes in fast-as-possible walking speed or endurance after tr...


Psychometric Evaluation of 2 New Upper Extremity Functional Strength Tests in Children With Cerebral Palsy.

For children with unilateral spastic cerebral palsy (USCP), reduced muscle strength may lead to activity limitations. However, despite existence of many upper limb strength measures, none measure strength in the context of functional activities in which the strength must be maintained for several seconds.

Early clinical evaluation of total hip arthroplasty by three-dimensional gait analysis and muscle strength testing.

As improvement of gait is an important reason for patients to undergo total hip arthroplasty (THA) and they generally tend to evaluate its success based on postoperative walking ability, objective functional evaluation of postoperative gait is important. However, the patient's normal gait before osteoarthritis is unknown and the changes that will occur postoperatively are unclear. We investigated the change in gait and hip joint muscle strength after THA by using a portable gait rhythmograph (PGR) and muscl...


Using Motor Imagery Training to Increase Quadriceps Strength: A Pilot Study.

Motor imagery training implements neural adaptation theory to improve muscle strength without physically performing muscle contractions. To date, motor imagery training research regarding the efficacy of improving torque of the quadriceps over a brief training period is limited.

Developmental Trajectories and Reference Percentiles for Range of Motion, Endurance, and Muscle Strength of Children with Cerebral Palsy.

Children with cerebral palsy (CP) frequently present with secondary impairments in spinal alignment and extremity range of motion, endurance for activity, and muscle strength. Creation of developmental trajectories for these impairments will help guide clinical decision-making.

Motor ability and working memory in Omani and German primary school-aged children.

This study investigated the motor ability and working memory performance of Omani and German primary school-aged children. One hundred eighty-five children from public schools participated in a gross motor test that integrated whole body coordination, three different ball tasks, and a 20-meter run. Furthermore, they completed four working memory tests (the Digit-Span Test forward and backwards and the Corsi Block-Tapping Test forward and backwards). Two MANOVAS with the different motor and working memory te...

The increase in muscle force after 4 weeks of strength training is mediated by adaptations in motor unit recruitment and rate coding.

Previous studies have indicated that several weeks of strength training is sufficient to elicit significant adaptations in the neural drive sent to the muscles. There are few data, however, on the changes elicited by strength training in the recruitment and rate coding of motor units during voluntary contractions. We show for the first time that the discharge characteristics of motor units in the tibialis anterior muscle tracked across the intervention are changed by 4 weeks of strength training with isome...

Influence of hip joint dysfunction on motor disorders in Japanese patients with osteoarthritis of the hip: Assessment of the JHEQ and GLFS-25 scores and hip muscle strength.

Motor disorders are caused by orthopedic problems that are mainly related to aging. These disorders can lead to a decline of physical activity and impairment of ADL. When evaluating a patient's motor function after treatment, it is necessary to determine whether or not the level of function is age-appropriate. To investigate the influence of hip joint dysfunction on motor disorders, we determined the JHEQ and GLFS-25 scores and performed muscle strength testing in female patients with hip osteoarthritis.

Characterizing the Motor Skills in Children with Specific Language Impairment.

Specific language impairment (SLI) is characterized by deficits in language ability. However, studies have also reported motor impairments in SLI. It has been proposed that the language and motor impairments in SLI share common origins. This exploratory study compared the gross, fine, oral, and speech motor skills of children with SLI and children with typical development (TD) to determine whether children with SLI would exhibit difficulties on particular motor tasks and to inform us about the underlying co...

Improvement of motor function induced by skeletal muscle contraction in spinal cord-injured rats.

The involvement of neurotrophic factors such as brain-derived neurotrophic factor (BDNF) in functional recovery after spinal cord injury (SCI) by treadmill training has been suggested. The precise mechanism is poorly understood. However, muscle-derived bioactive molecules (myokines) are known to be produced by muscle contraction. Although BDNF is a myokine and is considered to be a potential mediator of neuroplasticity following exercise, its contribution to motor function recovery after SCI has not yet bee...

Genetic variant in the β -Adrenergic receptor (Arg16Gly) influences fat free mass, muscle strength, and motor unit behavior in young men.

What is the central question of this study? Does a common genetic variant in the β2-adrenergic receptor (AR) have functional effects on skeletal muscle function in young, healthy men? What is the main finding and its importance? This study provides preliminary evidence that β2-AR Arg16Gly genotype has a significant effect on fat free mass, muscle strength, and motor unit behavior in recreationally-trained men. These data may have important clinical and exercise-related implications. For example, β2-AR (r...

Cell cycle inhibitors protect motor neurons in an organoid model of Spinal Muscular Atrophy.

Spinal Muscular Atrophy (SMA) is caused by genetic mutations in the SMN1 gene, resulting in drastically reduced levels of Survival of Motor Neuron (SMN) protein. Although SMN is ubiquitously expressed, spinal motor neurons are one of the most affected cell types. Previous studies have identified pathways uniquely activated in SMA motor neurons, including a hyperactivated ER stress pathway, neuronal hyperexcitability, and defective spliceosomes. To investigate why motor neurons are more affected than other n...

Motor imagery ability assessments in four disciplines: protocol for a systematic review.

Motor imagery (MI) is a very popular and well-accepted technique in different disciplines. Originating from sport and psychology, MI is now also used in the field of medicine and education. Several studies confirmed the benefits of MI to facilitate motor learning and skill acquisition. The findings indicated that individual's MI ability might influence the effectiveness of MI interventions. Over the last two centuries, researchers have developed several assessments to evaluate MI's abstract construct. Howev...

