PubMed Journals Articles About "FIT 2 SIT - Are Metabolic Responses To Sitting/Light Breaks Mediated By Fitness?" RSS

01:09 EST 10th December 2018 | BioPortfolio

FIT 2 SIT - Are Metabolic Responses To Sitting/Light Breaks Mediated By Fitness? PubMed articles on BioPortfolio. Our PubMed references draw on over 21 million records from the medical literature. Here you can see the latest FIT 2 SIT - Are Metabolic Responses To Sitting/Light Breaks Mediated By Fitness? articles that have been published worldwide.

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Showing "Metabolic Responses Sitting Light Breaks Mediated Fitness" PubMed Articles 1–25 of 23,000+

Does breaking up prolonged sitting when sleep restricted affect postprandial glucose responses and subsequent sleep architecture? - a pilot study.

This pilot study investigated the impact of breaking up prolonged sitting with light-intensity walking on postprandial glucose responses and sleep architecture. In a randomized, counterbalanced, crossover design, six healthy males completed a sitting condition and an active condition (sitting interrupted with light-intensity walking) for three consecutive days, following 5-h sleep opportunities at night. Postprandial glucose response and sleep (time spent in all stages) was assessed. Breaking up prolonged s...

The Acute Metabolic and Vascular Impact of Interrupting Prolonged Sitting: A Systematic Review and Meta-Analysis.

The aim was to conduct a systematic review and meta-analysis analyzing the impact of up to 24 h of prolonged sitting on postprandial glucose, insulin and triglyceride responses, blood pressure and vascular function, in comparison to sitting interrupted with light- to moderate-intensity physical activity.

Regular walking breaks prevent the decline in cerebral blood flow associated with prolonged sitting.

Decreased cerebrovascular blood flow and function are associated with lower cognitive functioning and increased risk of neurodegenerative diseases. Prolonged sitting impairs peripheral blood flow and function, but its effects on the cerebrovasculature are unknown. This study explored the effect of uninterrupted sitting and breaking up sitting time on cerebrovascular blood flow and function of healthy desk workers. Fifteen participants (10 male, 35.8{plus minus}10.2 years, BMI: 25.5{plus minus}3.2 kg∙m) co...

Metabolic effects of breaking prolonged sitting with standing or light walking in older South Asians and White Europeans: a randomized acute study.

Prolonged sitting is common in older adults and associated with insulin resistance and poor cardiometabolic health. We investigate whether breaking prolonged sitting with regular short bouts of standing or light walking improves postprandial metabolism in older white European and South Asian adults and whether effects are modified by ethnic group.

Associations between activity patterns and cardio-metabolic risk factors in children and adolescents: A systematic review.

Total volumes of physical activity and sedentary behaviour have been associated with cardio-metabolic risk profiles; however, little research has examined whether patterns of activity (e.g., prolonged bouts, frequency of breaks in sitting) impact cardio-metabolic risk. The aim of this review was to synthesise the evidence concerning associations between activity patterns and cardio-metabolic risk factors in children and adolescents aged 5-19 years.

Sitting cross-legged for 30 minutes alters lower limb shear stress pattern but not flow-mediated dilation or arterial stiffness.

Prolonged sitting decreases lower limb endothelial function via sustained reductions in mean shear rate. We tested whether 30 minutes of sitting cross-legged differentially impacts superficial femoral artery shear rate pattern, flow-mediated dilation (FMD) and leg pulse-wave velocity (PWV) compared to sitting flat-footed. Sitting cross-legged attenuated the reduction in mean and antegrade shear rate and increased arterial pressure compared to sitting flat-footed. Superficial femoral artery FMD and leg PWV w...

Breaking up sitting time after stroke (BUST-stroke).

Objectives People with stroke sit for long periods each day, which may compromise blood glucose control and increase risk of recurrent stroke. Studies in other populations have found regular activity breaks have a significant immediate (within-day) positive effect on glucose metabolism. We examined the effects of breaking up uninterrupted sitting with frequent, short bouts of light-intensity physical activity in people with stroke on post-prandial plasma glucose and insulin. Methods Randomized within-partic...

Sitting to standing postural changes: Energy expenditure and a possible mechanism to alleviate sedentary behavior.

