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PubMed Journals Articles About "Formal Notice Tendered Licensing Agreement Termination" RSS

03:24 EST 17th December 2018 | BioPortfolio

Formal Notice Tendered Licensing Agreement Termination PubMed articles on BioPortfolio. Our PubMed references draw on over 21 million records from the medical literature. Here you can see the latest Formal Notice Tendered Licensing Agreement Termination articles that have been published worldwide.

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Showing "Formal notice tendered licensing agreement termination" PubMed Articles 1–25 of 2,300+

Sexual well-being after first trimester termination of pregnancy: secondary analysis of a randomised contraceptive trial.

Although termination of pregnancy is one of the most common procedures worldwide, little is known about sexual well-being after termination of pregnancy. The objective of this study was to assess sexual well-being after termination of pregnancy, and factors affecting it during one-year follow-up.


Correction notice to paper "Agreement of treatment effects for mortality from routinely collected data and subsequent randomized trials: meta-epidemiological survey".

Eye-tracking in dentistry: What do children notice in the dentist? Short title: What children notice in the dentist.

To determine, using eye-tracking technology, what children notice the most when they look at the dentist.


Elongation/Termination Factor Exchange Mediated by PP1 Phosphatase Orchestrates Transcription Termination.

Termination of RNA polymerase II (Pol II) transcription is a key step that is important for 3' end formation of functional mRNA, mRNA release, and Pol II recycling. Even so, the underlying termination mechanism is not yet understood. Here, we demonstrate that the conserved and essential termination factor Seb1 is found on Pol II near the end of the RNA exit channel and the Rpb4/7 stalk. Furthermore, the Seb1 interaction surface with Pol II largely overlaps with that of the elongation factor Spt5. Notably, S...

Regulated chloroplast transcription termination.

Transcription termination by the RNA polymerase (RNAP) is a fundamental step of gene expression that involves the release of the nascent transcript and dissociation of the RNAP from the DNA template. However, the functional importance of termination extends beyond the mere definition of the gene borders. Chloroplasts originate from cyanobacteria and possess their own gene expression system. Plastids have a unique hybrid transcription system consisting of two different types of RNAPs of dissimilar phylogenet...

Saccade-based termination responses in macaque V1 and visual perception.

Neurons in visual areas of the brain are generally characterized by the increase in firing rate that occurs when a stimulus is flashed on in the receptive field (RF). However, neurons also increase their firing rate when a stimulus is turned off. These "termination responses" or "after-discharges" that occur with flashed stimuli have been observed in area V1 and they may be important for vision as stimulus terminations have been shown to influence visual perception. The goal of the present study was to dete...

Cognition, emotion, and behaviour in women undergoing pregnancy termination for foetal anomaly: A grounded theory analysis.

To understand the cognition, emotions, and behaviour of women who had recently undergone termination due to a foetal anomaly. In this study, we developed and tested a theoretical model to describe how women went through the process after termination.

Moral licensing, instrumental apology and insincerity aversion: Taking Immanuel Kant to the lab.

Moral licensing, equivalently called "self-licensing", is the instrumental use of a Good Act to cover up a Bad Act. This paper's thesis is that "instrumental apology" i.e., bad-faith apology, is a case of moral licensing. A decision maker may issue an apology (Good Act) after committing a Bad Act, but if the decision maker uses the apology instrumentally, he or she is using the apology to justify the Bad Act. Hence, the apology is insincere. Sincerity is the fine line between a good-faith apology or, more g...

Dynamics of ribosomes and release factors during translation termination in .

Release factors RF1 and RF2 promote hydrolysis of peptidyl-tRNA during translation termination. The GTPase RF3 promotes recycling of RF1 and RF2. Using single molecule FRET and biochemical assays, we show that ribosome termination complexes that carry two factors, RF1-RF3 or RF2-RF3, are dynamic and fluctuate between non-rotated and rotated states, whereas each factor alone has its distinct signature on ribosome dynamics and conformation. Dissociation of RF1 depends on peptide release and the presence of RF...