Brain network connectivity associated with anticipatory postural control in children and adults.

Internal models provide a coherent framework for understanding motor behavior. Examples for the use of internal models include anticipatory postural adjustments (APAs), where the individual anticipates and cancels out the destabilizing effect of movement on body posture. Yet little is known about the functional changes in the brain supporting the development of APAs. Here, we addressed this issue by relating individual differences in APAs as assessed during bimanual load lifting to interindividual variation...

The motor unit number index (MUNIX) profile of patients with adult spinal muscular atrophy.

Objective of this study is the comprehensive characterisation of motor unit (MU) loss in type III and IV Spinal Muscular Atrophy (SMA) using motor unit number index (MUNIX), and evaluation of compensatory mechanisms based on MU size indices (MUSIX).

Motor unit action potential amplitudes and firing rates during repetitive muscle actions of the first dorsal interosseous in children and adults.

Previous research has indicated greater muscle activation is needed for children (CH) to match relative intensity submaximal contractions in comparison with adults (AD). However, no study has compared motor unit (MU) firing and recruitment patterns between children and adults. Therefore, MU action potential amplitudes (MUAP) and firing rates were examined during two repetitive submaximal contractions of the first dorsal interosseous in children and adults.

C5 pure motor spinal cord injury: A case with a rare manifestation of cervical spinal cord injury.

We report an extremely rare case showing a fifth cervical spine (C5) level pure motor cervical spinal cord injury (SCI). A 55-year-old-man lost consciousness and fell into a bathtub. Immediately after regaining consciousness, the patient had right arm drop alone. He was referred to our department for investigation of right arm drop 4 months later. Neurological examination revealed motor weakness of the right deltoid muscle. MRI of the cervical spine revealed a C3-4 level central disc herniation compressin...

Hitting the Target: Mathematical Attainment in Children Is Related to Interceptive-Timing Ability.

Interceptive timing is a fundamental ability underpinning numerous actions (e.g., ball catching), but its development and relationship with other cognitive functions remain poorly understood. Piaget suggested that children need to learn the physical rules that govern their environment before they can represent abstract concepts such as number and time. Thus, learning how objects move in space and time may underpin the development of related abstract representations (i.e., mathematics). To test this hypothes...

Quantitative evaluation of hand motor function using a gyrosensor in mild and moderate carpal tunnel syndrome.

The aim of this study was to determine whether carpal tunnel syndrome (CTS) patients manifest changes in early-stage motor function and to investigate the utility of a gyrosensor for quantitative evaluation of motor function.

Effect of pulsed transcranial ultrasound stimulation at different number of tone-burst on cortico-muscular coupling.

Pulsed transcranial ultrasound stimulation (pTUS) can modulate the neuronal activity of motor cortex and elicit muscle contractions. Cortico-muscular coupling (CMC) can serve as a tool to identify interaction between the oscillatory activity of the motor cortex and effector muscle. This research aims to explore the neuromodulatory effect of low-intensity, pTUS with different number of tone burst to neural circuit of motor-control system by analyzing the coupling relationship between motor cortex and tail mu...

Trunk Muscle Strength After Lumbar Spine Fusion: A 12-Month Follow-up.

The aim of this study was to investigate the changes in trunk muscle strength 12 months after LSF, compared to preoperative strength.

The differences in the structure of the motor nucleus of the medial gastrocnemius muscle in male and female rats.

There are many reports describing sexual dissimilarities in the CNS, particularly in the brain and cortical regions. However, knowledge regarding sexual dissimilarities in the spinal cord and in particular in the hindlimb muscle-motoneuron connectivity controlling locomotion is limited. In order to recognise sex differences in the architecture of the medial gastrocnemius (MG) motor nucleus in rats of the same age, retrograde-labelled motoneurons were identified following a bath of the proximal stump of the ...

The effects of aging on cortico-spinal excitability and motor memory consolidation.

We investigated whether cortico-spinal excitability (CSE), a marker of synaptic plasticity, is associated with age-related differences in the consolidation of motor memory. Young and older participants practiced a visuomotor tracking task. Skill retention was assessed 8 and 24 hours after motor practice. Transcranial magnetic stimulation applied over the primary motor cortex at rest and during an isometric muscle contraction was used to assess absolute and normalized to baseline CSE at different points aft...

Mild-to-Moderate Hallux Valgus Does Not Induce a Decrease of Ankle Muscle Strength in Middle-Aged Japanese Women: A Comparative Study.

Extreme hallux valgus has been documented to be related to lower functional ability and health-related quality of life. It also has a negative effect on foot structure and biomechanical characteristics, which in turn may affect muscle strength in the foot and ankle. Thus, the purposes of this study were to determine whether there is a difference of ankle muscle strength in varied hallux valgus deformities and to investigate correlations between hallux valgus angles and ankle muscle strength. Hallux valgus a...

Differences in elbow extensor muscle characteristics between resistance-trained men and women.

Muscular strength is suggested to be dependent upon muscle characteristics. Yet, sex-specific relationships of muscle characteristics to strength in the resistance-trained require investigation. Therefore, the purpose was to evaluate sex differences in muscle characteristics and isometric strength in the elbow extensors, as well as their respective associations.


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