Background and aims Sedentary lifestyles have recently been identified as potential mechanism for obesity and associated metabolic diseases linked to ill health. The aim of this study was to investigate the effects of standing and sitting-standing positional changes on energy cost and consequently interrupting sedentary sitting time while working. Methods A total of 26 healthy male volunteers performed normal typing and editing work for 100 min under three conditions. The conditions included sustained sitt...

Feasibility, acceptability, and potential efficacy of a childcare-based intervention to reduce sitting time among pre-schoolers: A pilot randomised controlled trial.

The aim of this study was to test the feasibility, acceptability and potential efficacy of a childcare-based intervention to reduce total and prolonged sitting time in pre-schoolers. Four centres and 115 pre-schoolers (44 % boys; 4.1y) participated in a 3-month, 2-arm pilot cluster randomised controlled trial. Feasibility and acceptability were assessed through observations and semi-structured interviews. Sitting time, and breaks and bouts of sitting during childcare were assessed using an activPAL acceler...

Integrative analysis of fitness and metabolic effects of plasmids in Pseudomonas aeruginosa PAO1.

Horizontal gene transfer (HGT) mediated by the spread of plasmids fuels evolution in prokaryotes. Although plasmids provide bacteria with new adaptive genes, they also produce physiological alterations that often translate into a reduction in bacterial fitness. The fitness costs associated with plasmids represent an important limit to plasmid maintenance in bacterial communities, but their molecular origins remain largely unknown. In this work, we combine phenomics, transcriptomics and metabolomics to study...

Photoreceptor-mediated regulation of the COP1/SPA E3 ubiquitin ligase.

Plants have evolved specific photoreceptors that capture informational cues from sunlight. The phytochrome, cryptochrome, and UVR8 photoreceptors perceive red/far-red, blue/UV-A, and UV-B light, respectively, and control overlapping photomorphogenic responses important for plant growth and development. A major repressor of such photomorphogenic responses is the E3 ubiquitin ligase formed by CONSTITUTIVELY PHOTOMORPHOGENIC 1 (COP1) and SUPPRESSOR OF PHYA-105 (SPA) proteins, which acts by regulating the stabi...

A Defective Pentose Phosphate Pathway Reduces Inflammatory Macrophage Responses during Hypercholesterolemia.

Metabolic reprogramming has emerged as a crucial regulator of immune cell activation, but how systemic metabolism influences immune cell metabolism and function remains to be investigated. To investigate the effect of dyslipidemia on immune cell metabolism, we performed in-depth transcriptional, metabolic, and functional characterization of macrophages isolated from hypercholesterolemic mice. Systemic metabolic changes in such mice alter cellular macrophage metabolism and attenuate inflammatory macrophage r...

Sport Participation and Metabolic Risk During Adolescent Years: A Structured Equation Model.

Sports practice during childhood can influence health indicators in later ages through direct and indirect pathways. Thus, this study aimed to test direct and indirect pathways to the association between sports practice in childhood and metabolic risk in adolescence, adopting physical activity, adiposity, and cardiorespiratory fitness at adolescence as potential mediators. This cross-sectional study with retrospective information was conducted with 991 adolescents (579 girls, 412 boys) aged 10 to 16 y. Spor...

Host NAD+ metabolism and infections: therapeutic implications.

Nicotinamide adenine dinucleotide (NAD+) is both a crucial coenzyme and a cosubstrate for various metabolic reactions in all living cells. Maintenance of NAD+ levels is essential for cell energy homeostasis, survival, proliferation and function. Mounting evidence points to NAD+ as one of the major modulators of immuno-metabolic circuits, thus regulating immune responses and functions. Recent studies delineate impaired host NAD+ metabolism during chronic infections and inflammation, suggesting NAD+ replenish...

Response anisocoria in the pupillary light and darkness reflex.

The pupil constricts or dilates in response to a luminance increase or decrease, and these transient pupillary responses are controlled by the parasympathetic and sympathetic pathways. Although pupillary responses of the two eyes are highly correlated, they are not always identical (referred to as anisocoria). For example, there are unequal direct and consensual pupillary constriction responses after an increase in luminance to one eye. While contraction anisocoria (i.e. constriction) has been demonstrated ...