How deep do we dig? Formal explanations as placeholders for inherent explanations.

Formal explanations (e.g., "Mittens has whiskers because she's a cat") pose an intriguing puzzle in human cognition: they seem like little more than tautologies, yet they are surprisingly commonplace and natural-sounding. To resolve this puzzle, we hypothesized that formal explanations constitute an implicit appeal to a category's inherent features rather than simply to the category itself (as their explicit content would suggest); the latter is just a placeholder. We conducted a series of eight experiments...

Implementation Strategies Used by States to Support Physical Activity Licensing Standards for Toddlers in Early Care and Education Settings: An Exploratory Qualitative Study.

Child care settings have been a target for childhood obesity prevention efforts; changing licensing standards to require physical activity (PA)-related best practices is one strategy being used by states. The mechanisms used to support implementation by providers remain understudied, despite the potential for these efforts to significantly impact child-level outcomes. This qualitative study explored the mechanisms used and any outstanding challenges to implementation experienced by US states with one specif...

EVIDENCE THAT DYNORPHIN ACTS UPON KNDy AND GnRH NEURONS DURING GnRH PULSE TERMINATION IN THE EWE.

A subpopulation of neurons located within the arcuate nucleus, co-localizing kisspeptin, neurokinin B, and dynorphin, (termed KNDy neurons) are key mediators of pulsatile gonadotropin-releasing hormone (GnRH) secretion. The KNDy model of GnRH pulse generation proposes that dynorphin (Dyn) terminates each pulse. However, it is unknown where and when during a pulse, Dyn is released to inhibit GnRH secretion. Dyn acts via the kappa opioid receptor (KOR), and KOR is present in KNDy and GnRH neurons in the sheep...

Compliance with the U.S. Nuclear Regulatory Commission Revised Licensing Guidance for Radioactive Seed Localization.

The use of radioactive seed localization (RSL) as a reliable alternative to wire localization (WL) for guiding the surgical excision of non-palpable lesions has become more popular because of its demonstrated advantages for both the patient and surgeon. RSL is regulated under 10 CFR 35.1000 (Other Medical Uses) for which the U.S. Nuclear Regulatory Commission (U.S. NRC) issued its original licensing guidance entitled "I-125 and Pd-103 Low Dose Rate Brachytherapy Seeds Used for Localization of Non-palpable L...

'A true partner around the table?' Perceptions of how to strengthen public health's contributions to the alcohol licensing process.

There are increased opportunities for public health practitioners (PHPs) in England to shape alcohol availability and reduce harms through a statutory role in licensing processes in local government. However, how public health can effectively influence alcohol licence decision-making is little understood.

Frailty differences in older adults' use of informal and formal care.

This study examines different combinations of informal and formal care use of older adults and investigates whether these combinations differ in terms of need for care (physical and psychological frailty) and enabling factors for informal and formal care use (social and environmental frailty).

Visualization of translation termination intermediates trapped by the Apidaecin 137 peptide during RF3-mediated recycling of RF1.

During translation termination in bacteria, the release factors RF1 and RF2 are recycled from the ribosome by RF3. While high-resolution structures of the individual termination factors on the ribosome exist, direct structural insight into how RF3 mediates dissociation of the decoding RFs has been lacking. Here we have used the Apidaecin 137 peptide to trap RF1 together with RF3 on the ribosome and visualize an ensemble of termination intermediates using cryo-electron microscopy. Binding of RF3 to the ribo...

Examining Demographics, Prior Academic Performance, and United States Medical Licensing Examination Scores.

To examine whether demographic differences exist in United States Medical Licensing Examination (USMLE) examination scores and the extent to which any differences are explained by students' prior academic achievement.

Exploration of M(100)-2×1 (M=Si, Ge) surface termination through hydrogen passivation using ethane and ammonia-borane derivatives: A theoretical approach.