ROC75 Functions as an Attenuator of the Circadian Clock to Control Photoprotective LHCSR3 Gene in Chlamydomonas reinhardtii.

Strong light intensity leads to harmful overexcitation of the photosystems in green algae. In Chlamydomonas reinhardtii, LHCSR3 is required for the rapid protective response known as energy-dependent quenching (qE). Because the majority of photoacclimation analysis has been conducted under controlled laboratory conditions, physiological responses to natural environmental changes such as light/dark cycles have not been examined in detail. Regarding fitness in higher plants and microalgae, light-dark cycles r...

Metabolic Profile and Performance Responses During Two Consecutive Sessions of Sprint Interval Training.

Malta, ES, Brisola, GMP, de Poli, RAB, Dutra, YM, Franchini, E, and Zagatto, AM. Metabolic profile and performance responses during two consecutive sessions of sprint interval training. J Strength Cond Res XX(X): 000-000, 2018-The study aimed to (a) typify the cardiorespiratory, metabolic, and performance responses during a single sprint interval training (SIT) session, (b) investigate the interference of 2 subsequent sessions on cardiorespiratory, metabolic, and performance responses, and (c) verify the re...

Physical fitness and activity, metabolic profile, adipokines and endothelial function in children.

The prevalence of obesity is increasing. The aim of this study was to investigate if there is endothelial dysfunction in children with normal or excess weight, and whether the metabolic profile, adipokines, and endothelial dysfunction would be more strongly associated with physical fitness or with physical activity levels.

Do different sitting postures affect spinal biomechanics of asymptomatic individuals?

Static sitting is thought to be related to low back pain. Of various common seated postures, slouched sitting has been suggested to cause viscoelastic creep. This, in turn, may compromise trunk muscle activity and proprioception, and heightening the risk of low back pain. To date, no research has evaluated immediate and short-term effects of brief exposures to different sitting postures on spinal biomechanics and trunk proprioception.


Prolonged sitting contributes to cardiovascular disease (CVD) risk. The underlying mechanisms are unknown, but may include changes in arterial function and vasoactive mediators. We examined the effects of prolonged unbroken sitting, relative to regular active interruptions to sitting time, on arterial function in adults at increased CVD risk. In a randomized crossover trial, 19 sedentary overweight/obese adults (mean±SD 57±12 yrs), completed two laboratory-based conditions: five hours uninterrupted sittin...

Acute Physical Effort Increases Sympathovagal Balance Responses to Autonomic Stimulation in Metabolic Syndrome.

There is little evidence of how metabolic syndrome (MS) affects sympathovagal balance responses to acute physical effort (APE) and autonomic stimulation (AS). This study aimed to evaluate the heart rate variability (HRV) responses to the combined APE and AS challenges.

Sitting Our Lives Away.

Exercise may not mitigate the ill effects of prolonged sitting.

activPAL-measured sitting levels and patterns in 9-10 years old children from a UK city.

There is insufficient evidence of sitting time in UK children from validated objective measures. This study explored sitting patterns in primary school children from Bradford, UK, using the validated activPAL inclinometer.

Circadian modulation of light-evoked avoidance/attraction behavior in Drosophila.

Many insects show strong behavioral responses to short wavelength light. Drosophila melanogaster exhibit Cryptochrome- and Hyperkinetic-dependent blue and ultraviolet (UV) light avoidance responses that vary by time-of-day, suggesting that these key sensory behaviors are circadian regulated. Here we show mutant flies lacking core clock genes exhibit defects in both time-of-day responses and valence of UV light avoidance/attraction behavior. Non-genetic environmental disruption of the circadian clock by cons...

Innate Immune Signaling in Nonalcoholic Fatty Liver Disease and Cardiovascular Diseases.

The physiological significance of innate immune signaling lies primarily in its role in host defense against invading pathogens. It is becoming increasingly clear that innate immune signaling also modulates the development of metabolic diseases, especially nonalcoholic fatty liver disease and cardiovascular diseases, which are characterized by chronic, low-grade inflammation due to a disarrangement of innate immune signaling. Notably, recent studies indicate that in addition to regulating canonical innate i...

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