Termination process of Si(100)-2 × 1 as well as Ge(100)-2 × 1 reconstructed surfaces have been explored comprehensively through the dehydrogenation of ethane and ammonia-borane and their several analogues by employing density functional theory (DFT). From our study, it is evident that the termination of Si-surface via the dehydrogenation of aforementioned ethane and NHBH derivatives is more feasible compared to Ge-surface. For ethane, the investigation shows that the substitution of non-participat...

Towards a comprehensive understanding of the Si(100)-2×1 surface termination through hydrogen passivation using methylamine and methanol: a theoretical approach.

Using density functional theory, we explored the termination process of Si (100)-2 × 1 reconstructed surface mechanistically through the dehydrogenation of small molecules, considering methyl amine and methanol as terminating reagents. At first, both the terminating reagents form two types of adduct through adsorption on the Si (100)-2 × 1 surface, one in chemisorption mode and the other via physisorption, from which the dehydrogenation process is initiated. By analyzing the activation barriers, i...

Impacts of Early- and Late-Terminated Cover Crops on Gas Fluxes.

Cover crops (CCs) could alter soil processes, but the effects of early versus late termination of CCs on gas fluxes are not well known. We evaluated temporal changes in fluxes of CO, NO, and CH and related soil properties in no-till corn ( L.) with and without winter rye ( L.) CCs that were terminated early (30 d before planting) or late (at planting) in a rainfed silty clay loam and an irrigated silt loam in Nebraska from April 2016 to June 2017. Gas fluxes, soil temperature, and soil water content were me...

Security and efficiency enhancement of an anonymous three-party password-authenticated key agreement using extended chaotic maps.

Recently, Lu et al. claimed that Xie et al.'s three-party password-authenticated key agreement protocol (3PAKA) using chaotic maps has three security vulnerabilities; in particular, it cannot resist offline password guessing attack, Bergamo et al.'s attack and impersonation attack, and then they proposed an improved protocol. However, we demonstrate that Lu et al.'s attacks on Xie et al.'s scheme are unworkable, and their improved protocol is insecure against stolen-verifier attack and off-line password gue...

United States Medical Licensing Exam Step I Score as a Predictor of Neurosurgical Career Beyond Residency.

United States Medical Licensing Exam (USMLE) Step I score is cited as one of the most important factors when for applying to neurosurgery residencies. No studies have documented a correlation between USMLE Step I score and metrics of neurosurgical career trajectory beyond residency.

Construction of the Pentacyclic Core and Formal Total Synthesis of ()-Renieramycin T.

A formal total synthesis of the antitumor marine natural product ()-renieramycin T, which possesses a characteristic ecteinascidin-type A ring in the renieramycin-saframycin core skeleton, was elaborated. The key steps in the synthesis of ()-renieramycin T are a modified Pictet-Spengler cyclization of dialkylated oxomalonate derivatives and decarboxylation via a monocarboxylic acid derivative followed by stereocontrolled protonation of the enol intermediate. A key intermediate in our previous synthesi...

Agreement between mothers', fathers', and teachers' ratings of behavioural and emotional problems in 3-5-year-old children.

The Strengths and Difficulties Questionnaire (SDQ), a valid and reliable instrument for measuring children's mental health, is available in parent- and teacher versions, making it an ideal tool for assessing behavioural and emotional problems in young children. However, few studies have evaluated inter-parent agreement on the SDQ, and in most studies on SDQ agreement, parent scores are either provided by only one parent or have been combined into one parent score. Furthermore, studies on SDQ inter-rater agr...

Associations between graduated driver licensing and road trauma reductions in a later licensing age jurisdiction: Queensland, Australia.

The success of driver graduated licensing systems (GLS) is demonstrated primarily in jurisdictions that licence at young ages with requirements expiring at age 18. In Australia, GLS requirements typically apply for all applicants aged under 25. In 2007, the Queensland licensing system was strengthened, extending the learner and introducing a 100-hour supervised driving requirement, introducing restrictions on passenger carriage at night and high-powered vehicles for provisional drivers, and on phone use for...


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